KEGG   ORTHOLOGY: K04729Help
Entry
K04729                      KO                                     

Name
MYD88
Definition
myeloid differentiation primary response protein MyD88
Pathway
ko04010  MAPK signaling pathway
ko04064  NF-kappa B signaling pathway
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05143  African trypanosomiasis
ko05144  Malaria
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05168  Herpes simplex infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
Module
M00686  Toll-like receptor signaling
Disease
H00721  Pyogenic bacterial infections, recurrent, due to MYD88 deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   04064 NF-kappa B signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   04624 Toll and Imd signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   04621 NOD-like receptor signaling pathway
    K04729  MYD88; myeloid differentiation primary response protein MyD88
 09160 Human Diseases
  09171 Infectious diseases: Bacterial
   05132 Salmonella infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05133 Pertussis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05134 Legionellosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05152 Tuberculosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
  09172 Infectious diseases: Viral
   05170 Human immunodeficiency virus 1 infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05162 Measles
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05164 Influenza A
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05161 Hepatitis B
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05168 Herpes simplex infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05169 Epstein-Barr virus infection
    K04729  MYD88; myeloid differentiation primary response protein MyD88
  09174 Infectious diseases: Parasitic
   05144 Malaria
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05145 Toxoplasmosis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05140 Leishmaniasis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05142 Chagas disease (American trypanosomiasis)
    K04729  MYD88; myeloid differentiation primary response protein MyD88
   05143 African trypanosomiasis
    K04729  MYD88; myeloid differentiation primary response protein MyD88
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K04729  MYD88; myeloid differentiation primary response protein MyD88
BRITE hierarchy
Genes
HSA: 4615(MYD88)
PTR: 460269(MYD88)
PPS: 100996159(MYD88)
PON: 100460593(MYD88)
NLE: 100598173(MYD88)
MCC: 696494(MYD88)
MCF: 101866832(MYD88)
CSAB: 103221064(MYD88)
RRO: 104657448(MYD88)
RBB: 108512239(MYD88)
CJC: 100413151(MYD88)
SBQ: 101052794(MYD88)
MMU: 17874(Myd88)
RNO: 301059(Myd88)
CGE: 100775060(Myd88)
NGI: 103744662(Myd88)
HGL: 101712637(Myd88)
CCAN: 109684529(Myd88)
OCU: 100340811(MYD88)
TUP: 102499350(MYD88)
CFA: 477024(MYD88)
AML: 100479307(MYD88)
UMR: 103680724(MYD88)
ORO: 101363951(MYD88)
FCA: 101087092(MYD88)
PTG: 102952059(MYD88)
AJU: 106966692(MYD88)
BTA: 444881(MYD88)
BOM: 102279944(MYD88)
BIU: 109576356(MYD88)
PHD: 102319871(MYD88)
CHX: 102174883(MYD88)
OAS: 678682(MYD88)
SSC: 396646(MYD88)
CFR: 102506575(MYD88)
CDK: 105090692(MYD88)
BACU: 103011989(MYD88)
LVE: 103088205(MYD88)
OOR: 101278425(MYD88)
ECB: 100053940(MYD88)
EPZ: 103557961(MYD88)
EAI: 106834265(MYD88)
MYB: 102247438(MYD88)
MYD: 107183283(MYD88)
HAI: 109393491(MYD88)
RSS: 109445339(MYD88)
PALE: 102890488(MYD88)
LAV: 100659447(MYD88)
TMU: 101341326
SHR: 100927751(MYD88)
OAA: 100077067(MYD88)
GGA: 420420(MYD88)
MGP: 100541304(MYD88)
CJO: 107308786(MYD88)
APLA: 101797621(MYD88)
ACYG: 106036798(MYD88)
TGU: 100223638(MYD88)
SCAN: 103813055(MYD88)
GFR: 102044578(MYD88)
FAB: 101805645(MYD88)
PHI: 102100550(MYD88)
PMAJ: 107200823(MYD88)
CCAE: 111925454(MYD88)
CCW: 104686502(MYD88)
FPG: 101922907(MYD88)
FCH: 102049997(MYD88)
CLV: 102087774(MYD88)
EGZ: 104130985(MYD88)
NNI: 104021773(MYD88)
ACUN: 113476914(MYD88)
AAM: 106490262
ASN: 102372553(MYD88)
AMJ: 102560312(MYD88)
PSS: 102454616(MYD88)
CMY: 102935478(MYD88)
CPIC: 101944305(MYD88)
ACS: 100561767(myd88)
PVT: 110085835(MYD88)
PBI: 103066844(MYD88)
PMUR: 107303333(MYD88)
GJA: 107116437(MYD88)
XLA: 394321(myd88.L) 734302(myd88.S)
XTR: 549591(myd88)
NPR: 108784626(MYD88)
DRE: 403145(myd88)
SANH: 107678069(myd88) 107701636
SGH: 107584943 107591285(myd88)
CCAR: 109045652 109049860(myd88)
IPU: 100305041(myd88)
PHYP: 113541356(myd88)
AMEX: 103044166(myd88)
TRU: 100134853(myd88)
LCO: 104937116(myd88)
MZE: 101476408(myd88)
OLA: 101168580(myd88)
XMA: 102234764(myd88)
PRET: 103456564(myd88)
NFU: 107382819(myd88)
KMR: 108230293(myd88)
CSEM: 103377208(myd88)
LCF: 108881704(myd88)
SDU: 111220968
HCQ: 109514064(myd88)
BPEC: 110160924(myd88)
MALB: 109961464(myd88)
SASA: 100169859(myd88)
OTW: 112227606(myd88)
SALP: 112079159(myd88)
ELS: 105007691(myd88)
SFM: 108934019(myd88)
LCM: 102348650(MYD88)
CMK: 103189851(myd88)
CIN: 100179208
SPU: 575081 575153(myd88)
APLC: 110974581
SKO: 100373041(myd88)
DME: Dmel_CG2078(Myd88)
DER: 6540756
DPE: 6592675
DSI: Dsimw501_GD10085(Dsim_GD10085)
DWI: 6639863
MDE: 101901307
AGA: AgaP_AGAP005252(MYD)
AAG: 5569574
AME: 413194
BIM: 100748729
BTER: 100631094
SOC: 105201138
MPHA: 105833799
AEC: 105146388
ACEP: 105627791
PBAR: 105433443
HST: 105184911
DQU: 106741300
CFO: 105256115
PGC: 109859222
OBO: 105286460
PCF: 106786257
NVI: 100118553(Myd88)
MDL: 103571646
TCA: 662213(Kra)
DPA: 109539329
NVL: 108565220
BMOR: 101735950
PMAC: 106718991
PRAP: 110999561
HAW: 110374863
TNL: 113504445
PXY: 105382914
API: 100160335
DNX: 107169682
CLEC: 106662592
ZNE: 110832274
FCD: 110851565
TUT: 107363907
DPTE: 113792353
CRG: 105337632 105342664(Myd88-2) 105342670(Myd88)
OBI: 106879143
LAK: 106177828
EPA: 110232078
HMG: 105846374
AQU: 100616081(Myd88)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9013863
  Authors
Bonnert TP, Garka KE, Parnet P, Sonoda G, Testa JR, Sims JE
  Title
The cloning and characterization of human MyD88: a member of an IL-1 receptor related family.
  Journal
FEBS Lett 402:81-4 (1997)
DOI:10.1016/S0014-5793(96)01506-2
  Sequence
[hsa:4615]

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