KEGG ORTHOLOGY: K04465

ORTHOLOGY: K04465

Entry

K04465                      KO

Symbol

NR4A1, HMR

Name

nuclear receptor subfamily 4 group A member 1

Pathway

map04010

MAPK signaling pathway

map04151

PI3K-Akt signaling pathway

map04925

Aldosterone synthesis and secretion

map04927

Cortisol synthesis and secretion

map04934

Cushing syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
   04151 PI3K-Akt signaling pathway
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
   04927 Cortisol synthesis and secretion
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys4 nerve growth factor IB-like
    K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
Nuclear receptors [BR:ko03310]
4. Nerve growth factor IB like
  4A. Nerve growth factor IB like receptor
   K04465  NR4A1, HMR; nuclear receptor subfamily 4 group A member 1

Genes

HSA:	3164(NR4A1)

PTR:	451913(NR4A1)

PPS:	100976569(NR4A1)

GGO:	101148131(NR4A1)

PON:	100172457(NR4A1)

NLE:	100606340(NR4A1)

HMH:	116461658(NR4A1)

MCC:	696797(NR4A1)

MCF:	102146285(NR4A1)

MTHB:

126931034

MNI:	105474331(NR4A1)

CSAB:

103238335(NR4A1)

CATY:

105580323(NR4A1)

PANU:

101021171(NR4A1)

TGE:	112634399(NR4A1)

MLEU:

105555401(NR4A1)

RRO:	104670651(NR4A1)

RBB:	108521591(NR4A1)

TFN:	117090100(NR4A1)

PTEH:

111541979(NR4A1)

CANG:

105503620(NR4A1)

CJC:	100392818(NR4A1)

SBQ:	101039973(NR4A1)

CIMI:

108316108(NR4A1)

CSYR:

103268421(NR4A1)

MMUR:

105870310(NR4A1)

LCAT:

123639819(NR4A1)

PCOQ:

105817898(NR4A1)

OGA:	100956281(NR4A1)

MMU:	15370(Nr4a1)

MCAL:

110310281(Nr4a1)

MPAH:

110334786(Nr4a1)

RNO:	79240(Nr4a1)

MCOC:

116080043(Nr4a1)

ANU:	117718915(Nr4a1)

MUN:	110559141(Nr4a1)

CGE:	100764218(Nr4a1)

MAUA:

101832083(Nr4a1)

PROB:

127226095(Nr4a1)

PLEU:

114696655(Nr4a1)

MORG:

121444253(Nr4a1)

MFOT:

126488791

AAMP:

119823130(Nr4a1)

NGI:	103739583(Nr4a1)

HGL:	101707788(Nr4a1)

CPOC:

100732875(Nr4a1)

CCAN:

109685524 109685527(Nr4a1)

DORD:

105987566(Nr4a1)

DSP:	122098417(Nr4a1) 122102946 122107928 122107929 122108067 122108068 122108069 122108071 122108072

PLOP:

125364508(Nr4a1)

NCAR:

124982326

MMMA:

107148647(Nr4a1)

OCU:

100349994

OPI:	101518457(NR4A1)

TUP:	102490723(NR4A1)

GVR:	103585224(NR4A1)

CFA:	403897(NR4A1)

CLUD:

112667240(NR4A1)

VVP:	112921157(NR4A1)

VLG:	121480247(NR4A1)

NPO:	129517389(NR4A1)

AML:	100481851(NR4A1)

UMR:	103675500(NR4A1)

UAH:	113257593(NR4A1)

UAR:	123794728(NR4A1)

ELK:

111157882

LLV:

125107277

MPUF:

101676286(NR4A1)

MNP:	132019697(NR4A1)

MLK:	131838743(NR4A1)

NVS:	122891486(NR4A1)

ORO:	101375462(NR4A1)

EJU:

114225887

ZCA:	113922988(NR4A1)

MLX:	118008825(NR4A1)

NSU:	110593540(NR4A1)

LWW:	102728961(NR4A1) 102732653

FCA:	101097902(NR4A1)

PYU:	121038550(NR4A1)

PCOO:

112867470(NR4A1)

PBG:	122473418(NR4A1)

PVIV:

125170795(NR4A1)

LRUF:

124502336

PTG:	102972691(NR4A1)

PPAD:

109249134(NR4A1)

PUC:

125919068

AJU:

106986411

HHV:	120237917(NR4A1)

BTA:	528390(NR4A1)

BOM:	102288141(NR4A1)

BIU:	109559075(NR4A1)

BBUB:

102393496(NR4A1)

BBIS:

105001536(NR4A1)

CHX:	102185438(NR4A1)

OAS:	101113222(NR4A1)

BTAX:

128047279(NR4A1)

ODA:	120858245(NR4A1)

CCAD:

122427135(NR4A1)

MBEZ:

129535747(NR4A1)

CFR:	102509959(NR4A1)

CBAI:

105076251(NR4A1)

CDK:	105100389(NR4A1)

VPC:	102529736(NR4A1)

BACU:

103020888(NR4A1)

BMUS:

118901728(NR4A1)

LVE:	103077071(NR4A1)

OOR:	101273386(NR4A1)

DLE:	111173979(NR4A1)

PCAD:

102993259(NR4A1)

PSIU:

116760487(NR4A1)

NASI:

112394274(NR4A1)

ECB:	100061353(NR4A1)

EPZ:	103561297(NR4A1)

EAI:	106835239(NR4A1)

MYB:	102245718(NR4A1)

MYD:	102764884(NR4A1)

MMYO:

118650824(NR4A1)

MLF:	102428614(NR4A1)

PKL:	118729448(NR4A1)

EFUS:

103285309(NR4A1)

MNA:	107528285(NR4A1)

DRO:	112318469(NR4A1)

SHON:

118976446(NR4A1)

AJM:	119043398(NR4A1)

PDIC:

114513257(NR4A1)

PHAS:

123812630(NR4A1)

MMF:	118623887(NR4A1)

PPAM:

129084834(NR4A1)

HAI:	109371418(NR4A1)

RFQ:	117029230(NR4A1)

PALE:

102884629(NR4A1)

PGIG:

120602137(NR4A1)

PVP:	105307011(NR4A1)

RAY:	107509823(NR4A1)

MJV:	108398275(NR4A1)

TOD:	119247943(NR4A1)

SARA:

101541836(NR4A1)

SETR:

126022480(NR4A1)

LAV:	100654848(NR4A1)

TMU:

101346441

ETF:	101659859(NR4A1)

DNM:	101412781(NR4A1)

GAS:	123250666(NR4A1)

SHR:	100931514(NR4A1)

AFZ:

127539484

PCW:	110194004(NR4A1)

OAA:	100080213(NR4A1)

GGA:	100857380(NR4A1)

PCOC:

116236090(NR4A1)

MGP:

104916194

CJO:	107325726(NR4A1)

NMEL:

110391829

APLA:

101800531(NR4A1)

ACYG:

106047711(NR4A1)

CATA:

118260224(NR4A1)

AFUL:

116499970(NR4A1)

TGU:	100231563(NR4A1)

LSR:	110480386(NR4A1)

SCAN:

103824614(NR4A1)

PMOA:

120499480(NR4A1)

OTC:	121334298(NR4A1)

PRUF:

121356346(NR4A1)

GFR:	102032525(NR4A1)

FAB:	101809771(NR4A1)

OMA:	130265768(NR4A1)

PHI:	102105460(NR4A1)

PMAJ:

107198608(NR4A1)

CCAE:

111940500(NR4A1)

CBRC:

103611923(NR4A1)

ETL:	114070446(NR4A1)

ZAB:

102065140

ACHL:

103811152

SVG:	106862691(NR4A1)

MMEA:

130586317(NR4A1)

HRT:	120764518(NR4A1)

FCH:

102051357

CLV:	102093626(NR4A1)

EGZ:

104122503

NNI:	104011991(NR4A1)

TALA:

116962491(NR4A1)

AFOR:

103894929(NR4A1)

ACHC:

115350990(NR4A1)

HLE:	104831147(NR4A1)

AGEN:

126046555

SHAB:

115618671(NR4A1)

ACAR:

104529362

CVF:	104284827(NR4A1)

RTD:	128901235(NR4A1)

CUCA:

104057951(NR4A1)

AROW:

112975224(NR4A1)

NPD:	112950309(NR4A1)

ASN:	102386947(NR4A1)

AMJ:	102572473(NR4A1)

CPOO:

109324482(NR4A1)

PSS:	102454484(NR4A1)

CMY:	102941279(NR4A1)

CCAY:

125627443(NR4A1)

DCC:	119846065(NR4A1)

CPIC:

101945782(NR4A1)

TST:	117888763(NR4A1)

CABI:

116827803(NR4A1)

MRV:	120391182(NR4A1)

ACS:	100559576(nr4a1)

ASAO:

132768305(NR4A1)

PVT:	110074442(NR4A1)

SUND:

121920637(NR4A1)

PBI:	103050500(NR4A1)

PMUR:

107290999(NR4A1)

CTIG:

120305452(NR4A1)

TSR:	106556937(NR4A1)

PGUT:

117662781(NR4A1)

APRI:

131191062(NR4A1)

PTEX:

113447350(NR4A1)

NSS:	113420181(NR4A1)

VKO:	123019242(NR4A1)

PMUA:

114586719(NR4A1)

PRAF:

128407091(NR4A1)

ZVI:	118079324(NR4A1)

HCG:	128345219(NR4A1)

GJA:	107126140(NR4A1)

STOW:

125429017(NR4A1)

EMC:	129328620(NR4A1)

XLA:	373674(nr4a1.L) 379851(nr4a1.S)

XTR:	779756(nr4a1)

NPR:	108798619(NR4A1)

RTEM:

120929600(NR4A1)

BBUF:

120995941(NR4A1)

BGAR:

122932095(NR4A1)

MUO:	115465954(NR4A1)

GSH:	117356663(NR4A1)

DRE:	431720(nr4a1)

SRX:	107723761 107756405

SANH:

107671891 107701750

SGH:	107549046 107572787

CCAR:

109063360 109068875

CAUA:

113041417 113065615

CGIB:

127945131 128011846

PTET:

122328669(nr4a1)

LROH:

127154818(nr4a1)

OMC:	131532651(nr4a1)

PPRM:

120463248(nr4a1)

RKG:	130075534(nr4a1)

MAMB:

125260026(nr4a1)

CIDE:

127505057

MASI:

127418673 127420449

TROS:

130572053(nr4a1)

TDW:	130409043(nr4a1)

MANU:

129430338(nr4a1)

IPU:	108255274 108276383(nr4a1)

IFU:	128619659(nr4a1) 128625184

PHYP:

113538122 113545673

SMEO:

124399246(nr4a1) 124402483

TFD:	113635269(nr4a1) 113661979

TVC:	132838246 132862457(nr4a1)

AMEX:

103033875 103040841

CMAO:

118799563 118822639(nr4a1)

EEE:	113587260 113588695

CHAR:

105897944(nr4a1)

TRU:	101076406 101077057

TFS:	130524896 130529923(nr4a1)

TNG:	GSTEN00013617G001 GSTEN00023538G001

LCO:	104931814 109141859

NCC:	104954755(nr4a1)

TBEN:

117487521(nr4a1) 117489883

CGOB:

115008150

PGEO:

117446099 117448849(nr4a1)

GACU:

117534254

EMAC:

134871025(nr4a1) 134882498

ELY:	117257477 117257686(nr4a1)

EFO:	125891793 125891941(nr4a1)

PLEP:

121947123(nr4a1) 121953457

SLUC:

116043541(nr4a1) 116066582

ECRA:

117943407 117947683(nr4a1)

ESP:	116679810 116688504 116692062

PFLV:

114553786 114559239

GAT:	120829068(nr4a1) 120835612

PPUG:

119193942 119223793(nr4a1)

AFB:	129099948(nr4a1) 129105970

CLUM:

117730957 117733658(nr4a1)

PSWI:

130199602(nr4a1) 130209013

MSAM:

119886035 119906135(nr4a1)

SCHU:

122867472 122883655(nr4a1)

CUD:	121518223(nr4a1) 121528706

ALAT:

119021222 119022338(nr4a1)

MZE:	101463795 101487394

ONL:	100709859 100709939

OAU:	116322044(nr4a1) 116329890

OLA:	101165550 101175402(nr4a1)

OML:	112145583 112159811(nr4a1)

CSAI:

133448687 133456753(nr4a1)

XMA:	102220936 102238311

XCO:	114136284 114140408

XHE:	116710208 116714851

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122832164(nr4a1) 122834651

PPRL:

129358357 129370428(nr4a1)

CVG:	107088730 107099669

CTUL:

119791805 119799323(nr4a1)

GMU:	124856205 124871988(nr4a1)

NFU:	107385615 107390383

KMR:	108235662 108237592(nr4a1)

ALIM:

106513281 106522968

NWH:	119411950 119417467(nr4a1)

AOCE:

111579757 111583387

MCEP:

125006514 125021683(nr4a1)

CSEM:

103385572 103386020

POV:	109628858 109640607

SSEN:

122767578 122777050(nr4a1)

HHIP:

117761201 117764861(nr4a1)

HSP:	118104857 118110808(nr4a1)

SMAU:

118309807 118317503(nr4a1)

LCF:	108884173(nr4a1) 108898936

SDU:	111221484 111234938

SLAL:

111661944 111667775

XGL:	120803926(nr4a1) 120807190

HCQ:	109513030 109522594

SSCV:

125977070 125988494

SBIA:

133508009(nr4a1)

PEE:	133399799 133409188

PTAO:

133476933 133483980

BPEC:

110164632 110171290

MALB:

109956206 109970280

BSPL:

114856029 114859076(nr4a1)

SJO:	128355528 128357035(nr4a1)

SASA:

106565406 106567334 106572532 106583344

STRU:

115150425 115165668 115168011 115208000

OTW:	112215925 112216241 112221413 112254749

OMY:	110492115 110494169 110528258 110532548

OGO:	124003531 124022832 124030908 124045131

ONE:	115102420 115132390 115141415 115143039

OKI:	109869612 109891224 109894265 109908202

OKE:	118359477 118360783 118388715 118400421

SALP:

111965121 111977129

SNH:	120061245 120062345 120065235

CCLU:

121537425 121545716 121575123 121577800

ELS:	105017087 105022309

SFM:	108918437 108939385

PKI:	111840385(nr4a1) 111854743

AANG:

118208521(nr4a1) 118211770

LOC:	102691792(nr4a1)

PSPA:

121308815(nr4a1)

ARUT:

117401111 117967103

PSEX:

120524837(nr4a1)

LCM:	102364494(NR4A1)

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133339997 133344752 133349853

RZE:

CCIN:

TSP:

MCAF:

SPIS:

DGT:

XEN:

Reference

PMID:25089663

Authors

Ranhotra HS

Title

The NR4A orphan nuclear receptors: mediators in metabolism and diseases.

Journal

J Recept Signal Transduct Res 35:184-8 (2015)
DOI:10.3109/10799893.2014.948555

Reference

PMID:2283997

Authors

Nakai A, Kartha S, Sakurai A, Toback FG, DeGroot LJ

Title

A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily.

Journal

Mol Endocrinol 4:1438-43 (1990)
DOI:10.1210/mend-4-10-1438

Sequence

[hsa:3164]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Gene (725)   
   KEGG GENES (490)   
   KEGG MGENES (78)   
   RefGene (154)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (740)   

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