KEGG   ORTHOLOGY: K04438Help
Entry
K04438                      KO                                     

Name
CRK, CRKII
Definition
proto-oncogene C-crk
Pathway
ko04010  MAPK signaling pathway
ko04012  ErbB signaling pathway
ko04015  Rap1 signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04666  Fc gamma R-mediated phagocytosis
ko04722  Neurotrophin signaling pathway
ko04810  Regulation of actin cytoskeleton
ko04910  Insulin signaling pathway
ko05100  Bacterial invasion of epithelial cells
ko05131  Shigellosis
ko05163  Human cytomegalovirus infection
ko05200  Pathways in cancer
ko05206  MicroRNAs in cancer
ko05211  Renal cell carcinoma
ko05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K04438  CRK, CRKII; proto-oncogene C-crk
   04010 MAPK signaling pathway
    K04438  CRK, CRKII; proto-oncogene C-crk
   04012 ErbB signaling pathway
    K04438  CRK, CRKII; proto-oncogene C-crk
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K04438  CRK, CRKII; proto-oncogene C-crk
  Cell motility
   04810 Regulation of actin cytoskeleton
    K04438  CRK, CRKII; proto-oncogene C-crk
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    K04438  CRK, CRKII; proto-oncogene C-crk
   04062 Chemokine signaling pathway
    K04438  CRK, CRKII; proto-oncogene C-crk
  Endocrine system
   04910 Insulin signaling pathway
    K04438  CRK, CRKII; proto-oncogene C-crk
  Nervous system
   04722 Neurotrophin signaling pathway
    K04438  CRK, CRKII; proto-oncogene C-crk
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K04438  CRK, CRKII; proto-oncogene C-crk
   05206 MicroRNAs in cancer
    K04438  CRK, CRKII; proto-oncogene C-crk
   05220 Chronic myeloid leukemia
    K04438  CRK, CRKII; proto-oncogene C-crk
   05211 Renal cell carcinoma
    K04438  CRK, CRKII; proto-oncogene C-crk
  Infectious diseases
   05131 Shigellosis
    K04438  CRK, CRKII; proto-oncogene C-crk
   05100 Bacterial invasion of epithelial cells
    K04438  CRK, CRKII; proto-oncogene C-crk
   05163 Human cytomegalovirus infection
    K04438  CRK, CRKII; proto-oncogene C-crk
BRITE hierarchy
Genes
HSA: 1398(CRK) 1399(CRKL)
PTR: 107970369(CRKL) 747142(CRK)
PPS: 100973798(CRKL) 100976587(CRK)
GGO: 101127403(CRKL) 101154185(CRK) 109025578
PON: 100443298(CRKL) 100452410(CRK)
NLE: 100595820(CRKL) 100601245(CRK)
MCC: 696584(CRKL) 701185(CRK)
MCF: 101865065(CRK) 102122623(CRKL)
CSAB: 103222955(CRKL) 103242119(CRK)
RRO: 104666852(CRKL) 104670311(CRK)
RBB: 108524318(CRK) 108536084(CRKL)
CJC: 100390206(CRKL) 100399916(CRK)
SBQ: 101029260(CRK) 101051048(CRKL)
MMU: 12928(Crk) 12929(Crkl)
RNO: 100911248 287942(Crkl) 54245(Crk)
CGE: 100752014(Crkl) 100762827(Crk)
NGI: 103730505(Crk) 103741458(Crkl)
HGL: 101705695(Crkl) 101717585(Crk)
CCAN: 109682600(Crk) 109684371(Crkl)
OCU: 100342327(CRKL) 100358552(CRK)
TUP: 102482865(CRKL) 102486599(CRK)
CFA: 100684309(CRK) 608125(CRKL)
AML: 100466609(CRKL) 100467322(CRK)
UMR: 103667390(CRK) 103669230(CRKL)
ORO: 101369015(CRKL) 101384062(CRK)
FCA: 101084908(CRKL) 101086100(CRK)
PTG: 102956621(CRK) 102957241(CRKL)
AJU: 106983188(CRK) 106989988(CRKL)
BTA: 512841(CRK) 518180(CRKL)
BOM: 102277025(CRKL) 102278844(CRK)
BIU: 109570977(CRKL) 109573847(CRK)
PHD: 102318586(CRK) 102329125(CRKL)
CHX: 102174330(CRK) 102175206(CRKL)
OAS: 101115380(CRK) 101117537(CRKL)
SSC: 100192444(CRK) 100525363(CRKL)
CFR: 102511476(CRK) 102516584(CRKL)
CDK: 105088123(CRK) 105095221(CRKL)
BACU: 103001411(CRK) 103020871(CRKL)
LVE: 103087905(CRK) 103090463(CRKL)
OOR: 101270546(CRKL) 101284062(CRK)
ECB: 100050855(CRKL) 100072356(CRK)
EPZ: 103543614(CRKL) 103547531(CRK)
EAI: 106822010(CRK) 106848274(CRKL)
MYB: 102248665(CRKL) 102252934(CRK) 102253195
MYD: 102758195(CRK) 102761799(CRKL)
HAI: 109376239(CRKL) 109386906(CRK)
RSS: 109433705(CRKL) 109460262(CRK)
PALE: 102885553(CRK) 102898080(CRKL)
LAV: 100659273(CRK) 100662046(CRKL)
MDO: 100012317(CRK) 100015312(CRKL)
SHR: 100923581
OAA: 100076081(CRKL) 100092854(CRK)
GGA: 107054794(CRK) 416939(CRKL)
MGP: 100538907(CRKL) 100550512(CRK)
CJO: 107321452(CRKL) 107322427(CRK)
APLA: 101793961(CRK) 101804570(CRKL)
ACYG: 106031307(CRKL) 106041393(CRK)
TGU: 100217513(CRK) 100222846(CRKL) 100230536
GFR: 102039553(CRKL) 102040219(CRK)
FAB: 101807715(CRK) 101808629(CRKL)
PHI: 102102139(CRK) 102102631(CRKL)
PMAJ: 107211597(CRKL) 107212927(CRK)
CCW: 104688581(CRKL) 104691074(CRK)
FPG: 101911148(CRKL) 101920078(CRK)
FCH: 102048492(CRK) 102051164(CRKL)
CLV: 102091247(CRK) 102092831(CRKL)
EGZ: 104130098(CRKL) 104131823(CRK)
AAM: 106486247(CRKL) 106487715(CRK)
ASN: 102371723(CRKL) 102377791(CRK)
AMJ: 102557881(CRKL) 102559298(CRK)
CMY: 102942619 102944956(CRK)
CPIC: 101935800(CRK) 101936589(CRKL) 101939540
PVT: 110081775 110081994(CRKL) 110084280(CRK)
GJA: 107108519(CRKL) 107117460 107119408(CRK)
XLA: 108709342(crk.S) 398951(crk.L) 414569(crkl.S) 447419(crkl.L)
XTR: 394657(crkl) 448023(crk)
NPR: 108801710(CRK) 108802369(CRKL)
DRE: 445234(crk) 556443(crkl)
IPU: 108260055 108278187(crk) 108278795(crkl)
AMEX: 103035530(crk) 103038949 103044277(crkl)
TRU: 101065989 101078357(crkl) 101079298(crk)
LCO: 104919174 104920095(crkl) 104920874(crk)
NCC: 104945371(crkl) 104946431
OLA: 101157634(crk) 101164077(crkl) 110016423
XMA: 102218757 102219651(crkl) 102236416(crk)
PRET: 103473580(crkl) 103474879(crk) 103476349
LCF: 108879264(crkl) 108888177(crk) 108891917
BPEC: 110160359(crk) 110166352(crkl)
CMK: 103174463(crk) 103189634(crkl)
SPU: 577062
SKO: 102803663
DME: Dmel_CG1587(Crk)
DSI: Dsimw501_GD14194(Dsim_GD14194)
MDE: 101900499
AAG: 5568068
AME: 409578
BIM: 100744152
BTER: 100651298
SOC: 105201164
AEC: 105146358
ACEP: 105627820
PBAR: 105426254
HST: 105190213
CFO: 105252989
LHU: 105671279
PGC: 109855779
NVI: 100119269
TCA: 658768
DPA: 109532920
BMOR: 101745959
PMAC: 106711277
PRAP: 111001145
PXY: 105386226
API: 100164632
DNX: 107172591
ZNE: 110834965
TUT: 107360227
CEL: CELE_Y41D4B.13(ced-2)
CBR: CBG13568(Cbr-ced-2)
BMY: Bm1_39615
TSP: Tsp_06038
CRG: 105330355
MYI: 110450258
OBI: 106869162
LAK: 106154936
SHX: MS3_04393
ADF: 107340353
AQU: 100636612
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Feller SM
  Title
Crk family adaptors-signalling complex formation and biological roles.
  Journal
Oncogene 20:6348-71 (2001)
DOI:10.1038/sj.onc.1204779
Reference
PMID:1630456
  Authors
Matsuda M, Tanaka S, Nagata S, Kojima A, Kurata T, Shibuya M
  Title
Two species of human CRK cDNA encode proteins with distinct biological activities.
  Journal
Mol Cell Biol 12:3482-9 (1992)
  Sequence
[hsa:1398]

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