KEGG   ORTHOLOGY: K04858Help
Entry
K04858                      KO                                     

Name
CACNA2D1
Definition
voltage-dependent calcium channel alpha-2/delta-1
Pathway
ko04010  MAPK signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04921  Oxytocin signaling pathway
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
   04261 Adrenergic signaling in cardiomyocytes
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
 09160 Human Diseases
  09166 Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
   05414 Dilated cardiomyopathy (DCM)
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04858  CACNA2D1; voltage-dependent calcium channel alpha-2/delta-1
BRITE hierarchy
Other DBs
GO: 0005245
TC: 8.A.18.1
Genes
HSA: 781(CACNA2D1)
PTR: 463504(CACNA2D1)
PPS: 100982794(CACNA2D1)
GGO: 101128490(CACNA2D1)
PON: 100171724(CACNA2D1)
NLE: 100595072(CACNA2D1)
MCC: 708215(CACNA2D1)
MCF: 102131750(CACNA2D1)
CSAB: 103226639(CACNA2D1)
RRO: 104681577(CACNA2D1)
RBB: 108536908(CACNA2D1)
CJC: 100385605(CACNA2D1)
SBQ: 101053043(CACNA2D1)
MMU: 12293(Cacna2d1)
RNO: 25399(Cacna2d1)
CGE: 100764769(Cacna2d1)
NGI: 103730725(Cacna2d1)
HGL: 101708369(Cacna2d1)
CCAN: 109681780(Cacna2d1)
OCU: 100009105(CACNA2D1)
TUP: 102482417(CACNA2D1)
CFA: 610342(CACNA2D1)
AML: 100463812(CACNA2D1)
UMR: 103658778(CACNA2D1)
ORO: 101373490(CACNA2D1)
FCA: 101099450(CACNA2D1)
PTG: 102951633(CACNA2D1)
AJU: 106975662(CACNA2D1)
BTA: 282608(CACNA2D1)
BOM: 102268507(CACNA2D1)
BIU: 109557331(CACNA2D1)
PHD: 102316329(CACNA2D1)
CHX: 102183035(CACNA2D1)
OAS: 101123550(CACNA2D1)
SSC: 397377(CACNA2D1)
CFR: 102520107 106729917(CACNA2D1)
CDK: 105087345(CACNA2D1)
BACU: 103020121(CACNA2D1)
LVE: 103082365(CACNA2D1)
OOR: 101273913(CACNA2D1)
ECB: 100057533(CACNA2D1)
EPZ: 103560846(CACNA2D1)
EAI: 106840179(CACNA2D1)
MYB: 102238945(CACNA2D1)
MYD: 102774068(CACNA2D1)
HAI: 109392343(CACNA2D1)
RSS: 109455381(CACNA2D1)
PALE: 102888058(CACNA2D1)
LAV: 100676022(CACNA2D1)
TMU: 101345222
MDO: 100012746(CACNA2D1)
SHR: 100915174(CACNA2D1)
OAA: 100074856(CACNA2D1)
GGA: 768444(CACNA2D1)
CJO: 107321641(CACNA2D1)
APLA: 101793350(CACNA2D1)
ACYG: 106035544(CACNA2D1)
TGU: 100227443(CACNA2D1)
SCAN: 103813738(CACNA2D1)
GFR: 102042376(CACNA2D1)
FAB: 101820977(CACNA2D1)
PHI: 102112187(CACNA2D1)
PMAJ: 107204625(CACNA2D1)
CCAE: 111923300(CACNA2D1) 111923301
CCW: 104686893(CACNA2D1)
FPG: 101917007(CACNA2D1)
FCH: 102059307(CACNA2D1)
CLV: 102088083(CACNA2D1)
EGZ: 104132378(CACNA2D1)
NNI: 104010753(CACNA2D1)
ACUN: 113487405(CACNA2D1)
AAM: 106485587(CACNA2D1)
ASN: 102386090(CACNA2D1)
AMJ: 102565821(CACNA2D1)
PSS: 102450076(CACNA2D1)
CMY: 102938285
CPIC: 101946496(CACNA2D1)
ACS: 100566428(cacna2d1)
PVT: 110077205(CACNA2D1)
PBI: 103064448(CACNA2D1)
GJA: 107110493 107124567(CACNA2D1)
XLA: 108711204(cacna2d1.L) 108713061(cacna2d1.S)
XTR: 100036724(cacna2d1)
NPR: 108792727(CACNA2D1)
DRE: 561434(cacna2d1a)
IPU: 108264659(cacna2d1)
PHYP: 113534270(cacna2d1)
TRU: 101064543(cacna2d1) 101079089
LCO: 104918121(cacna2d1) 104918796
MZE: 101476728(cacna2d1) 101486293
OLA: 101156213
PRET: 103459225 103465999(cacna2d1)
NFU: 107385644 107388870(cacna2d1)
KMR: 108230132(cacna2d1) 108235077
SDU: 111224485 111228383(cacna2d1)
BPEC: 110161913(cacna2d1) 110166803
MALB: 109959825 109967519(cacna2d1)
SALP: 111962521
SFM: 108921141(cacna2d1) 108936376
LCM: 102355436(CACNA2D1)
CMK: 103177010(cacna2d1)
CIN: 100186976
SKO: 102804829
SHX: MS3_09135
PDAM: 113684765
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Hoppa MB, Lana B, Margas W, Dolphin AC, Ryan TA
  Title
alpha2delta expression sets presynaptic calcium channel abundance and release probability.
  Journal
Nature 486:122-5 (2012)
DOI:10.1038/nature11033
  Sequence
[hsa:781]

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