KEGG   ORTHOLOGY: K03506Help
Entry
K03506                      KO                                     

Name
POLE4
Definition
DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
Pathway
ko00230  Purine metabolism
ko00240  Pyrimidine metabolism
ko01100  Metabolic pathways
ko03030  DNA replication
ko03410  Base excision repair
ko03420  Nucleotide excision repair
ko05166  Human T-cell leukemia virus 1 infection
Module
M00263  DNA polymerase epsilon complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K03506  POLE4; DNA polymerase epsilon subunit 4
   00240 Pyrimidine metabolism
    K03506  POLE4; DNA polymerase epsilon subunit 4
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    K03506  POLE4; DNA polymerase epsilon subunit 4
   03410 Base excision repair
    K03506  POLE4; DNA polymerase epsilon subunit 4
   03420 Nucleotide excision repair
    K03506  POLE4; DNA polymerase epsilon subunit 4
 09160 Human Diseases
  09167 Infectious diseases
   05166 HTLV-I infection
    K03506  POLE4; DNA polymerase epsilon subunit 4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K03506  POLE4; DNA polymerase epsilon subunit 4
   03400 DNA repair and recombination proteins
    K03506  POLE4; DNA polymerase epsilon subunit 4
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   DNA polymerase
    M00263  DNA polymerase epsilon complex
     K03506  POLE4; DNA polymerase epsilon subunit 4
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     K03506  POLE4; DNA polymerase epsilon subunit 4
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    K03506  POLE4; DNA polymerase epsilon subunit 4
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      K03506  POLE4; DNA polymerase epsilon subunit 4
BRITE hierarchy
Other DBs
RN: R00375 R00376 R00377 R00378
GO: 0003887
Genes
HSA: 56655(POLE4)
PTR: 459343(POLE4)
PPS: 100982360(POLE4)
GGO: 101126230(POLE4)
PON: 100451783(POLE4)
NLE: 100593342(POLE4)
MCC: 710562(POLE4)
MCF: 101867407(POLE4)
CSAB: 103220011(POLE4)
RRO: 104674835(POLE4)
RBB: 108531691(POLE4)
CJC: 100414929(POLE4)
SBQ: 101045109(POLE4)
MMU: 66979(Pole4)
RNO: 362385(Pole4)
CGE: 103163165(Pole4)
NGI: 103733850(Pole4)
HGL: 101711731 101721926(Pole4)
CCAN: 109697835(Pole4)
OCU: 100358589(POLE4)
TUP: 102498485(POLE4)
CFA: 483096(POLE4)
AML: 100477978(POLE4)
UMR: 103663520(POLE4)
ORO: 101384323(POLE4)
FCA: 101089849(POLE4)
BTA: 613730(POLE4)
BOM: 102275662(POLE4)
PHD: 102344898
CHX: 102191340(POLE4)
OAS: 105609801
SSC: 100517646(POLE4)
CDK: 105085173(POLE4)
BACU: 103006795(POLE4)
LVE: 103078646(POLE4)
OOR: 101278492(POLE4)
ECB: 100068933(POLE4)
EAI: 106835131(POLE4)
MYB: 102246982(POLE4)
MYD: 102767991(POLE4)
HAI: 109371192(POLE4)
RSS: 109457426(POLE4)
PALE: 102896323(POLE4)
TMU: 101342043
MDO: 100032850(POLE4)
OAA: 100084266(POLE4)
GGA: 107055326(POLE4)
MGP: 104914653(POLE4)
CJO: 107325669(POLE4)
TGU: 100222316(POLE4)
FAB: 101819262(POLE4)
PHI: 102113459(POLE4)
PMAJ: 107215360(POLE4)
CLV: 102096962(POLE4)
AMJ: 102573996(POLE4)
PVT: 110072494(POLE4)
XLA: 779084(pole4.L)
XTR: 549359(pole4)
NPR: 108802028(POLE4)
DRE: 553610(pole4)
IPU: 108271212(pole4)
AMEX: 103045108(pole4)
TRU: 101067055(pole4)
LCO: 104930480(pole4)
NCC: 104959649(pole4)
MZE: 101474498(pole4)
OLA: 101162035(pole4)
XMA: 102231701(pole4)
PRET: 103463523(pole4)
NFU: 107373552(pole4)
CSEM: 103397641(pole4)
LCF: 108881386(pole4)
HCQ: 109532274(pole4)
BPEC: 110160062(pole4)
SASA: 100195891(dpoe4) 106613703(DPOE4)
ELS: 105011481(pole4)
SFM: 108921530(pole4)
LCM: 102366845(POLE4)
CMK: 103184515(pole4)
CIN: 100179904
SPU: 763808
APLC: 110985227
SKO: 100378559
DME: Dmel_CG11301(Mes4)
DSI: Dsimw501_GD11667(Dsim_GD11667)
MDE: 101890239
AAG: 5572871
AME: 725835
BIM: 100740208
BTER: 100651831
SOC: 105192811
AEC: 105146980
ACEP: 105627473
PBAR: 105423637
HST: 105189661
CFO: 105253129
LHU: 105671464
PGC: 109855377
NVI: 100114582
TCA: 660566
DPA: 109539603
NVL: 108565074
BMOR: 101736457
PMAC: 106721347
PRAP: 110993520
PXY: 105382516
API: 100166046
DNX: 107172296
ZNE: 110832709
CEL: CELE_Y53F4B.3(Y53F4B.3)
CRG: 105343270
MYI: 110454927
OBI: 106876082
LAK: 106181069
SHX: MS3_06842
EPA: 110254548
ADF: 107348451
AQU: 100632272
BRP: 103871543
BOE: 106311433
THJ: 104815749
DZI: 111286385
PPER: 18774921
PMUM: 103325121
PAVI: 110771159
OEU: 111381367
LSV: 111881072
SCE: YBR278W(DPB3) YJL065C(DLS1)
ERC: Ecym_6281
KMX: KLMA_50078(DPB3)
NCS: NCAS_0A09230(NCAS0A09230) NCAS_0B07510(NCAS0B07510)
NDI: NDAI_0B04830(NDAI0B04830) NDAI_0G05730(NDAI0G05730)
TPF: TPHA_0I01210(TPHA0I01210)
TBL: TBLA_0F01380(TBLA0F01380)
TDL: TDEL_0D01790(TDEL0D01790)
KAF: KAFR_0A01690(KAFR0A01690) KAFR_0A03690(KAFR0A03690)
PIC: PICST_30658(DPB3)
CAL: CAALFM_C103640CA(HFL1)
CAUR: QG37_07353
CNE: CNG03660
CNB: CNBG1090
ABP: AGABI1DRAFT113914(AGABI1DRAFT_113914)
ABV: AGABI2DRAFT193750(AGABI2DRAFT_193750)
MGL: MGL_1620
DFA: DFA_10079
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Shimizu K, Hashimoto K, Kirchner JM, Nakai W, Nishikawa H, Resnick MA, Sugino A
  Title
Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae.
  Journal
J Biol Chem 277:37422-9 (2002)
DOI:10.1074/jbc.M204476200
  Sequence
[sce:YBR278W]

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