KEGG   ORTHOLOGY: K04735
Entry
K04735                      KO                                     

Symbol
RELA
Name
transcription factor p65
Pathway
map01523  Antifolate resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04064  NF-kappa B signaling pathway
map04066  HIF-1 signaling pathway
map04071  Sphingolipid signaling pathway
map04137  Mitophagy - animal
map04151  PI3K-Akt signaling pathway
map04210  Apoptosis
map04211  Longevity regulating pathway
map04218  Cellular senescence
map04380  Osteoclast differentiation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04623  Cytosolic DNA-sensing pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04722  Neurotrophin signaling pathway
map04917  Prolactin signaling pathway
map04920  Adipocytokine signaling pathway
map04926  Relaxin signaling pathway
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04936  Alcoholic liver disease
map05010  Alzheimer disease
map05022  Pathways of neurodegeneration - multiple diseases
map05030  Cocaine addiction
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05133  Pertussis
map05134  Legionellosis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
map05203  Viral carcinogenesis
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05212  Pancreatic cancer
map05215  Prostate cancer
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05321  Inflammatory bowel disease
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04735  RELA; transcription factor p65
   04014 Ras signaling pathway
    K04735  RELA; transcription factor p65
   04064 NF-kappa B signaling pathway
    K04735  RELA; transcription factor p65
   04668 TNF signaling pathway
    K04735  RELA; transcription factor p65
   04066 HIF-1 signaling pathway
    K04735  RELA; transcription factor p65
   04071 Sphingolipid signaling pathway
    K04735  RELA; transcription factor p65
   04024 cAMP signaling pathway
    K04735  RELA; transcription factor p65
   04151 PI3K-Akt signaling pathway
    K04735  RELA; transcription factor p65
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K04735  RELA; transcription factor p65
  09143 Cell growth and death
   04210 Apoptosis
    K04735  RELA; transcription factor p65
   04218 Cellular senescence
    K04735  RELA; transcription factor p65
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K04735  RELA; transcription factor p65
   04620 Toll-like receptor signaling pathway
    K04735  RELA; transcription factor p65
   04621 NOD-like receptor signaling pathway
    K04735  RELA; transcription factor p65
   04622 RIG-I-like receptor signaling pathway
    K04735  RELA; transcription factor p65
   04623 Cytosolic DNA-sensing pathway
    K04735  RELA; transcription factor p65
   04625 C-type lectin receptor signaling pathway
    K04735  RELA; transcription factor p65
   04660 T cell receptor signaling pathway
    K04735  RELA; transcription factor p65
   04658 Th1 and Th2 cell differentiation
    K04735  RELA; transcription factor p65
   04659 Th17 cell differentiation
    K04735  RELA; transcription factor p65
   04657 IL-17 signaling pathway
    K04735  RELA; transcription factor p65
   04662 B cell receptor signaling pathway
    K04735  RELA; transcription factor p65
   04062 Chemokine signaling pathway
    K04735  RELA; transcription factor p65
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K04735  RELA; transcription factor p65
   04917 Prolactin signaling pathway
    K04735  RELA; transcription factor p65
   04926 Relaxin signaling pathway
    K04735  RELA; transcription factor p65
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04735  RELA; transcription factor p65
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04735  RELA; transcription factor p65
  09149 Aging
   04211 Longevity regulating pathway
    K04735  RELA; transcription factor p65
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04735  RELA; transcription factor p65
   05202 Transcriptional misregulation in cancer
    K04735  RELA; transcription factor p65
   05207 Chemical carcinogenesis - receptor activation
    K04735  RELA; transcription factor p65
   05208 Chemical carcinogenesis - reactive oxygen species
    K04735  RELA; transcription factor p65
   05203 Viral carcinogenesis
    K04735  RELA; transcription factor p65
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04735  RELA; transcription factor p65
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K04735  RELA; transcription factor p65
   05221 Acute myeloid leukemia
    K04735  RELA; transcription factor p65
   05220 Chronic myeloid leukemia
    K04735  RELA; transcription factor p65
   05215 Prostate cancer
    K04735  RELA; transcription factor p65
   05222 Small cell lung cancer
    K04735  RELA; transcription factor p65
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04735  RELA; transcription factor p65
   05170 Human immunodeficiency virus 1 infection
    K04735  RELA; transcription factor p65
   05161 Hepatitis B
    K04735  RELA; transcription factor p65
   05160 Hepatitis C
    K04735  RELA; transcription factor p65
   05171 Coronavirus disease - COVID-19
    K04735  RELA; transcription factor p65
   05164 Influenza A
    K04735  RELA; transcription factor p65
   05162 Measles
    K04735  RELA; transcription factor p65
   05168 Herpes simplex virus 1 infection
    K04735  RELA; transcription factor p65
   05163 Human cytomegalovirus infection
    K04735  RELA; transcription factor p65
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04735  RELA; transcription factor p65
   05169 Epstein-Barr virus infection
    K04735  RELA; transcription factor p65
   05165 Human papillomavirus infection
    K04735  RELA; transcription factor p65
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04735  RELA; transcription factor p65
   05130 Pathogenic Escherichia coli infection
    K04735  RELA; transcription factor p65
   05132 Salmonella infection
    K04735  RELA; transcription factor p65
   05131 Shigellosis
    K04735  RELA; transcription factor p65
   05135 Yersinia infection
    K04735  RELA; transcription factor p65
   05133 Pertussis
    K04735  RELA; transcription factor p65
   05134 Legionellosis
    K04735  RELA; transcription factor p65
   05152 Tuberculosis
    K04735  RELA; transcription factor p65
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K04735  RELA; transcription factor p65
   05145 Toxoplasmosis
    K04735  RELA; transcription factor p65
   05140 Leishmaniasis
    K04735  RELA; transcription factor p65
   05142 Chagas disease
    K04735  RELA; transcription factor p65
  09163 Immune disease
   05321 Inflammatory bowel disease
    K04735  RELA; transcription factor p65
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04735  RELA; transcription factor p65
   05022 Pathways of neurodegeneration - multiple diseases
    K04735  RELA; transcription factor p65
  09165 Substance dependence
   05030 Cocaine addiction
    K04735  RELA; transcription factor p65
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04735  RELA; transcription factor p65
   05418 Fluid shear stress and atherosclerosis
    K04735  RELA; transcription factor p65
   05415 Diabetic cardiomyopathy
    K04735  RELA; transcription factor p65
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04735  RELA; transcription factor p65
   04932 Non-alcoholic fatty liver disease
    K04735  RELA; transcription factor p65
   04931 Insulin resistance
    K04735  RELA; transcription factor p65
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04735  RELA; transcription factor p65
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    K04735  RELA; transcription factor p65
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04735  RELA; transcription factor p65
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    K04735  RELA; transcription factor p65
Genes
HSA: 5970(RELA)
PTR: 466665(RELA)
PPS: 100988429(RELA)
GGO: 101150285(RELA)
PON: 100456049(RELA)
NLE: 100588439(RELA)
MCC: 715919(RELA)
MCF: 101867324(RELA)
CSAB: 103227364(RELA)
CATY: 105577432(RELA)
PANU: 101017078(RELA)
RRO: 104664815(RELA)
RBB: 108543519(RELA)
TFN: 117081405(RELA)
PTEH: 111522422(RELA)
CJC: 100388493(RELA)
SBQ: 101035406(RELA)
MMUR: 105878531(RELA)
MMU: 19697(Rela)
MCAL: 110285703(Rela)
MPAH: 110317041(Rela)
RNO: 309165(Rela)
MCOC: 116103403(Rela)
MUN: 110549347(Rela)
CGE: 100763542(Rela)
PLEU: 114682099(Rela)
NGI: 103724994(Rela)
HGL: 101716738(Rela)
CPOC: 100724366(Rela)
CCAN: 109687142(Rela)
OPI: 101530066(RELA)
TUP: 102490451(RELA)
CFA: 483729(RELA)
VVP: 112924254(RELA)
VLG: 121471268(RELA)
AML: 100480158(RELA)
UMR: 103679584(RELA)
UAH: 113244102(RELA)
ORO: 101381225(RELA)
ELK: 111149956
MPUF: 101680239(RELA)
EJU: 114220346(RELA)
MLX: 118016059(RELA)
FCA: 101096604(RELA)
PYU: 121023959(RELA)
PBG: 122484468(RELA)
PTG: 102951132(RELA)
PPAD: 109246747(RELA)
AJU: 106971136(RELA)
HHV: 120240185(RELA)
BTA: 508233(RELA)
BOM: 102268417(RELA)
BIU: 109554392(RELA)
BBUB: 102397938(RELA)
CHX: 102174096(RELA)
OAS: 101102191(RELA)
ODA: 120874649(RELA)
CCAD: 122430633(RELA)
SSC: 100135665(RELA)
CFR: 102506204(RELA)
CBAI: 105070689(RELA)
CDK: 105102595(RELA)
BACU: 103019614(RELA)
LVE: 103087304(RELA)
OOR: 101270342(RELA)
DLE: 111183745(RELA)
PCAD: 102974198(RELA)
PSIU: 116758150(RELA)
ECB: 100057483(RELA)
EPZ: 103543692(RELA)
EAI: 106833569(RELA)
MYB: 102263790(RELA)
MYD: 102770704(RELA)
MMYO: 118665292(RELA)
MNA: 107533544(RELA)
PKL: 118706879(RELA)
HAI: 109384322(RELA)
DRO: 112317202(RELA)
SHON: 118991736(RELA)
AJM: 119050282(RELA)
PDIC: 114499888(RELA)
MMF: 118628367(RELA)
RFQ: 117030742(RELA)
PALE: 102878395(RELA)
PGIG: 120584840(RELA)
RAY: 107497522(RELA)
MJV: 108397005(RELA)
TOD: 119248814(RELA)
LAV: 100654730(RELA)
TMU: 101361706
MDO: 100030053(RELA)
GAS: 123251290(RELA)
SHR: 100932473(RELA)
PCW: 110195563(RELA)
OAA: 100074633(RELA)
GGA: 396027(RELA)
CJO: 107307430
TGU: 115492066(RELA)
LSR: 110478845(RELA)
PMOA: 120507316(RELA)
OTC: 121340600(RELA)
PHI: 102105891(RELA)
CCW: 120412318
ASN: 102377458(RELA)
AMJ: 102573364(RELA)
PSS: 102457804(RELA)
CMY: 102947354(RELA)
CPIC: 101933001(RELA)
TST: 117880425(RELA)
CABI: 116838783(RELA)
ACS: 100556163(rela)
PVT: 110069799(RELA)
SUND: 121915610(RELA)
PBI: 103050942(RELA)
PMUR: 107297118(RELA)
TSR: 106556843(RELA)
PGUT: 117669743(RELA)
VKO: 123032554(RELA)
PMUA: 114587106(RELA)
ZVI: 118075687(RELA)
GJA: 107115220(RELA)
XLA: 108715128(rela.S) 394353(rela.L)
XTR: 407869(rela)
NPR: 108784114(RELA)
DRE: 415099(rela)
SGH: 107573921 107574010(rela)
IPU: 108260779
PHYP: 113545743
AMEX: 103032041
EEE: 113584194
TRU: 101073743
LCO: 109141199
NCC: 104965780(rela)
CGOB: 115023463
ELY: 117246128(rela)
PLEP: 121961933(rela)
SLUC: 116036053(rela)
ECRA: 117934772(rela)
PFLV: 114545913
GAT: 120821327(rela)
PPUG: 119222459(rela)
MSAM: 119911844(rela)
CUD: 121504461(rela)
MZE: 101487989(rela)
ONL: 100707676(rela)
OAU: 116335817(rela)
OLA: 101158728
OML: 112155860(rela)
XMA: 102219636
XCO: 114157395
XHE: 116732698
PRET: 103480184
GAF: 122820524(rela)
CVG: 107082800(rela)
CTUL: 119772111(rela)
NFU: 107376749
KMR: 108239405(rela)
ALIM: 106523725
AOCE: 111582710
CSEM: 103385629
POV: 109637639
SSEN: 122765911(rela)
HHIP: 117751799(rela)
LCF: 108882042
SDU: 111226894(rela)
SLAL: 111670446(rela)
XGL: 120797026(rela)
HCQ: 109508419
BPEC: 110168801
MALB: 109969432(rela)
ELS: 105020694
SFM: 108934391
AANG: 118223522(rela) 118236176
PSPA: 121310074(rela)
BFO: 118423605
FAS: 105269252
DAM: 107040546
AGB: 108916217
CRG: 105319044
OSN: 115217075
 » show all
Reference
PMID:2006423
  Authors
Ruben SM, Dillon PJ, Schreck R, Henkel T, Chen CH, Maher M, Baeuerle PA, Rosen CA
  Title
Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.
  Journal
Science 251:1490-3 (1991)
DOI:10.1126/science.2006423
  Sequence
[hsa:5970]

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