KEGG   ORTHOLOGY: K04603
Entry
K04603                      KO                                     

Name
GRM1
Definition
metabotropic glutamate receptor 1
Pathway
ko04020  Calcium signaling pathway
ko04068  FoxO signaling pathway
ko04072  Phospholipase D signaling pathway
ko04080  Neuroactive ligand-receptor interaction
ko04540  Gap junction
ko04720  Long-term potentiation
ko04723  Retrograde endocannabinoid signaling
ko04724  Glutamatergic synapse
ko04730  Long-term depression
ko04742  Taste transduction
ko04915  Estrogen signaling pathway
ko05017  Spinocerebellar ataxia
ko05022  Pathways of neurodegeneration - multiple diseases
Disease
H00063  Spinocerebellar ataxia (SCA)
H01891  Autosomal recessive spinocerebellar ataxias
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
   04020 Calcium signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
   04072 Phospholipase D signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04603  GRM1; metabotropic glutamate receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04603  GRM1; metabotropic glutamate receptor 1
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    K04603  GRM1; metabotropic glutamate receptor 1
  09156 Nervous system
   04724 Glutamatergic synapse
    K04603  GRM1; metabotropic glutamate receptor 1
   04720 Long-term potentiation
    K04603  GRM1; metabotropic glutamate receptor 1
   04730 Long-term depression
    K04603  GRM1; metabotropic glutamate receptor 1
   04723 Retrograde endocannabinoid signaling
    K04603  GRM1; metabotropic glutamate receptor 1
  09157 Sensory system
   04742 Taste transduction
    K04603  GRM1; metabotropic glutamate receptor 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K04603  GRM1; metabotropic glutamate receptor 1
   05022 Pathways of neurodegeneration - multiple diseases
    K04603  GRM1; metabotropic glutamate receptor 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04603  GRM1; metabotropic glutamate receptor 1
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04603  GRM1; metabotropic glutamate receptor 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04603  GRM1; metabotropic glutamate receptor 1
G protein-coupled receptors [BR:ko04030]
 Metabotropic glutamate receptor family
  Glutamate (metabotropic)
   K04603  GRM1; metabotropic glutamate receptor 1
Other DBs
GO: 0001639
TC: 9.A.14.7.1
Genes
HSA: 2911(GRM1)
PTR: 463049(GRM1)
PPS: 100968079(GRM1)
GGO: 101150458(GRM1)
PON: 100451342(GRM1)
NLE: 100592587(GRM1)
MCC: 698736(GRM1)
MCF: 102145647(GRM1)
CSAB: 103240205(GRM1)
CJC: 100410312(GRM1)
SBQ: 101036619(GRM1)
MMU: 14816(Grm1)
MCAL: 110303088(Grm1)
MPAH: 110338039(Grm1)
RNO: 24414(Grm1)
CGE: 100751598(Grm1)
NGI: 103737030(Grm1)
HGL: 101712477(Grm1)
OCU: 100356201(GRM1)
TUP: 102479064(GRM1)
CFA: 484024(GRM1)
VVP: 112919501(GRM1)
AML: 100479929(GRM1)
UAH: 113259527(GRM1)
ELK: 111147676
FCA: 101094104(GRM1)
PTG: 102961964(GRM1)
PPAD: 109252510(GRM1)
AJU: 106965803(GRM1)
BTA: 540485(GRM1)
BOM: 102280395(GRM1)
BIU: 109563668(GRM1)
BBUB: 102414394(GRM1)
OAS: 443101(GRM1)
SSC: 100625610(GRM1)
CFR: 102523079(GRM1)
CDK: 105092074(GRM1)
LVE: 103085587(GRM1)
OOR: 101286756(GRM1)
DLE: 111166689(GRM1)
PCAD: 102978027(GRM1)
ECB: 100060603(GRM1)
EPZ: 103564725(GRM1)
EAI: 106837226(GRM1)
HAI: 109380898(GRM1)
DRO: 112297397(GRM1)
PALE: 102878912(GRM1)
RAY: 107518526(GRM1)
TMU: 101357087
MDO: 100026724(GRM1)
SHR: 100919608(GRM1)
PCW: 110208519(GRM1)
OAA: 100075372(GRM1)
GGA: 421614(GRM1)
MGP: 100540165(GRM1)
CJO: 107311576(GRM1)
APLA: 101803914(GRM1)
ACYG: 106034294(GRM1)
TGU: 751999(GRM1)
LSR: 110468842(GRM1)
SCAN: 103818453(GRM1)
GFR: 102038278(GRM1)
FAB: 101807135(GRM1)
PHI: 102107527(GRM1)
PMAJ: 107202384(GRM1)
CCAE: 111927059(GRM1)
CCW: 104689210(GRM1)
FPG: 101920400(GRM1)
CLV: 102091439(GRM1)
EGZ: 104133563(GRM1)
NNI: 104013781(GRM1)
PADL: 103918143(GRM1)
AAM: 106486778(GRM1)
ASN: 102378290(GRM1)
AMJ: 102563002(GRM1)
PSS: 102460135(GRM1)
CMY: 102932638(GRM1)
CPIC: 101940955(GRM1)
ACS: 100564433(grm1)
PVT: 110088369(GRM1)
TSR: 106543622(GRM1)
PMUA: 114594222(GRM1)
XTR: 100495945(grm1)
NPR: 108787741(GRM1)
DRE: 100150246(grm1b) 555576(grm1a)
CCAR: 109108722
IPU: 108270069(grm1) 108279026
TRU: 101065368(grm1) 101071408
LCO: 104929400 104934310(grm1)
MZE: 101467938 101483242(grm1)
ONL: 100697502 100701745(grm1)
OLA: 101165118(grm1) 101170976
XMA: 102224833(grm1) 102226132
XCO: 114134732 114158865(grm1)
PRET: 103457526(grm1) 103458356
CVG: 107086032(grm1) 107091581
NFU: 107377567(grm1) 107391977
KMR: 108239081(grm1b) 108240124(grm1a)
ALIM: 106519782(grm1)
AOCE: 111572587(grm1) 111578565
CSEM: 103380242 103381085(grm1)
POV: 109636085(grm1)
SDU: 111225349 111240111(grm1)
SLAL: 111655604(grm1) 111665818
HCQ: 109527746(grm1)
BPEC: 110155964(grm1)
MALB: 109954042(grm1)
SFM: 108923354
PKI: 111857957
LCM: 102359097(GRM1)
CMK: 103179290(grm1)
BFO: 118422754
NVI: 100118400
HMG: 100206629
 » show all
Reference
PMID:1847995
  Authors
Masu M, Tanabe Y, Tsuchida K, Shigemoto R, Nakanishi S
  Title
Sequence and expression of a metabotropic glutamate receptor.
  Journal
Nature 349:760-5 (1991)
DOI:10.1038/349760a0
  Sequence
[rno:24414]

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