KEGG   ORTHOLOGY: K05066
Entry
K05066                      KO                                     
Symbol
CSF2RA, GMCSFR, CD116
Name
granulocyte-macrophage colony-stimulating factor receptor alpha
Pathway
map04060  Cytokine-cytokine receptor interaction
map04630  JAK-STAT signaling pathway
map04640  Hematopoietic cell lineage
map05200  Pathways in cancer
Disease
H01122  Congenital pulmonary alveolar proteinosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
   04090 CD molecules
    K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL3 receptor family
   K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
CD molecules [BR:ko04090]
 Proteins
  K05066  CD116, CSF2RA; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Genes
HSA: 1438(CSF2RA)
PTR: 746936(CSF2RA)
PON: 100452320 100452697
NLE: 100596513 100602399 100605652 115834049 115834378
MCF: 102139775(CSF2RA)
CSAB: 103247514(CSF2RA)
CATY: 105590318(CSF2RA)
TGE: 112615949(CSF2RA)
RRO: 104663344(CSF2RA)
RBB: 108524070
TFN: 117076099(CSF2RA)
PTEH: 113220732
CJC: 100413917(CSF2RA) 100894193
SBQ: 101038788(CSF2RA)
MMUR: 105870809(CSF2RA) 105870818
OGA: 100945167(CSF2RA)
MMU: 12982(Csf2ra)
MCAL: 110285238
MPAH: 110315436
RNO: 652957(Csf2ra)
MCOC: 116075238
MUN: 110566611
CGE: 113833669
PLEU: 114682475
NGI: 103750113
HGL: 101702638
DORD: 106001744
DSP: 122106852
NCAR: 124972637
OCU: 100346676(CSF2RA)
OPI: 101531536(CSF2RA)
TUP: 102476450(CSF2RA)
CFA: 100686341 609266(CSF2RA)
VLG: 121482308(CSF2RA) 121483170
AML: 100469756(CSF2RA) 105238364
UMR: 103666290(CSF2RA) 103666329
UAH: 113240792 113240793(CSF2RA)
UAR: 123802758(CSF2RA)
LLV: 125092117
MPUF: 101672208(CSF2RA) 101683998
ORO: 101383473(CSF2RA) 105757391
MLX: 118026665(CSF2RA) 118026666
PYU: 121020164
PBG: 122476983(CSF2RA) 122477816
PTG: 102966764(CSF2RA)
BTA: 100336606(CSF2RA)
BOM: 102279567(CSF2RA)
BIU: 109568669
BBUB: 102408349(CSF2RA)
CHX: 102175201(CSF2RA)
OAS: 101115509
ODA: 120882426
CCAD: 122434354
SSC: 100620339(CSF2RA)
CFR: 102511890(CSF2RA)
CBAI: 105079511
CDK: 105103092
VPC: 102540989(CSF2RA)
BACU: 103005794(CSF2RA)
LVE: 103083689(CSF2RA)
OOR: 101280976(CSF2RA)
DLE: 111168273(CSF2RA)
PCAD: 102987016(CSF2RA)
PSIU: 116746993(CSF2RA)
ECB: 102148014
EPZ: 103545274
EAI: 106842472(IL3RA) 106842481(CSF2RA)
MYB: 102246112(CSF2RA) 106725951
MMYO: 118657306 118657314(CSF2RA)
MNA: 107543956 107543958(CSF2RA)
HAI: 109375576(CSF2RA)
DRO: 112313318(CSF2RA)
SHON: 118974340(CSF2RA) 118974345
AJM: 119045499 119045760(CSF2RA)
PHAS: 123830036(CSF2RA)
MMF: 118636238 118636251(CSF2RA)
RFQ: 117028565
PALE: 102878494
PGIG: 120596738(CSF2RA)
PVP: 105308006
MJV: 108389768 108389965(CSF2RA)
TOD: 119246374(CSF2RA)
LAV: 100664139(CSF2RA) 111749385
MDO: 103094977(CSF2RA)
GAS: 123241728
SHR: 105749994(CSF2RA)
PCW: 110212746(CSF2RA)
GGA: 101747500(GMSRAL) 418666(CSF2RA)
AMJ: 102557808(CSF2RA) 102558040
CMY: 102940756
CPIC: 101938142
TST: 117870478
ACS: 103278321(csf2ra)
PVT: 110089754
SUND: 121925608
PBI: 103051752
PMUR: 107289685
TSR: 106547818
PGUT: 117673789
VKO: 123024742
PMUA: 114596328
ZVI: 118085219
GJA: 107120384
STOW: 125430488
KMR: 108238321
ALIM: 106517882
POV: 109642109
SDU: 111229143
XGL: 120799514
HCQ: 109520534
SASA: 106569469
OTW: 112260783
OMY: 110530632
CMK: 103177101
 » show all
Reference
PMID:2555171
  Authors
Gearing DP, King JA, Gough NM, Nicola NA
  Title
Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.
  Journal
EMBO J 8:3667-76 (1989)
DOI:10.1002/j.1460-2075.1989.tb08541.x
  Sequence
[hsa:1438]
Reference
  Authors
Son BK, Sawaki D, Tomida S, Fujita D, Aizawa K, Aoki H, Akishita M, Manabe I, Komuro I, Friedman SL, Nagai R, Suzuki T
  Title
Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma.
  Journal
Nat Commun 6:6994 (2015)
DOI:10.1038/ncomms7994

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