Entry |
|
Symbol |
ALG8
|
Name |
|
Pathway |
|
Module |
M00055 | N-glycan precursor biosynthesis |
|
Reaction |
R06263 | dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase |
|
Disease |
H00118 | Congenital disorders of glycosylation type I |
H00545 | Polycystic liver disease |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00510 N-Glycan biosynthesis
K03849 ALG8; alpha-1,3-glucosyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases
K03849 ALG8; alpha-1,3-glucosyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.265 dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase
K03849 ALG8; alpha-1,3-glucosyltransferase
Glycosyltransferases [BR:ko01003]
N-Glycan biosynthesis
Dol-linked oligosaccharide
K03849 ALG8; alpha-1,3-glucosyltransferase
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Stagljar I, te Heesen S, Aebi M |
Title |
New phenotype of mutations deficient in glucosylation of the lipid-linked oligosaccharide: cloning of the ALG8 locus. |
Journal |
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Sequence |
|
Reference |
|
Authors |
Oriol R, Martinez-Duncker I, Chantret I, Mollicone R, Codogno P. |
Title |
Common origin and evolution of glycosyltransferases using Dol-P-monosaccharides as donor substrate. |
Journal |
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