KEGG   ORTHOLOGY: K03012
Entry
K03012                      KO                                     

Name
RPB4, POLR2D
Definition
DNA-directed RNA polymerase II subunit RPB4
Pathway
ko03020  RNA polymerase
ko05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery
    K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
   03400 DNA repair and recombination proteins
    K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol II specific subunits
     K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      K03012  RPB4, POLR2D; DNA-directed RNA polymerase II subunit RPB4
Genes
HSA: 5433(POLR2D)
PTR: 100612569(POLR2D)
PPS: 100969259(POLR2D)
GGO: 101125758(POLR2D)
PON: 100443816(POLR2D)
NLE: 100596942(POLR2D)
MCC: 699945(POLR2D)
MCF: 102128431(POLR2D)
CSAB: 103216869(POLR2D)
RRO: 104662422(POLR2D)
RBB: 108533011
SBQ: 101039929(POLR2D)
MMU: 69241(Polr2d)
MCAL: 110284764(Polr2d)
MPAH: 110333300(Polr2d)
RNO: 364834(Polr2d)
CGE: 100755604(Polr2d)
NGI: 103724860(Polr2d)
HGL: 101703872(Polr2d)
CCAN: 109689483(Polr2d)
OCU: 100358254(POLR2D)
TUP: 102478451(POLR2D)
CFA: 483863(POLR2D)
VVP: 112932713(POLR2D)
AML: 100474413(POLR2D)
UMR: 103658564(POLR2D)
UAH: 113263493(POLR2D)
ORO: 101366902(POLR2D)
ELK: 111160866
FCA: 101092702(POLR2D)
PTG: 102961156(POLR2D)
PPAD: 109278810(POLR2D)
AJU: 106966414(POLR2D)
BTA: 617422(POLR2D)
BOM: 102275221(POLR2D)
BIU: 109565179(POLR2D)
BBUB: 102412943(POLR2D)
CHX: 102174167(POLR2D)
OAS: 101107845(POLR2D)
SSC: 100737579(POLR2D)
CFR: 102513049(POLR2D)
CDK: 105084493(POLR2D)
BACU: 103020416(POLR2D)
LVE: 103081335(POLR2D)
OOR: 101272373(POLR2D)
DLE: 111183343(POLR2D)
PCAD: 102984853(POLR2D)
ECB: 100069214(POLR2D)
EPZ: 103544757(POLR2D)
EAI: 106841529(POLR2D)
MYB: 102247603(POLR2D)
MYD: 102768392(POLR2D)
MNA: 107528577(POLR2D)
HAI: 109371821(POLR2D)
DRO: 112313098(POLR2D)
PALE: 102882561(POLR2D)
RAY: 107516873(POLR2D)
MJV: 108409812(POLR2D)
LAV: 100674544(POLR2D)
TMU: 101351631
MDO: 100018533(POLR2D)
SHR: 100935294(POLR2D)
PCW: 110194684(POLR2D)
OAA: 100087858(POLR2D)
GGA: 424754(POLR2D)
MGP: 100545646(POLR2D)
CJO: 107317953(POLR2D)
NMEL: 110397923(POLR2D)
APLA: 101793499(POLR2D)
ACYG: 106040344(POLR2D)
TGU: 100190224(POLR2D)
LSR: 110474547(POLR2D)
SCAN: 103815524(POLR2D)
GFR: 102038746(POLR2D)
FAB: 101805874(POLR2D)
PHI: 102110656(POLR2D)
PMAJ: 107208522(POLR2D)
CCAE: 111933815(POLR2D)
CCW: 104693072(POLR2D)
ETL: 114065418(POLR2D)
FPG: 101917848(POLR2D)
FCH: 102056159(POLR2D)
CLV: 102083809(POLR2D)
EGZ: 104126905(POLR2D)
NNI: 104008601(POLR2D)
ACUN: 113483749(POLR2D)
PADL: 103912817(POLR2D)
AAM: 106484453(POLR2D)
ASN: 102381772(POLR2D)
AMJ: 102567542(POLR2D)
PSS: 102459735(POLR2D)
CMY: 102933530(POLR2D)
CPIC: 101952288(POLR2D)
ACS: 100567905(polr2d)
PVT: 110075842(POLR2D)
PBI: 103066577(POLR2D)
PMUR: 107287669(POLR2D)
TSR: 106540906(POLR2D)
PMUA: 114597642(POLR2D)
GJA: 107123589(POLR2D)
XLA: 447138(polr2d.L)
XTR: 549002(polr2d)
NPR: 108792669(POLR2D)
DRE: 436588(polr2d)
SGH: 107562867(polr2d)
CCAR: 109047406 109078689(polr2d)
IPU: 100528773(polr2d)
PHYP: 113526754(polr2d)
AMEX: 103029206(polr2d)
EEE: 113589211(polr2d)
TRU: 101078995(polr2d)
LCO: 104939357(polr2d)
MZE: 101467986(polr2d)
ONL: 100711617(polr2d)
OLA: 101165515(polr2d)
XMA: 102233003(polr2d)
XCO: 114161780(polr2d)
PRET: 103475267(polr2d)
CVG: 107102714(polr2d)
NFU: 107379920(polr2d)
KMR: 108229006(polr2d)
AOCE: 111573562(polr2d)
CSEM: 103382632(polr2d)
POV: 109644898(polr2d)
SDU: 111216854(polr2d)
SLAL: 111663361(polr2d)
HCQ: 109514618(polr2d)
BPEC: 110160794(polr2d)
MALB: 109972734(polr2d)
SASA: 100286604(rpb4) 106612892
ELS: 105010716(polr2d)
SFM: 108926813(polr2d)
PKI: 111836539(polr2d)
LCM: 102345288(POLR2D)
CMK: 103172396(polr2d)
RTP: 109911749(polr2d)
BFO: 118430538
CIN: 100182759
SPU: 591189
APLC: 110979006
SKO: 100377865
DME: Dmel_CG43662(Rpb4) Dmel_CG43663(Ada2a)
DER: 6551909
MDE: 101899821
AAG: 5568219
ACEP: 105624475
PBAR: 105429278
VEM: 105561217
HST: 105189103
DQU: 106747964
CFO: 105251761
NVI: 100115771
CSOL: 105360682
BMOR: 101740659
BMAN: 114248156
PMAC: 106717879
PRAP: 110992350
HAW: 110375872
TNL: 113498544
PXY: 105393013
DNX: 107164802
RMD: 113557167
BTAB: 109041037
CLEC: 106663200
FCD: 110846247
DPTE: 113791666
PTEP: 107450061
CEL: CELE_F43E2.2(rpb-4)
CBR: CBG13151(Cbr-rpb-4)
BMY: Bm1_25045
PCAN: 112557229
CRG: 105317502
MYI: 110446843
OBI: 106876036
SHX: MS3_01939
EGL: EGR_06882
NVE: 5512572
EPA: 110252122
ADF: 107333898
AMIL: 114962011
PDAM: 113679160
DGT: 114518445
AQU: 100639910
ATH: AT5G09920(NRPB4)
LJA: Lj0g3v0122329.1(Lj0g3v0122329.1) Lj3g3v0744700.1(Lj3g3v0744700.1) Lj6g3v1707190.1(Lj6g3v1707190.1)
DOSA: Os02t0116900-01(Os02g0116900) Os02t0723300-01(Os02g0723300)
ATS: 109731594(LOC109731594) 109758329(LOC109758329) 109767350(LOC109767350) 109783686(LOC109783686)
ZMA: 100191330(TIDP3101) 100282338
PPP: 112286627
APRO: F751_4131
SCE: YJL140W(RPB4)
ERC: Ecym_5193
KMX: KLMA_10351(RPB4)
NCS: NCAS_0B08160(NCAS0B08160)
NDI: NDAI_0A01080(NDAI0A01080)
TPF: TPHA_0B03010(TPHA0B03010)
TBL: TBLA_0B06500(TBLA0B06500)
TDL: TDEL_0H00900(TDEL0H00900)
KAF: KAFR_0F01950(KAFR0F01950)
PIC: PICST_58607(RPB4)
CAL: CAALFM_C204650CA(RPB4)
NCR: NCU09378
NTE: NEUTE1DRAFT114768(NEUTE1DRAFT_114768)
MGR: MGG_04508
SSCK: SPSK_08051
MAW: MAC_05288
MAJ: MAA_03940
CMT: CCM_06882
BFU: BCIN_15g00340(Bcrpb4)
MBE: MBM_00072
ANG: ANI_1_1596024(An02g11470)
ABE: ARB_03624
TVE: TRV_01945
PTE: PTT_08920
SPO: SPBC337.14(rpb4)
CNE: CND05580
CNB: CNBD0780
TASA: A1Q1_05449
MGL: MGL_1968
MRT: MRET_1500
DDI: DDB_G0282739(rpb4)
DFA: DFA_01521(rpb4)
PCB: PCHAS_030540(PC000766.03.0)
TAN: TA12735
TPV: TP02_0359
BBO: BBOV_III006040(17.m07533)
CPV: cgd3_4320
TGO: TGME49_231380(POLR2D)
SPAR: SPRG_03275
 » show all
Reference
PMID:9528765
  Authors
Khazak V, Estojak J, Cho H, Majors J, Sonoda G, Testa JR, Golemis EA
  Title
Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II.
  Journal
Mol Cell Biol 18:1935-45 (1998)
DOI:10.1128/mcb.18.4.1935
  Sequence
[hsa:5433]
Reference
PMID:9852112
  Authors
Kershnar E, Wu SY, Chiang CM
  Title
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
  Journal
J Biol Chem 273:34444-53 (1998)
DOI:10.1074/jbc.273.51.34444
  Sequence
[hsa:5433]
Reference
  Authors
Li S, Smerdon MJ
  Title
Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae.
  Journal
EMBO J 21:5921-9 (2002)
DOI:10.1093/emboj/cdf589
  Sequence
[sce:YJL140W]

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