KEGG   ORTHOLOGY: K05094Help
Entry
K05094                      KO                                     

Name
FGFR3, CD333
Definition
fibroblast growth factor receptor 3 [EC:2.7.10.1]
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04144  Endocytosis
ko04151  PI3K-Akt signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04810  Regulation of actin cytoskeleton
ko05200  Pathways in cancer
ko05206  MicroRNAs in cancer
ko05219  Bladder cancer
ko05230  Central carbon metabolism in cancer
Disease
H00010  Multiple myeloma
H00022  Bladder cancer
H00458  Craniosynostosis
H00505  FGFR3-related short limb skeletal dysplasia
H00642  Lacrimo-auriculo-dento-digital syndrome (LADD)
H00997  CATSHL syndrome
H01749  Achondroplasia
H01750  Thanatophoric dysplasia
H01754  Crouzon syndrome
H01990  Muenke syndrome
H02068  Hypochondroplasia
H02069  SADDAN
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04015 Rap1 signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04010 MAPK signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   04151 PI3K-Akt signaling pathway
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05230 Central carbon metabolism in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05206 MicroRNAs in cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
   05219 Bladder cancer
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05094  FGFR3, CD333; fibroblast growth factor receptor 3
Protein kinases [BR:ko01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   K05094  FGFR3, CD333; fibroblast growth factor receptor 3
CD molecules [BR:ko04090]
 Proteins
  K05094  CD333, FGFR3; fibroblast growth factor receptor 3
BRITE hierarchy
Other DBs
GO: 0005007
Genes
HSA: 2261(FGFR3)
PTR: 461067(FGFR3)
PPS: 100976551(FGFR3)
GGO: 101139997(FGFR3)
PON: 100433126(FGFR3)
NLE: 100591839(FGFR3)
MCC: 712829(FGFR3)
MCF: 102128947(FGFR3)
CSAB: 103246479(FGFR3)
RRO: 104678934(FGFR3)
RBB: 108532286(FGFR3)
CJC: 100409938(FGFR3)
SBQ: 101051421(FGFR3)
MMU: 14184(Fgfr3)
RNO: 84489(Fgfr3)
CGE: 100764560(Fgfr3)
NGI: 103741127(Fgfr3)
HGL: 101711651(Fgfr3)
CCAN: 109695016(Fgfr3)
TUP: 102500041(FGFR3)
CFA: 488808(FGFR3)
AML: 100481826(FGFR3)
UMR: 103676958(FGFR3)
ORO: 101381434(FGFR3)
FCA: 100141386(FGFR3)
BTA: 281769(FGFR3)
BOM: 102264670(FGFR3)
BIU: 109560724(FGFR3)
PHD: 102325791(FGFR3)
CHX: 102187310(FGFR3)
OAS: 554324(FGFR3)
SSC: 100514115(FGFR3)
CFR: 102508259 102512878(FGFR3)
CDK: 105100875(FGFR3)
BACU: 103002473(FGFR3)
LVE: 103086424(FGFR3)
OOR: 101273169(FGFR3)
ECB: 100034114(FGFR3)
EPZ: 103556997(FGFR3)
EAI: 106830606(FGFR3)
HAI: 109390958(FGFR3)
RSS: 109434969(FGFR3) 109442995
PALE: 102878342(FGFR3)
LAV: 100674054(FGFR3)
TMU: 101341002
MDO: 100023287(FGFR3)
SHR: 100913979(FGFR3)
OAA: 100084071(FGFR3)
GGA: 396515(FGFR3)
MGP: 100543461(FGFR3)
CJO: 107313983(FGFR3)
APLA: 101804995(FGFR3)
ACYG: 106034332(FGFR3)
TGU: 100218924(FGFR3)
GFR: 102044988(FGFR3)
FAB: 101812160(FGFR3)
PHI: 102114034(FGFR3)
PMAJ: 107203422(FGFR3)
CCW: 104690922(FGFR3)
FPG: 101920747(FGFR3)
FCH: 102052231(FGFR3)
CLV: 102098275(FGFR3)
EGZ: 104130196(FGFR3)
AAM: 106498761(FGFR3)
ASN: 102371740(FGFR3)
AMJ: 106736800(FGFR3)
PSS: 102444715(FGFR3)
CMY: 102939991(FGFR3)
CPIC: 101933794(FGFR3)
PVT: 110085587(FGFR3)
PBI: 103067086(FGFR3)
GJA: 107122537
XLA: 399347(fgfr3.S) 779370(fgfr3.L)
XTR: 100196923(fgfr3)
NPR: 108788840(FGFR3)
DRE: 58129(fgfr3)
CCAR: 109098492
IPU: 108263592
AMEX: 103045058(fgfr3)
MZE: 101470524 101476450(fgfr3)
OLA: 100049424(fgfr3)
XMA: 102228238
PRET: 103458160
NFU: 107391665
CSEM: 103383204(fgfr3)
LCF: 108889150(fgfr3)
HCQ: 109520993(fgfr3)
BPEC: 110155643(fgfr3)
SFM: 108920925(fgfr3)
LCM: 102364583(FGFR3)
CMK: 103181516(fgfr3)
DME: Dmel_CG7223(htl)
DSI: Dsimw501_GD20204(Dsim_GD20204)
PXY: 105390898
FCD: 110854753
TUT: 107368562
OBI: 106873489
HMG: 100206525(FGFR) 100214111
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Terada M, Shimizu A, Sato N, Miyakaze SI, Katayama H, Kurokawa-Seo M
  Title
Fibroblast growth factor receptor 3 lacking the Ig IIIb and transmembrane domains secreted from human squamous cell carcinoma DJM-1 binds to FGFs.
  Journal
Mol Cell Biol Res Commun 4:365-73 (2001)
DOI:10.1006/mcbr.2001.0306
  Sequence
[hsa:2261]

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