KEGG ORTHOLOGY: K04994

ORTHOLOGY: K04994

Entry

K04994                      KO

Symbol

MCOLN3, TRPML3

Name

mucolipin 3

Pathway

map04020

Calcium signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04994  MCOLN3, TRPML3; mucolipin 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04994  MCOLN3, TRPML3; mucolipin 3
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04994  MCOLN3, TRPML3; mucolipin 3

Other DBs

GO:

0005262

TC:	1.A.5.3.2 1.A.5.3.4

Genes

HSA:	55283(MCOLN3)

PTR:	469371(MCOLN3)

PPS:	100975689(MCOLN3)

GGO:	101142795(MCOLN3)

PON:	100447374(MCOLN3)

NLE:	100591172(MCOLN3)

HMH:	116469831(MCOLN3)

MCC:	710987(MCOLN3)

MCF:	102140305(MCOLN3)

MTHB:

126963574

MNI:	105482761(MCOLN3)

CSAB:

103224522(MCOLN3)

CATY:

105593577(MCOLN3)

PANU:

101002401(MCOLN3)

TGE:	112632130(MCOLN3)

MLEU:

105541199(MCOLN3)

RRO:	104677503(MCOLN3)

RBB:	108514774(MCOLN3)

TFN:	117092178(MCOLN3)

PTEH:

111539499(MCOLN3)

CANG:

105521792(MCOLN3)

CJC:	100412379(MCOLN3)

SBQ:	101043691(MCOLN3)

CIMI:

108283476(MCOLN3)

CSYR:

103267193(MCOLN3)

MMUR:

105861810(MCOLN3)

LCAT:

123635463(MCOLN3)

PCOQ:

105823812(MCOLN3)

OGA:	100962637(MCOLN3)

MMU:	171166(Mcoln3)

MCAL:

110291344(Mcoln3)

MPAH:

110320322(Mcoln3)

RNO:	308022(Mcoln3)

MCOC:

116093914(Mcoln3)

ANU:	117706968(Mcoln3)

MUN:	110558305(Mcoln3)

CGE:	100753377(Mcoln3)

MAUA:

101828749(Mcoln3)

PROB:

127229900(Mcoln3)

PLEU:

114698276(Mcoln3)

MORG:

121450283(Mcoln3)

MFOT:

126512405

AAMP:

119801114(Mcoln3)

NGI:	103728130(Mcoln3)

HGL:	101714807(Mcoln3)

CPOC:

100735790(Mcoln3)

CCAN:

109699394(Mcoln3)

DORD:

105987168(Mcoln3)

DSP:	122112378(Mcoln3)

PLOP:

125355351(Mcoln3)

NCAR:

124992963

OCU:

100340415

OPI:	101532036(MCOLN3)

TUP:	102491704(MCOLN3)

GVR:	103599686(MCOLN3)

CFA:	490185(MCOLN3)

CLUD:

112640966(MCOLN3)

VVP:	112924487(MCOLN3)

VLG:	121488251(MCOLN3)

NPO:	129519901(MCOLN3)

AML:	100472258(MCOLN3)

UMR:	103662962(MCOLN3)

UAH:	113254477(MCOLN3)

UAR:	123795263(MCOLN3)

ELK:

111143331

LLV:

125098633

NVS:	122900141(MCOLN3)

ORO:	101362389(MCOLN3)

EJU:	114208412(MCOLN3)

ZCA:	113928032(MCOLN3)

MLX:	118019212(MCOLN3)

NSU:	110580422(MCOLN3)

LWW:

102737900

FCA:	101098646(MCOLN3)

PYU:	121027396(MCOLN3)

PCOO:

112871827(MCOLN3)

PBG:	122480713(MCOLN3)

LRUF:

124516115

PTG:	102967486(MCOLN3)

PPAD:

109246193(MCOLN3)

PUC:

125913391

AJU:

106973318

HHV:	120241652(MCOLN3)

BTA:	514345(MCOLN3)

BOM:	102275761(MCOLN3)

BIU:	109556124(MCOLN3)

BBUB:

102415184(MCOLN3)

BBIS:

105003266(MCOLN3)

CHX:	102189726(MCOLN3)

OAS:	101111919(MCOLN3)

BTAX:

128044808(MCOLN3)

ODA:	120856935(MCOLN3)

CCAD:

122436757(MCOLN3)

MBEZ:

129541482(MCOLN3)

SSC:	100625693(MCOLN3)

CFR:	102523957(MCOLN3)

CBAI:

105075485(MCOLN3)

CDK:	105095049(MCOLN3)

VPC:	102525038(MCOLN3)

BACU:

103015262(MCOLN3)

LVE:	103073589(MCOLN3)

OOR:	101278762(MCOLN3)

DLE:	111178306(MCOLN3)

PCAD:

102994758(MCOLN3)

PSIU:

116760500(MCOLN3)

NASI:

112415078(MCOLN3)

ECB:	100064441(MCOLN3)

EPZ:	103562994(MCOLN3)

EAI:	106824056(MCOLN3)

MYB:	102246669(MCOLN3)

MYD:	102759917(MCOLN3)

MMYO:

118676981(MCOLN3)

MLF:	102417678(MCOLN3)

MNA:	107543204(MCOLN3)

PKL:	118723865(MCOLN3)

EFUS:

103284167(MCOLN3)

HAI:	109372902(MCOLN3)

DRO:	112309317(MCOLN3)

SHON:

118997358(MCOLN3)

AJM:	119062901(MCOLN3)

PDIC:

114497304(MCOLN3)

PHAS:

123816483(MCOLN3)

MMF:	118626405(MCOLN3)

RFQ:	117027211(MCOLN3)

PALE:

102881051(MCOLN3)

PGIG:

120583285(MCOLN3)

PVP:	105289075(MCOLN3)

RAY:	107511575(MCOLN3)

MJV:	108403890(MCOLN3)

TOD:	119236115(MCOLN3)

SARA:

101537622(MCOLN3)

LAV:	100655549(MCOLN3)

TMU:

101346348

ETF:	101647809(MCOLN3)

DNM:	101423815(MCOLN3)

MDO:	100012247(MCOLN3)

GAS:	123245280(MCOLN3)

SHR:	100915340(MCOLN3)

AFZ:

127563035

PCW:	110209940(MCOLN3)

OAA:	100092028(MCOLN3)

GGA:	429091(MCOLN3)

PCOC:

116233252(MCOLN3)

MGP:	100550246(MCOLN3)

CJO:	107317564(MCOLN3)

TPAI:

128072631(MCOLN3)

LMUT:

125694010(MCOLN3)

NMEL:

110391066(MCOLN3)

APLA:

101794809(MCOLN3)

ACYG:

106034096(MCOLN3)

CATA:

118243327(MCOLN3)

AFUL:

116492242(MCOLN3)

TGU:	100218399(MCOLN3)

LSR:	110468719(MCOLN3)

SCAN:

103814915

PMOA:

120510849

OTC:	121345148(MCOLN3)

PRUF:

121362149(MCOLN3)

GFR:	102041739(MCOLN3)

FAB:	101809471(MCOLN3)

OMA:	130256317(MCOLN3)

PHI:	102110762(MCOLN3)

PMAJ:

107208165(MCOLN3)

CCAE:

111932846(MCOLN3)

CCW:

104695309

CBRC:

103612617(MCOLN3)

ETL:	114057097(MCOLN3)

ZAB:	102066236(MCOLN3)

ACHL:

103808618(MCOLN3)

SVG:	106857553(MCOLN3)

MMEA:

130578483(MCOLN3)

HRT:	120756394(MCOLN3)

FPG:	101922956(MCOLN3)

FCH:	102053898(MCOLN3)

CLV:	102096077(MCOLN3)

EGZ:	104122923(MCOLN3)

NNI:	104015471(MCOLN3)

PCRI:

104027023(MCOLN3)

PLET:

104614289(MCOLN3)

EHS:

104505660

PCAO:

104039771(MCOLN3)

ACUN:

113483129(MCOLN3)

TALA:

104355482(MCOLN3)

PADL:

103925141(MCOLN3)

AFOR:

103894632(MCOLN3)

ACHC:

115348691(MCOLN3)

HALD:

104310776(MCOLN3)

HLE:	104841122(MCOLN3)

AGEN:

126042323

GCL:

127018985

CCRI:

104161047(MCOLN3)

CSTI:

104554990(MCOLN3)

CMAC:

104476767(MCOLN3)

MUI:	104533955(MCOLN3)

BREG:

104629747(MCOLN3)

FGA:	104069948(MCOLN3)

GSTE:

104251012(MCOLN3)

LDI:	104340462(MCOLN3)

MNB:	103780777(MCOLN3)

OHA:	104338839(MCOLN3)

NNT:	104399712(MCOLN3)

SHAB:

115611519(MCOLN3)

DPUB:

104300114(MCOLN3)

PGUU:

104465402(MCOLN3)

ACAR:

104520250

CPEA:

104396733(MCOLN3)

AVIT:

104272996(MCOLN3)

CVF:	104286153(MCOLN3)

CUCA:

104055201(MCOLN3)

TEO:	104376920(MCOLN3)

BRHI:

104501038(MCOLN3)

AAM:	106499644(MCOLN3)

AROW:

112961911(MCOLN3)

NPD:

112946242

DNE:	112993094(MCOLN3)

SCAM:

104142996(MCOLN3)

ASN:

102369420

AMJ:	102559049(MCOLN3)

CPOO:

109307334(MCOLN3)

GGN:	109286799(MCOLN3)

PSS:	102450477(MCOLN3)

CMY:	102933595(MCOLN3)

CCAY:

125640818(MCOLN3)

DCC:	119860692(MCOLN3)

CPIC:

101940827(MCOLN3)

TST:	117881594(MCOLN3)

CABI:

116835754(MCOLN3)

MRV:	120370953(MCOLN3)

ACS:	100554956(mcoln3)

PVT:	110079755(MCOLN3)

PBI:	103062357(MCOLN3)

PMUR:

107285236(MCOLN3)

CTIG:

120297881(MCOLN3)

TSR:	106553750(MCOLN3)

PGUT:

117677140(MCOLN3)

APRI:

131195662(MCOLN3)

PTEX:

113436079(MCOLN3)

NSS:	113416338(MCOLN3)

VKO:	123024566(MCOLN3)

PMUA:

114598803(MCOLN3)

PRAF:

128415561(MCOLN3)

ZVI:	118089025(MCOLN3)

HCG:	128322084(MCOLN3)

GJA:	107109796(MCOLN3)

STOW:

125433661(MCOLN3)

EMC:	129330238(MCOLN3)

XLA:	108713519 108715492 444109(mcoln3.S)

XTR:	549558(mcoln3)

NPR:	108791382(MCOLN3)

RTEM:

120945966(MCOLN3)

BBUF:

120979274(MCOLN3)

BGAR:

122943143(MCOLN3)

MUO:	115472175(MCOLN3)

GSH:	117346644(MCOLN3)

DRE:	100001113(mcoln3b) 100334819(mcoln3a)

SRX:	107705102 107740683

SANH:

107660413 107660957

SGH:	107570656(mcoln3) 107573859

CCAR:

109048045(mcoln3)

CAUA:

113041358 113046133

CGIB:

127950582 128011062

PTET:

122332892(mcoln3b) 122359876(mcoln3a)

LROH:

127154322(mcoln3b) 127181741(mcoln3a)

OMC:	131529038(mcoln3a) 131532030(mcoln3b)

PPRM:

120463762(mcoln3b) 120477293 120481065(mcoln3a)

MAMB:

125250033(mcoln3a) 125260063(mcoln3b)

CIDE:

127498640 127505562

MASI:

127419748 127440758 127441945

TROS:

130545084(mcoln3b) 130554179(mcoln3a)

IPU:	108268238(mcoln3a) 108276449(mcoln3b)

PHYP:

113530809(mcoln3)

SMEO:

124388014 124398610(mcoln3b)

TFD:	113639201(mcoln3b) 113640177

AMEX:

103027252(mcoln3) 103030323

CMAO:

118823015(mcoln3b) 118826319(mcoln3a)

EEE:	113590509 113591484

CHAR:

105907754(mcoln3b) 122130295(mcoln3a)

TRU:	101068189 101068866

TFS:	130528891(mcoln3b) 130539071(mcoln3a)

TNG:	GSTEN00027655G001 GSTEN00033549G001

LCO:	104917715 104930563

NCC:	104946462 104953893

CGOB:

115006887 115023097

ELY:	117254217(mcoln3b) 117271930(mcoln3a)

EFO:	125895808(mcoln3b) 125902277(mcoln3a)

PLEP:

121951470(mcoln3a) 121964222(mcoln3b)

SLUC:

116039104(mcoln3b) 116046216(mcoln3a)

ECRA:

117950374(mcoln3b) 117953730(mcoln3a)

ESP:	116695404(mcoln3) 116699806

PFLV:

114561148 114565951

GAT:	120815671(mcoln3a) 120824200(mcoln3b)

PPUG:

119209787(mcoln3a) 119216768(mcoln3b)

AFB:	129088768(mcoln3a) 129094293(mcoln3b)

CLUM:

117729336(mcoln3b)

MSAM:

119887241 119898476 119900375(mcoln3b)

SCHU:

122878323(mcoln3b) 122886551(mcoln3a)

CUD:	121512031(mcoln3b) 121520352

ALAT:

119011658(mcoln3a) 119028199(mcoln3b)

MZE:	101473080 101483405(mcoln3)

ONL:	100693840 100694709(mcoln3)

OAU:	116315320 116336362(mcoln3b)

OLA:	101157647 101169350

OML:	112147475(mcoln3a) 112150326(mcoln3b)

XMA:	102226928(mcoln3) 102232969

XCO:	114146045 114151055

XHE:

116726029

PRET:

103463081(mcoln3) 103479861

PFOR:

103135719 103137192(mcoln3)

PLAI:

106958893 106960105

PMEI:

106924529 106930784

GAF:	122838259(mcoln3b) 122841053(mcoln3a)

CVG:	107081686 107089208

CTUL:

119784877(mcoln3b) 119794155(mcoln3a)

GMU:	124870649 124874025(mcoln3b)

NFU:	107383824 107392950

KMR:	108238441(mcoln3b) 108241664(mcoln3a)

ALIM:

106528257 106532920

NWH:	119414691 119430582(mcoln3b)

AOCE:

111563968 111567689

MCEP:

125009610(mcoln3b) 125011106(mcoln3a)

CSEM:

103396193 103396360

POV:	109636636 109637159

SSEN:

122759985 122779503(mcoln3a) 122780887(mcoln3b)

HHIP:

117759744(mcoln3b) 117777721(mcoln3a)

HSP:	118118272(mcoln3a) 118121094(mcoln3b)

LCF:	108883324(mcoln3a) 108895293(mcoln3b)

SDU:	111218765 111230971

SLAL:

111645367 111652942

XGL:	120790572(mcoln3b) 120798980(mcoln3a)

HCQ:	109524068 109530525

SSCV:

125976134 125985004

BPEC:

110164095 110172277

MALB:

109955419 109961683

BSPL:

114843951(mcoln3a) 114854269(mcoln3b)

SASA:

106560446 106599955

STRU:

115158699 115169546

OTW:	112226760(mcoln3a) 112246489(mcoln3b)

OMY:	110508541(mcoln3a) 110524709(mcoln3b)

OGO:	123996674(mcoln3b) 124041715(mcoln3a)

ONE:	115101758 115108643

OKI:	109872057 109902828

SALP:

111975987 111979435

SNH:	120020648(mcoln3a) 120054556(mcoln3b)

CCLU:

121533837(mcoln3b) 121581544(mcoln3a)

ELS:	105020087 105029004(mcoln3)

SFM:	108923473 114911273

PKI:	111847519 111860457(mcoln3)

AANG:

118224887(mcoln3b) 118228868

LOC:	102692019(mcoln3)

PSPA:

121330662(mcoln3b)

ARUT:

117404088

LCM:	102362398(MCOLN3)

CMK:

103174696

RTP:

109922856

CPLA:

122554737(mcoln3b)

LERI:

129693506 129694056(mcoln3b)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG42638(CG42638) Dmel_CG8743(Trpml)

DER:

6545482

DSE:

6619392

DSI:	Dsimw501_GD12254(Dsim_GD12254)

DYA:	Dyak_GE27849

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11846

DNV:

DHE:

DVI:

CCAT:

BOD:

RZE:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

HIS:

AGA:	AgaP_AGAP007710

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ011507

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

TCA:	655074(TRPL)

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212315

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105391226 105393299

PGW:

CFEL:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

PHU:	Phum_PHUM586230

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

IEL:

FCD:

DPX:	DAPPUDRAFT_198851

DMK:

DPZ:

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

ESN:	126993367 126998526

HAZT:

EAF:

LSM:

PPOI:

ISC:	IscW_ISCW001660

DSV:	119460663 119460666

RSAN:

119396548 119396549

RMP:	119174724 119174726

VDE:	111243673 111247376

VJA:	111260774 111264891

TUT:	107362069 107362100 107363391

DPTE:

113789822 113791613

DFR:	124499432 124500033

CSCU:

111624228

PTEP:

107441352 107444661

UDV:	129216906 129228677 129232246 129232542

SDM:	118193124 118197618

LPOL:

106473793

PMEO:

129594122

CEL:	CELE_R13A5.1(cup-5)

CBR:	CBG_09148(Cbr-cup-5)

BMY:	BM_BM5376(Bma-cup-5)

LOA:	LOAG_04987

NAI:	NECAME_13244

TSP:

Tsp_10515

HRO:	HELRODRAFT_90253

LGI:	LOTGIDRAFT_118439

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111121173 111134182 111134955 111138101

CANU:

128165257

OED:

125669202

MYI:	110443401 110450598 110463669

PMAX:

117326316 117331382 117344211

MCAF:

127737427

MMER:

123524410 123529265 123531835 123531846 123531854 123549597 123549602 123549605 123562165

DPOL:

127859568 127859572 127877409 127879983 127879984

OBI:

106873383

OSN:

115213883

LAK:	106162482 106162483 106174828 106174914 106174915

SMM:	Smp_190090

SHX:	MS3_00008932

OVI:	T265_07823

NVE:	5514422 5514459

EPA:	110237418 110254527

ATEN:

116288470

ADF:	107340687 107340688

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130628806 130629380 130629425

TAD:	TRIADDRAFT_27592

AQU:

105311917

MBR:	MONBRDRAFT_5126

SRE:	PTSG_06359

DFA:

DFA_03651

TET:	TTHERM_00191760

PIF:	PITG_21149

PSOJ:

PHYSODRAFT_526427

SPAR:

SPRG_06267

» show all

Reference

PMID:12403827

Authors

Di Palma F, Belyantseva IA, Kim HJ, Vogt TF, Kachar B, Noben-Trauth K

Title

Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice.

Journal

Proc Natl Acad Sci U S A 99:14994-9 (2002)
DOI:10.1073/pnas.222425399

Sequence

[mmu:171166]

All links

Ontology (5)   
   KEGG BRITE (2)   
   GO (1)   
   TC (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (2040)   
   KEGG GENES (731)   
   KEGG MGENES (142)   
   RefGene (1161)   
   OC (6)   
Literature (1)   
   PubMed (1)   
All databases (2048)   

Download RDF

DBGET integrated database retrieval system