KEGG   ORTHOLOGY: K03016Help
Entry
K03016                      KO                                     

Name
RPB8, POLR2H
Definition
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03020  RNA polymerase
ko04623  Cytosolic DNA-sensing pathway
ko05016  Huntington's disease
ko05169  Epstein-Barr virus infection
Module
M00180  RNA polymerase II, eukaryotes
M00181  RNA polymerase III, eukaryotes
M00182  RNA polymerase I, eukaryotes
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
   00240 Pyrimidine metabolism
    K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
 Genetic Information Processing
  Transcription
   03020 RNA polymerase
    K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
 Organismal Systems
  Immune system
   04623 Cytosolic DNA-sensing pathway
    K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
 Human Diseases
  Neurodegenerative diseases
   05016 Huntington's disease
    K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
  Infectious diseases
   05169 Epstein-Barr virus infection
    K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   RNA polymerase
    M00180  RNA polymerase II, eukaryotes
     K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
    M00181  RNA polymerase III, eukaryotes
     K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
    M00182  RNA polymerase I, eukaryotes
     K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
  RNA polymerase III system
   RNA polymerase III
    Pol I, II, III common subunits
     K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
  RNA polymerase I system
   RNA polymerase I
    Pol I, II, III common subunits
     K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      K03016  RPB8, POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
BRITE hierarchy
Other DBs
RN: R00435 R00441 R00442 R00443
Genes
HSA: 5437(POLR2H)
PTR: 471027(POLR2H)
PPS: 100980213(POLR2H)
GGO: 101154168(POLR2H)
PON: 100452428(POLR2H)
NLE: 100582655(POLR2H)
MCC: 100429040(POLR2H)
MCF: 102140336(POLR2H)
CSAB: 103221131(POLR2H)
RRO: 104664622(POLR2H)
RBB: 108525206(POLR2H)
CJC: 100394075(POLR2H)
SBQ: 101046822(POLR2H)
MMU: 245841(Polr2h)
RNO: 100912534 498109(Polr2h)
CGE: 100769706(Polr2h)
NGI: 103732659(Polr2h)
HGL: 101706663(Polr2h)
CCAN: 109694099(Polr2h)
OCU: 100347834(POLR2H)
TUP: 106736235(POLR2H)
CFA: 478656(POLR2H)
AML: 100470168(POLR2H)
UMR: 103676079(POLR2H)
ORO: 101373084(POLR2H)
FCA: 101084389(POLR2H)
PTG: 102968963(POLR2H)
AJU: 106983811(POLR2H)
BTA: 505599(POLR2H)
BOM: 102275957(POLR2H)
BIU: 109557349(POLR2H)
PHD: 102315832(POLR2H)
CHX: 102182068(POLR2H)
OAS: 101119867(POLR2H)
SSC: 100628241(POLR2H)
CFR: 102521897(POLR2H)
CDK: 105085875(POLR2H)
BACU: 103001378(POLR2H)
LVE: 103088960(POLR2H)
OOR: 101275030(POLR2H)
ECB: 100059115(POLR2H)
EPZ: 103554737(POLR2H)
EAI: 106834516(POLR2H)
MYB: 102245238(POLR2H)
MYD: 102769153(POLR2H)
HAI: 109396799(POLR2H)
RSS: 109449484(POLR2H)
PALE: 102878376(POLR2H)
LAV: 100676232(POLR2H)
TMU: 101356817
MDO: 100013916(POLR2H)
SHR: 100933932(POLR2H)
OAA: 100089660(POLR2H)
GGA: 424954(POLR2H)
MGP: 100545178(POLR2H)
CJO: 107318259(POLR2H)
APLA: 101792967(POLR2H)
TGU: 100190016(POLR2H)
GFR: 102031433(POLR2H)
FAB: 101806753(POLR2H)
PHI: 102109122(POLR2H)
PMAJ: 107209007(POLR2H)
CCW: 104687986(POLR2H)
FPG: 101913371(POLR2H)
FCH: 102060193(POLR2H)
CLV: 102089188(POLR2H)
EGZ: 104122290(POLR2H)
AAM: 106482255 106494211(POLR2H)
ASN: 102380713(POLR2H)
AMJ: 102574727(POLR2H)
PSS: 102459209(POLR2H)
CMY: 102935557(POLR2H)
CPIC: 101948266(POLR2H)
ACS: 100555951(polr2h)
PVT: 110089822(POLR2H)
PBI: 103062347(POLR2H)
GJA: 107123682(POLR2H)
XLA: 108718026(polr2h.S) 443896(polr2h.L)
XTR: 548867(polr2h)
NPR: 108804657(POLR2H)
DRE: 550263(polr2h)
SRX: 107731657(polr2h) 107732651
CCAR: 109080980(polr2h)
IPU: 100528377(polr2h)
AMEX: 103046918(polr2h)
TRU: 101079851(polr2h)
LCO: 104927504(polr2h)
NCC: 104961920(polr2h)
MZE: 101486540(polr2h)
OLA: 101159426(polr2h)
XMA: 102229592(polr2h)
PRET: 103463459(polr2h)
NFU: 107392756(polr2h)
CSEM: 103394099(polr2h)
LCF: 108881225(polr2h)
BPEC: 110160197(polr2h)
SASA: 100286712(polr2h)
ELS: 105026920(polr2h)
SFM: 108921679(polr2h)
LCM: 102364801(POLR2H)
CMK: 103184435(polr2h)
CIN: 100178283
SPU: 591688
APLC: 110983881
SKO: 100370657
DME: Dmel_CG11246(Rpb8)
DSI: Dsimw501_GD14989(Dsim_GD14989)
MDE: 101895411
AAG: 5565447
AME: 102655904
BIM: 105680630
BTER: 105665726
SOC: 105200408
AEC: 105143874
ACEP: 105620560
PBAR: 105431087
HST: 105185593
CFO: 105252932
LHU: 105675987
PGC: 109859413
NVI: 100115406
TCA: 658676
DPA: 109542690
NVL: 108560253
BMOR: 101744611
PMAC: 106713416
PRAP: 111002451
API: 100169136(Polr2h)
DNX: 107162624
ZNE: 110827651
FCD: 110843124
CEL: CELE_F26F4.11(rpb-8)
CBR: CBG18189(Cbr-rpb-8)
BMY: Bm1_26995
TSP: Tsp_00326
CRG: 105330854
MYI: 110464273
OBI: 106867543
LAK: 106179848
SHX: MS3_01594
EPA: 110237977
ADF: 107341034
HMG: 100203045
ATH: AT1G54250(NRPB8A) AT3G59600(NRPB8B)
BRP: 103841806
BOE: 106309990
LJA: Lj0g3v0150319.1(Lj0g3v0150319.1) Lj0g3v0150319.2(Lj0g3v0150319.2) Lj0g3v0150319.3(Lj0g3v0150319.3) Lj0g3v0270299.1(Lj0g3v0270299.1) Lj0g3v0270299.2(Lj0g3v0270299.2) Lj5g3v0975900.1(Lj5g3v0975900.1) Lj5g3v0975900.2(Lj5g3v0975900.2)
RCU: 8263166
CANN: 107868305
BVG: 104889864
NNU: 104605253
DOSA: Os03t0845700-01(Os03g0845700) Os06t0697400-01(Os06g0697400)
ATS: 109737850(LOC109737850) 109783265(LOC109783265)
ZMA: 100281008(pco144871)
PDA: 103699115
EGU: 105060651
MUS: 103998751
AOF: 109832463
ATR: 18448978
PPP: 112295370
CRE: CHLREDRAFT_126483(RPB8)
MNG: MNEG_7835
APRO: F751_6084
SCE: YOR224C(RPB8)
ERC: Ecym_8331
KMX: KLMA_20792(RPB8)
NCS: NCAS_0B01380(NCAS0B01380)
NDI: NDAI_0E01380(NDAI0E01380)
TPF: TPHA_0F03280(TPHA0F03280)
TBL: TBLA_0J00350(TBLA0J00350)
TDL: TDEL_0A05920(TDEL0A05920)
KAF: KAFR_0G01860(KAFR0G01860)
PIC: PICST_87046(RPB8)
CAL: CAALFM_CR04780WA(RPB8)
CAUR: QG37_08338
SLB: AWJ20_18(RPB8)
NCR: NCU08030
MGR: MGG_07080
MAJ: MAA_02710
CMT: CCM_00394
BFU: BCIN_12g02760(Bcrpb8)
MBE: MBM_06705
ANI: AN0192.2
ANG: ANI_1_286014(An01g02200)
ABE: ARB_03020
TVE: TRV_04927
PTE: PTT_04001
SPO: SPBC14C8.12(rpb8)
CNE: CNI02630
CNB: CNBH2490
MRR: Moror_107
ABP: AGABI1DRAFT117227(AGABI1DRAFT_117227)
ABV: AGABI2DRAFT197624(AGABI2DRAFT_197624)
MGL: MGL_3267
DDI: DDB_G0278039(rpb8)
DFA: DFA_08762(rpb8)
EHI: EHI_038570(7.t00016)
PYO: PY17X_1431700(PY02017)
PCB: PCHAS_143140(PC000459.03.0)
TAN: TA19535
TPV: TP01_0233
BBO: BBOV_IV005100(23.m06188)
CPV: cgd1_2260
TGO: TGME49_233720(POLR2H)
SMIN: v1.2.027601.t1(symbB.v1.2.027601.t1)
TPS: THAPSDRAFT_38815(Rpb8)
SPAR: SPRG_12350
TCR: 506933.80
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9852112
  Authors
Kershnar E, Wu SY, Chiang CM
  Title
Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.
  Journal
J Biol Chem 273:34444-53 (1998)
DOI:10.1074/jbc.273.51.34444
  Sequence
[hsa:5437]
Reference
  Authors
Engel C, Sainsbury S, Cheung AC, Kostrewa D, Cramer P
  Title
RNA polymerase I structure and transcription regulation.
  Journal
Nature 502:650-5 (2013)
DOI:10.1038/nature12712
  Sequence
[sce:YOR224C]

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