KEGG   ORTHOLOGY: K02330Help
Entry
K02330                      KO                                     

Name
POLB
Definition
DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
Pathway
ko03410  Base excision repair
ko05166  Human T-cell leukemia virus 1 infection
ko05203  Viral carcinogenesis
Module
M00296  BER complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    K02330  POLB; DNA polymerase beta
 09160 Human Diseases
  09161 Cancers
   05203 Viral carcinogenesis
    K02330  POLB; DNA polymerase beta
  09167 Infectious diseases
   05166 HTLV-I infection
    K02330  POLB; DNA polymerase beta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K02330  POLB; DNA polymerase beta
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00296  BER complex
     K02330  POLB; DNA polymerase beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K02330  POLB; DNA polymerase beta
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.-  
     K02330  POLB; DNA polymerase beta
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Short Patch-BER factors
     K02330  POLB; DNA polymerase beta
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    X-family DNA polymerases
     K02330  POLB; DNA polymerase beta
BRITE hierarchy
Other DBs
GO: 0003887
Genes
HSA: 5423(POLB)
PTR: 737210(POLB)
PPS: 100990190(POLB)
GGO: 101144130(POLB)
PON: 100441812(POLB)
NLE: 100588738(POLB)
MCC: 704801(POLB)
MCF: 102115303(POLB)
CSAB: 103215689(POLB)
RRO: 104666045(POLB)
RBB: 108540714(POLB)
CJC: 100393825(POLB)
SBQ: 101046175(POLB)
MMU: 18970(Polb)
RNO: 29240(Polb)
CGE: 100774965(Polb)
NGI: 103726620(Polb)
HGL: 101710722(Polb)
CCAN: 109696397(Polb)
OCU: 100348691(POLB)
TUP: 102502435(POLB)
CFA: 494001(POLB)
AML: 100471432(POLB)
UMR: 103677058(POLB)
ORO: 101375051(POLB)
FCA: 101099797(POLB)
PTG: 102963455(POLB)
AJU: 106990013(POLB)
BTA: 614688(POLB)
BOM: 102281166(POLB)
BIU: 109553520(POLB)
PHD: 102337510(POLB)
CHX: 102177689(POLB)
OAS: 101122327(POLB)
SSC: 100526021(POLB)
CFR: 102508539(POLB)
CDK: 105086432(POLB)
BACU: 103013074(POLB)
LVE: 103088370(POLB)
OOR: 101286165(POLB)
ECB: 100050102(POLB)
EPZ: 103540388(POLB)
EAI: 106828958(POLB)
MYB: 102254615(POLB)
MYD: 102773539(POLB)
HAI: 109386265(POLB)
RSS: 109452856(POLB)
PALE: 102893018(POLB)
LAV: 100657074(POLB)
TMU: 101351696
MDO: 100030148(POLB)
SHR: 100929187(POLB)
OAA: 100078894(POLB)
GGA: 426794(POLB)
MGP: 100549334(POLB)
CJO: 107323743(POLB)
APLA: 101792343(POLB)
ACYG: 106044369(POLB)
TGU: 100221830(POLB)
GFR: 102035476(POLB)
FAB: 101818872(POLB)
PHI: 102100382(POLB)
PMAJ: 107213915(POLB)
CCW: 104694917(POLB)
FPG: 101922234(POLB)
FCH: 102058720(POLB)
CLV: 102087419(POLB)
EGZ: 104135297(POLB)
AAM: 106487777(POLB)
ASN: 102377806(POLB)
AMJ: 102561879(POLB)
PSS: 102449407(POLB)
CMY: 102931250(POLB)
CPIC: 101946448(POLB)
ACS: 100552750(polb)
PVT: 110072081(POLB)
PBI: 103066680(POLB)
GJA: 107120337(POLB)
XLA: 397973(polb.S)
XTR: 448741(polb)
NPR: 108791449(POLB)
DRE: 554204(polb)
SRX: 107722860 107754421(polb)
SGH: 107559597(polb) 107560038
IPU: 108265244(polb)
AMEX: 103039401(polb)
TRU: 101062869(polb)
LCO: 104921658(polb)
NCC: 104956689(polb)
MZE: 101474836(polb)
OLA: 101171171(polb)
XMA: 102224288(polb)
PRET: 103470029(polb)
NFU: 107394256(polb)
LCF: 108881626(polb)
HCQ: 109526786(polb)
BPEC: 110153402(polb)
SASA: 106580473 106585055(polb)
ELS: 105014301(polb)
SFM: 108920118(polb)
LCM: 102356930(POLB)
CMK: 103191220(polb)
CIN: 100177850
SPU: 582628
APLC: 110974494
SKO: 102807346
AME: 724170(GB18972)
BIM: 100748577
BTER: 100642507
SOC: 105198605
AEC: 105143443
ACEP: 105617439
PBAR: 105433787
HST: 105181480
CFO: 105252367
LHU: 105674311
PGC: 109852284
PMAC: 106709522
PRAP: 111002736
API: 100166716
DNX: 107173379
ZNE: 110832674
CRG: 105341699
MYI: 110451511
OBI: 106883258
LAK: 106168230
EPA: 110234390
AQU: 100639771
CNB: CNBA3870
DDI: DDB_G0284713(polB) DDB_G0284739(gxcFF)
DFA: DFA_04253(gxcFF)
SMIN: v1.2.005179.t1(symbB.v1.2.005179.t1)
VG: 11256689(mg586) 14445599(H012_gp414) 1449923(MSV117) 1494800(AMV210) 15613227(CHBEV_237) 15613530(CHREV_205) 15613855(MYSEV_233) 15614069(AHEV_140) 18263641(BA82_gp212) 20041712(JO84_gp044) 32290839(B9W72_gp416) 9887861(crov458) 9924935(L318)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC
  Title
The X family portrait: structural insights into biological functions of X family polymerases.
  Journal
DNA Repair (Amst) 6:1709-25 (2007)
DOI:10.1016/j.dnarep.2007.05.009
Reference
  Authors
DeMott MS, Beyret E, Wong D, Bales BC, Hwang JT, Greenberg MM, Demple B
  Title
Covalent trapping of human DNA polymerase beta by the oxidative DNA lesion 2-deoxyribonolactone.
  Journal
J Biol Chem 277:7637-40 (2002)
DOI:10.1074/jbc.C100577200
  Sequence
[hsa:5423]

DBGET integrated database retrieval system