KEGG   ORTHOLOGY: K03231Help
Entry
K03231                      KO                                     

Name
EEF1A
Definition
elongation factor 1-alpha
Pathway
ko03013  RNA transport
ko05134  Legionellosis
ko05140  Leishmaniasis
Disease
H00606  Early infantile epileptic encephalopathy
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    K03231  EEF1A; elongation factor 1-alpha
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    K03231  EEF1A; elongation factor 1-alpha
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K03231  EEF1A; elongation factor 1-alpha
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K03231  EEF1A; elongation factor 1-alpha
   03016 Transfer RNA biogenesis
    K03231  EEF1A; elongation factor 1-alpha
   03012 Translation factors
    K03231  EEF1A; elongation factor 1-alpha
   04131 Membrane trafficking
    K03231  EEF1A; elongation factor 1-alpha
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03231  EEF1A; elongation factor 1-alpha
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Trans-acting binding proteins
     K03231  EEF1A; elongation factor 1-alpha
Transfer RNA biogenesis [BR:ko03016]
 Eukaryotic Type
  tRNA transport factors
   tRNA export factors
    K03231  EEF1A; elongation factor 1-alpha
Translation factors [BR:ko03012]
 Eukaryotic Type
  Elongation factors
   K03231  EEF1A; elongation factor 1-alpha
Membrane trafficking [BR:ko04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Other CMA associated proteins
    K03231  EEF1A; elongation factor 1-alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K03231  EEF1A; elongation factor 1-alpha
BRITE hierarchy
Other DBs
GO: 0003746
Genes
HSA: 1915(EEF1A1) 1917(EEF1A2)
PTR: 458406(EEF1A2) 494136(EEF1A1) 739210
PPS: 100978974(EEF1A1) 100985369(EEF1A2) 106634304
GGO: 101136757 101140395(EEF1A2) 101142679 101143481(EEF1A1) 109027324
PON: 100173928(EEF1A1) 100436751(EEF1A2) 100455760
NLE: 100583632(EEF1A1) 100586879 100588694(EEF1A2) 100605791 101175884 105738109 105740746
MCC: 100425937 696946(EEF1A2) 716010(EEF1A1)
MCF: 101864856(EEF1A2) 101925273(EEF1A1) 102122647(EEF1A1P5) 102123050 107126586
CSAB: 103242670(EEF1A2) 103243896(EEF1A1) 103248927
RRO: 104653877 104657006 104660179 104663847(EEF1A2) 104665804 104668174 104669279(EEF1A1) 104675330
RBB: 108529199(EEF1A1) 108535300(EEF1A2) 108538073 108541857
CJC: 100397123(EEF1A2) 100415334(EEF1A1) 100894850
MMU: 13627(Eef1a1) 13628(Eef1a2)
MCAL: 110302634(Eef1a1) 110307812(Eef1a2)
MPAH: 110318163(Eef1a2) 110328162(Eef1a1)
RNO: 171361(Eef1a1) 24799(Eef1a2)
CGE: 100689276(Eef1a1) 100760295(Eef1a2) 100770366
NGI: 103742257(Eef1a2) 103744356(Eef1a1)
HGL: 101698880 101719918(Eef1a1) 101720731(Eef1a2) 101726698
CCAN: 109692844(Eef1a2) 109701220(Eef1a1)
OCU: 100008677(EEF1A2) 100009189(EEF1A1)
CFA: 102155289 403506(EEF1A1) 612521(EEF1A2)
AML: 100469825(EEF1A1) 100471885(EEF1A2)
UAH: 113258809(EEF1A2) 113261115(EEF1A1) 113268611
FCA: 101083959 101100798(EEF1A2) 109502152 493922(EEF1A1)
PTG: 102952660(EEF1A1) 102956206(EEF1A2) 102959764 102966460
BTA: 282220(EEF1A1) 515233(EEF1A2)
BOM: 102282161(EEF1A2) 102283704(EEF1A1) 106701306
BIU: 109563706(EEF1A1) 109567253(EEF1A2)
CHX: 100860780(EEF1A1) 102170358 102170440(EEF1A2) 102176586
SSC: 110257403(EEF1A2) 574059(EEF1A1)
CFR: 102504723 102520234 102522434(EEF1A2) 102523342(EEF1A1)
CDK: 105099805 105103422(EEF1A2)
BACU: 103006701(EEF1A2) 103008671(EEF1A1) 103017593
LVE: 103069253 103083682(EEF1A1) 103084801(EEF1A2) 103087561
OOR: 101273989(EEF1A2) 101288902(EEF1A1) 101290163
DLE: 111178043 111179231 111183237(EEF1A1) 111186756(EEF1A2)
ECB: 100009682(EEF1A1) 100060464(EEF1A2)
EAI: 106824031 106827077(EEF1A1) 106827486 106836315(EEF1A2)
MYD: 102753217 102764966(EEF1A1) 102772510(EEF1A2) 102772711(NXNL2)
MNA: 107529510(EEF1A2) 107531623(EEF1A1) 107539198 107542480
HAI: 109379245 109380118(EEF1A2)
RSS: 109459178(EEF1A2)
DRO: 112303898(EEF1A2) 112319314(EEF1A1)
PALE: 102882869(EEF1A1) 102895186(EEF1A2) 102897478
MDO: 100011677 100016447(EEF1A1)
SHR: 100919601(EEF1A1) 100927986(EEF1A2)
PCW: 110195148 110205202(EEF1A2) 110217677(EEF1A1)
OAA: 100073607(EEF1A2) 100073896(EEF1A1)
GGA: 373963(EEF1A1) 419244(EEF1A2)
MGP: 100549103(EEF1A1) 100549386(EEF1A2)
CJO: 107312043(EEF1A1) 107323021(EEF1A2)
NMEL: 110396939(EEF1A1) 110408419(EEF1A2)
APLA: 101794346(EEF1A1) 101795161(EEF1A2)
ACYG: 106030364(EEF1A1) 106040851(EEF1A2)
TGU: 100223995(EEF1A1) 100231502(EEF1A2)
LSR: 110468956(EEF1A2) 110483698(EEF1A1)
SCAN: 103818713(EEF1A2) 103819723(EEF1A1)
GFR: 102034512(EEF1A1) 102045352(EEF1A2)
FAB: 101807688(EEF1A1) 101815673(EEF1A2)
PHI: 102111321(EEF1A1) 102111454(EEF1A2)
PMAJ: 107201487(EEF1A1) 107213396(EEF1A2)
CCAE: 111925807(EEF1A1) 111938093(EEF1A2)
CCW: 104687662(EEF1A2) 104692977(EEF1A1)
ETL: 114056408(EEF1A2) 114057636(EEF1A1)
FPG: 101919431(EEF1A2) 101920721(EEF1A1)
FCH: 102046963(EEF1A2) 102059553(EEF1A1)
CLV: 102084785(EEF1A1) 102088967(EEF1A2)
EGZ: 104128298(EEF1A1) 104130625(EEF1A2)
NNI: 104020040(EEF1A2) 104021985(EEF1A1)
ACUN: 113477759(EEF1A1) 113487404(EEF1A2)
PADL: 103919320(EEF1A2) 103924600(EEF1A1)
AAM: 106482530(EEF1A2) 106492499(EEF1A1)
ASN: 102370149 102375530(EEF1A2) 102384014 102387838(EEF1A1)
AMJ: 102558264(EEF1A2) 102560544 102566461 102567085(EEF1A1)
PSS: 102446534(EEF1A1) 102448670(EEF1A2) 102449205 102462452
ACS: 100561171(eef1a2) 100566578(eef1a1)
PVT: 110075016(EEF1A1) 110082523 110087587(EEF1A2)
PBI: 103059329(EEF1A1) 103060905(EEF1A2) 103065730
GJA: 107109946 107123190(EEF1A1)
XLA: 100036877 108695448 108702039 108704161 108705934 379289(eef1a-o1) 380550(eef1a2.S) 386604(eef1a1.L) 397889(42sp50.L) 397890(eef1a1o.L) 494720
XTR: 101734345 394920(eef1a1o) 496898(eef1a2) 496924(42Sp50) 549446(eef1a1)
DRE: 100004503(eef1a1b) 30516(eef1a1l1) 336334(eef1a1a) 436644(eef1a2) 664756(eef1a1l2)
SPU: 548620
APLC: 110978286
SKO: 100303511(EEF1A1)
DME: Dmel_CG1873(eEF1alpha2) Dmel_CG8280(eEF1alpha1)
DSI: Dsimw501_GD10821(Dsim_GD10821) Dsimw501_GD21598(Dsim_GD21598)
AME: 408385(Ef-1a-f1) 544670(EF1a-F2)
NVI: 100114226(EF-1a) 100114989
MDL: 103571135
TCA: 655495(Efa1) 658093
BMOR: 101743635 693059(EF1a)
DNX: 107163217
AGS: 114122129
BTAB: 109044237
CLEC: 106664506
ZNE: 110832006
CEL: CELE_F31E3.5(eef-1A.1) CELE_R03G5.1(eef-1A.2)
CBR: CBG16491(Cbr-eft-3.1) CBG16828 CBG24566(Cbr-eft-3.2)
TSP: Tsp_06754
PCAN: 112562047
OBI: 106878290
LAK: 106170554
SHX: MS3_08479
EGL: EGR_02642
EPA: 110242201
ADF: 107334639
PDAM: 113682290
SPIS: 111329426
HMG: 100206683(EF-1-alpha)
LJA: Lj0g3v0069139.1(Lj0g3v0069139.1) Lj0g3v0069149.1(Lj0g3v0069149.1) Lj0g3v0093839.1(Lj0g3v0093839.1) Lj1g3v3690420.1(Lj1g3v3690420.1) Lj2g3v0237250.1(Lj2g3v0237250.1) Lj5g3v1699430.1(Lj5g3v1699430.1)
SLY: 101244084 101264700 544055(LeEF-1)
DOSA: Os03t0177400-01(Os03g0177400) Os03t0177500-01(Os03g0177500) Os03t0177900-01(Os03g0177900) Os03t0178000-01(Os03g0178000)
ATS: 109746301(LOC109746301) 109746311(LOC109746311) 109756175(LOC109756175) 109756176(LOC109756176) 109758469(LOC109758469) 109759116(LOC109759116) 109759403(LOC109759403) 109768150(LOC109768150) 109783821(LOC109783821)
ZMA: 100037748(elfa2) 100284707 100286309(elf*-uaz7c01f12) 103630200 103631478 103635497 103635498 109939177 542555(elfa5) 542581(EF1-A) 542620(elfa3)
OLU: OSTLU_27060(EF1A1) OSTLU_27198(EF1A3) OSTLU_29711(EF1A2)
MIS: MICPUN_91047(TEF1.1) MICPUN_91112(TEF1.2)
APRO: F751_6279
SCE: YBR118W(TEF2) YPR080W(TEF1)
ERC: Ecym_3450
KMX: KLMA_80309(TEF)
NCS: NCAS_0A11260(NCAS0A11260) NCAS_0I01000(NCAS0I01000)
NDI: NDAI_0A05030(NDAI0A05030) NDAI_0A08020(NDAI0A08020)
TPF: TPHA_0A02400(TPHA0A02400) TPHA_0A03470(TPHA0A03470)
TBL: TBLA_0C02160(TBLA0C02160) TBLA_0F03090(TBLA0F03090)
TDL: TDEL_0C05190(TDEL0C05190)
KAF: KAFR_0D02610(KAFR0D02610) KAFR_0H00800(KAFR0H00800)
PIC: PICST_65303(TEF1) PICST_77514(TEF3)
SLB: AWJ20_1248(TEF1)
NCR: NCU02003(tef-1)
NTE: NEUTE1DRAFT118521(NEUTE1DRAFT_118521)
MGR: MGG_03641
SSCK: SPSK_06026
FPU: FPSE_11980(EF1A)
TRE: TRIREDRAFT_46958(tef1a)
MAW: MAC_00964
MAJ: MAA_03797
CMT: CCM_00809
BFU: BCIN_09g05760(Bcef1a)
MBE: MBM_07351
ANI: AN4218.2
ANG: ANI_1_648164(An18g04840)
PBL: PAAG_11418(PAAG_02024)
ABE: ARB_05700
TVE: TRV_03702
PTE: PTT_08441
SPO: SPAC23A1.10(tef102) SPBC839.15c(ef1a-c) SPCC794.09c(ef1a-a)
CNE: CNM01300
CNB: CNBM1160
ABP: AGABI1DRAFT81562(AGABI1DRAFT_81562)
ABV: AGABI2DRAFT133083(AGABI2DRAFT_133083)
MGL: MGL_0087
DDI: DDB_G0269134(efaAI) DDB_G0269136(efaAII)
DFA: DFA_04473(efaAI)
EHI: EHI_011210(143.t00006) EHI_052400(403.t00006) EHI_102170(470.t00004)
PYO: PY17X_0004700 PY17X_0004800(PY00361) PY17X_1134800(PY02338) PY17X_1134900(PY00362)
PCB: PCHAS_113280(PC300997.00.0) PCHAS_113290(PC000339.00.0)
TAN: TA06720
TPV: TP01_0726
BBO: BBOV_IV010620(23.m06453) BBOV_IV010630(23.m06438)
CPV: cgd6_3990
SMIN: v1.2.014002.t1(symbB.v1.2.014002.t1) v1.2.019110.t1(symbB.v1.2.019110.t1) v1.2.022452.t1(symbB.v1.2.022452.t1) v1.2.023263.t1(symbB.v1.2.023263.t1) v1.2.023264.t1(symbB.v1.2.023264.t1) v1.2.023265.t1(symbB.v1.2.023265.t1) v1.2.023722.t1(symbB.v1.2.023722.t1) v1.2.023723.t1(symbB.v1.2.023723.t1) v1.2.036461.t1(symbB.v1.2.036461.t1) v1.2.038138.t1(symbB.v1.2.038138.t1) v1.2.038139.t1(symbB.v1.2.038139.t1)
SPAR: SPRG_10439
GTT: GUITHDRAFT_149923(hEFL-1) GUITHDRAFT_84077(sEF1A-1)
MJA: MJ_0324
MMP: MMP1370(aEF-1_alpha)
MMD: GYY_07680
MAE: Maeo_0782
MVO: Mvol_1020
MWO: MWSIV6_1444(tuf) MWSIV6_1577(Gtpbp1)
METE: tca_01022(tufA) tca_01141(tufB)
MST: Msp_1366(tuf)
METB: AW729_08695(tuf)
MSI: Msm_0898
MRU: mru_1805
MEB: Abm4_0358
MMIL: sm9_1853
MEYE: TL18_08695(tuf)
MOL: YLM1_1268
MCUB: MCBB_0261(tuf) MCBB_2002(Gtpbp1)
MKA: MK0247
GAC: GACE_1458
GAH: GAH_01035
TAC: Ta0444
TVO: TVG1107082(TVG1107082)
PTO: PTO0415
FAI: FAD_1649
CDIV: CPM_1398
MEAR: Mpt1_c00290(tuf1)
MARC: AR505_1454
ABI: Aboo_0073
PHO: PH1484(PH1484)
PAB: PAB0465(tuf)
PFU: PF1375
PFI: PFC_06100
PYN: PNA2_0068
PYS: Py04_1376
PYC: TQ32_09510(tuf)
TKO: TK0308
TON: TON_0752
TGA: TGAM_1054(tuf)
TSI: TSIB_1561
THE: GQS_01130
THA: TAM4_769
THM: CL1_1931
TLT: OCC_11839(tuf)
THS: TES1_0925
TNU: BD01_0933
TEU: TEU_10455(tuf)
TGY: X802_09045(tuf)
TPEP: A0127_02715(tuf)
TGG: A3K92_03565(tuf)
TCE: A3L02_08325(tuf)
TBS: A3L01_04560(tuf)
THH: CDI07_04440(tuf)
TSL: A3L11_08645(tuf)
TTD: A3L14_06480(tuf)
TPRF: A3L09_04685(tuf)
TRL: A3L10_02050(tuf)
TPAF: A3L08_07380(tuf)
THY: A3L12_07865(tuf)
PPAC: PAP_02755(tuf)
MAC: MA_1256(ef1A)
MBAR: MSBR2_1500
MBAK: MSBR3_1420
MMA: MM_2264
MMAC: MSMAC_2013
METM: MSMTP_0836
MTHE: MSTHC_2298
MTHR: MSTHT_1008
MHOR: MSHOH_1023
MFZ: AOB57_011420(tuf)
MBU: Mbur_1170
MMET: MCMEM_1638
MMH: Mmah_0538
MPY: Mpsy_1015
MTP: Mthe_0821
MCJ: MCON_1649(tuf)
MHI: Mhar_0302
MHU: Mhun_1592
MLA: Mlab_1441
MBG: BN140_1062(tuf)
MPI: Mpet_0694
MBN: Mboo_0699
MPL: Mpal_1553
MPD: MCP_1225(tuf) MCP_1891
MEZ: Mtc_2153(tuf-2) Mtc_2220
RCI: LRC365(tuf-1) RCIX2739
HAL: VNG_1676G(gbp2) VNG_2649G(eef1a)
HSL: OE_3371F OE_4721R(tef1a1)
HHB: Hhub_1260(tef1a) Hhub_3186
HMA: rrnAC1619(gbp2) rrnAC2406(eef1a)
HHI: HAH_2161(gbp1) HAH_2841(tef1A)
NPH: NP_0304A(tef1a) NP_1740A
NMO: Nmlp_2296 Nmlp_3831(tef1a)
HWA: HQ_2800A HQ_3385A(tef1a)
HWC: Hqrw_3172 Hqrw_3911(tef1a)
HVO: HVO_0359(tef1a1) HVO_2575
HME: HFX_0346(tef1A) HFX_2417(tef1A) HFX_2601(gbp)
SRUB: C2R22_01500(tuf) C2R22_02010(tuf)
NMG: Nmag_0200 Nmag_2516(tef1a1) Nmag_3261(tef1a2)
NAC: AQV86_05545(tuf)
APE: APE_1844(tuf)
ACJ: ACAM_1157(tuf)
SMR: Smar_0810
IHO: Igni_1150
IIS: EYM_03600(tuf)
DKA: DKAM_1368
TAG: Tagg_1399
IAG: Igag_1238
HBU: Hbut_1581
STO: STK_02690(tuf) STK_05570
SSO: SSO0216(tuF-1) SSO2429(tuF-2)
SSOA: SULA_0225 SULA_1236(tuf)
SSOL: SULB_0226 SULB_1237(tuf)
SSOF: SULC_0225 SULC_1235(tuf)
CMA: Cmaq_1745
TTN: TTX_0013(aef-1a) TTX_1549(cgp-1)
VDI: Vdis_0704
VMO: VMUT_1551
ASC: ASAC_1183
ACIA: SE86_07075(tuf)
NMR: Nmar_1034
NID: NPIRD3C_1122(tuf)
NIN: NADRNF5_0896(tuf)
NCT: NMSP_0598(tuf_1)
NGA: Ngar_c02920(tuf)
NVN: NVIE_014400(ef1a)
NEV: NTE_02856
TAA: NMY3_02943(tufB)
NFN: NFRAN_0421(tuf)
NCV: NCAV_0794(tuf)
NBV: T478_0861(tuf)
TAH: SU86_001045(tuf)
NDV: NDEV_1054(tuf)
NEQ: NEQ082
NAA: Nps_00095(tuf)
MARH: Mia14_0223
BARC: AOA65_0276(tuf)
BARB: AOA66_1001(tuf)
LOKI: Lokiarch_28570(tuf_2)
VG: 20041593(JO84_gp355)
 » show all
TaxonomyVtaxonomyKoalaUniProt
Reference
  Authors
Grosshans H, Hurt E, Simos G
  Title
An aminoacylation-dependent nuclear tRNA export pathway in yeast.
  Journal
Genes Dev 14:830-40 (2000)
DOI:10.1101/gad.14.7.830
  Sequence
[sce:YBR118W] [sce:YPR080W]
Reference
  Authors
Maruyama T, Nara K, Yoshikawa H, Suzuki N
  Title
Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells.
  Journal
Clin Exp Immunol 147:164-75 (2007)
DOI:10.1111/j.1365-2249.2006.03249.x
  Sequence
[hsa:1915]

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