KEGG   ORTHOLOGY: K04962Help
Entry
K04962                      KO                                     

Name
RYR2
Definition
ryanodine receptor 2
Pathway
ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04371  Apelin signaling pathway
ko04713  Circadian entrainment
ko04911  Insulin secretion
ko04921  Oxytocin signaling pathway
ko04972  Pancreatic secretion
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00293  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
H01019  Catecholaminergic polymorphic ventricular tachycardia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K04962  RYR2; ryanodine receptor 2
   04020 Calcium signaling pathway
    K04962  RYR2; ryanodine receptor 2
   04024 cAMP signaling pathway
    K04962  RYR2; ryanodine receptor 2
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04962  RYR2; ryanodine receptor 2
   04921 Oxytocin signaling pathway
    K04962  RYR2; ryanodine receptor 2
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K04962  RYR2; ryanodine receptor 2
   04261 Adrenergic signaling in cardiomyocytes
    K04962  RYR2; ryanodine receptor 2
  09154 Digestive system
   04972 Pancreatic secretion
    K04962  RYR2; ryanodine receptor 2
  09159 Environmental adaptation
   04713 Circadian entrainment
    K04962  RYR2; ryanodine receptor 2
 09160 Human Diseases
  09165 Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K04962  RYR2; ryanodine receptor 2
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K04962  RYR2; ryanodine receptor 2
   05414 Dilated cardiomyopathy (DCM)
    K04962  RYR2; ryanodine receptor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04962  RYR2; ryanodine receptor 2
Ion channels [BR:ko04040]
 Voltage-gated cation channels
  Ryanodine receptor
   K04962  RYR2; ryanodine receptor 2
BRITE hierarchy
Other DBs
GO: 0005219
TC: 1.A.3.1
Genes
HSA: 6262(RYR2)
PTR: 457846(RYR2)
PPS: 100974705(RYR2)
GGO: 101152456(RYR2)
PON: 100173051(RYR2)
NLE: 100598810(RYR2)
MCC: 717179(RYR2)
MCF: 102132307(RYR2)
CSAB: 103230821(RYR2)
RRO: 104679189(RYR2)
RBB: 108522194(RYR2)
CJC: 100406916(RYR2)
SBQ: 101044099(RYR2)
MMU: 20191(Ryr2)
RNO: 689560(Ryr2)
CGE: 100774683(Ryr2)
NGI: 103743548
HGL: 101703865(Ryr2)
CCAN: 109682314(Ryr2)
OCU: 100009536(RYR2)
TUP: 102473653(RYR2)
CFA: 403615(RYR2)
AML: 100476576(RYR2)
UMR: 103662005(RYR2)
ORO: 101368222 101372904(RYR2)
FCA: 101084482(RYR2)
PTG: 102963018(RYR2)
AJU: 106987226(RYR2)
BTA: 537376(RYR2)
BOM: 102280999(RYR2)
BIU: 109553606(RYR2)
PHD: 102343273
CHX: 102180565(RYR2)
OAS: 101118500(RYR2)
SSC: 396856(RYR2)
CFR: 102523222
BACU: 103000050(RYR2)
LVE: 103085414(RYR2)
OOR: 101289369(RYR2)
ECB: 100057437(RYR2)
EPZ: 103554178(RYR2)
EAI: 106834687(RYR2)
MYB: 102263572(RYR2)
MYD: 102765493(RYR2)
RSS: 109455319(RYR2)
PALE: 102877858(RYR2)
TMU: 101346209
MDO: 100028207(RYR2)
SHR: 100916914(RYR2)
OAA: 100084273(RYR2)
GGA: 421508(RYR2)
MGP: 100551096(RYR2)
CJO: 107311396(RYR2)
APLA: 101793907(RYR2)
ACYG: 106048956(RYR2)
TGU: 100225109(RYR2)
GFR: 102039305(RYR2)
FAB: 101815198(RYR2)
PHI: 102105661(RYR2)
PMAJ: 107201934(RYR2)
CCW: 104684437(RYR2)
FPG: 101913442(RYR2)
FCH: 102053979(RYR2)
CLV: 102091036(RYR2)
AAM: 106485406(RYR2)
ASN: 102379736(RYR2)
AMJ: 102572051(RYR2)
PSS: 102449862(RYR2)
CMY: 102931487(RYR2)
CPIC: 101950679(RYR2)
ACS: 100555710(ryr2)
PVT: 110076303(RYR2)
PBI: 103059179(RYR2)
GJA: 107120023
DRE: 100126126(ryr2a) 568463(ryr2b)
SANH: 107668588 107674386(ryr2)
IPU: 108269589 108274087(ryr2)
AMEX: 103025966(ryr2) 103027186
LCO: 104919544 104924325(ryr2)
MZE: 101465081 101474189(ryr2)
XMA: 102235428(ryr2) 102238415
PRET: 103476718 103482120(ryr2)
CSEM: 103382205(ryr2) 103387261
LCF: 108876764(ryr2) 108897382
SASA: 106577062
ELS: 105010552 105025293(ryr2)
SFM: 108939633(ryr2)
LCM: 102353265(RYR2)
CMK: 103178965(ryr2)
CIN: 100178148(ryr2)
SPU: 580223
APLC: 110986867
SKO: 100328999(RYR)
DME: Dmel_CG10844(RyR)
DSI: Dsimw501_GD10606(Dsim_GD10606)
MDE: 101888405
AAG: 5579122
AME: 408680(RyR)
BIM: 100749661
BTER: 100643070
SOC: 105195231
AEC: 105146428
ACEP: 105626523
PBAR: 105431823
HST: 105188290
CFO: 105252243
LHU: 105669060
PGC: 109853394
NVI: 100118800
TCA: 655265
DPA: 109544790
NVL: 108563731
BMOR: 101739070
PMAC: 106707973
PXY: 105388065(Ryr)
API: 100167965
DNX: 107164288
FCD: 110843639
TUT: 107361086
CEL: CELE_K11C4.5(unc-68)
CBR: CBG19042(Cbr-unc-68)
BMY: Bm1_45145
TSP: Tsp_02477
CRG: 105333338
OBI: 106881762
AQU: 100637092
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8809036
  Authors
Tunwell RE, Wickenden C, Bertrand BM, Shevchenko VI, Walsh MB, Allen PD, Lai FA
  Title
The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis.
  Journal
Biochem J 318 ( Pt 2):477-87 (1996)
DOI:10.1042/bj3180477
  Sequence
[hsa:6262]

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