KEGG   ORTHOLOGY: K03388
Entry
K03388                      KO                                     
Symbol
hdrA2
Name
heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
Pathway
map00680  Methane metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Reaction
R11928  CoB,CoM,ferredoxin:coenzyme F420 oxidoreductase
R11931  CoB,CoM:ferredoxin oxidoreductase
R11943  CoB,CoM,ferredoxin:H2 oxidoreductase
R11944  coenzyme B,coenzyme M,ferredoxin:formate oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K03388  hdrA2; heterodisulfide reductase subunit A2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
   1.8.98  With other, known, physiological acceptors
    1.8.98.4  coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
Other DBs
COG: COG1148
Genes
TMB: Thimo_0253
HHC: M911_11230
EBS: ECTOBSL9_0285
TGR: Tgr7_2214
TKM: TK90_0634
TNI: TVNIR_3247(hdrA_[H])
TVR: TVD_10640
APRS: BI364_13805
AAEO: BJI67_04070
AFY: BW247_09925
CBX: Cenrod_2147(hdrA)
SPLB: SFPGR_29450(hdrA)
SNIV: SFSGTM_27290(hdrA)
SLAC: SKTS_06230(hdrA-2)
HDN: Hden_0691
BLAG: BLTE_14930(hdrA-2)
RHC: RGUI_1281
RAP: RHOA_4364(hdrA)
AFR: AFE_2553
ATX: GCD22_03148(hdrA) GCD22_03279(hdrA)
GSU: GSU0090(hdrA)
GSK: KN400_0065(hdrA)
GME: Gmet_2084(bamE) Gmet_3426(hdrA)
GEO: Geob_0215(bamE-1) Geob_0231(bamE-2) Geob_3723(hdrA)
GLO: Glov_0864
TAMM: GEAMG1_2373(hdrA)
GBM: Gbem_0030(hdrA) Gbem_1447(bamE)
DDS: Ddes_2100
DTR: RSDT_0567(hdrA)
DMA: DMR_01920(hdrA) DMR_22120
DGG: DGI_1050(hdrA)
DHY: DESAM_21330(hdrA)
DPI: BN4_11860(hdrA)
PSEF: PSDVSF_30220(hdrA)
PNW: SYK_07320
DVU: DVU_2402(hdrA)
DVL: Dvul_0828
DVM: DvMF_0324
CLIH: KPS_000425
THEW: TDMWS_00850(hdrA)
DPS: DP1010
DOL: Dole_1159
DAT: HRM2_11710(hdrA1) HRM2_11850(hdrA2) HRM2_14330(hdrA3) HRM2_14340(hdrA3') HRM2_22100(hdrL1) HRM2_22720(hdrL2) HRM2_22750(hdrA4) HRM2_30780 HRM2_30890(hdrL3)
DTO: TOL2_C03750(bamE1) TOL2_C08890 TOL2_C09040(hdlA1) TOL2_C11590(hdlA2) TOL2_C11630(hdlA3?) TOL2_C17870(hdlA4) TOL2_C17900(hdlA5) TOL2_C24180(hdlA6) TOL2_C25730(hdlA7) TOL2_C28760(hdlA8) TOL2_C28830(hdlA9) TOL2_C33300(hdlA10) TOL2_C41400(bamE2) TOL2_C43540(bamE3)
DML: Dmul_02770(hdrA1) Dmul_24500(bamE) Dmul_28860(hdrA2)
CTHI: THC_1756
ADE: Adeh_4164
BTS: Btus_2496
RCH: RUM_10980
SMAN: C12CBH8_20550(hdrA)
SWO: Swol_0397
SALQ: SYNTR_0264
SGY: Sgly_1900
PTH: PTH_1410(HdrA)
HMO: HM1_2008(hdrA)
SAY: TPY_3529(hdrA)
BPRO: PMF13cell1_01672(ndhI_2)
BCOC: BLCOC_07540(napF)
MTHZ: MOTHA_c04660(rsxB1) MOTHA_c08510(ndhI3) MOTHA_c12570(sfrB1) MOTHA_c15280(mnmC2)
STED: SPTER_13760(mnmC)
AFO: Afer_0966
PPSU: NO713_02684(hdrA)
DFO: Dform_00893(hdrA) Dform_00920(hdrA) Dform_00941(hdrA)
TRO: trd_0153
OTE: Oter_3677
MSIL: METEAL_37400(hdrA)
APS: CFPG_240
AFD: Alfi_2101
ASH: AL1_26630
BACC: BRDCF_p1060 BRDCF_p823(hdrA)
ANF: AQPE_4789
MBAS: ALGA_3491
CTE: CT1246(hdrA-2)
CPC: Cpar_0949
CCH: Cag_1029
CLI: Clim_1200
PVI: Cvib_0843
PLT: Plut_1109
PPH: Ppha_1306
CTS: Ctha_0136
AAE: aq_395(hdrA)
HTH: HTH_1881(hdrA)
TAL: Thal_1346
CABY: Cabys_1917
DTP: JZK55_01240(hdrA)
BANA: BARAN1_0338(hdrA)
SCHV: BRCON_0020
MMP: MMP0825(hdrA) MMP1697(hdrA)
MMD: GYY_04785
MMAK: MMKA1_09100(hdrA) MMKA1_19310(hdrA)
MMAO: MMOS7_08880(hdrA) MMOS7_18120(hdrA)
MMAD: MMJJ_01720(hdrA) MMJJ_11320(hdrA2)
MTH: MTH_1381
MMG: MTBMA_c17680(hdrA)
MWO: MWSIV6_1762(hdrA)
MTEE: MTTB_15540
METC: MTCT_1255
METE: tca_01335(rsxB_2)
MST: Msp_1476(hdrA1)
MRU: mru_0117(hdrA)
MSI: Msm_1336
MEB: Abm4_1691(hdrA2)
MMIL: sm9_2251(hdrA2)
MEYE: TL18_00375
MOL: YLM1_1554
METH: MBMB1_1958(hdrA)
MFC: BRM9_2298(hdrA2)
MFI: DSM1535_1232(hdrA)
MCUB: MCBB_2243(hdrA3)
MFV: Mfer_0184
MKA: MK0249(hdrA_1) MK0265(hdrA_2)
MBAR: MSBR2_0910
MBAK: MSBR3_0798
MAC: MA_2868(hdrA)
MMA: MM_0056
METM: MSMTP_1469
MTHR: MSTHT_0375
MTHE: MSTHC_0346
MBU: Mbur_0552(hdrA)
MMET: MCMEM_1365
MMH: Mmah_0955
MMAV: RE476_05120(hdrA2)
MSEB: RE474_01380(hdrA2) RE474_01410
MEHF: MmiHf6_05690(mnmC)
MEES: MmiEs2_04330(ndhI)
MTP: Mthe_1576
MCJ: MCON_3279(hdrA)
MHI: Mhar_0607
MBG: BN140_0752(hdrA1) BN140_1728(hdrA3)
MEMA: MMAB1_0971(hdrA) MMAB1_2223(hdrA)
MPD: MCP_1576(hdrA-1) MCP_2768(hdrA-2)
MEZ: Mtc_2473(hdrA-2)
RCI: RCIX596(hdrA-2) RRC258(hdrA-3)
HDF: AArcSl_1855(hdrA)
HAAA: AArcCO_0216(hdrA)
MEAR: Mpt1_c10580(hdrA)
MARC: AR505_1479
STO: STK_18730
SSO: SSO1131(hdrA)
SOL: Ssol_2101
SSOA: SULA_2132
SSOL: SULB_2133
SSOF: SULC_2131
SCAS: SACC_10190
SAI: Saci_0328(hdrA)
SID: M164_1089
SII: LD85_1217
SIH: SiH_1060
SIR: SiRe_0973
SIC: SiL_0979
MSE: Msed_1545
MEMJ: MJ1HA_1762
MCN: Mcup_0686
AHO: Ahos_1694
ACIH: HS5_01370
CSTY: KN1_04080
STEP: IC006_0777
SAHS: HS7_01170
BARC: AOA65_1112(hdrA_1) AOA65_1402(hdrA_3) AOA65_1719(hdlA_2) AOA65_1720(sudA_4) AOA65_1995(hdrA_4)
BARB: AOA66_0155(hdrA_1) AOA66_1510(hdrA_2) AOA66_1512(hdlA_2) AOA66_1513(hdrA_3) AOA66_1526(hdrA_4)
LOKI: Lokiarch_01240(hdrA_2) Lokiarch_08680(hdrA_4) Lokiarch_10040(hdlA_3) Lokiarch_17940(hdlA_5) Lokiarch_23600(hdrA_8) Lokiarch_25880(hdrA_9) Lokiarch_28050(hdrA_10) Lokiarch_41160(hdrA_15) Lokiarch_49330(hdrA_16)
PSYT: DSAG12_01136(hdrA_1) DSAG12_01147(hdrA_2) DSAG12_02805(hdrA_4) DSAG12_03220(hdrA_5) DSAG12_03721(hdrA_6) DSAG12_03723(hdlA_4) DSAG12_03724(hdrA_7)
 » show all
Reference
PMID:2121478
  Authors
Hedderich R, Berkessel A, Thauer RK
  Title
Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).
  Journal
Eur J Biochem 193:255-61 (1990)
DOI:10.1111/j.1432-1033.1990.tb19331.x
  Sequence
Reference
PMID:8119281
  Authors
Setzke E, Hedderich R, Heiden S, Thauer RK
  Title
H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties.
  Journal
Eur J Biochem 220:139-48 (1994)
DOI:10.1111/j.1432-1033.1994.tb18608.x
  Sequence
Reference
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
  Sequence
[apo:Arcpr_1555] [afu:AF_1377]

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