KEGG   ORTHOLOGY: K03094Help
Entry
K03094                      KO                                     

Name
SKP1, CBF3D
Definition
S-phase kinase-associated protein 1
Pathway
ko04110  Cell cycle
ko04111  Cell cycle - yeast
ko04114  Oocyte meiosis
ko04120  Ubiquitin mediated proteolysis
ko04141  Protein processing in endoplasmic reticulum
ko04310  Wnt signaling pathway
ko04341  Hedgehog signaling pathway - fly
ko04350  TGF-beta signaling pathway
ko04710  Circadian rhythm
ko05168  Herpes simplex infection
ko05200  Pathways in cancer
Module
M00379  SCF-MET30 complex
M00380  SCF-BTRC complex
M00381  SCF-SKP2 complex
M00382  SCF-FBS complex
M00387  SCF-FBW7 complex
M00407  SCF-CDC4 complex
M00411  SCF-GRR1 complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04120 Ubiquitin mediated proteolysis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04341 Hedgehog signaling pathway - fly
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04350 TGF-beta signaling pathway
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04111 Cell cycle - yeast
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   04114 Oocyte meiosis
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Organismal Systems
  Environmental adaptation
   04710 Circadian rhythm
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
  Infectious diseases
   05168 Herpes simplex infection
    K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Ubiquitin system
    M00379  SCF-MET30 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00380  SCF-BTRC complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00381  SCF-SKP2 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00382  SCF-FBS complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00407  SCF-CDC4 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00411  SCF-GRR1 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
    M00387  SCF-FBW7 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   SCF complex
    Adaptor protein
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
   Cul7 complex
    Adaptor protein
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   Kinetochore proteins
    CBF3 complex
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
BRITE hierarchy
Other DBs
COG: COG5201
Genes
HSA: 6500(SKP1)
PTR: 462063(SKP1)
PPS: 100981953(SKP1) 106635345
GGO: 101148010 101150703(SKP1)
PON: 100174716(SKP1)
NLE: 100596865(SKP1)
MCC: 100423634(SKP1)
MCF: 102142637(SKP1)
CSAB: 103244544(SKP1)
RRO: 104659810(SKP1) 104677263
CJC: 100398187(SKP1)
SBQ: 101030146(SKP1)
MMU: 21402(Skp1a)
RNO: 287280(Skp1)
CGE: 100757677(Skp1)
NGI: 103729775(Skp1)
HGL: 101704606(Skp1)
CCAN: 109689481(Skp1)
OCU: 100339463(SKP1)
TUP: 102483646(SKP1) 102487314
CFA: 474682(SKP1)
AML: 100463880(SKP1)
UMR: 103663817(SKP1)
ORO: 101374307 101386391(SKP1)
FCA: 101099017(SKP1)
PTG: 102957702(SKP1)
AJU: 106984903(SKP1)
BTA: 615427(SKP1)
BOM: 102266347(SKP1)
BIU: 109562016(SKP1)
PHD: 102334121 102337635(SKP1)
CHX: 102174738 108633185(SKP1)
OAS: 100240716(SKP1)
SSC: 100520183
CFR: 102519293(SKP1)
CDK: 105090262(SKP1)
BACU: 103011520 103018727(SKP1)
LVE: 103074429(SKP1) 103090703
OOR: 101289355(SKP1)
ECB: 100062946(SKP1)
EPZ: 103543154(SKP1)
EAI: 106834656(SKP1)
MYB: 102251595(SKP1) 102251629
MYD: 102756513(SKP1)
HAI: 109382554(SKP1)
PALE: 102885538(SKP1)
LAV: 100663845(SKP1)
TMU: 101350591
MDO: 100014810(SKP1)
SHR: 100927300(SKP1)
OAA: 100082731(SKP1)
GGA: 416319(SKP1)
MGP: 100544772(SKP1)
CJO: 107320209(SKP1)
APLA: 101803413(SKP1)
ACYG: 106032826(SKP1)
TGU: 100225726(SKP1)
GFR: 102038546(SKP1)
FAB: 101813841(SKP1)
PHI: 102099878(SKP1)
PMAJ: 107210641(SKP1)
CCW: 104683717(SKP1)
FPG: 101911889(SKP1)
FCH: 102046372(SKP1)
CLV: 102094112(SKP1)
EGZ: 104133458(SKP1)
AAM: 106487187(SKP1)
ASN: 102382934(SKP1)
AMJ: 102576679(SKP1)
PSS: 102446427(SKP1)
CMY: 102935126(SKP1)
CPIC: 101936963(SKP1)
ACS: 100568037(skp1)
PVT: 110079401(SKP1)
PBI: 103066791(SKP1)
GJA: 107125984(SKP1)
XLA: 108712619 380538(skp1.S)
XTR: 549273(skp1)
NPR: 108792127(SKP1)
DRE: 393716(skp1)
SRX: 107728271 107742439(skp1)
SANH: 107661767(skp1) 107692975
SGH: 107580163 107603266(skp1)
CCAR: 109048021(skp1) 109067897
IPU: 100528639(skp1)
AMEX: 103045526(skp1)
TRU: 101068627(skp1)
LCO: 104924374(skp1)
NCC: 104957032(skp1)
MZE: 101469121(skp1)
OLA: 101173567(skp1)
XMA: 102221489(skp1)
PRET: 103459979(skp1)
NFU: 107386838(skp1)
CSEM: 103394863(skp1)
LCF: 108893670(skp1)
HCQ: 109515642(skp1)
BPEC: 110153983(skp1)
SASA: 100195936(skp1) 106567526(SKP1)
ELS: 105026694(skp1)
LCM: 102350053(SKP1)
CMK: 103182116 103183679(skp1)
CIN: 100181511
SPU: 594639
APLC: 110980531
SKO: 100313722
DME: Dmel_CG11941(SkpC) Dmel_CG11942(SkpE) Dmel_CG12227(SkpF) Dmel_CG12700(SkpD) Dmel_CG15800(CG15800) Dmel_CG16983(SkpA) Dmel_CG43089(CG43089) Dmel_CG8881(SkpB)
DSI: Dsimw501_GD16521(Dsim_GD16521) Dsimw501_GD17469(Dsim_GD17469) Dsimw501_GD25016(Dsim_GD25016) Dsimw501_GD25046(Dsim_GD25046) Dsimw501_GD25859(Dsim_GD25859) Dsimw501_GD29572(Dsim_GD29572)
MDE: 101898001
AAG: 5571571
AME: 409234(p19skp1)
BIM: 100743026
BTER: 100651427
SOC: 105195125
ACEP: 105626331
PBAR: 105427532
HST: 105187367
LHU: 105672747
PGC: 109853127
NVI: 100119117(Skp1) 103316687
TCA: 663380(skp1)
DPA: 109545243
NVL: 108559854
BMOR: 733106
PMAC: 106708696
PRAP: 110992864
PXY: 105397971
DNX: 107161275
ZNE: 110835390
TUT: 107361622
CEL: CELE_C06A8.4(skr-17) CELE_C42D4.6(skr-16) CELE_C52D10.6(skr-12) CELE_C52D10.7(skr-9) CELE_C52D10.8(skr-13) CELE_C52D10.9(skr-8) CELE_F44G3.6(skr-3) CELE_F46A9.4(skr-2) CELE_F46A9.5(skr-1) CELE_F47H4.10(skr-5) CELE_F54D10.1(skr-15) CELE_F56B3.12(skr-18) CELE_K08H2.1(skr-21) CELE_R12H7.3(skr-19) CELE_R12H7.5(skr-20) CELE_Y105C5B.13(skr-10) CELE_Y37H2C.2(skr-6) CELE_Y47D7A.1(skr-7) CELE_Y47D7A.8(skr-14) CELE_Y60A3A.18(skr-4)
CRG: 105325178
MYI: 110444357
OBI: 106875753
LAK: 106181029
SHX: MS3_04896
EPA: 110242232
ATH: AT1G10230(SK18) AT1G20140(SK4) AT1G75950(SKP1) AT2G03160(SK19) AT2G03170(SK14) AT2G03190(SK16) AT2G20160(MEO) AT2G25700(SK3) AT3G21830(SK8) AT3G21840(SK7) AT3G21850(SK9) AT3G21860(SK10) AT3G25650(SK15) AT3G53060(SK6) AT3G60010(SK13) AT3G60020(SK5) AT4G34210(SK11) AT4G34470(SK12) AT5G42190
LJA: Lj0g3v0079709.1(Lj0g3v0079709.1) Lj0g3v0106769.1(Lj0g3v0106769.1) Lj0g3v0259179.1(Lj0g3v0259179.1) Lj0g3v0261809.1(Lj0g3v0261809.1) Lj0g3v0349889.1(Lj0g3v0349889.1) Lj1g3v2671420.4(Lj1g3v2671420.4) Lj2g3v1267140.1(Lj2g3v1267140.1) Lj2g3v1670950.1(Lj2g3v1670950.1) Lj2g3v3084320.1(Lj2g3v3084320.1) Lj4g3v2366270.2(Lj4g3v2366270.2) Lj5g3v0186670.1(Lj5g3v0186670.1) Lj5g3v0186680.1(Lj5g3v0186680.1) Lj5g3v2242520.1(Lj5g3v2242520.1) Lj5g3v2243530.1(Lj5g3v2243530.1)
DOSA: Os02t0101600-00(Os02g0101600) Os02t0225100-00(Os02g0225100) Os06t0113800-00(Os06g0113800) Os07t0144900-01(Os07g0144900) Os07t0409500-01(Os07g0409500) Os07t0624900-00(Os07g0624900) Os07t0625400-01(Os07g0625400) Os07t0625500-01(Os07g0625500) Os07t0625600-00(Os07g0625600) Os08t0375500-00(Os08g0375500) Os08t0375700-00(Os08g0375700) Os09t0272900-01(Os09g0272900) Os09t0273800-01(Os09g0273800) Os09t0274800-00(Os09g0274800) Os09t0275200-01(Os09g0275200) Os09t0412050-00(Os09g0412050) Os09t0539500-01(Os09g0539500) Os10t0438100-00(Os10g0438100) Os11t0456300-01(Os11g0456300)
ATS: 109731751(LOC109731751) 109731752(LOC109731752) 109736328(LOC109736328) 109736331(LOC109736331) 109736344(LOC109736344) 109738030(LOC109738030) 109738826(LOC109738826) 109739276(LOC109739276) 109739861(LOC109739861) 109739863(LOC109739863) 109741013(LOC109741013) 109741575(LOC109741575) 109745567(LOC109745567) 109747449(LOC109747449) 109757294(LOC109757294) 109765120(LOC109765120) 109765502(LOC109765502) 109765503(LOC109765503) 109765504(LOC109765504) 109765505(LOC109765505) 109765506(LOC109765506) 109767474(LOC109767474) 109767932(LOC109767932) 109768388(LOC109768388) 109772398(LOC109772398) 109773898(LOC109773898) 109777844(LOC109777844) 109777845(LOC109777845) 109777916(LOC109777916) 109778508(LOC109778508) 109778923(LOC109778923) 109779096(LOC109779096) 109780380(LOC109780380) 109783394(LOC109783394) 109784277(LOC109784277) 109786254(LOC109786254)
CRE: CHLREDRAFT_128004(SKP1)
MNG: MNEG_0264
APRO: F751_1451
SCE: YDR328C(SKP1)
ERC: Ecym_8162
KMX: KLMA_60103(SKP1)
NCS: NCAS_0F02970(NCAS0F02970)
NDI: NDAI_0C04420(NDAI0C04420)
TPF: TPHA_0D02190(TPHA0D02190)
TBL: TBLA_0H01860(TBLA0H01860)
TDL: TDEL_0E02570(TDEL0E02570)
KAF: KAFR_0D04400(KAFR0D04400)
CAL: CAALFM_C107410CA(SKP1)
CAUR: QG37_05306
NCR: NCU08991(scon-3)
NTE: NEUTE1DRAFT117111(NEUTE1DRAFT_117111)
MGR: MGG_04978
TRE: TRIREDRAFT_73823(skp1)
MAW: MAC_03119
CMT: CCM_02669
BFU: BCIN_03g01890(Bcskp1)
MBE: MBM_03677
ANI: AN2302.2
ABE: ARB_06761
TVE: TRV_03348
PTE: PTT_18813
SPO: SPBC409.05(skp1)
CNE: CNA08080
CNB: CNBA7900
ABP: AGABI1DRAFT111082(AGABI1DRAFT_111082)
ABV: AGABI2DRAFT190295(AGABI2DRAFT_190295)
MGL: MGL_3474
DDI: DDB_G0269230(fpaA) DDB_G0273251(fpaB-1) DDB_G0273615(fpaB-2)
DFA: DFA_07127(fpaA) DFA_12090
EHI: EHI_065310 EHI_066770(181.t00006) EHI_118670(62.t00027) EHI_134960(153.t00018) EHI_174130(116.t00012) EHI_174180(116.t00016)
PYO: PY17X_1144200(PY00081)
PCB: PCHAS_114240(PC302606.00.0)
TAN: TA03425
TPV: TP03_0225
BBO: BBOV_IV006860(23.m05921)
CPV: cgd7_2500
SMIN: v1.2.020751.t1(symbB.v1.2.020751.t1) v1.2.021574.t1(symbB.v1.2.021574.t1)
PTI: PHATRDRAFT_17276(Skp1_1)
VG: 16512567(pdul_cds_894) 16607219(psal_cds_1160)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Petroski MD, Deshaies RJ.
  Title
Function and regulation of cullin-RING ubiquitin ligases.
  Journal
Nat Rev Mol Cell Biol 6:9-20 (2005)
DOI:10.1038/nrm1547
Reference
PMID:8706131
  Authors
Bai C, Sen P, Hofmann K, Ma L, Goebl M, Harper JW, Elledge SJ
  Title
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.
  Journal
Cell 86:263-74 (1996)
DOI:10.1016/S0092-8674(00)80098-7
  Sequence
[sce:YDR328C]

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