KEGG   ORTHOLOGY: K05055Help
Entry
K05055                      KO                                     

Name
IL6R, CD126
Definition
interleukin 6 receptor
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04630  Jak-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04659  Th17 cell differentiation
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
   04066 HIF-1 signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
   04151 PI3K-Akt signaling pathway
    K05055  IL6R, CD126; interleukin 6 receptor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05055  IL6R, CD126; interleukin 6 receptor
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05055  IL6R, CD126; interleukin 6 receptor
   04659 Th17 cell differentiation
    K05055  IL6R, CD126; interleukin 6 receptor
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05055  IL6R, CD126; interleukin 6 receptor
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K05055  IL6R, CD126; interleukin 6 receptor
  Infectious diseases
   05163 Human cytomegalovirus infection
    K05055  IL6R, CD126; interleukin 6 receptor
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05055  IL6R, CD126; interleukin 6 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05055  IL6R, CD126; interleukin 6 receptor
CD molecules [BR:ko04090]
 Proteins
  K05055  CD126, IL6R; interleukin 6 receptor
BRITE hierarchy
Other DBs
GO: 0004915
Genes
HSA: 3570(IL6R)
PTR: 469506(IL6R)
PPS: 100972031(IL6R)
GGO: 101130311(IL6R)
PON: 100459702(IL6R)
NLE: 100604063(IL6R)
MCC: 716690(IL6R)
MCF: 102116430(IL6R)
CSAB: 103223920(IL6R)
RRO: 104663493(IL6R)
RBB: 108526613(IL6R)
CJC: 100385661(IL6R)
SBQ: 101037958(IL6R)
MMU: 16194(Il6ra)
RNO: 24499(Il6r)
CGE: 100750971(Il6r)
NGI: 103751364(Il6r)
HGL: 101704925(Il6r)
CCAN: 109688039(Il6r)
OCU: 100347752(IL6R)
TUP: 102492996(IL6R)
CFA: 612271(IL6R)
AML: 100471277(IL6R)
UMR: 103668717(IL6R)
ORO: 101368251(IL6R)
FCA: 101085689(IL6R)
PTG: 102951407(IL6R)
AJU: 106987238(IL6R)
BTA: 507359(IL6R)
BOM: 102287439(IL6R)
BIU: 109554138(IL6R)
PHD: 102337991(IL6R)
CHX: 102179824(IL6R)
OAS: 101103369(IL6R)
SSC: 399522(IL6R)
CFR: 102511771(IL6R)
CDK: 105089663(IL6R)
BACU: 103019388(IL6R)
LVE: 103078095(IL6R)
OOR: 101274728(IL6R)
ECB: 102148787(IL6R)
EPZ: 103555416(IL6R)
EAI: 106828529(IL6R)
MYB: 102242151(IL6R)
MYD: 102757197(IL6R)
HAI: 109373511(IL6R)
RSS: 109435410(IL6R)
PALE: 102878027(IL6R)
LAV: 100664198(IL6R)
TMU: 101356003
MDO: 100020561(IL6R)
SHR: 100924664(IL6R)
GGA: 693252(IL6R)
MGP: 104917170(IL6R)
CJO: 107324499(IL6R)
TGU: 100231725(IL6R)
GFR: 102038301(IL6R)
FAB: 101821627(IL6R)
PHI: 102105213(IL6R)
PMAJ: 107214583(IL6R)
CCW: 104683111(IL6R)
FPG: 101910354(IL6R)
AMJ: 102569548(IL6R)
CMY: 102929351(IL6R)
CPIC: 101947969(IL6R)
ACS: 103281452(il6r)
PVT: 110081055(IL6R)
PBI: 103050892(IL6R)
GJA: 107117068(IL6R)
XTR: 100491081(il6r)
NPR: 108802740(IL6R)
DRE: 100135755(il6r)
IPU: 108266000(IL6R) 108266011
AMEX: 103028913(il6r)
TRU: 101069438(il6r)
LCO: 104934469
NCC: 104959175
MZE: 101486162
OLA: 101173653
XMA: 102233430
PRET: 103478148
CSEM: 103388203
LCF: 108885967
HCQ: 109529023
BPEC: 110163064
SASA: 100380426(il6ra) 106595086(IL6RA)
ELS: 105024482
SFM: 108923935(il6r)
LCM: 102359769(IL6R)
CMK: 103172814(il6r)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1872801
  Authors
Schooltink H, Stoyan T, Lenz D, Schmitz H, Hirano T, Kishimoto T, Heinrich PC, Rose-John S
  Title
Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells.
  Journal
Biochem J 277 ( Pt 3):659-64 (1991)
DOI:10.1042/bj2770659
  Sequence
[hsa:3570]

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