KEGG ORTHOLOGY: K04529

ORTHOLOGY: K04529

Entry

K04529                      KO

Symbol

APBB1, FE65

Name

amyloid beta A4 precursor protein-binding family B member 1

Pathway

map05010

Alzheimer disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04529  APBB1, FE65; amyloid beta A4 precursor protein-binding family B member 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K04529  APBB1, FE65; amyloid beta A4 precursor protein-binding family B member 1
Membrane trafficking [BR:ko04131]
Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    K04529  APBB1, FE65; amyloid beta A4 precursor protein-binding family B member 1

Other DBs

GO:

0001540

Genes

HSA:	322(APBB1)

PTR:	466415(APBB1)

PPS:	100993946(APBB1)

GGO:	101145867(APBB1)

PON:	100444276(APBB1)

PPYG:

129007872(APBB1)

NLE:	100584307(APBB1)

HMH:	116476587(APBB1)

SSYN:

129484474(APBB1)

MCC:	712585(APBB1)

MCF:	102134079(APBB1)

MTHB:

126935040

MNI:	105488685(APBB1)

CSAB:

103241488(APBB1)

CATY:

105575052(APBB1)

PANU:

101011492(APBB1)

TGE:	112605705(APBB1)

MLEU:

105533911(APBB1)

RRO:	104678294(APBB1)

RBB:	108543245(APBB1)

TFN:	117081497(APBB1)

PTEH:

111524616(APBB1)

CANG:

105520535(APBB1)

CJC:	100401543(APBB1)

SBQ:	101054303(APBB1)

CIMI:

108288334(APBB1)

ANAN:

105720324(APBB1)

CSYR:

103267029(APBB1)

MMUR:

105883453(APBB1)

LCAT:

123642354(APBB1)

PCOQ:

105818402(APBB1)

OGA:	100955791(APBB1)

MMU:	11785(Apbb1)

MCAL:

110299267(Apbb1)

MPAH:

110322725(Apbb1)

RNO:	29722(Apbb1)

MCOC:

116102727(Apbb1)

ANU:	117705534(Apbb1)

ASYL:

127663798(Apbb1)

MUN:	110559575(Apbb1)

CGE:	100760848(Apbb1)

MAUA:

101825033(Apbb1)

PROB:

127228096(Apbb1)

PLEU:

114683812(Apbb1)

MORG:

121457669(Apbb1)

MFOT:

126494098

AAMP:

119815122(Apbb1)

NGI:	103737561(Apbb1)

HGL:	101699658(Apbb1)

CPOC:

100735070(Apbb1)

CCAN:

109695571

DORD:

106000380(Apbb1)

DSP:	122117629(Apbb1)

DMER:

138836474(Apbb1)

PLOP:

125361384(Apbb1)

NCAR:

124959766

MMMA:

107135597(Apbb1)

ITI:	101960748(Apbb1)

OCU:

100354159

OPI:	101534321(APBB1)

TUP:	102470251(APBB1)

GVR:	103591273(APBB1)

CFA:	476833(APBB1)

CLUD:

112667548(APBB1)

VVP:	112910856(APBB1)

VLG:	121475949(APBB1)

NPO:	129505115(APBB1)

AML:	100475168(APBB1)

UMR:	103681412(APBB1)

UAH:	113245850(APBB1)

UAR:	123782743(APBB1)

ELK:

111159408

LLV:

125079363

MPUF:

101679977(APBB1)

MNP:	132023511(APBB1)

MLK:	131808559(APBB1)

NVS:	122912673(APBB1)

ORO:	101383633(APBB1)

EJU:	114219367(APBB1)

ZCA:	113915039(APBB1)

MLX:	118004250(APBB1)

NSU:	110576519(APBB1)

LWW:	102739789(APBB1)

FCA:	101090045(APBB1)

PYU:	121021203(APBB1)

PCOO:

112865003(APBB1)

PBG:	122483492(APBB1)

PVIV:

125176866(APBB1)

LRUF:

124506370

LGF:	123601285(APBB1)

AJU:

106981171

PTG:	102964621(APBB1)

PPAD:

109271060(APBB1)

PUC:

125936802

PLEZ:

122199860(APBB1)

HHV:	120221439(APBB1)

BTA:	505096(APBB1)

BOM:	102282509(APBB1)

BIU:	109569728(APBB1)

BBUB:

102399367(APBB1)

BBIS:

104988010(APBB1)

CHX:	102179305(APBB1)

OAS:	101118129(APBB1)

BTAX:

128060069(APBB1)

CSUM:

138092409(APBB1)

ODA:	120876550(APBB1)

CCAD:

122449599(APBB1)

MREE:

136174423(APBB1)

OVR:	110138850(APBB1)

MBEZ:

129554589(APBB1)

SSC:	100519163(APBB1)

CFR:	102509996(APBB1)

CBAI:

105076697(APBB1)

CDK:	105097915(APBB1)

VPC:	102534654(APBB1)

BACU:

103020661(APBB1)

BMUS:

118899694(APBB1)

LVE:	103079605(APBB1)

OOR:	101269988(APBB1)

LALB:

132526062(APBB1)

GMF:	115839508(APBB1)

DDP:	132429733(APBB1)

DLE:	111169134(APBB1)

PCAD:

102973595(APBB1)

PSIU:

116758504(APBB1)

PPHC:

136127377(APBB1)

NASI:

112407702(APBB1)

ECB:	100069964(APBB1)

EPZ:	103553526(APBB1)

EAI:	106838186(APBB1)

MYB:	102245013(APBB1)

MYD:	102766669(APBB1)

MMYO:

118664755(APBB1)

MLF:	102421336(APBB1)

MDT:	132240905(APBB1)

MYUM:

139017261(APBB1)

PKL:	118713586(APBB1)

EFUS:

103302795(APBB1)

MNA:	107540502(APBB1)

DRO:	112312786(APBB1)

SHON:

118990804(APBB1)

AJM:	119041318(APBB1)

PDIC:

114500404(APBB1)

PHAS:

123819306(APBB1)

MMF:	118616772(APBB1)

PPAM:

129076401(APBB1)

HAI:	109376524(APBB1)

RFQ:	117030270(APBB1)

PALE:

102889333(APBB1)

PGIG:

120590240(APBB1)

PVP:	105309093(APBB1)

RAY:	107504368(APBB1)

MJV:	108408096(APBB1)

TOD:	119255535(APBB1)

SARA:

101545015(APBB1)

SFUM:

130025113(APBB1)

SETR:

126018140(APBB1)

LAV:	100668175(APBB1)

TMU:

101349337

ETF:	101648132(APBB1)

DNM:	101424680(APBB1)

MDO:	100030868(APBB1)

GAS:	123238633(APBB1)

SHR:	100914555(APBB1)

AFZ:

127555368

PCW:	110200479(APBB1)

TVP:	118839648(APBB1)

PBRV:

138176937(APBB1)

MLAO:

141508646(APBB1)

OAA:	100091194(APBB1)

TACU:

119947296(APBB1)

GGA:	100859045(APBB1)

PCOC:

116239498(APBB1)

CJO:	107308581(APBB1)

TPAI:

128088593(APBB1)

LMUT:

125695657(APBB1)

NMEL:

110391910(APBB1)

APLA:

113844595(APBB1)

ACYG:

106029364(APBB1)

CATA:

118259766(APBB1)

AFUL:

116502162(APBB1)

TGU:	105758628(APBB1)

LSR:	110474955(APBB1)

SCAN:

103824417(APBB1)

PMOA:

120499976(APBB1)

OTC:	121334222(APBB1)

PRUF:

121355113(APBB1)

ATRC:

139591441(APBB1)

FAB:	101809568(APBB1)

OMA:	130255045(APBB1)

PHI:	102113506(APBB1)

PMAJ:

107198240(APBB1)

CCW:	120410226(APBB1)

ACOE:

138114709(APBB1)

ETL:	114073160(APBB1)

ZLE:	135443968(APBB1)

SVG:	106861732(APBB1)

MMEA:

130582717(APBB1)

HRT:	120749570(APBB1)

SATI:

136358244(APBB1)

CCIC:

134058161(APBB1)

FPG:	101921489(APBB1)

FCH:	102052006(APBB1)

ACHC:

115353385(APBB1)

HLE:	104837585(APBB1)

AGEN:

126048355

HHAR:

128153442(APBB1)

CBOY:

140646712(APBB1)

CNIC:

135984571(APBB1)

RTD:	128915609(APBB1)

CRID:

134512922(APBB1)

AAM:	106488046(APBB1)

AROW:

112962029 112962031(APBB1)

DNE:	112993199(APBB1)

ASN:	102379643(APBB1)

AMJ:	102575958(APBB1)

CPOO:

109305569(APBB1)

GGN:	109302996(APBB1)

CMY:	114020870(APBB1)

CCAY:

125638135(APBB1)

DCC:	119842387(APBB1)

CPIC:

101950862(APBB1)

MRV:	120395559(APBB1)

ACS:	100560495(apbb1)

ASAO:

132772345(APBB1)

PVT:	110078162(APBB1)

SUND:

121926894(APBB1)

PBI:	103052263(APBB1) 103066899

PMUR:

107288665(APBB1)

CTIG:

120310122(APBB1)

PGUT:

117670864(APBB1)

PCAE:

139316390(APBB1)

NSS:	113426073(APBB1)

VKO:	123017337(APBB1)

PMUA:

114595148(APBB1)

PRAF:

128412047(APBB1)

ZVI:	118085046(APBB1)

HCG:	128350184(APBB1)

GJA:	107121987(APBB1)

STOW:

125430923(APBB1)

EMC:	129325621(APBB1)

XLA:	446838(apbb1.L)

XTR:	116408631(apbb1)

NPR:

108800934

RTEM:

120928849(APBB1)

ACAT:

141126745(APBB1)

BBUF:

120996636(APBB1)

BGAR:

122931049(APBB1)

DTC:

141076481

PWL:	138249689(APBB1)

MUO:	115459136 115468244(APBB1)

GSH:	117362073(APBB1)

DRE:	565164(apbb1)

SRX:	107705847 107750985

SANH:

107657440(apbb1) 107673752

SGH:	107565841 107573909

CCAR:

109097318(apbb1) 109097399

CAUA:

113053952(apbb1) 113109507

CGIB:

127966179 128021560

PTET:

122352763(apbb1)

LROH:

127162560(apbb1)

GRF:	141299690(apbb1)

OMC:	131548224(apbb1)

PPRM:

120479286 120486879

RKG:	130099806(apbb1)

MAMB:

125251329(apbb1)

CIDE:

127520566

CERY:

137028976(apbb1)

MASI:

127432447

TROS:

130545761(apbb1)

TDW:	130411474(apbb1)

MANU:

129446089(apbb1)

PDAB:

135745326(apbb1)

IPU:

108277238

IFU:	128620554(apbb1)

PHYP:

113543611(apbb1)

SMEO:

124393683(apbb1)

TFD:	113639327(apbb1)

TVC:	132863084(apbb1)

CGAR:

128505435(apbb1)

NGRA:

132873853(apbb1)

TRN:	134332212(apbb1)

AMEX:

103037961(apbb1)

CMAO:

118824539(apbb1)

EEE:	113567776(apbb1)

CHAR:

105901039(apbb1) 105901423

SPIL:

134080441(apbb1) 134100001

TRU:	101065587(apbb1)

TFS:	130534517(apbb1)

TNG:	GSTEN00038176G001

LCO:

104919839

NCC:	104947435(apbb1)

TBEN:

117468800(apbb1)

CGOB:

115017587(apbb1)

PGEO:

117457188(apbb1)

GACU:

117540483(apbb1)

EMAC:

134880141(apbb1)

ELY:	117259810(apbb1)

EFO:	125888372(apbb1)

PLEP:

121943014(apbb1)

SLUC:

116048456(apbb1)

ECRA:

117941900(apbb1)

ESP:	116671343(apbb1)

PFLV:

114552698(apbb1)

GAT:	120829472(apbb1)

PPUG:

119211651(apbb1)

AFB:	129092466(apbb1)

CLUM:

117741317(apbb1)

PSWI:

130210970(apbb1)

CANA:

137790497(apbb1)

CVE:	137875741(apbb1)

MSAM:

119882749(apbb1)

SCHU:

122879050(apbb1)

CUD:	121519493(apbb1)

SPUL:

138596959(apbb1)

LMIX:

132980674(apbb1)

ALAT:

119007187(apbb1)

ASTR:

137596677(apbb1)

MZE:	101485078(apbb1)

ONL:	100711146(apbb1)

OAU:	116335660(apbb1)

OLA:	101159765(apbb1)

OML:	112149445(apbb1)

CSAI:

133441906(apbb1)

XMA:

102226021

XCO:

114133687

XHE:	116707861(apbb1)

PRET:

103474124(apbb1)

PFOR:

103148509(apbb1)

PLAI:

106960550(apbb1)

PMEI:

106905081(apbb1)

GAF:	122832363(apbb1)

PPRL:

129369712(apbb1)

CVG:	107099541(apbb1)

CTUL:

119795419(apbb1)

GMU:	124884014(apbb1)

NFU:	107380009(apbb1)

KMR:	108236022(apbb1)

ALIM:

106529736(apbb1)

NWH:	119410708(apbb1)

AOCE:

111567869(apbb1)

EJA:	138205343(apbb1)

BFRE:

138628937(apbb1)

MCEP:

125013189(apbb1)

CSEM:

103378044(apbb1)

POV:	109630275(apbb1)

SSEN:

122773407(apbb1)

SSOE:

131462354(apbb1)

HHIP:

117772808(apbb1)

HSP:	118106100(apbb1)

PPLT:

128439949(apbb1)

SMAU:

118299324(apbb1)

LCF:

108876088

SDU:	111232288(apbb1)

SLAL:

111653642(apbb1)

XGL:	120791966(apbb1)

HCQ:	109527218(apbb1)

SSCV:

125972464(apbb1)

SBIA:

133504918(apbb1)

PEE:	133405104(apbb1)

PTAO:

133482316(apbb1)

BPEC:

110172715(apbb1)

ENY:	140373718(apbb1)

MALB:

109969743(apbb1)

BSPL:

114867712(apbb1)

SJO:	128360683(apbb1)

SSCO:

133980285(apbb1)

GMH:	115528975(apbb1)

SASA:

100380744(apbb1) 106568092 106603266 106613141

STRU:

115149135 115154588 115163686 115206566

OTW:	112250290 112257615 112266195 112267458

OMY:	110503161 110507999 110533887 110537232

OGO:	123992564 123999896 124005781 124008340

ONE:	115105784 115135706 115136591 115141984

OKI:	109873170 109876056 109892555 109905882

OKE:	118390298 118390751 118391367 118397570

OMM:	135546628 135548372 135550476 135553131

OCLA:

139382531 139385917 139418467 139422918

SALP:

111981927 111982852 112068901

SNH:	120018093 120028823 120045063 120057207

CCLU:

121566956 121567785 121573768 121579896

ELS:	105010782 105023566

OEP:	134028850 134039395

SFM:	108921287(apbb1)

PKI:	111837933 111852171

AANG:

118208832 118236127

AROT:

135236405(apbb1) 135264132

CCOG:

133108254 133132749

LOC:	102687478(apbb1)

PSPA:

121320435(apbb1)

ARUT:

117405715(apbb1)

LCM:	102359451(APBB1)

RTP:	109920985(apbb1)

CPLA:

122550991(apbb1)

HOC:	132816595(apbb1)

LERI:

HAKA:

VDE:

VJA:

DFR:

ATEN:

DGT:

XEN:

Reference

PMID:8894693

Authors

Bressler SL, Gray MD, Sopher BL, Hu Q, Hearn MG, Pham DG, Dinulos MB, Fukuchi K, Sisodia SS, Miller MA, Disteche CM, Martin GM

Title

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein.

Journal

Hum Mol Genet 5:1589-98 (1996)
DOI:10.1093/hmg/5.10.1589

Sequence

[hsa:322]

All links

Ontology (1)   
   GO (1)   
Gene (543)   
   MGENES (196)   
   RefGene (344)   
   OC (3)   
All databases (544)   

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