KEGG   ORTHOLOGY: K03456Help
Entry
K03456                      KO                                     

Name
PPP2R1
Definition
serine/threonine-protein phosphatase 2A regulatory subunit A
Pathway
ko03015  mRNA surveillance pathway
ko04071  Sphingolipid signaling pathway
ko04111  Cell cycle - yeast
ko04113  Meiosis - yeast
ko04114  Oocyte meiosis
ko04151  PI3K-Akt signaling pathway
ko04152  AMPK signaling pathway
ko04261  Adrenergic signaling in cardiomyocytes
ko04350  TGF-beta signaling pathway
ko04390  Hippo signaling pathway
ko04391  Hippo signaling pathway - fly
ko04530  Tight junction
ko04728  Dopaminergic synapse
ko04730  Long-term depression
ko05142  Chagas disease (American trypanosomiasis)
ko05160  Hepatitis C
ko05165  Human papillomavirus infection
Disease
H00773  Autosomal dominant mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04390 Hippo signaling pathway
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04391 Hippo signaling pathway - fly
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04071 Sphingolipid signaling pathway
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04151 PI3K-Akt signaling pathway
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04152 AMPK signaling pathway
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
 09140 Cellular Processes
  09143 Cell growth and death
   04111 Cell cycle - yeast
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04113 Meiosis - yeast
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04114 Oocyte meiosis
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
 09150 Organismal Systems
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
  09156 Nervous system
   04728 Dopaminergic synapse
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   04730 Long-term depression
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
   05165 Human papillomavirus infection
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
  09174 Infectious disease: parasitic
   05142 Chagas disease (American trypanosomiasis)
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Regulatory subunits
     K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   Other centromeric chromatin formation proteins
    PP2A (protein phosphatase 2A)
     K03456  PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
BRITE hierarchy
Other DBs
GO: 0008601
Genes
HSA: 5518(PPP2R1A) 5519(PPP2R1B)
PTR: 466778(PPP2R1B) 468983(PPP2R1A)
PPS: 100991308(PPP2R1B) 100995920(PPP2R1A)
GGO: 101142397(PPP2R1A) 101145146(PPP2R1B)
PON: 100173260(PPP2R1A) 100437928(PPP2R1B)
NLE: 100598916(PPP2R1A) 100605248(PPP2R1B)
MCC: 710387(PPP2R1B) 719929(PPP2R1A)
MCF: 101865477(PPP2R1B) 101867273(PPP2R1A)
CSAB: 103235167(PPP2R1A) 103248442(PPP2R1B)
RRO: 104672685(PPP2R1A) 104677337(PPP2R1B)
RBB: 108523953(PPP2R1A) 108536465(PPP2R1B)
CJC: 100408674(PPP2R1B) 100413664(PPP2R1A)
SBQ: 101033118(PPP2R1B) 101034311(PPP2R1A)
MMU: 51792(Ppp2r1a) 73699(Ppp2r1b)
MCAL: 110302129(Ppp2r1b) 110312643(Ppp2r1a)
MPAH: 110328279(Ppp2r1b) 110337932(Ppp2r1a)
RNO: 117281(Ppp2r1a) 315648(Ppp2r1b)
CGE: 100771272(Ppp2r1b) 100773447(Ppp2r1a)
NGI: 103733889(Ppp2r1b) 103745507(Ppp2r1a)
HGL: 101703470(Ppp2r1a) 101722244(Ppp2r1b)
CCAN: 109687790(Ppp2r1b) 109699358(Ppp2r1a)
OCU: 100355092(PPP2R1A) 100355758(PPP2R1B)
TUP: 102477439(PPP2R1B) 102480902(PPP2R1A)
CFA: 479444(PPP2R1B) 484335(PPP2R1A)
VVP: 112925972(PPP2R1B) 112931417(PPP2R1A)
AML: 100482129(PPP2R1A) 100482604(PPP2R1B)
UMR: 103657330(PPP2R1A) 103662531(PPP2R1B)
UAH: 113247257(PPP2R1A) 113260072(PPP2R1B)
ORO: 101362885(PPP2R1B) 101385466(PPP2R1A)
FCA: 101081075(PPP2R1B) 101083726(PPP2R1A)
PTG: 102951141(PPP2R1A) 102961543(PPP2R1B)
PPAD: 109252915(PPP2R1A) 109278670(PPP2R1B)
AJU: 106973000(PPP2R1A) 106984444(PPP2R1B)
BTA: 100138150(PPP2R1B) 535321(PPP2R1A) 616695
BIU: 109554937 109569423(PPP2R1B) 109572651(PPP2R1A)
BBUB: 102396397(PPP2R1A) 102409320(PPP2R1B) 102412869
CHX: 102170070(PPP2R1B) 102182533(PPP2R1A)
OAS: 101108511(PPP2R1B) 101115302(PPP2R1A)
SSC: 397088(PPP2R1A) 397470(PPP2R1B)
CFR: 102505057(PPP2R1B) 102509649(PPP2R1A)
CDK: 105092005(PPP2R1A) 105094015(PPP2R1B)
BACU: 103017366 103019457(PPP2R1B)
LVE: 103068746(PPP2R1B) 103082213
OOR: 101274740(PPP2R1A) 101275690(PPP2R1B)
DLE: 111168062(PPP2R1B) 111181079(PPP2R1A)
PCAD: 102992184(PPP2R1A) 102992659(PPP2R1B)
ECB: 100062627(PPP2R1A) 100070408(PPP2R1B)
EPZ: 103555607(PPP2R1B) 103564670(PPP2R1A)
EAI: 106822667(PPP2R1A) 106840324(PPP2R1B)
MYB: 102254517(PPP2R1B) 102261651 102262643(PPP2R1A)
MYD: 102758648(PPP2R1B) 102762854(PPP2R1A)
MNA: 107531299(PPP2R1B) 107540441(PPP2R1A)
HAI: 109377484(PPP2R1A) 109388695(PPP2R1B)
PALE: 102888699(PPP2R1A) 102894487(PPP2R1B)
RAY: 107500417(PPP2R1A) 107521184(PPP2R1B)
MJV: 108405702(PPP2R1A) 108409551(PPP2R1B)
LAV: 100654486(PPP2R1A) 100663532(PPP2R1B)
MDO: 100026516(PPP2R1B) 100028805(PPP2R1A)
SHR: 100922551(PPP2R1B) 100927161
PCW: 110210692(PPP2R1B) 110219910(PPP2R1A)
OAA: 100075412(PPP2R1A) 100090340(PPP2R1B)
CJO: 107307645
TGU: 100217782(PPP2R1A)
LSR: 110481563(PPP2R1A) 110483036
PHI: 102099118(PPP2R1A)
ETL: 114072490(PPP2R1A)
FPG: 101912140(PPP2R1A)
FCH: 102056197(PPP2R1A)
CLV: 102088592
NNI: 104010292
ASN: 102376404(PPP2R1A)
AMJ: 102571411(PPP2R1A)
PSS: 102446420(PPP2R1A)
CMY: 102937853
CPIC: 101946593(PPP2R1A)
ACS: 100567091(ppp2r1a)
PVT: 110086512(PPP2R1A)
PBI: 103058492(PPP2R1A)
PMUR: 107295075(PPP2R1A)
TSR: 106546744(PPP2R1A)
PMUA: 114603487(PPP2R1A)
GJA: 107124393(PPP2R1A)
XLA: 108705486 379827(ppp2r1a.L) 380100(ppp2r1b.S) 394339(ppp2r1a.S) 398563
XTR: 101731355 395042(ppp2r1a) 448463(pdgfb)
NPR: 108793093(PPP2R1B) 108798779
DRE: 406685(ppp2r1ba) 449548(ppp2r1bb)
IPU: 108260120(PPP2R1B) 108277698
TRU: 101075238
LCO: 104918016
NCC: 104965971
MZE: 101483438(ppp2r1b)
ONL: 100695673(ppp2r1b)
OLA: 101167061
XMA: 102218705(ppp2r1b)
XCO: 114161548(ppp2r1b)
PRET: 103474595(ppp2r1b)
CVG: 107086379(ppp2r1b)
NFU: 107380329
KMR: 108243526
ALIM: 106515438(ppp2r1b)
AOCE: 111587249
CSEM: 103378498
POV: 109630286
LCF: 108895267
SDU: 111228032(ppp2r1b)
SLAL: 111655990(ppp2r1b)
HCQ: 109526371
BPEC: 110154099
MALB: 109960236(ppp2r1b)
SASA: 106612458(2AAB)
ELS: 105011486
PKI: 111844798(ppp2r1b)
LCM: 102361089(PPP2R1A) 102365784(PPP2R1B)
CMK: 103187684(ppp2r1a)
CIN: 100187349
SPU: 583227
APLC: 110982061
SKO: 100369726(PPP2R1A)
DME: Dmel_CG17291(Pp2A-29B)
DER: 6543494
DSI: Dsimw501_GD23530(Dsim_GD23530)
DYA: Dyak_GE18761(Dyak_Pp2A-29B)
DPE: 6589072
DMN: 108163364
DWI: 6644289
DAZ: 108610971
DNV: 108649352
DHE: 111598949
MDE: 101897881
LCQ: 111686206
AAG: 5568618
AME: 726088
BIM: 100746409
BTER: 100650625
CCAL: 108631518
OBB: 114873065
SOC: 105200773
MPHA: 105836934
AEC: 105150624
ACEP: 105625593
PBAR: 105432584
VEM: 105559868
HST: 105185991
DQU: 106741697
CFO: 105257564
LHU: 105670073
PGC: 109852499
OBO: 105278543
PCF: 106793213
NVI: 100117468
CSOL: 105364740
MDL: 103569520
TCA: 641602(Ppp2r1a) 656557
PMAC: 106717356
PRAP: 110998917
HAW: 110374283
TNL: 113494680
AGS: 114123094
BTAB: 109032342
ZNE: 110839728
FCD: 110842906
TUT: 107364564
DPTE: 113798380
CSCU: 111637255
PTEP: 107442215
CEL: CELE_F48E8.5(paa-1)
CBR: CBG05190(Cbr-paa-1)
BMY: Bm1_14145
TSP: Tsp_00897
PCAN: 112568262
CRG: 105343833
MYI: 110442272
OBI: 106881318
LAK: 106161609
EPA: 110251134
ADF: 107358396
AMIL: 114953904
PDAM: 113666488
SPIS: 111342447
DGT: 114524484
HMG: 100215656(ppp2r1a)
AQU: 100631486
ATH: AT1G13320(PP2AA3) AT1G25490(RCN1) AT3G25800(PP2AA2)
LJA: Lj2g3v0742070.1(Lj2g3v0742070.1) Lj2g3v0742070.2(Lj2g3v0742070.2) Lj2g3v0742070.3(Lj2g3v0742070.3) Lj2g3v1155670.1(Lj2g3v1155670.1) Lj5g3v2217170.1(Lj5g3v2217170.1)
CSV: 101222376
CMO: 103489266
MCHA: 111018768
OSA: 4346507
DOSA: Os09t0249700-01(Os09g0249700)
OBR: 102708461
ATS: 109746060(LOC109746060)
ZMA: 100283785(cl9687_1) 103638140 732740(pco067871)
DCT: 110094524
PEQ: 110038493
MIS: MICPUN_97654(PP2A1)
MPP: MICPUCDRAFT_30915(PP2A)
APRO: F751_2345
SCE: YAL016W(TPD3)
ERC: Ecym_2638
KMX: KLMA_20364(TPD3)
NCS: NCAS_0F01570(NCAS0F01570)
NDI: NDAI_0H02460(NDAI0H02460)
TPF: TPHA_0H02620(TPHA0H02620) TPHA_0L00520(TPHA0L00520)
TBL: TBLA_0E02270(TBLA0E02270)
TDL: TDEL_0H03620(TDEL0H03620)
KAF: KAFR_0D01240(KAFR0D01240)
CAL: CAALFM_C306910CA(TPD3)
SLB: AWJ20_4688(TPD3)
NCR: NCU00488
NTE: NEUTE1DRAFT117101(NEUTE1DRAFT_117101)
MGR: MGG_05671
SSCK: SPSK_07156
MAW: MAC_08344
MAJ: MAA_03580
CMT: CCM_07404
BFU: BCIN_10g05400(Bctpd3)
MBE: MBM_02149
ANI: AN4085.2
ANG: ANI_1_418164(An18g03290)
TVE: TRV_05536
PTE: PTT_10751
ZTR: MYCGRDRAFT_70921(MgPP2AregA)
SPO: SPAP8A3.09c(paa1)
CNE: CNM02110
CNB: CNBM1970
ABP: AGABI1DRAFT110479(AGABI1DRAFT_110479)
ABV: AGABI2DRAFT189621(AGABI2DRAFT_189621)
MGL: MGL_0095
MRT: MRET_1226
ECU: ECU09_1490(pp2-a)
DDI: DDB_G0283601(pppA)
DFA: DFA_03639(pppA)
EHI: EHI_010630(95.t00013) EHI_124530(42.t00015) EHI_124870(302.t00007)
TAN: TA08640
TPV: TP04_0474
BBO: BBOV_II001110(18.m06081)
SMIN: v1.2.031666.t1(symbB.v1.2.031666.t1) v1.2.031666.t2(symbB.v1.2.031666.t2)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2554323
  Authors
Walter G, Ferre F, Espiritu O, Carbone-Wiley A
  Title
Molecular cloning and sequence of cDNA encoding polyoma medium tumor antigen-associated 61-kDa protein.
  Journal
Proc Natl Acad Sci U S A 86:8669-72 (1989)
DOI:10.1073/pnas.86.22.8669
  Sequence
[hsa:5518]
Reference
PMID:9765152
  Authors
Wang SS, Esplin ED, Li JL, Huang L, Gazdar A, Minna J, Evans GA
  Title
Alterations of the PPP2R1B gene in human lung and colon cancer.
  Journal
Science 282:284-7 (1998)
DOI:10.1126/science.282.5387.284
  Sequence
[hsa:5519]

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