KEGG   ORTHOLOGY: K03161Help
Entry
K03161                      KO                                     

Name
TNFSF5, CD40L, CD154
Definition
tumor necrosis factor ligand superfamily member 5
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04064  NF-kappa B signaling pathway
ko04514  Cell adhesion molecules (CAMs)
ko04660  T cell receptor signaling pathway
ko04672  Intestinal immune network for IgA production
ko05144  Malaria
ko05145  Toxoplasmosis
ko05310  Asthma
ko05320  Autoimmune thyroid disease
ko05322  Systemic lupus erythematosus
ko05330  Allograft rejection
ko05340  Primary immunodeficiency
ko05416  Viral myocarditis
Disease
H00093  Combined immunodeficiencies (CIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   04514 Cell adhesion molecules (CAMs)
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   04672 Intestinal immune network for IgA production
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
 Human Diseases
  Immune diseases
   05310 Asthma
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   05322 Systemic lupus erythematosus
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   05320 Autoimmune thyroid disease
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   05330 Allograft rejection
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   05340 Primary immunodeficiency
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
  Cardiovascular diseases
   05416 Viral myocarditis
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
  Infectious diseases
   05144 Malaria
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
   05145 Toxoplasmosis
    K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K03161  TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
CD molecules [BR:ko04090]
 Proteins
  K03161  CD154, CD40LG; tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome)
BRITE hierarchy
Other DBs
GO: 0005174 0005164
Genes
HSA: 959(CD40LG)
PTR: 473802(CD40LG)
PPS: 100975410(CD40LG)
GGO: 101152672(CD40LG)
PON: 100434130(CD40LG)
NLE: 100594974(CD40LG)
MCC: 574160(CD40LG)
MCF: 102138630(CD40LG)
CSAB: 103232640(CD40LG)
RRO: 104682444(CD40LG)
RBB: 108542673(CD40LG)
CJC: 100390012(CD40LG)
SBQ: 101051030(CD40LG)
MMU: 21947(Cd40lg)
RNO: 84349(Cd40lg)
CGE: 100763089(Cd40lg)
NGI: 103740147(Cd40lg)
HGL: 101700616(Cd40lg)
CCAN: 109681519(Cd40lg)
OCU: 100358388(CD40LG)
TUP: 102488619(CD40LG)
CFA: 403468(CD40LG)
AML: 100467917(CD40LG)
UMR: 103672841(CD40LG)
ORO: 101382563(CD40LG)
FCA: 493850(CD40LG)
PTG: 102969350(CD40LG)
AJU: 106985488(CD40LG)
BTA: 282387(CD40LG)
BOM: 102269787(CD40LG)
BIU: 109555532(CD40LG)
PHD: 102320409(CD40LG)
CHX: 102172335(CD40LG)
OAS: 767628(CD40LG)
SSC: 397231(CD40LG)
CFR: 102520018(CD40LG)
CDK: 105101647(CD40LG)
BACU: 103011748(CD40LG)
LVE: 103070177(CD40LG)
OOR: 101274859(CD40LG)
ECB: 100054624(CD40LG)
EPZ: 103541553(CD40LG)
EAI: 106825790(CD40LG)
MYB: 102255985(CD40LG)
MYD: 102762217(CD40LG)
HAI: 109396161(CD40LG)
RSS: 109436232(CD40LG)
PALE: 102885468(CD40LG)
LAV: 100659000(CD40LG)
TMU: 101354525
MDO: 100010217(CD40LG)
SHR: 100918070(CD40LG)
OAA: 100083615(CD40LG)
GGA: 395485(CD40LG)
MGP: 100546658(CD40LG)
CJO: 107312660(CD40LG)
APLA: 101789598(CD40LG)
ACYG: 106037482(CD40LG)
TGU: 100231712(CD40LG)
GFR: 102031951(CD40LG)
FAB: 101808143(CD40LG)
PHI: 102107724(CD40LG)
PMAJ: 107203830(CD40LG)
CCW: 104691326(CD40LG)
FPG: 101911204(CD40LG)
FCH: 102059509(CD40LG)
CLV: 102086646(CD40LG)
EGZ: 104130245(CD40LG)
AAM: 106484755(CD40LG) 106492266
ASN: 102381504(CD40LG)
AMJ: 102575281(CD40LG)
PSS: 102447555(CD40LG)
CMY: 102945133(CD40LG)
ACS: 100556739(cd40lg)
PVT: 110088171(CD40LG)
PBI: 103063026(CD40LG)
GJA: 107121162(CD40LG) 107125310
XLA: 108698921(cd40lg.L) 108700557(cd40lg.S)
XTR: 100489038(cd40lg)
NPR: 108785871(CD40LG)
DRE: 793819(cd40lg)
CCAR: 109049094
IPU: 108268440(cd40lg)
SASA: 100286596(cd40l) 106604808
ELS: 105028611
SFM: 108922988 108928895(cd40lg)
LCM: 102357754(CD40LG)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1280226
  Authors
Graf D, Korthauer U, Mages HW, Senger G, Kroczek RA
  Title
Cloning of TRAP, a ligand for CD40 on human T cells.
  Journal
Eur J Immunol 22:3191-4 (1992)
DOI:10.1002/eji.1830221226
  Sequence
[hsa:959]
Reference
  Authors
Furman MI, Krueger LA, Linden MD, Barnard MR, Frelinger AL 3rd, Michelson AD
  Title
Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization.
  Journal
J Am Coll Cardiol 43:2319-25 (2004)
DOI:10.1016/j.jacc.2003.12.055
  Sequence
[hsa:959]

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