KEGG   ORTHOLOGY: K04701
Entry
K04701                      KO                                     
Symbol
CISH
Name
cytokine inducible SH2-containing protein
Pathway
map04630  JAK-STAT signaling pathway
map04917  Prolactin signaling pathway
Disease
H00342  Tuberculosis
H00361  Malaria
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K04701  CISH; cytokine inducible SH2-containing protein
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K04701  CISH; cytokine inducible SH2-containing protein
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K04701  CISH; cytokine inducible SH2-containing protein
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul5 complex
    Target recognizing subunit
     K04701  CISH; cytokine inducible SH2-containing protein
Genes
HSA: 1154(CISH)
PTR: 470819(CISH)
PPS: 100969527(CISH)
GGO: 101130716(CISH)
PON: 100450314(CISH)
NLE: 100596920(CISH)
HMH: 116473433(CISH)
MCC: 701456(CISH)
MCF: 102119548(CISH)
MTHB: 126948727
MNI: 105480497(CISH)
CSAB: 103227682(CISH)
CATY: 105573730(CISH)
PANU: 101001596(CISH)
TGE: 112618655(CISH)
MLEU: 105548967(CISH)
RRO: 104666850(CISH)
RBB: 108526942(CISH)
TFN: 117082226(CISH)
PTEH: 111555456(CISH)
CANG: 105509659(CISH)
CJC: 100411002(CISH)
SBQ: 101035612(CISH)
CIMI: 108283201(CISH)
CSYR: 103255447(CISH)
MMUR: 105875011(CISH)
LCAT: 123623229(CISH)
PCOQ: 105812481(CISH)
OGA: 100940354(CISH)
MMU: 12700(Cish)
MCAL: 110301241(Cish)
MPAH: 110327918(Cish)
RNO: 83681(Cish)
MCOC: 116073298(Cish)
ANU: 117725040(Cish)
MUN: 110564569(Cish)
CGE: 100774955(Cish)
MAUA: 101826626(Cish)
PROB: 127237081(Cish)
PLEU: 114710992(Cish)
MORG: 121464124(Cish)
MFOT: 126500020
AAMP: 119809635(Cish)
NGI: 103750144(Cish)
HGL: 101716746(Cish)
CPOC: 100719354(Cish)
CCAN: 109693222(Cish)
DORD: 105994625(Cish)
DSP: 122095672(Cish)
PLOP: 125342423(Cish)
NCAR: 124992896
MMMA: 107143438(Cish)
OCU: 100341861
OPI: 101535444(CISH)
TUP: 102478454(CISH)
GVR: 103593695(CISH)
CFA: 484757(CISH)
CLUD: 112665840(CISH)
VVP: 112910875(CISH)
VLG: 121496183(CISH)
NPO: 129521653(CISH)
AML: 100484615(CISH)
UMR: 103675084(CISH)
UAH: 113256921(CISH)
UAR: 123798704(CISH)
ELK: 111144142
LLV: 125079528
MPUF: 101678788(CISH)
MNP: 132011366(CISH)
MLK: 131823978(CISH)
NVS: 122909387(CISH)
ORO: 101373807(CISH)
EJU: 114225052(CISH)
ZCA: 113918702(CISH)
MLX: 118005291(CISH)
NSU: 110577609(CISH)
LWW: 102733945(CISH)
FCA: 101096550(CISH)
PYU: 121011251(CISH)
PCOO: 112852736(CISH)
PBG: 122487269(CISH)
PVIV: 125160179(CISH)
LRUF: 124523156
PTG: 102970540(CISH)
PPAD: 109247857(CISH)
PUC: 125929407
AJU: 106979200
HHV: 120229183(CISH)
BTA: 616753(CISH)
BOM: 102283657(CISH)
BIU: 109576359(CISH)
BBUB: 102394975(CISH)
BBIS: 104997168(CISH)
CHX: 102169142(CISH)
OAS: 101119259(CISH)
BTAX: 128049458(CISH)
ODA: 120868318(CISH)
CCAD: 122424867(CISH)
MBEZ: 129547875(CISH)
SSC: 100518866(CISH)
CFR: 102518551(CISH)
CBAI: 105080217(CISH)
CDK: 105087299(CISH)
VPC: 102525393(CISH)
BACU: 103001242(CISH)
BMUS: 118903115(CISH)
LVE: 103077441(CISH)
OOR: 101281568(CISH)
DLE: 111174349(CISH)
PCAD: 102992405(CISH)
PSIU: 116762566(CISH)
NASI: 112400818(CISH)
ECB: 100061510(CISH)
EPZ: 103559273(CISH)
EAI: 106830740(CISH)
MYB: 102241719(CISH)
MYD: 102757635(CISH)
MMYO: 118668438(CISH)
MLF: 102436656(CISH)
PKL: 118715631(CISH)
EFUS: 103298501(CISH)
MNA: 107540176(CISH)
DRO: 112309649(CISH)
SHON: 118989434(CISH)
AJM: 119036694(CISH)
PDIC: 114501715(CISH)
PHAS: 123830573(CISH)
MMF: 118633612(CISH)
PPAM: 129087772(CISH)
HAI: 109375308(CISH)
RFQ: 117036541(CISH)
PALE: 102881891(CISH)
PGIG: 120582398(CISH)
PVP: 105295182(CISH)
RAY: 107504125(CISH)
MJV: 108402880(CISH)
TOD: 119260750(CISH)
SARA: 101557186(CISH)
LAV: 100666357(CISH)
TMU: 101345926
ETF: 101638119(CISH)
DNM: 101442117(CISH)
MDO: 100028873(CISH)
GAS: 123247106(CISH)
SHR: 100926286(CISH)
AFZ: 127554338
PCW: 110216971(CISH)
OAA: 100082866(CISH)
GGA: 395335(CISH)
PCOC: 116232303(CISH)
MGP: 100545029(CISH)
CJO: 107319571(CISH)
TPAI: 128078389(CISH)
LMUT: 125698560(CISH)
NMEL: 110404944(CISH)
APLA: 101802505(CISH)
ACYG: 106042818(CISH)
CATA: 118248285(CISH)
AFUL: 116493025(CISH)
TGU: 100222098(CISH)
LSR: 110469925(CISH)
SCAN: 103816964(CISH)
PMOA: 120495681(CISH)
OTC: 121347213(CISH)
PRUF: 121350945(CISH)
GFR: 102045133(CISH)
FAB: 101806369(CISH)
OMA: 130258211(CISH)
PHI: 102113991(CISH)
PMAJ: 107210188(CISH)
CCAE: 111935196(CISH)
CCW: 104683209(CISH)
CBRC: 103614253(CISH)
ETL: 114058784(CISH)
ZAB: 102073006(CISH)
ACHL: 103798488(CISH)
SVG: 106849232(CISH)
MMEA: 130574673(CISH)
HRT: 120758280(CISH)
FPG: 101918904(CISH)
FCH: 102048702(CISH)
CLV: 102094074(CISH)
EGZ: 104126763(CISH)
NNI: 104008715(CISH)
PCRI: 104028138(CISH)
PLET: 104619444(CISH)
EHS: 104504777(CISH)
PCAO: 104041963(CISH)
ACUN: 113484832(CISH)
TALA: 104356449(CISH)
PADL: 103915069(CISH)
AFOR: 103898263(CISH)
ACHC: 115333425(CISH)
HALD: 104315951(CISH)
HLE: 104828109(CISH)
AGEN: 126049867
GCL: 127021399
CCRI: 104156419(CISH)
CSTI: 104559388(CISH)
CMAC: 104482232(CISH)
MUI: 104535138(CISH)
BREG: 104639699(CISH)
FGA: 104079568(CISH)
GSTE: 104262603(CISH)
LDI: 104353550(CISH)
MNB: 103778678(CISH)
OHA: 104334108(CISH)
NNT: 104400813(CISH)
SHAB: 115614445(CISH)
DPUB: 104300391(CISH)
PGUU: 104459935(CISH)
ACAR: 104521041(CISH)
CPEA: 104388106(CISH)
AVIT: 104276549(CISH)
CVF: 104291948(CISH)
RTD: 128915469(CISH)
CUCA: 104059047(CISH)
TEO: 104373094(CISH)
BRHI: 104502096(CISH)
AAM: 106492167(CISH)
AROW: 112960624(CISH)
NPD: 112949161(CISH)
TGT: 104577184(CISH)
DNE: 112993761(CISH)
SCAM: 104147861(CISH)
ASN: 102381393(CISH)
AMJ: 102564217(CISH)
CPOO: 109318304(CISH)
GGN: 109289205(CISH)
PSS: 102463167(CISH)
CMY: 102941045(CISH)
CCAY: 125639896(CISH)
DCC: 119858358(CISH)
CPIC: 101935327(CISH)
TST: 117880434(CISH)
CABI: 116839681(CISH)
MRV: 120369340(CISH)
ACS: 100552117(cish)
ASAO: 132769145(CISH)
PVT: 110076542(CISH)
SUND: 121921165(CISH)
PBI: 103057754(CISH)
PMUR: 107288554(CISH)
CTIG: 120311075 120318079(CISH)
TSR: 106553420(CISH)
PGUT: 117678782(CISH)
APRI: 131193617(CISH)
PTEX: 113453879(CISH)
NSS: 113415739(CISH)
VKO: 123034198(CISH)
PMUA: 114591547(CISH)
PRAF: 128408166(CISH)
ZVI: 118080597(CISH)
HCG: 128348080(CISH)
GJA: 107123854(CISH)
STOW: 125430263(CISH)
EMC: 129329332(CISH)
XLA: 108714605(cish.L) 108715831(cish.S)
XTR: 100135018(cish)
NPR: 108802833
RTEM: 120944954(CISH)
BBUF: 120979338(CISH)
BGAR: 122922607(CISH)
MUO: 115472280(CISH)
GSH: 117351402(CISH)
DRE: 100136861(cishb) 767678(cish)
SRX: 107712118 107729392 107750261 107753774
SANH: 107656055 107657992 107673597
SGH: 107558886 107567071 107567092 107584452 107600289
CCAR: 109061216 109091345 109091346
CAUA: 113050445 113095628 113111029
CGIB: 127959499 127968141 128015812
PTET: 122347395(cish) 122354269(cishb)
LROH: 127166953(cish) 127173460(cishb)
OMC: 131541955(cish) 131549016(cishb)
PPRM: 120480380(cishb) 120491601(cish)
RKG: 130086699(cishb) 130087460(cish)
MAMB: 125257119(cishb) 125273821(cish)
CIDE: 127514104 127522412
MASI: 127428271 127446565 127448629
TROS: 130556776(cish) 130571640(cishb)
TDW: 130410745(cishb) 130424654(cish)
MANU: 129427654(cishb) 129450121(cish)
IPU: 108254847 108272001(cish)
IFU: 128614690(cish) 128625311
PHYP: 113536093 113539429
SMEO: 124385423(cish) 124402180
TFD: 113642910(cish) 113661825
TVC: 132838293 132844480(cish)
AMEX: 103024017 103027028(cish) 111191435
CMAO: 118799834 118808348(cish)
EEE: 113568246 113576031(cish) 113586897
CHAR: 105895891(cish) 105904920
TRU: 100135423(socs8) 100144307(cish)
TFS: 130523843 130524519
TNG: GSTEN00027367G001 GSTEN00027530G001
LCO: 104930954(cish) 104933315
NCC: 104949001 104951549(cish)
TBEN: 117489624(cish) 117490004
CGOB: 115007978(cish) 115008049
PGEO: 117446323(cish) 117446481
GACU: 117548201 117551070
EMAC: 134882171 134882624(cisha)
ELY: 117256460 117257501(cish)
EFO: 125893190(cish) 125895787
PLEP: 121950456 121958112(cish)
SLUC: 116051282(cish)
ECRA: 117943000(cish) 117943275
ESP: 116687698 116688103(cish)
PFLV: 114553874 114554113(cish)
GAT: 100190868(cish) 100190872(socs8)
PPUG: 119194092(cish) 119229898
AFB: 129105475 129105516(cish)
CLUM: 117730565(cish) 117730675
PSWI: 130207959(cish) 130208151
MSAM: 119886190 119886225
SCHU: 122885180(cish)
CUD: 121507389(cish) 121529312
ALAT: 119020838 119021058
MZE: 101481038(cish) 101485240
ONL: 100702013(cish) 100710219
OAU: 116333855 116334233
OLA: 100144373(cish) 100144389(socs8)
OML: 112144642 112144860
CSAI: 133449360 133449400(cish)
XMA: 102222759(cish) 102233161
XCO: 114135650(cish) 114135713
XHE: 116710683(cish) 116710755
PRET: 103464501(cish) 103465140
PFOR: 103136881(cish) 103138290
PLAI: 106957313(cish) 106960332
PMEI: 106918067 106924983(cish)
GAF: 122834281(cish) 122834582
PPRL: 129356273 129356623(cish)
CVG: 107089349(cish) 107103109
CTUL: 119780030 119780143(cish)
GMU: 124856243 124856652
NFU: 107385101 107385234(cish)
KMR: 108231178 108235640
ALIM: 106516178 106536130
NWH: 119411805(cish) 119411907
AOCE: 111568126 111585425(cish)
MCEP: 125006620 125006644
CSEM: 103385658(cish) 103385833
POV: 109638538 109638621(cish)
SSEN: 122767780 122768570(cish)
HHIP: 117761664 117761848
HSP: 118104522 118105211
SMAU: 118309284 118309432
LCF: 108886516 108899166
SDU: 111222937(cish) 111222951
SLAL: 111653829(cish) 111660810
XGL: 120782918 120807292
HCQ: 109510640(cish) 109522386
SSCV: 125977277 125977765
SBIA: 133506952 133508115
PEE: 133408778 133408988(cish)
PTAO: 133483271 133483328(cish)
BPEC: 110168641(cish)
MALB: 109954331 109959039(cish)
BSPL: 114855729(cish) 114855840
SJO: 128355101(cish) 128356193
SASA: 100196184(cish) 106565139 106565979(CISH)
STRU: 115150936 115207497 115208180
OTW: 112244835 112247315(cish) 112254297 112254893
OMY: 100329195(cish) 110494652 110494984 110528417
OGO: 124002851 124003423 124020896 124028398
ONE: 115136492 115142988 115143437 115143653
OKI: 109891620 109898581 109899569
OKE: 118374135 118388296 118389537 118400016
SALP: 111963253 111969793 111970002 111970398
SNH: 120059050 120063366 120064625 120064933
CCLU: 121574854(cish) 121575443 121578106 121578416
ELS: 105016856 105025413(cish)
SFM: 108940271(cish)
PKI: 111855858 111860003
AANG: 118207848(cish)
PSPA: 121298115 121329275
ARUT: 117411999 117963484
PSEX: 120540445
LCM: 102347327(CISH)
CMK: 103176646(cish)
RTP: 109927413
CPLA: 122558831
HOC: 132822065
LERI: 129704703
LRJ: 133355462
SKO: 100374617
SOY: 115878556
ATD: 109608386
CSET: 123317130
AGB: 108903483
LDC: 111503373
NVL: 108557029
APLN: 108736582
PPYR: 116161899 116178324
OTU: 111426679
API: 100572348
DVT: 126893970 126909821
DCI: 103505153
CLEC: 106673777
HVI: 124354412
MQU: 128999973 129000003
TPAL: 117649715
ZNE: 110839114
FCD: 110860028
PCLA: 123749939
PTRU: 123520504
PPOI: 119091070
UDV: 129221766
LGI: LOTGIDRAFT_78096
GAE: 121379079
HRF: 124137251
HRJ: 124282818
OED: 125646446
MYI: 110463855
OSN: 115223229
 » show all
Reference
PMID:12076535
  Authors
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.
  Title
The SOCS box: a tale of destruction and degradation.
  Journal
Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6
  Sequence
[hsa:1154]

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Disease (2)   
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Gene (741)   
   KEGG GENES (560)   
   KEGG MGENES (41)   
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