KEGG   ORTHOLOGY: K04849Help
Entry
K04849                      KO                                     

Name
CACNA1B, CAV2.2
Definition
voltage-dependent calcium channel N type alpha-1B
Pathway
ko04010  MAPK signaling pathway
ko04020  Calcium signaling pathway
ko04721  Synaptic vesicle cycle
ko04723  Retrograde endocannabinoid signaling
ko04725  Cholinergic synapse
ko04726  Serotonergic synapse
ko04727  GABAergic synapse
ko04728  Dopaminergic synapse
ko04930  Type II diabetes mellitus
ko05032  Morphine addiction
ko05033  Nicotine addiction
Disease
H00831  Primary dystonia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04020 Calcium signaling pathway
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04725 Cholinergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04728 Dopaminergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04726 Serotonergic synapse
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04723 Retrograde endocannabinoid signaling
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   04721 Synaptic vesicle cycle
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
   05033 Nicotine addiction
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated
   K04849  CACNA1B, CAV2.2; voltage-dependent calcium channel N type alpha-1B
BRITE hierarchy
Other DBs
GO: 0005245
TC: 1.A.1.11.9
Genes
HSA: 774(CACNA1B)
PTR: 464893(CACNA1B)
PPS: 100979369(CACNA1B)
GGO: 101123776(CACNA1B)
PON: 100450868(CACNA1B)
NLE: 100584807(CACNA1B)
MCC: 721452(CACNA1B)
MCF: 101925455
CSAB: 103239541(CACNA1B)
RRO: 104669605(CACNA1B)
RBB: 108542921(CACNA1B)
CJC: 100390442(CACNA1B)
SBQ: 101049976(CACNA1B)
MMU: 12287(Cacna1b)
RNO: 257648(Cacna1b)
NGI: 103732608(Cacna1b)
HGL: 101697609(Cacna1b)
OCU: 100008979(CACNA1B)
TUP: 102498317(CACNA1B)
CFA: 480660(CACNA1B)
AML: 100466608(CACNA1B)
UMR: 103675324(CACNA1B)
FCA: 101087362(CACNA1B)
PTG: 102954775(CACNA1B)
BTA: 282410(CACNA1B)
BOM: 102266839(CACNA1B)
BIU: 109565692(CACNA1B)
PHD: 102330644(CACNA1B)
CHX: 102189138(CACNA1B)
OAS: 101122774
SSC: 102164336(CACNA1B)
CFR: 102521766(CACNA1B)
CDK: 105102103(CACNA1B)
BACU: 103004988(CACNA1B)
LVE: 103073411(CACNA1B)
OOR: 101272416(CACNA1B)
ECB: 100058760(CACNA1B)
EPZ: 103554173(CACNA1B)
EAI: 106822757(CACNA1B)
MYB: 102245786(CACNA1B)
MYD: 102756826(CACNA1B)
HAI: 109382541(CACNA1B)
RSS: 109437268(CACNA1B)
PALE: 102877847(CACNA1B)
LAV: 100660444(CACNA1B)
TMU: 101351661
MDO: 100023896(CACNA1B)
SHR: 100933192(CACNA1B)
OAA: 100681261(CACNA1B)
GGA: 374169(CACNA1B)
MGP: 100539318(CACNA1B)
CJO: 107321666(CACNA1B)
APLA: 101794161(CACNA1B)
ACYG: 106037093(CACNA1B)
TGU: 100230125(CACNA1B)
GFR: 102043304(CACNA1B)
FAB: 101812454(CACNA1B)
PHI: 102107124(CACNA1B)
PMAJ: 107211935(CACNA1B)
CCW: 104688232(CACNA1B)
FPG: 101922058(CACNA1B)
FCH: 102058219(CACNA1B)
CLV: 102086328(CACNA1B)
EGZ: 104124015(CACNA1B)
AAM: 106497478(CACNA1B)
ASN: 102374664(CACNA1B)
AMJ: 102564626(CACNA1B)
PSS: 102452356(CACNA1B)
CMY: 102935334(CACNA1B)
CPIC: 101941901(CACNA1B)
ACS: 100565533(cacna1b)
PVT: 110089800(CACNA1B)
PBI: 103051885
GJA: 107118784(CACNA1B)
XLA: 100462926(cacna1b.S) 108699890
XTR: 100489231
NPR: 108794388(CACNA1B)
DRE: 555941(cacna1ba) 562796(cacna1bb)
TRU: 101072690(cacna1b)
LCF: 108878412(cacna1b) 108889014
HCQ: 109527074
LCM: 102345610(CACNA1B)
CMK: 103180424(cacna1b)
CIN: 100184382
TSP: Tsp_10911
MYI: 110467402
OBI: 106879088
LAK: 106170041
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Keum D, Baek C, Kim DI, Kweon HJ, Suh BC
  Title
Voltage-dependent regulation of CaV2.2 channels by Gq-coupled receptor is facilitated by membrane-localized beta subunit.
  Journal
J Gen Physiol 144:297-309 (2014)
DOI:10.1085/jgp.201411245
  Sequence
[hsa:774]

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