KEGG   ORTHOLOGY: K03914Help
Entry
K03914                      KO                                     

Name
F2R, PAR1
Definition
coagulation factor II (thrombin) receptor
Pathway
ko04015  Rap1 signaling pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04610  Complement and coagulation cascades
ko04611  Platelet activation
ko04810  Regulation of actin cytoskeleton
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04020 Calcium signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04072 Phospholipase D signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04024 cAMP signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04151 PI3K-Akt signaling pathway
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
  Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 Organismal Systems
  Immune system
   04610 Complement and coagulation cascades
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
   04611 Platelet activation
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
G protein-coupled receptors [BR:ko04030]
 Class A. Rhodopsin family
  Complement peptide
   Thrombin
    K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
BRITE hierarchy
Other DBs
GO: 0015057
Genes
HSA: 2149(F2R)
PTR: 471510(F2R)
PPS: 100986369(F2R)
GGO: 101144448(F2R)
PON: 100447792(F2R)
NLE: 100607663(F2R)
MCC: 707370(F2R)
MCF: 102137130(F2R)
CSAB: 103223358(F2R)
RRO: 104653757(F2R)
RBB: 108513076(F2R)
CJC: 100400356(F2R)
SBQ: 101048036(F2R)
MMU: 14062(F2r)
RNO: 25439(F2r)
CGE: 100758351(F2r)
NGI: 103752270(F2r)
HGL: 101708544(F2r)
CCAN: 109701102(F2r)
OCU: 100351711(F2R)
TUP: 102485895(F2R)
CFA: 488942(F2R)
AML: 105240499(F2R)
UMR: 103663554(F2R)
ORO: 101364644(F2R)
FCA: 101100861(F2R)
PTG: 102964799(F2R)
AJU: 106974801(F2R)
BTA: 526585(F2R)
BOM: 102272347(F2R)
BIU: 109564649(F2R)
PHD: 102331468(F2R)
CHX: 102187491(F2R)
OAS: 101105757(F2R)
SSC: 100521609(F2R)
CFR: 102506154(F2R)
CDK: 105084810(F2R)
BACU: 103006270(F2R)
LVE: 103078013(F2R)
OOR: 101278325(F2R)
ECB: 100073278(F2R)
EPZ: 103540011(F2R)
EAI: 106824041(F2R)
MYB: 102249171(F2R)
MYD: 102770826(F2R)
HAI: 109381883(F2R)
RSS: 109445627(F2R)
PALE: 102886001(F2R)
LAV: 100668995(F2R)
TMU: 101358047
MDO: 100010071(F2R)
SHR: 100934757(F2R)
GGA: 427212(F2R)
MGP: 100543186(F2R)
CJO: 107306072(F2R)
APLA: 101804311(F2R)
ACYG: 106042104(F2R)
TGU: 100220661(F2R)
GFR: 102045591(F2R)
FAB: 101809495(F2R)
PHI: 102108910(F2R)
PMAJ: 107215843(F2R)
CCW: 104698561(F2R)
FPG: 101917626(F2R)
FCH: 102055206(F2R)
CLV: 102096136(F2R)
EGZ: 104124890(F2R)
AAM: 106489297(F2R) 106496616
ASN: 102371571(F2R)
AMJ: 102559171(F2R)
PSS: 102462418(F2R)
CMY: 102932450(F2R)
CPIC: 101935056(F2R)
ACS: 100566666(f2r) 107982334
PVT: 110084596 110084597(F2R)
PBI: 103063671(F2R) 103064541
XLA: 108707268(f2r.S) 378526(f2r.L)
XTR: 100493325(f2r)
DRE: 100149161 558477(f2r) 794215 794278(si:dkey-163m14.6) 794365(si:dkey-163m14.7) 799082(si:dkey-163m14.2) 799156 799227
IPU: 108255687(f2r)
TRU: 101072420(f2r) 101078307
LCO: 104926611(f2r) 104929263
NCC: 104954982(f2r)
PRET: 103470430(f2r) 103473499
NFU: 107374832 107393891(f2r)
CSEM: 103389897 103398127(f2r)
LCF: 108873765 108878175(f2r)
HCQ: 109514170(f2r) 109529262
BPEC: 110156751(f2r) 110157418
LCM: 102349897(F2R) 102362466
MYI: 110451394
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, Coughlin SR
  Title
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin.
  Journal
J Clin Invest 103:879-87 (1999)
DOI:10.1172/JCI6042
  Sequence
[hsa:2149]

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