KEGG   ORTHOLOGY: K04730Help
Entry
K04730                      KO                                     

Name
IRAK1
Definition
interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
Pathway
ko04010  MAPK signaling pathway
ko04064  NF-kappa B signaling pathway
ko04620  Toll-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko04722  Neurotrophin signaling pathway
ko05130  Pathogenic Escherichia coli infection
ko05133  Pertussis
ko05135  Yersinia infection
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05162  Measles
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   04064 NF-kappa B signaling pathway
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   04624 Toll and Imd signaling pathway
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05135 Yersinia infection
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05133 Pertussis
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05152 Tuberculosis
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05162 Measles
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05161 Hepatitis B
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05168 Herpes simplex virus 1 infection
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05169 Epstein-Barr virus infection
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05140 Leishmaniasis
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
   05142 Chagas disease (American trypanosomiasis)
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04730  IRAK1; interleukin-1 receptor-associated kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K04730  IRAK1; interleukin-1 receptor-associated kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: TKL group
  IRAK family
   K04730  IRAK1; interleukin-1 receptor-associated kinase 1
BRITE hierarchy
Genes
HSA: 3654(IRAK1)
PPS: 100981891(IRAK1)
GGO: 101140803(IRAK1)
PON: 100437883(IRAK1)
NLE: 100588136(IRAK1)
MCC: 699919(IRAK1)
MCF: 102134829(IRAK1)
CSAB: 103232815(IRAK1)
RRO: 104662981(IRAK1)
RBB: 108535063(IRAK1)
CJC: 100414273(IRAK1)
SBQ: 101052342(IRAK1)
MMU: 16179(Irak1)
MCAL: 110286819(Irak1)
MPAH: 110313647(Irak1)
RNO: 363520(Irak1)
MUN: 110566945(Irak1)
CGE: 100773909(Irak1)
NGI: 103731212(Irak1)
HGL: 101699021(Irak1)
CCAN: 109690874(Irak1)
OCU: 100354743(IRAK1)
TUP: 102473549(IRAK1)
CFA: 492247(IRAK1)
VVP: 112911496(IRAK1)
AML: 100484977(IRAK1)
UMR: 103679690(IRAK1)
UAH: 113247859(IRAK1)
ORO: 101382179(IRAK1)
FCA: 101090500(IRAK1)
PPAD: 109259848(IRAK1)
AJU: 113597389(IRAK1)
BTA: 533953(IRAK1)
BOM: 102277837(IRAK1)
BIU: 109555285(IRAK1)
BBUB: 102396505(IRAK1)
CHX: 102177432(IRAK1)
OAS: 101121405(IRAK1)
SSC: 396606(IRAK1)
CFR: 102523767(IRAK1)
CDK: 105098727(IRAK1)
BACU: 102998365(IRAK1)
LVE: 103074326(IRAK1)
OOR: 101280639(IRAK1)
DLE: 111170605(IRAK1)
PCAD: 102980938 112062410(IRAK1)
ECB: 100059262(IRAK1)
EPZ: 103545279(IRAK1)
EAI: 106825607(IRAK1)
MYB: 102245410(IRAK1)
MYD: 102765985(IRAK1)
MNA: 107538794(IRAK1)
HAI: 109394352(IRAK1)
DRO: 112296346(IRAK1)
PALE: 102894152(IRAK1)
RAY: 107517734(IRAK1)
MJV: 108409511(IRAK1)
LAV: 100676181(IRAK1)
TMU: 101350273
MDO: 100029477(IRAK1)
SHR: 100923900(IRAK1)
PCW: 110201533(IRAK1)
OAA: 100077683(IRAK1)
ASN: 102374837(IRAK1)
AMJ: 102575313(IRAK1)
CPIC: 101937579(IRAK1)
ACS: 100563977(irak1)
PVT: 110070853 110078665(IRAK1)
PBI: 103047962(IRAK1)
PMUR: 107284218(IRAK1)
TSR: 106543646(IRAK1)
PMUA: 114587380(IRAK1)
GJA: 107108391(IRAK1)
XTR: 448357(irak1)
NPR: 108790442(IRAK1)
DRE: 569226(irak1)
SRX: 107743109(irak1)
SGH: 107552214(irak1) 107584912
IPU: 108265822(irak1)
PHYP: 113534859(irak1)
AMEX: 103044222(irak1)
EEE: 113575834(irak1)
TRU: 101061773(irak1)
LCO: 104935488
MZE: 101465239(irak1)
ONL: 100703930(irak1)
OLA: 101166698
XMA: 102231075(irak1)
XCO: 114140233
PRET: 108165939
CVG: 107099142(irak1)
NFU: 107391452(irak1)
KMR: 108228236
ALIM: 106511233 106533780(irak1)
AOCE: 111585594(irak1)
CSEM: 103384394(irak1)
POV: 109645801(irak1)
LCF: 108890558(irak1)
SDU: 111235426(irak1)
SLAL: 111654973(irak1)
HCQ: 109529353(irak1)
BPEC: 110154469(irak1)
MALB: 109967881(irak1)
SASA: 106566344
OTW: 112238306
SALP: 112072310
ELS: 105028326(irak1)
SFM: 108934844(irak1)
PKI: 111856149(irak1)
LCM: 102359430(IRAK1)
CMK: 103176741
RTP: 109924573
CIN: 100178324
APLC: 110983679
SKO: 102804873
DME: Dmel_CG5974(pll)
DER: 6554685
DSI: Dsimw501_GD28088(Dsim_GD28088)
DYA: Dyak_GE10573(Dyak_pll)
DSR: 110177377
DPE: 6587716
DMN: 108156651
DWI: 6649819
DAZ: 108620820
DNV: 115564094
DHE: 111597872
MDE: 101891255
AGA: AgaP_AGAP002966(PELLE)
AAG: 5568148
AME: 551608
BIM: 100742650
BTER: 100650697
CCAL: 108629985
OBB: 114874825
SOC: 105198406
MPHA: 105837711
AEC: 105145974
ACEP: 105622228
PBAR: 105429360
VEM: 105563659
HST: 105187682
DQU: 106746948
CFO: 105256733
LHU: 105671849
PGC: 109857111
OBO: 105279707
PCF: 106793407
NVI: 100115010(pll) 100116695
CSOL: 105359643
MDL: 103578198
TCA: 654877(IL-1)
DPA: 109537660
NVL: 108569521
BMOR: 101745667
PMAC: 106717349
PRAP: 110998947
TNL: 113494818
API: 100169297
AGS: 114127916
BTAB: 109039164
CLEC: 106663343
ZNE: 110829083
FCD: 110858699
PVM: 113827503
TUT: 107362919
DPTE: 113794702
CSCU: 111640261
PTEP: 107449997
CEL: CELE_K09B11.1(pik-1)
CBR: CBG01770(Cbr-pik-1)
BMY: Bm1_38375
PCAN: 112571551
AQU: 100640145
GRA: 105790163
VRA: 106752406
VUN: 114191517
CAM: 101497760
LJA: Lj2g3v1560690.1(Lj2g3v1560690.1) Lj2g3v2736550.1(Lj2g3v2736550.1) Lj4g3v2120390.1(Lj4g3v2120390.1)
LANG: 109363033
MCHA: 111018512
VVI: 100258860
SOT: 102596037
DOSA: Os02t0215900-01(Os02g0215900) Os08t0331900-01(Os08g0331900)
ATS: 109733592(LOC109733592) 109735060(LOC109735060) 109735370(LOC109735370) 109736317(LOC109736317) 109738587(LOC109738587) 109739951(LOC109739951) 109753193(LOC109753193) 109754271(LOC109754271) 109762466(LOC109762466) 109764048(LOC109764048) 109764514(LOC109764514) 109774461(LOC109774461) 109774463(LOC109774463) 109775363(LOC109775363) 109775375(LOC109775375) 109775629(LOC109775629) 109784012(LOC109784012)
PDA: 103724158
SMIN: v1.2.006703.t1(symbB.v1.2.006703.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jensen LE, Whitehead AS
  Title
IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability.
  Journal
J Biol Chem 276:29037-44 (2001)
DOI:10.1074/jbc.M103815200
  Sequence
[hsa:3654]

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