KEGG   ORTHOLOGY: K03994
Entry
K03994                      KO                                     

Name
C5
Definition
complement component 5
Pathway
ko04080  Neuroactive ligand-receptor interaction
ko04610  Complement and coagulation cascades
ko04613  Neutrophil extracellular trap formation
ko05020  Prion disease
ko05133  Pertussis
ko05150  Staphylococcus aureus infection
ko05168  Herpes simplex virus 1 infection
ko05171  Coronavirus disease - COVID-19
ko05322  Systemic lupus erythematosus
Disease
H00103  Late complement pathway defects
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K03994  C5; complement component 5
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03994  C5; complement component 5
   04613 Neutrophil extracellular trap formation
    K03994  C5; complement component 5
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K03994  C5; complement component 5
   05168 Herpes simplex virus 1 infection
    K03994  C5; complement component 5
  09171 Infectious disease: bacterial
   05133 Pertussis
    K03994  C5; complement component 5
   05150 Staphylococcus aureus infection
    K03994  C5; complement component 5
  09163 Immune disease
   05322 Systemic lupus erythematosus
    K03994  C5; complement component 5
  09164 Neurodegenerative disease
   05020 Prion disease
    K03994  C5; complement component 5
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03994  C5; complement component 5
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   K03994  C5; complement component 5
Genes
HSA: 727(C5)
PTR: 464703(C5)
PPS: 100986224(C5)
GGO: 101138867(C5)
PON: 100461390(C5)
NLE: 100606437(C5)
MCC: 700467(C5)
MCF: 102125658(C5)
CSAB: 103218914(C5)
RRO: 104655862(C5)
RBB: 108537092(C5)
CJC: 100389486(C5)
SBQ: 101040214(C5)
MMU: 15139(Hc)
MCAL: 110285518(C5)
MPAH: 110317539(C5)
RNO: 362119(C5)
CGE: 100753880
NGI: 103734494
CCAN: 109702060(C5)
CFA: 474816(C5)
VVP: 112923109(C5)
AML: 100483168(C5)
UMR: 103670372(C5)
UAH: 113266354(C5)
ORO: 101364833(C5)
ELK: 111145939
FCA: 101090401(C5)
PTG: 102962969
AJU: 106986632(C5)
BTA: 512045(C5)
BOM: 102287871(C5)
BIU: 109563409(C5)
BBUB: 102400518(C5)
CHX: 102183419(C5)
OAS: 101121825
SSC: 414437(C5)
CDK: 105104667(C5)
BACU: 103010283(C5)
LVE: 103085597(C5)
OOR: 101279383(C5)
DLE: 111177265(C5)
PCAD: 102979563(C5)
ECB: 100067655(C5)
EPZ: 103550423(C5)
EAI: 106824223(C5)
MYB: 102238719(C5)
MYD: 102774153(C5)
MNA: 107537619(C5)
HAI: 109385735(C5)
DRO: 112306366(C5)
PALE: 102894162(C5)
RAY: 107516309(C5)
LAV: 100676780(C5)
TMU: 101350370
MDO: 100015572(C5)
SHR: 100928673(C5)
PCW: 110211344(C5)
OAA: 100681650(C5)
GGA: 417122(C5)
MGP: 100538532(C5)
CJO: 107321798(C5)
NMEL: 110406963(C5)
APLA: 101792161 101797076(C5)
ACYG: 106040728(C5)
TGU: 100227865(C5)
LSR: 110477651(C5)
SCAN: 103819113(C5)
GFR: 102039071(C5)
FAB: 101820036(C5)
PHI: 102107736(C5)
PMAJ: 107212134(C5)
CCAE: 111937084(C5)
CCW: 104688506(C5)
ETL: 114058497(C5)
FPG: 101921265(C5)
FCH: 102059706(C5)
CLV: 102086183(C5)
EGZ: 104135229(C5)
NNI: 104023309(C5)
ACUN: 113486471(C5)
PADL: 103915323(C5)
AAM: 106482012(C5)
ASN: 102378186(C5)
AMJ: 102559004(C5)
PSS: 102462992(C5)
CMY: 102929466(C5)
CPIC: 101946131(C5)
PVT: 110087438(C5)
PBI: 103062116(C5)
PMUR: 107298669(C5)
PMUA: 114589253(C5)
GJA: 107124805(C5)
XTR: 100485433(c5)
NPR: 108793646(C5)
DRE: 565774(c5)
SRX: 107731043(c5)
SANH: 107688630(c5)
SGH: 107587712(c5)
CCAR: 109082348
IPU: 108255659(c5)
PHYP: 113542523(c5)
AMEX: 103042674(c5)
EEE: 113573027(c5)
TRU: 101065841(c5)
MZE: 101468953(c5)
ONL: 100703748(c5)
OLA: 101172664(c5)
XMA: 102229911(c5)
XCO: 114144922(c5)
PRET: 103460569(c5)
CVG: 107097911(c5)
NFU: 107386161(c5)
KMR: 108241562(c5)
ALIM: 106527825(c5)
AOCE: 111566913(c5)
CSEM: 103397976
POV: 109645569
LCF: 108894954(c5)
SDU: 111238159(c5)
SLAL: 111668547(c5)
HCQ: 109525271(c5)
BPEC: 110159192
MALB: 109957435(c5)
SASA: 106587008(c5)
OTW: 112248904(c5)
SALP: 111974637(c5)
ELS: 105030204(c5)
PKI: 111842694(c5)
LCM: 102364499(C5)
CMK: 103184614(c5)
RTP: 109915369(c5)
 » show all
Reference
PMID:1984448
  Authors
Haviland DL, Haviland JC, Fleischer DT, Hunt A, Wetsel RA
  Title
Complete cDNA sequence of human complement pro-C5. Evidence of truncated transcripts derived from a single copy gene.
  Journal
J Immunol 146:362-8 (1991)
  Sequence
[hsa:727]
Reference
  Authors
Hawksworth OA, Coulthard LG, Taylor SM, Wolvetang EJ, Woodruff TM
  Title
Brief report: complement C5a promotes human embryonic stem cell pluripotency in the absence of FGF2.
  Journal
Stem Cells 32:3278-84 (2014)
DOI:10.1002/stem.1801
  Sequence
[hsa:727]

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