K02539                      KO                                     

myeloid leukemia cell differntiation protein MCL-1
ko04151  PI3K-Akt signaling pathway
ko04210  Apoptosis
ko04630  JAK-STAT signaling pathway
ko05206  MicroRNAs in cancer
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
   04151 PI3K-Akt signaling pathway
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K02539  MCL1; myeloid leukemia cell differntiation protein MCL-1
HSA: 4170(MCL1)
PTR: 457274(MCL1)
PPS: 100979595(MCL1)
GGO: 101137633(MCL1)
PON: 100436188(MCL1)
NLE: 100604947(MCL1)
MCC: 707539(MCL1)
MCF: 101925224(MCL1)
CSAB: 103247197(MCL1)
RRO: 104681074(MCL1)
RBB: 108533266(MCL1)
CJC: 100406790(MCL1)
SBQ: 101046604(MCL1)
MMU: 17210(Mcl1)
MCAL: 110291321(Mcl1)
MPAH: 110320476(Mcl1)
RNO: 60430(Mcl1)
MUN: 110556651(Mcl1)
CGE: 100764237(Mcl1) 113836994
NGI: 103729108(Mcl1)
HGL: 101724340(Mcl1)
CCAN: 109681197(Mcl1)
OCU: 100359222(MCL1)
TUP: 102472561(MCL1)
CFA: 403537(MCL1)
VVP: 112907657(MCL1)
AML: 100484433(MCL1)
UMR: 103667602(MCL1)
UAH: 113246198(MCL1)
ORO: 101368348(MCL1) 101376217
FCA: 493970(MCL1)
PTG: 102965985(MCL1)
PPAD: 109256986(MCL1)
AJU: 106986653(MCL1)
BTA: 788087(MCL1)
BOM: 102277523 102283384(MCL1)
BIU: 109555382(MCL1) 109564155
BBUB: 102403565(MCL1)
CHX: 102185798(MCL1)
OAS: 554329(MCL1)
SSC: 397648(MCL1)
CFR: 102509345(MCL1)
CDK: 105103187(MCL1)
BACU: 103006100(MCL1)
LVE: 103090946(MCL1)
OOR: 101289701(MCL1)
DLE: 111169732(MCL1)
PCAD: 102993677 112061831(MCL1)
ECB: 100054765(MCL1)
EPZ: 103547666(MCL1)
EAI: 106846539(MCL1)
MYB: 102262272(MCL1)
MNA: 107539147(MCL1)
HAI: 109372291(MCL1)
DRO: 112313500(MCL1)
PALE: 102884014(MCL1)
RAY: 107499014(MCL1)
MJV: 108403236(MCL1)
LAV: 100676317(MCL1)
TMU: 101350934
MDO: 100017262(MCL1)
SHR: 100928648(MCL1)
PCW: 110220506(MCL1)
OAA: 114807992(MCL1)
GGA: 395674(MCL1)
MGP: 100540044(MCL1)
CJO: 107324527(MCL1)
NMEL: 110387955(MCL1)
ACYG: 106029353
TGU: 115498460(MCL1)
LSR: 110471539(MCL1)
PHI: 102111555(MCL1)
PMAJ: 107198998(MCL1)
FCH: 102058939(MCL1)
CLV: 102097620(MCL1)
NNI: 104020494(MCL1)
PADL: 103913345(MCL1)
AMJ: 102565309(MCL1)
CPIC: 101937549(MCL1)
ACS: 100556744(mcl1)
PVT: 110081542(MCL1)
PBI: 103056794(MCL1)
PMUR: 107292903(MCL1)
TSR: 106540600(MCL1)
PMUA: 114586110(MCL1)
XLA: 100192362(mcl1.L) 108700339(mcl1.S)
XTR: 100038211(mcl1)
NPR: 108789796(MCL1)
DRE: 58122(mcl1a)
TRU: 101069436
LCO: 104923932
NCC: 104944908
MZE: 101488044
OLA: 101165916
XMA: 102230859
XCO: 114141541
PRET: 103477645
CVG: 107084596
NFU: 107379220
KMR: 108243239
ALIM: 106524069
POV: 109633486
LCF: 108883179
SDU: 111222415
SLAL: 111669226
BPEC: 110162674
MALB: 109968964
LCM: 102350724(MCL1)
CMK: 103172502
RTP: 109924282
SPU: 582436
SKO: 100377406
PCAN: 112553808
OBI: 106869231
LAK: 106168952
HMG: 100215682(bcl-2)
 » show all
Bingle CD, Craig RW, Swales BM, Singleton V, Zhou P, Whyte MK
Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death.
J Biol Chem 275:22136-46 (2000)
Fujise K, Zhang D, Liu J, Yeh ET
Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen.
J Biol Chem 275:39458-65 (2000)

DBGET integrated database retrieval system