KEGG   ORTHOLOGY: K04722
Entry
K04722                      KO                                     
Symbol
TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2
Name
tumor necrosis factor receptor superfamily member 10A/B
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04115  p53 signaling pathway
map04210  Apoptosis
map04217  Necroptosis
map04650  Natural killer cell mediated cytotoxicity
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
map05164  Influenza A
map05417  Lipid and atherosclerosis
Disease
H02610  Head and neck squamous cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
   04217 Necroptosis
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
   04115 p53 signaling pathway
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
   05132 Salmonella infection
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
   04090 CD molecules
    K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
Cytokine receptors [BR:ko04050]
 Tumor necrosis factor receptors
  TNF receptor superfamily
   K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
CD molecules [BR:ko04090]
 Proteins
  K04722  CD261, TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a
  K04722  CD262, TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b
Other DBs
GO: 0005031 0045569
Genes
HSA: 8795(TNFRSF10B) 8797(TNFRSF10A)
PTR: 742898(TNFRSF10B) 743159(TNFRSF10A)
PPS: 100971044(TNFRSF10A) 100973227(TNFRSF10B)
GGO: 101141415(TNFRSF10B) 101146659(TNFRSF10A)
PON: 100460763(TNFRSF10B) 100461502(TNFRSF10A)
PPYG: 129042257(TNFRSF10A) 129042343(TNFRSF10B)
NLE: 100602881(TNFRSF10A) 105740159(TNFRSF10B)
HMH: 116461997(TNFRSF10B) 116462001(TNFRSF10A)
MCC: 716650(TNFRSF10B) 716826(TNFRSF10A)
MCF: 102133727(TNFRSF10B) 102139560(TNFRSF10A)
MNI: 105482067(TNFRSF10B) 105482149
CSAB: 103215469(TNFRSF10B) 103215472(TNFRSF10A)
CATY: 105579211(TNFRSF10A) 105579216(TNFRSF10B)
PANU: 101002483(TNFRSF10B) 101004108(TNFRSF10A)
TGE: 112630107(TNFRSF10A) 112630735(TNFRSF10B)
MLEU: 105531023(TNFRSF10B) 105531054(TNFRSF10A)
RRO: 104663979(TNFRSF10B) 104663984(TNFRSF10A)
RBB: 108537955(TNFRSF10A) 108540791(TNFRSF10B)
TFN: 117093403(TNFRSF10A) 117093430(TNFRSF10B)
PTEH: 111545697(TNFRSF10B) 111545701(TNFRSF10A)
CANG: 105510193(TNFRSF10A) 105510195(TNFRSF10B)
CJC: 100395977(TNFRSF10A) 100397065 100397442(TNFRSF10B)
SBQ: 101042934(TNFRSF10B) 101045196(TNFRSF10A)
CIMI: 108318569(TNFRSF10A) 108318570(TNFRSF10B)
ANAN: 105705302(TNFRSF10A) 105705409(TNFRSF10B)
OGA: 100960488
MMU: 21933(Tnfrsf10b)
MCAL: 110309833
MPAH: 110325978(Tnfrsf10b)
MCOC: 116084931
ANU: 117704975
MUN: 110557077
CGE: 100770489
MAUA: 101833926
PROB: 127230045
PLEU: 114702690
AAMP: 119799946
NGI: 108491686
HGL: 101697353(Tnfrsf10b)
CPOC: 101787877
DORD: 105999403
DSP: 122123517
NCAR: 124983904
MMMA: 107153920
GVR: 103592524(TNFRSF10A) 103609839
CFA: 100688321
VLG: 121471437
NPO: 129501496
AML: 105235183
UMR: 103671065
ELK: 111150032
MNP: 132017102
MLK: 131817431
NVS: 122913256
EJU: 114220186
ZCA: 113915274
LWW: 102738560
FCA: 105261012
PYU: 121023950
PCOO: 112852058
PBG: 122484112
PVIV: 125176960
LRUF: 124505594
PTG: 102952670
PPAD: 109246925
PUC: 125911526
AJU: 106982854
HHV: 120233928
BIU: 109563119
MBEZ: 129556896
LVE: 103075576 103076248 103089274(TNFRSF10A)
OOR: 101271509
DLE: 111185435(TNFRSF10A) 111185436
NASI: 112401433 112401434(TNFRSF10A)
ECB: 100057812(TNFRSF10B) 102149226 102150834
EPZ: 103552761(TNFRSF10B)
MYB: 102253175(TNFRSF10B)
MYD: 102751782(TNFRSF10B)
MMYO: 118648977 118649099 118658901(TNFRSF10B)
MLF: 102424229(TNFRSF10A)
EFUS: 103295138(TNFRSF10B)
SHON: 118975062
PDIC: 114503748
PHAS: 123828317
MMF: 118643808
HAI: 109372325(TNFRSF10A) 109389286
PALE: 102887459(TNFRSF10B)
PVP: 105296657(TNFRSF10B)
MJV: 108393208
TOD: 119233979(TNFRSF10A)
SARA: 101537204(TNFRSF10B)
SETR: 126004388
TMU: 101348450
DNM: 101438083(TNFRSF10B)
MDO: 103100524(TNFRSF10A)
GAS: 123233411(TNFRSF10A)
SHR: 105749071
TVP: 118841232
GGA: 373904(TNFRSF10B)
MGP: 100539605 664712(TNFRSF10B)
TPAI: 128090036
LMUT: 125685252
CATA: 118255990
OTC: 121346728
PRUF: 121365967
FAB: 101816790(TNFRSF10A) 101820140
OMA: 130261979
CBRC: 103614954
ETL: 114069860
ZAB: 102071440
ZLE: 135456843(TNFRSF10B)
SVG: 106863437(TNFRSF10B)
MMEA: 130587541
HRT: 120764013
FPG: 101919474(TNFRSF10A)
FCH: 102053169
CLV: 102094994
EGZ: 104123536
NNI: 104019542(TNFRSF10B)
PCRI: 104033452
PLET: 104625522
EHS: 104515400
ACUN: 113488038
TALA: 116959736
AFOR: 103893823
ACHC: 115350118
HLE: 104828839(TNFRSF10B)
AGEN: 126051499
GCL: 127025248
CCRI: 104167180
CMAC: 104485149
BREG: 104632616
FGA: 104076004
GSTE: 104258706(TNFRSF10B)
MNB: 103770535
OHA: 104338557
SHAB: 115618487
DPUB: 104297814
CPEA: 104397222
CVF: 104285668
RTD: 128919617
CUCA: 104068597
TEO: 104371771
BRHI: 104497169
NPD: 112949785(TNFRSF10B)
SCAM: 104147536
ASN: 102368783 102378076(TNFRSF10B)
AMJ: 102562497(TNFRSFA) 106737553(TNFRSF10B)
ACS: 100559769 103281217(tnfrsf10b)
ASAO: 132782492
SUND: 121935055
VKO: 123026999
GJA: 107107289(TNFRSF10B) 107124146
STOW: 125441986
EMC: 129325179 129342362(TNFRSF10B)
XLA: 404688(tnfrsf10b.L)
XTR: 448240(tnfrsf10b)
RTEM: 120917044
BBUF: 120981141
BGAR: 122920244
MUO: 115469421
GSH: 117362256
DRE: 373093(hdr)
CGIB: 127958284
PTET: 122345579(hdr)
LROH: 127164951(hdr)
OMC: 131540649(hdr)
PPRM: 120470427(hdr)
MAMB: 125266505(hdr)
CIDE: 127512245
MASI: 127420274
TROS: 130567379(hdr)
TDW: 130419415(hdr)
MANU: 129440098(hdr)
IPU: 108255678(hdr) 108279174(tnfrsfa)
IFU: 128625619(hdr)
SMEO: 124380370(hdr)
TFD: 113639514(hdr)
TVC: 132855067(hdr)
TRN: 134335369(hdr)
AMEX: 103025853(tnfrsfa) 103030935(hdr)
CMAO: 118827384(hdr)
CHAR: 105889954(hdr)
TFS: 130517329(tnfrsfa) 130526430(hdr)
NCC: 104946837
TBEN: 117476599(tnfrsfa) 117489094
PGEO: 117444879 117456180(tnfrsfa)
GACU: 117538258 117562217(tnfrsfa)
EMAC: 134868224(tnfrsfa)
ELY: 117253214(hdr) 117269833(tnfrsfa)
EFO: 125890552(hdr) 125905745(tnfrsfa)
PLEP: 121944916(hdr) 121959704(tnfrsfa)
SLUC: 116047668(hdr) 116063023(tnfrsfa)
ECRA: 117944776(hdr) 117959828(tnfrsfa)
GAT: 120831152(hdr) 120831568(tnfrsfa)
PPUG: 119225593(hdr) 119227063
CLUM: 117735912(hdr) 117740781(tnfrsfa)
PSWI: 130196354 130205306(tnfrsfa)
MSAM: 119892131(hdr) 119914185(tnfrsfa) 119918688
SCHU: 122865611 122876352(hdr)
CUD: 121510319(hdr) 121525059(tnfrsfa)
ALAT: 119019251(hdr) 119030076(tnfrsfa)
OAU: 116310481(tnfrsfa) 116321102(hdr)
OML: 112148678(hdr) 112163478
CSAI: 133451456(hdr) 133455098(tnfrsfa)
GAF: 122827092(hdr) 122847240(tnfrsfa)
PPRL: 129351621(hdr) 129374293(tnfrsfa)
CTUL: 119773219(tnfrsfa) 119791261
GMU: 124872613 124877166(hdr)
KMR: 108242614(tnfrsfa) 108247039
NWH: 119413681 119424839(tnfrsfa)
MCEP: 124996629
SSEN: 122758445(tnfrsfa) 122770034(hdr)
HHIP: 117768556(hdr) 117768557 117771545(tnfrsfa)
HSP: 118115530(hdr) 118125828(tnfrsfa)
PPLT: 128424617(tnfrsfa) 128438255(hdr)
SMAU: 118284772(tnfrsfa) 118314143(hdr)
LCF: 108878624(hdr) 108895430(tnfrsfa)
XGL: 120805095(hdr) 120806581(tnfrsfa)
SBIA: 133490628 133499378(hdr)
PEE: 133400324(hdr) 133414193(tnfrsfa)
PTAO: 133474766(hdr) 133490291(tnfrsfa)
BSPL: 114845540 114866892(tnfrsfa)
SJO: 128364981(hdr) 128380553(tnfrsfa)
AANG: 118206564(hdr) 118213458
LOC: 102683981
ARUT: 117966494
HOC: 132826121
PMRN: 116956968
HRF: 124115064
HRJ: 124281777
CANU: 128160461
MYI: 110460904
PMAX: 117344407
ADF: 107358732
XEN: 124436834
 » show all
Reference
PMID:9285725
  Authors
Screaton GR, Mongkolsapaya J, Xu XN, Cowper AE, McMichael AJ, Bell JI
  Title
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL.
  Journal
Curr Biol 7:693-6 (1997)
DOI:10.1016/S0960-9822(06)00297-1
  Sequence
[hsa:8795]
Reference
PMID:9082980
  Authors
Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM
  Title
The receptor for the cytotoxic ligand TRAIL.
  Journal
Science 276:111-3 (1997)
DOI:10.1126/science.276.5309.111
  Sequence
[hsa:8797]

DBGET integrated database retrieval system