KEGG   ORTHOLOGY: K05071Help
Entry
K05071                      KO                                     

Name
IL4R, CD124
Definition
interleukin 4 receptor
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04151  PI3K-Akt signaling pathway
ko04630  Jak-STAT signaling pathway
ko04640  Hematopoietic cell lineage
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05200  Pathways in cancer
ko05321  Inflammatory bowel disease (IBD)
Disease
H00079  Asthma
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
   04151 PI3K-Akt signaling pathway
    K05071  IL4R, CD124; interleukin 4 receptor
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05071  IL4R, CD124; interleukin 4 receptor
 Organismal Systems
  Immune system
   04640 Hematopoietic cell lineage
    K05071  IL4R, CD124; interleukin 4 receptor
   04658 Th1 and Th2 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
   04659 Th17 cell differentiation
    K05071  IL4R, CD124; interleukin 4 receptor
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05071  IL4R, CD124; interleukin 4 receptor
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K05071  IL4R, CD124; interleukin 4 receptor
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL2 receptor family
   K05071  IL4R, CD124; interleukin 4 receptor
CD molecules [BR:ko04090]
 Proteins
  K05071  CD124, IL4R; interleukin 4 receptor
BRITE hierarchy
Other DBs
GO: 0004913
Genes
HSA: 3566(IL4R)
PTR: 454005(IL4R)
PPS: 100969808(IL4R)
GGO: 101124934(IL4R)
PON: 100449812(IL4R)
NLE: 100606206(IL4R)
MCC: 705404(IL4R)
MCF: 102133649(IL4R)
CSAB: 103230069(IL4R)
RRO: 104665638(IL4R)
RBB: 108538856(IL4R)
CJC: 100412639(IL4R)
SBQ: 101044733(IL4R)
MMU: 16190(Il4ra)
RNO: 25084(Il4r)
CGE: 100762840(Il4r)
NGI: 103741011(Il4r)
HGL: 101704138(Il4r)
CCAN: 109698033(Il4r)
OCU: 100337721(IL4R)
TUP: 102469844(IL4R)
CFA: 489957(IL4R)
AML: 100476095(IL4R)
UMR: 103657902(IL4R)
ORO: 101373228(IL4R)
FCA: 101096277(IL4R)
PTG: 102949893(IL4R)
AJU: 106966182(IL4R)
BTA: 404154(IL4R)
BOM: 102273764(IL4R)
BIU: 109578521(IL4R)
PHD: 102337351(IL4R)
CHX: 102176382(IL4R)
OAS: 101109063(IL4R)
SSC: 397614(IL4R)
CFR: 102504937(IL4R)
CDK: 105098257(IL4R)
BACU: 103017383(IL4R)
LVE: 103085500(IL4R)
OOR: 101281237(IL4R)
ECB: 791252(IL4R)
EPZ: 103556347(IL4R)
EAI: 106829083(IL4R)
MYD: 102752440(IL4R) 102768492
HAI: 109385965(IL4R)
RSS: 109438291(IL4R)
PALE: 102882815(IL4R)
LAV: 100654822(IL4R)
TMU: 101351007
MDO: 103092514(IL4R)
SHR: 100922104(IL4R)
OAA: 103164911
GGA: 416585(IL4R)
MGP: 100541265(IL4R)
CJO: 107320714(IL4R)
APLA: 101796552(IL4R)
ACYG: 106046042(IL4R)
TGU: 100220266(IL4R)
GFR: 102032458(IL4R)
FAB: 101812385(IL4R)
PHI: 102114232(IL4R)
PMAJ: 107211179(IL4R)
CCW: 104684903(IL4R)
FPG: 101913747(IL4R)
FCH: 102059925(IL4R)
CLV: 102092650(IL4R)
EGZ: 104131347(IL4R)
AAM: 106486134(IL4R)
ASN: 102384900(IL4R)
AMJ: 102563749(IL4R)
PSS: 102459395(IL4R)
CMY: 102929479(IL4R)
CPIC: 101942260(IL4R)
ACS: 103281083(il4r)
PVT: 110085007
PBI: 103065038(IL4R)
XTR: 101732450(il4r) 105948365
DRE: 563674(il4r.2)
IPU: 108257347(il4r) 108280483
SASA: 100195064(il4ra) 106601108
ELS: 105013235(il4r)
SFM: 108932964
LCM: 102349939 106706712(IL4R)
CMK: 103186635(il4r)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2307934
  Authors
Idzerda RL, March CJ, Mosley B, Lyman SD, Vanden Bos T, Gimpel SD, Din WS, Grabstein KH, Widmer MB, Park LS, et al.
  Title
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
  Journal
J Exp Med 171:861-73 (1990)
DOI:10.1084/jem.171.3.861
  Sequence
[hsa:3566]
Reference
PMID:8124718
  Authors
Keegan AD, Nelms K, White M, Wang LM, Pierce JH, Paul WE
  Title
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth.
  Journal
Cell 76:811-20 (1994)
DOI:10.1016/0092-8674(94)90356-5

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