KEGG   ORTHOLOGY: K05295
Entry
K05295                      KO                                     
Symbol
E1.1.1.149
Name
20alpha-hydroxysteroid dehydrogenase [EC:1.1.1.149]
Pathway
map00140  Steroid hormone biosynthesis
map01100  Metabolic pathways
Reaction
R02207  20alpha-hydroxy-4-pregnen-3-one:NAD+ 20-oxidoreductase
R02209  20alpha-hydroxy-4-pregnen-3-one:NADP+ 20-oxidoreductase
R03325  17alpha,20alpha-dihydroxypregn-4-en-3-one:NADP+ 20-oxidoreductase
R08958  5alpha-pregnan-20alpha-ol-3-one:NADP+ 20-oxidoreductase
R08959  5alpha-pregnane-3alpha,20alpha-diol:NADP+ 20-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K05295  E1.1.1.149; 20alpha-hydroxysteroid dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.149  20alpha-hydroxysteroid dehydrogenase
     K05295  E1.1.1.149; 20alpha-hydroxysteroid dehydrogenase
Other DBs
GO: 0047006
Genes
MMU: 105349(Akr1c18)
RNO: 171516(Akr1c3)
ANU: 117713814
CGE: 100768666
MAUA: 101841800
PROB: 127229811
MORG: 121432666
AAMP: 119816162
DORD: 105980417
DSP: 122113030
HAME: 121859286
 » show all
Reference
PMID:6935192
  Authors
Strickler RC, Tobias B, Covey DF
  Title
Human placental 17 beta-estradiol dehydrogenase and 20 alpha-hydroxysteroid dehydrogenase. Two activities at a single enzyme active site.
  Journal
J Biol Chem 256:316-21 (1981)

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
   KEGG RCLASS (2)   
Gene (12)   
   KEGG GENES (11)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (28)   

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