KEGG   ORTHOLOGY: K04865Help
Entry
K04865                      KO                                     

Name
CACNB4
Definition
voltage-dependent calcium channel beta-4
Pathway
ko04010  MAPK signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04921  Oxytocin signaling pathway
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00749  Episodic ataxias
H00808  Idiopathic generalized epilepsies (IGEs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K04865  CACNB4; voltage-dependent calcium channel beta-4
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    K04865  CACNB4; voltage-dependent calcium channel beta-4
  Circulatory system
   04260 Cardiac muscle contraction
    K04865  CACNB4; voltage-dependent calcium channel beta-4
   04261 Adrenergic signaling in cardiomyocytes
    K04865  CACNB4; voltage-dependent calcium channel beta-4
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K04865  CACNB4; voltage-dependent calcium channel beta-4
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04865  CACNB4; voltage-dependent calcium channel beta-4
   05414 Dilated cardiomyopathy (DCM)
    K04865  CACNB4; voltage-dependent calcium channel beta-4
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated
   K04865  CACNB4; voltage-dependent calcium channel beta-4
BRITE hierarchy
Other DBs
GO: 0005245
TC: 8.A.22.1.4
Genes
HSA: 785(CACNB4)
PTR: 459660(CACNB4)
PPS: 100976785(CACNB4)
GGO: 101137663(CACNB4)
PON: 100444432(CACNB4)
NLE: 100597041(CACNB4)
MCC: 695172(CACNB4)
MCF: 102116137(CACNB4)
CSAB: 103217090(CACNB4)
RRO: 104669805(CACNB4)
RBB: 108525018(CACNB4)
CJC: 100393056(CACNB4)
SBQ: 101031728(CACNB4)
MMU: 12298(Cacnb4)
RNO: 58942(Cacnb4)
CGE: 100765888(Cacnb4)
NGI: 103738122(Cacnb4)
HGL: 101723713(Cacnb4)
CCAN: 109695158(Cacnb4)
OCU: 100344224(CACNB4)
TUP: 102474154(CACNB4)
CFA: 609361(CACNB4)
AML: 100464104(CACNB4)
UMR: 103659848(CACNB4)
ORO: 101374377(CACNB4)
FCA: 101101576(CACNB4)
PTG: 102953668(CACNB4)
AJU: 106976065(CACNB4)
BTA: 282161(CACNB4)
BOM: 102265990(CACNB4)
BIU: 109567608(CACNB4)
PHD: 102324508(CACNB4)
CHX: 102179332(CACNB4)
OAS: 101117907(CACNB4)
SSC: 396585(CACNB4)
CFR: 102518736(CACNB4)
CDK: 105093727(CACNB4)
BACU: 103013367(CACNB4)
LVE: 103089902(CACNB4)
OOR: 101269896(CACNB4)
ECB: 100057916(CACNB4)
EPZ: 103558127(CACNB4)
EAI: 106824678(CACNB4)
MYB: 102261332(CACNB4)
MYD: 102752339(CACNB4)
HAI: 109384861(CACNB4)
RSS: 109450293(CACNB4)
PALE: 102896224(CACNB4)
LAV: 100656938(CACNB4)
TMU: 101351408
MDO: 100019993(CACNB4)
SHR: 100924116(CACNB4)
OAA: 100080287(CACNB4)
GGA: 374259(CACNB4)
MGP: 100544561(CACNB4)
CJO: 107316971(CACNB4)
APLA: 101798353(CACNB4)
ACYG: 106046874(CACNB4)
TGU: 100225217(CACNB4)
GFR: 102035820(CACNB4)
FAB: 101815605(CACNB4)
PHI: 102111016(CACNB4)
PMAJ: 107207455(CACNB4)
CCW: 104694105(CACNB4)
FPG: 101918928(CACNB4)
FCH: 102054191(CACNB4)
CLV: 102085477(CACNB4)
EGZ: 104130401(CACNB4)
AAM: 106482299(CACNB4)
ASN: 102368360(CACNB4)
AMJ: 106736635(CACNB4)
PSS: 102450169(CACNB4)
CMY: 102932640(CACNB4)
CPIC: 101941206(CACNB4)
ACS: 100337606(cacnb4)
PVT: 110080837(CACNB4)
PBI: 103053209(CACNB4)
GJA: 107125599(CACNB4)
XTR: 100216182(cacnb4)
NPR: 108784717(CACNB4)
DRE: 562422(cacnb4a) 678560(cacnb4b)
IPU: 108266240 108272385(CACNB4)
AMEX: 103031296(cacnb4) 103041078
TRU: 101065065(cacnb4.1) 101070730(cacnb4)
NCC: 104953958 104962611(cacnb4)
MZE: 101466725 101481806(cacnb4)
OLA: 100192310(cacnb4.1)
XMA: 102233017
PRET: 103475101 103478450(cacnb4)
NFU: 107380913 107389651(cacnb4)
LCF: 108892915 108897092(cacnb4)
BPEC: 110156629(cacnb4) 110163257
ELS: 105016118(cacnb4) 105023164
SFM: 108930040(cacnb4) 108936607
LCM: 102367248(CACNB4)
CMK: 103180441(cacnb4)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tadmouri A, Kiyonaka S, Barbado M, Rousset M, Fablet K, Sawamura S, Bahembera E, Pernet-Gallay K, Arnoult C, Miki T, Sadoul K, Gory-Faure S, Lambrecht C, Lesage F, Akiyama S, Khochbin S, Baulande S, Janssens V, Andrieux A, Dolmetsch R, Ronjat M, Mori Y, De Waard M
  Title
Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy.
  Journal
EMBO J 31:3730-44 (2012)
DOI:10.1038/emboj.2012.226
  Sequence
[hsa:785]

DBGET integrated database retrieval system