K04860                      KO                                     

voltage-dependent calcium channel alpha-2/delta-3
ko04010  MAPK signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04921  Oxytocin signaling pathway
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
   04261 Adrenergic signaling in cardiomyocytes
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
   05414 Dilated cardiomyopathy (DCM)
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04860  CACNA2D3; voltage-dependent calcium channel alpha-2/delta-3
BRITE hierarchy
Other DBs
GO: 0005245
TC: 8.A.18.3
HSA: 55799(CACNA2D3)
PTR: 460457(CACNA2D3)
PPS: 100972163(CACNA2D3)
GGO: 101147075(CACNA2D3)
PON: 100448999(CACNA2D3)
NLE: 100601674(CACNA2D3)
MCC: 693356(CACNA2D3)
MCF: 102143606(CACNA2D3)
CSAB: 103227772(CACNA2D3)
RRO: 104662214(CACNA2D3)
RBB: 108515798(CACNA2D3)
CJC: 100400467(CACNA2D3)
SBQ: 101040923(CACNA2D3)
MMU: 12294(Cacna2d3)
MCAL: 110309146(Cacna2d3)
MPAH: 110325173(Cacna2d3)
RNO: 306243(Cacna2d3)
MUN: 110546918(Cacna2d3)
CGE: 100753384(Cacna2d3)
NGI: 103749031(Cacna2d3)
HGL: 101712827(Cacna2d3)
OCU: 100351327(CACNA2D3)
TUP: 102489976(CACNA2D3)
CFA: 476585(CACNA2D3)
VVP: 112909997(CACNA2D3)
AML: 100483814(CACNA2D3)
UMR: 103674731(CACNA2D3)
UAH: 113256988(CACNA2D3)
ORO: 101369586(CACNA2D3)
FCA: 101094658(CACNA2D3)
PTG: 102957490(CACNA2D3)
PPAD: 109279120(CACNA2D3)
AJU: 106967034(CACNA2D3)
BTA: 519644(CACNA2D3)
BOM: 102269496(CACNA2D3)
BIU: 109575867
BBUB: 102402860(CACNA2D3)
CHX: 102172849(CACNA2D3)
OAS: 101105365(CACNA2D3)
SSC: 100153986(CACNA2D3)
CFR: 102505114
CDK: 105089780(CACNA2D3)
BACU: 103004210(CACNA2D3)
LVE: 103076318(CACNA2D3)
OOR: 101278227(CACNA2D3)
DLE: 111174274(CACNA2D3)
PCAD: 102981182(CACNA2D3)
ECB: 100059197(CACNA2D3)
EPZ: 103565858(CACNA2D3)
EAI: 106843313 106848683(CACNA2D3)
MYB: 102239827
MYD: 102763556(CACNA2D3)
MNA: 107530629(CACNA2D3)
DRO: 112301237(CACNA2D3)
PALE: 102890987(CACNA2D3)
RAY: 107516533(CACNA2D3)
LAV: 100659138(CACNA2D3)
TMU: 101358626
MDO: 100013859(CACNA2D3)
SHR: 100918190(CACNA2D3)
PCW: 110197042(CACNA2D3)
OAA: 100077460(CACNA2D3)
GGA: 415996(CACNA2D3)
MGP: 100546053(CACNA2D3)
CJO: 107320005(CACNA2D3)
NMEL: 110404674(CACNA2D3)
APLA: 101790806(CACNA2D3)
ACYG: 106040528(CACNA2D3)
TGU: 100222087(CACNA2D3)
LSR: 110471861(CACNA2D3)
SCAN: 103816995(CACNA2D3)
GFR: 102037102(CACNA2D3)
FAB: 101821271(CACNA2D3)
PHI: 102102557(CACNA2D3)
PMAJ: 107210399(CACNA2D3)
CCW: 104683260(CACNA2D3)
ETL: 114057959(CACNA2D3)
FPG: 101916160(CACNA2D3)
FCH: 102054020(CACNA2D3)
CLV: 102089718(CACNA2D3)
EGZ: 104126728(CACNA2D3)
NNI: 104015320(CACNA2D3)
ACUN: 113484883(CACNA2D3)
PADL: 103925487(CACNA2D3)
AAM: 106493862 106495161(CACNA2D3)
ASN: 102373454(CACNA2D3)
AMJ: 102570532(CACNA2D3)
PSS: 102448983(CACNA2D3)
CMY: 102933361(CACNA2D3)
CPIC: 101932053(CACNA2D3)
ACS: 100555458(cacna2d3)
PVT: 110084963(CACNA2D3)
PMUR: 107289410(CACNA2D3)
TSR: 106553921(CACNA2D3)
PMUA: 114591690(CACNA2D3)
GJA: 107109400(CACNA2D3)
XLA: 108704004(cacna2d3.L) 373777(cacna2d3.S)
XTR: 101732520(cacna2d3)
NPR: 108786049(CACNA2D3)
DRE: 100148645(cacna2d3) 100535196(cacna2d3a)
SANH: 107659556(cacna2d3) 107686000 107693597
IPU: 108254724 108265794(cacna2d3)
PHYP: 113533340(cacna2d3) 113539459
AMEX: 103032408(cacna2d3) 103035144
MZE: 101467919(cacna2d3) 101486968
KMR: 108235237(cacna2d3) 108247370
POV: 109635036 109638461(cacna2d3)
HCQ: 109522322 109528651(cacna2d3)
BPEC: 110164934(cacna2d3) 110168660
MALB: 109951927 109971450(cacna2d3)
SFM: 108925576(cacna2d3) 108933830
PKI: 111833382(cacna2d3) 111848761 111852528
LCM: 102354765(CACNA2D3)
CMK: 103176769(cacna2d3)
RTP: 109932632(cacna2d3)
SPU: 100890679
APLC: 110982123
DME: Dmel_CG12295(stj)
DER: 6549504
DSI: Dsimw501_GD10984(Dsim_GD10984)
DSR: 110189254
DPE: 6592379
DMN: 108160677
DWI: 6646109
DNV: 108654409
DHE: 111595414
MDE: 101895300
LCQ: 111675131
AAG: 5567755
AME: 408841
BIM: 100745928
BTER: 100651196
CCAL: 108631002
OBB: 114872872
SOC: 105200388
MPHA: 105834874
AEC: 105143904
PBAR: 105431109
VEM: 105566749
HST: 105181352
DQU: 106744438
CFO: 105253687
LHU: 105674568
PGC: 109859364
OBO: 105277632
NVI: 100122943
CSOL: 105363041
MDL: 103573139
TCA: 662338
PXY: 105397600
API: 100161432
DNX: 107167741
AGS: 114132303
RMD: 113556069
BTAB: 109040642
CLEC: 106668919
PVM: 113824452
PTEP: 107437533
PCAN: 112572968
MYI: 110460993
EGL: EGR_00561
DGT: 114524865
 » show all
Pirone A, Kurt S, Zuccotti A, Ruttiger L, Pilz P, Brown DH, Franz C, Schweizer M, Rust MB, Rubsamen R, Friauf E, Knipper M, Engel J
alpha2delta3 is essential for normal structure and function of auditory nerve synapses and is a novel candidate for auditory processing disorders.
J Neurosci 34:434-45 (2014)

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