KEGG   ORTHOLOGY: K04865Help
Entry
K04865                      KO                                     

Name
CACNB4
Definition
voltage-dependent calcium channel beta-4
Pathway
ko04010  MAPK signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04921  Oxytocin signaling pathway
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00749  Episodic ataxias
H00808  Idiopathic generalized epilepsies
H02217  Juvenile myoclonic epilepsy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04865  CACNB4; voltage-dependent calcium channel beta-4
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K04865  CACNB4; voltage-dependent calcium channel beta-4
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K04865  CACNB4; voltage-dependent calcium channel beta-4
   04261 Adrenergic signaling in cardiomyocytes
    K04865  CACNB4; voltage-dependent calcium channel beta-4
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy (HCM)
    K04865  CACNB4; voltage-dependent calcium channel beta-4
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04865  CACNB4; voltage-dependent calcium channel beta-4
   05414 Dilated cardiomyopathy (DCM)
    K04865  CACNB4; voltage-dependent calcium channel beta-4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04865  CACNB4; voltage-dependent calcium channel beta-4
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   K04865  CACNB4; voltage-dependent calcium channel beta-4
BRITE hierarchy
Other DBs
GO: 0005245
TC: 8.A.22.1.4
Genes
HSA: 785(CACNB4)
PTR: 459660(CACNB4)
PPS: 100976785(CACNB4)
GGO: 101137663(CACNB4)
PON: 100444432(CACNB4)
NLE: 100597041(CACNB4)
MCC: 695172(CACNB4)
MCF: 102116137(CACNB4)
CSAB: 103217090(CACNB4)
RRO: 104669805(CACNB4)
RBB: 108525018(CACNB4)
CJC: 100393056(CACNB4)
SBQ: 101031728(CACNB4)
MMU: 12298(Cacnb4)
MCAL: 110308006(Cacnb4)
MPAH: 110317586(Cacnb4)
RNO: 58942(Cacnb4)
MUN: 110563773(Cacnb4)
CGE: 100765888(Cacnb4)
NGI: 103738122(Cacnb4)
HGL: 101723713(Cacnb4)
CCAN: 109695158(Cacnb4)
OCU: 100344224(CACNB4)
TUP: 102474154(CACNB4)
CFA: 609361(CACNB4)
VVP: 112926879(CACNB4)
AML: 100464104(CACNB4)
UMR: 103659848(CACNB4)
UAH: 113250882(CACNB4)
ORO: 101374377(CACNB4)
FCA: 101101576(CACNB4)
PTG: 102953668(CACNB4)
PPAD: 109271149(CACNB4)
AJU: 106976065(CACNB4)
BTA: 282161(CACNB4)
BOM: 102265990(CACNB4)
BIU: 109567608(CACNB4)
BBUB: 102409578(CACNB4)
CHX: 102179332(CACNB4)
OAS: 101117907(CACNB4)
SSC: 396585(CACNB4)
CFR: 102518736(CACNB4)
CDK: 105093727(CACNB4)
BACU: 103013367(CACNB4)
LVE: 103089902(CACNB4)
OOR: 101269896(CACNB4)
DLE: 111172760(CACNB4)
PCAD: 102977440(CACNB4)
ECB: 100057916(CACNB4)
EPZ: 103558127(CACNB4)
EAI: 106824678(CACNB4)
MYB: 102261332(CACNB4)
MYD: 102752339(CACNB4)
MNA: 107531651(CACNB4)
HAI: 109384861(CACNB4)
DRO: 112312991(CACNB4)
PALE: 102896224(CACNB4)
RAY: 107513916(CACNB4)
MJV: 108406382(CACNB4)
LAV: 100656938(CACNB4)
TMU: 101351408
MDO: 100019993(CACNB4)
SHR: 100924116(CACNB4)
PCW: 110196898(CACNB4)
OAA: 100080287(CACNB4)
GGA: 374259(CACNB4)
MGP: 100544561(CACNB4)
CJO: 107316971(CACNB4)
NMEL: 110399249(CACNB4)
APLA: 101798353(CACNB4)
ACYG: 106046874(CACNB4)
TGU: 100225217(CACNB4)
LSR: 110473132(CACNB4)
SCAN: 103814617(CACNB4)
GFR: 102035820(CACNB4)
FAB: 101815605(CACNB4)
PHI: 102111016(CACNB4)
PMAJ: 107207455(CACNB4)
CCAE: 111932372(CACNB4)
CCW: 104694105(CACNB4)
ETL: 114067462(CACNB4) 114071778
FPG: 101918928(CACNB4)
FCH: 102054191(CACNB4)
CLV: 102085477(CACNB4)
EGZ: 104130401(CACNB4)
NNI: 104012362(CACNB4)
ACUN: 113481993(CACNB4)
PADL: 103912670(CACNB4)
AAM: 106482299(CACNB4)
ASN: 102368360(CACNB4)
AMJ: 106736635(CACNB4)
PSS: 102450169(CACNB4)
CMY: 102932640(CACNB4)
CPIC: 101941206(CACNB4)
ACS: 100337606(cacnb4)
PVT: 110080837(CACNB4)
PBI: 103053209(CACNB4)
PMUR: 107286075
TSR: 106550522(CACNB4)
PMUA: 114605085(CACNB4)
GJA: 107125599(CACNB4)
XTR: 100216182(cacnb4)
NPR: 108784717(CACNB4)
DRE: 562422(cacnb4a) 678560(cacnb4b)
IPU: 108266240 108272385(CACNB4)
AMEX: 103031296(cacnb4) 103041078
TRU: 101065065(cacnb4.1) 101070730(cacnb4)
LCO: 104918232(cacnb4) 104931468
NCC: 104953958 104962611(cacnb4)
MZE: 101466725 101481806(cacnb4)
ONL: 100697371 100697725(cacnb4)
OLA: 100192310(cacnb4.1)
XMA: 102233017
PRET: 103475101 103478450(cacnb4)
CVG: 107092231 107098701(cacnb4)
NFU: 107380913 107389651(cacnb4)
KMR: 108238841(cacnb4) 108244163
AOCE: 111564146(cacnb4) 111586012
POV: 109638020(cacnb4) 109640071
LCF: 108892915 108897092(cacnb4)
SDU: 111218646(cacnb4) 111239914
BPEC: 110156629(cacnb4) 110163257
MALB: 109960559 109974011(cacnb4)
ELS: 105016118(cacnb4) 105023164
SFM: 108930040(cacnb4) 108936607
PKI: 111851740(cacnb4)
LCM: 102367248(CACNB4)
CMK: 103180441(cacnb4)
RTP: 109915118(cacnb4)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tadmouri A, Kiyonaka S, Barbado M, Rousset M, Fablet K, Sawamura S, Bahembera E, Pernet-Gallay K, Arnoult C, Miki T, Sadoul K, Gory-Faure S, Lambrecht C, Lesage F, Akiyama S, Khochbin S, Baulande S, Janssens V, Andrieux A, Dolmetsch R, Ronjat M, Mori Y, De Waard M
  Title
Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy.
  Journal
EMBO J 31:3730-44 (2012)
DOI:10.1038/emboj.2012.226
  Sequence
[hsa:785]

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