KEGG   ORTHOLOGY: K05031Help
Entry
K05031                      KO                                     

Name
CFTR, ABCC7
Definition
cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49]
Pathway
ko02010  ABC transporters
ko04024  cAMP signaling pathway
ko04152  AMPK signaling pathway
ko04530  Tight junction
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko04976  Bile secretion
ko05110  Vibrio cholerae infection
Disease
H00218  Cystic fibrosis (CF)
H00933  Hereditary pancreatitis
H01033  Congenital bilateral absence of vas deferens
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Membrane transport
   02010 ABC transporters
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
  Signal transduction
   04024 cAMP signaling pathway
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
   04152 AMPK signaling pathway
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
 Cellular Processes
  Cellular community - eukaryotes
   04530 Tight junction
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
 Organismal Systems
  Digestive system
   04971 Gastric acid secretion
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
   04972 Pancreatic secretion
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
   04976 Bile secretion
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
 Human Diseases
  Infectious diseases
   05110 Vibrio cholerae infection
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.3  Acting on acid anhydrides to catalyse transmembrane movement of substances
    3.6.3.49  channel-conductance-controlling ATPase
     K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
Transporters [BR:ko02000]
 ABC Transporters, Eukaryotic Type
  ABCC (CFTR/MRP) subfamily
   ABCC7 subgroup
    K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator
BRITE hierarchy
Other DBs
GO: 0005260
TC: 3.A.1.202
Genes
HSA: 1080(CFTR)
PTR: 463674(CFTR)
PPS: 100989405(CFTR)
GGO: 101132066(CFTR)
PON: 100137035(CFTR)
NLE: 100601480(CFTR)
MCC: 574346(CFTR)
MCF: 102130331(CFTR)
CSAB: 103226777(CFTR)
RRO: 104682625(CFTR)
RBB: 108526537(CFTR)
CJC: 100415251(CFTR)
SBQ: 101036459(CFTR)
MMU: 12638(Cftr)
RNO: 24255(Cftr)
CGE: 100754506(Cftr)
NGI: 103737361(Cftr)
HGL: 101709472(Cftr)
CCAN: 109679300(Cftr) 109680514
OCU: 100009471(CFTR)
TUP: 102490714(CFTR)
CFA: 492302(CFTR)
AML: 100478723(CFTR)
UMR: 103676590(CFTR)
ORO: 101363648(CFTR)
FCA: 492308(CFTR)
PTG: 102956215(CFTR)
AJU: 106970664(CFTR)
BTA: 281067(CFTR)
BOM: 102264773(CFTR) 102266351
BIU: 109557891(CFTR)
PHD: 102332344(CFTR)
CHX: 102179446(CFTR)
OAS: 443347(CFTR)
SSC: 403154(CFTR)
CFR: 102505598(CFTR)
CDK: 105085325(CFTR)
BACU: 103004581(CFTR)
LVE: 103088529(CFTR)
OOR: 101278319(CFTR)
ECB: 100071259(CFTR)
EPZ: 103550601(CFTR)
EAI: 106829379(CFTR)
MYB: 102257625(CFTR)
MYD: 102773631(CFTR)
HAI: 109376431
RSS: 109453461(CFTR)
PALE: 102884577(CFTR)
LAV: 100662653(CFTR)
TMU: 101346801
MDO: 100014119(CFTR)
SHR: 100919086(CFTR)
OAA: 100078764(CFTR)
GGA: 100049619(CFTR)
MGP: 100545354(CFTR)
CJO: 107309076(CFTR)
APLA: 101803386(CFTR)
ACYG: 106042053(CFTR)
TGU: 100222243(CFTR)
GFR: 102041165(CFTR)
FAB: 101809710(CFTR)
PHI: 102114534(CFTR)
PMAJ: 107205064(CFTR)
CCW: 104698445(CFTR)
FPG: 101921929(CFTR)
FCH: 102050923(CFTR)
CLV: 102089481(CFTR)
EGZ: 104133415(CFTR)
AAM: 106488125(CFTR)
ASN: 102369471(CFTR)
AMJ: 102563163(CFTR)
PSS: 102447829(CFTR)
CMY: 102936252(CFTR)
CPIC: 101933840(CFTR)
ACS: 100559531(cftr)
PVT: 110077041(CFTR)
PBI: 103057487(CFTR)
GJA: 107114507(CFTR)
XLA: 108712361 373725(cftr-A)
XTR: 100486085(cftr)
NPR: 108802076(CFTR)
DRE: 559080(cftr)
SANH: 107660943(cftr) 107672176
CCAR: 109110485(cftr) 109110487
IPU: 108264684(cftr)
AMEX: 103032690(cftr)
TRU: 492310(cftr)
LCO: 104925520(cftr)
MZE: 101473042(cftr)
OLA: 101161380(cftr)
XMA: 102231389(cftr)
PRET: 103465638(cftr)
NFU: 107388351(cftr)
CSEM: 103379580(cftr)
LCF: 108893910(cftr)
HCQ: 109530830(cftr) 109530831
BPEC: 110155111(cftr)
ELS: 105029518(cftr)
SFM: 108931616(cftr)
LCM: 102346483(CFTR)
CMK: 103179362(cftr)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2475911
  Authors
Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z, Zielenski J, Lok S, Plavsic N, Chou JL, et al.
  Title
Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.
  Journal
Science 245:1066-73 (1989)
DOI:10.1126/science.2475911
  Sequence
[hsa:1080]

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