KEGG   ORTHOLOGY: K04710
Entry
K04710                      KO                                     

Name
CERS1, LASS1
Definition
sphingoid base N-stearoyltransferase [EC:2.3.1.299]
Pathway
ko00600  Sphingolipid metabolism
ko01100  Metabolic pathways
ko04071  Sphingolipid signaling pathway
Module
M00094  Ceramide biosynthesis
M00099  Sphingosine biosynthesis
Disease
H00810  Progressive myoclonic epilepsy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K04710  CERS1, LASS1; sphingoid base N-stearoyltransferase
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K04710  CERS1, LASS1; sphingoid base N-stearoyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.299  sphingoid base N-stearoyltransferase
     K04710  CERS1, LASS1; sphingoid base N-stearoyltransferase
Other DBs
RN: R01496 R06517
GO: 0050291
Genes
HSA: 10715(CERS1)
PTR: 468773(CERS1)
PPS: 100968130(CERS1)
GGO: 109024075(CERS1)
PON: 100447528(CERS1)
NLE: 115830373(CERS1)
MCC: 106994665(CERS1)
MCF: 107128159(CERS1)
CSAB: 103234393(CERS1)
RRO: 104680635(CERS1)
RBB: 108515632(CERS1)
CJC: 103789832(CERS1)
SBQ: 101041201(CERS1)
MMU: 93898(Cers1)
MCAL: 110299631(Cers1)
MPAH: 110336871(Cers1)
RNO: 290658(Cers1)
MUN: 110549168(Cers1)
CGE: 100765511(Cers1)
NGI: 103726856(Cers1)
HGL: 101705418(Cers1)
CCAN: 109684934(Cers1)
TUP: 102475765(CERS1)
CFA: 609789(CERS1)
VVP: 112913073(CERS1)
AML: 100478537(CERS1)
UMR: 103675149(CERS1)
UAH: 113256735(CERS1)
ORO: 101380694(CERS1)
ELK: 111144244
FCA: 101089084(CERS1)
PTG: 102961418(CERS1)
PPAD: 109247644(CERS1)
AJU: 106969135(CERS1)
BTA: 615296(CERS1)
BOM: 102269743(CERS1)
BIU: 109560813(CERS1)
BBUB: 102401086(CERS1)
CHX: 102189571(CERS1)
OAS: 101107095(CERS1)
SSC: 100525450(CERS1)
CFR: 102507344(CERS1)
CDK: 105101886(CERS1)
BACU: 103003098(CERS1)
LVE: 103091398(CERS1)
OOR: 101273399(CERS1)
DLE: 111166519(CERS1)
PCAD: 102977839(CERS1)
ECB: 100069594(CERS1)
EAI: 106846409(CERS1)
MYB: 102249252(CERS1)
MYD: 102769776(CERS1)
MNA: 107535343(CERS1)
HAI: 109382399(CERS1)
DRO: 112305215(CERS1)
PALE: 102885878(CERS1)
RAY: 107503723(CERS1)
MJV: 108406026(CERS1)
LAV: 100667031(CERS1)
TMU: 101347699
MDO: 100016686(CERS1)
SHR: 100934844(CERS1)
PCW: 110223377(CERS1)
OAA: 100078502(CERS1)
GGA: 420118(CERS1)
MGP: 100547857(CERS1)
CJO: 107325354(CERS1)
NMEL: 110388870(CERS1)
APLA: 101804779(CERS1)
ACYG: 106047960(CERS1)
TGU: 100230030(CERS1)
LSR: 110478333(CERS1)
SCAN: 108963610(CERS1)
GFR: 102035945(CERS1)
PHI: 102107684(CERS1)
CCW: 104697388(CERS1)
ETL: 114071345(CERS1)
FPG: 101923637(CERS1)
FCH: 102046386(CERS1)
CLV: 102098532(CERS1)
EGZ: 104129784(CERS1)
NNI: 104013688(CERS1)
ACUN: 113489365(CERS1)
PADL: 103923274(CERS1)
ASN: 102384359(CERS1)
AMJ: 102563913(CERS1)
CMY: 102935204(CERS1)
CPIC: 103305686(CERS1)
PVT: 110072532(CERS1)
PBI: 103067620(CERS1)
PMUR: 107282886(CERS1)
TSR: 106543865(CERS1)
PMUA: 114588648(CERS1)
GJA: 107105635(CERS1)
XLA: 108703695(cers1.S) 108713514(cers1.L)
XTR: 100485129(cers1)
NPR: 108796582(CERS1)
DRE: 568169(cers1)
SRX: 107727553(cers1)
SGH: 107549387(cers1) 107566364
CCAR: 109073214
IPU: 100528482(cers1)
PHYP: 113536501(cers1)
AMEX: 103043497(cers1)
EEE: 113577802(cers1)
TRU: 101079773(cers1)
LCO: 104918072(cers1)
MZE: 101468648(cers1)
ONL: 100703783(cers1)
OLA: 101166466(cers1)
XMA: 102238205(cers1)
XCO: 114150769(cers1)
PRET: 103464102(cers1)
CVG: 107101216(cers1)
NFU: 107393118(cers1)
KMR: 108230660(cers1)
ALIM: 106511910(cers1)
AOCE: 111571325(cers1)
CSEM: 103393467(cers1)
POV: 109625614(cers1)
SDU: 111216491(cers1)
SLAL: 111650208(cers1)
HCQ: 109516892(cers1)
BPEC: 110160186 110160210(cers1)
MALB: 109967431(cers1)
ELS: 105011446(cers1)
LCM: 102351990(CERS1)
CMK: 103181964(cers1)
BFO: 118411284
SPU: 592336
TUT: 107366570
CSCU: 111612809
CEL: CELE_Y6B3B.10(lagr-1)
CBR: CBG13635(Cbr-lagr-1)
LAK: 106174562
SHX: MS3_08053
NVE: 5522174
EPA: 110240089
ADF: 107340796
AMIL: 114966382
DGT: 114522828
 » show all
Reference
  Authors
Venkataraman K, Riebeling C, Bodennec J, Riezman H, Allegood JC, Sullards MC, Merrill AH Jr, Futerman AH
  Title
Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells.
  Journal
J Biol Chem 277:35642-9 (2002)
DOI:10.1074/jbc.M205211200
  Sequence
[hsa:10715]

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