KEGG   ORTHOLOGY: K02733
Entry
K02733                      KO                                     
Symbol
PSMB10, MECL1
Name
20S proteasome subunit beta 10 [EC:3.4.25.1]
Pathway
map03050  Proteasome
Disease
H00092  T-B-Severe combined immunodeficiency
H02532  Proteasome-associated autoinflammatory syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03050 Proteasome
    K02733  PSMB10, MECL1; 20S proteasome subunit beta 10
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K02733  PSMB10, MECL1; 20S proteasome subunit beta 10
  09182 Protein families: genetic information processing
   03051 Proteasome
    K02733  PSMB10, MECL1; 20S proteasome subunit beta 10
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.25  Threonine endopeptidases
    3.4.25.1  proteasome endopeptidase complex
     K02733  PSMB10, MECL1; 20S proteasome subunit beta 10
Peptidases and inhibitors [BR:ko01002]
 Threonine peptidases
  Family T1: proteasome family
   K02733  PSMB10, MECL1; 20S proteasome subunit beta 10
Proteasome [BR:ko03051]
 Eukaryotic proteasome
  Core particles (20S proteasome)
   beta type subunits
    K02733  PSMB10, MECL1; 20S proteasome subunit beta 10
Genes
HSA: 5699(PSMB10)
PTR: 743176(PSMB10)
PPS: 100975072(PSMB10)
GGO: 101135626(PSMB10)
PON: 100434346(PSMB10)
PPYG: 129015651(PSMB10)
NLE: 100590167(PSMB10)
HMH: 116471406(PSMB10)
SSYN: 129492545(PSMB10)
MCC: 701088(PSMB10)
MCF: 102123642(PSMB10)
MTHB: 126944045
MNI: 105491397(PSMB10)
CSAB: 103233253(PSMB10)
CATY: 105585272(PSMB10)
PANU: 101026559(PSMB10)
TGE: 112614094(PSMB10)
MLEU: 105551482(PSMB10)
RRO: 104655610(PSMB10)
RBB: 108515386(PSMB10)
TFN: 117088471(PSMB10)
PTEH: 111541373(PSMB10)
CANG: 105504549(PSMB10)
CJC: 100393982(PSMB10)
SBQ: 101036568(PSMB10)
CIMI: 108311826(PSMB10)
ANAN: 105727963(PSMB10)
CSYR: 103268203(PSMB10)
MMUR: 105858974(PSMB10)
LCAT: 123625233(PSMB10)
PCOQ: 105823416(PSMB10)
OGA: 100942240(PSMB10)
MMU: 19171(Psmb10)
MCAL: 110300168(Psmb10)
MPAH: 110337585(Psmb10)
RNO: 291983(Psmb10)
MCOC: 116070082(Psmb10)
ANU: 117723130(Psmb10)
MUN: 110546249(Psmb10)
CGE: 100751737(Psmb10)
MAUA: 121136299(Psmb10)
PLEU: 114681057(Psmb10)
MORG: 121447298(Psmb10)
MFOT: 126502696
AAMP: 119802024(Psmb10)
NGI: 103738878(Psmb10)
HGL: 101701334(Psmb10)
CPOC: 100730197(Psmb10)
CCAN: 109691257(Psmb10)
DORD: 105983182(Psmb10)
DSP: 122126156(Psmb10)
PLOP: 125358273(Psmb10)
NCAR: 124967380
MMMA: 107150969(Psmb10)
OCU: 100353519
OPI: 101526650(PSMB10)
TUP: 102475003(PSMB10)
GVR: 103586113(PSMB10)
CFA: 489749(PSMB10)
CLUD: 112646518(PSMB10)
VVP: 112929440(PSMB10)
VLG: 121499331(PSMB10)
NPO: 129497053(PSMB10)
AML: 100468826(PSMB10)
UMR: 103673640(PSMB10)
UAH: 113252392(PSMB10)
UAR: 123803445(PSMB10)
ELK: 111152854
LLV: 125089100
MPUF: 101693618(PSMB10)
MNP: 132004920(PSMB10)
MLK: 131818652(PSMB10)
NVS: 122911322(PSMB10)
ORO: 101382081(PSMB10)
EJU: 114203475(PSMB10)
ZCA: 113936182(PSMB10)
MLX: 118023652(PSMB10)
NSU: 110592490(PSMB10)
LWW: 102734342(PSMB10)
FCA: 101082199(PSMB10)
PYU: 121045482(PSMB10)
PCOO: 112857370(PSMB10)
PBG: 122495126(PSMB10)
PVIV: 125153399(PSMB10)
LRUF: 124511417
PTG: 102971038(PSMB10)
PPAD: 109270746(PSMB10) 109270747
PUC: 125916277
AJU: 106972359
HHV: 120225301(PSMB10)
BTA: 282328(PSMB10)
BOM: 102264958(PSMB10)
BIU: 109572304(PSMB10)
BBUB: 102392749(PSMB10)
BBIS: 104996679(PSMB10)
CHX: 102189234(PSMB10)
OAS: 101116929(PSMB10)
BTAX: 128063493(PSMB10)
ODA: 120872742(PSMB10)
CCAD: 122421345(PSMB10)
MBEZ: 129546987(PSMB10)
SSC: 733626(PSMB10)
CFR: 102515419(PSMB10)
CBAI: 105074848(PSMB10)
CDK: 105088422(PSMB10)
VPC: 102535640(PSMB10)
BACU: 103016980(PSMB10)
BMUS: 118884757(PSMB10)
LVE: 103082949(PSMB10)
OOR: 101283341(PSMB10)
DLE: 111179615(PSMB10)
PCAD: 102995777(PSMB10)
PSIU: 116744303(PSMB10)
NASI: 112391386(PSMB10)
ECB: 100066381(PSMB10)
EPZ: 103549701(PSMB10)
EAI: 106822472(PSMB10)
MYB: 102262206(PSMB10)
MYD: 102766375(PSMB10)
MMYO: 118674158(PSMB10)
MLF: 102422814(PSMB10)
MDT: 132217447(PSMB10)
PKL: 118720518(PSMB10)
EFUS: 103284601(PSMB10)
MNA: 107527876(PSMB10)
DRO: 112300853(PSMB10)
SHON: 118983838(PSMB10)
AJM: 119061881(PSMB10)
PDIC: 114488113(PSMB10)
PHAS: 123805931(PSMB10)
MMF: 118638527(PSMB10)
PPAM: 129075076(PSMB10)
HAI: 109389612(PSMB10)
RFQ: 117032663 117034797(PSMB10)
PALE: 102882297(PSMB10)
PGIG: 120593892(PSMB10)
PVP: 105305740(PSMB10)
RAY: 107520413(PSMB10)
MJV: 108386442(PSMB10)
TOD: 119250359(PSMB10)
SARA: 101550541(PSMB10)
SETR: 126027430(PSMB10)
LAV: 104845440(PSMB10)
TMU: 101354564
ETF: 101660873(PSMB10)
DNM: 101434444(PSMB10)
MDO: 100021740(PSMB10)
GAS: 123234632(PSMB10)
SHR: 100914872(PSMB10)
AFZ: 127547876
PCW: 110210388(PSMB10)
TVP: 118845016(PSMB10)
OAA: 100073549(PSMB10)
DMO: Dmoj_GI26002
DAZ: 108615227
 » show all
Reference
PMID:16181324
  Authors
Strehl B, Seifert U, Kruger E, Heink S, Kuckelkorn U, Kloetzel PM
  Title
Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and MHC class I antigen processing.
  Journal
Immunol Rev 207:19-30 (2005)
DOI:10.1111/j.0105-2896.2005.00308.x
Reference
PMID:22341445
  Authors
Huber EM, Basler M, Schwab R, Heinemeyer W, Kirk CJ, Groettrup M, Groll M
  Title
Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
  Journal
Cell 148:727-38 (2012)
DOI:10.1016/j.cell.2011.12.030
  Sequence
[mmu:19171]

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (2)   
   KEGG DISEASE (2)   
Chemical reaction (1)   
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Gene (170)   
   KEGG GENES (157)   
   KEGG MGENES (7)   
   RefGene (5)   
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Literature (2)   
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