KEGG ORTHOLOGY: K05424

ORTHOLOGY: K05424

Entry

K05424 KO

Name

LEP

Definition

leptin

Pathway

ko04060

Cytokine-cytokine receptor interaction

ko04080

Neuroactive ligand-receptor interaction

ko04152

AMPK signaling pathway

ko04630

JAK-STAT signaling pathway

ko04920

Adipocytokine signaling pathway

ko04932

Non-alcoholic fatty liver disease

Disease

H02059

Leptin deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05424  LEP; leptin
   04152 AMPK signaling pathway
    K05424  LEP; leptin
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K05424  LEP; leptin
   04060 Cytokine-cytokine receptor interaction
    K05424  LEP; leptin
09150 Organismal Systems
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K05424  LEP; leptin
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K05424  LEP; leptin
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05424  LEP; leptin
Cytokines and growth factors [BR:ko04052]
Cytokines
  CSF and other factors
   K05424  LEP; leptin

Genes

HSA:

3952(LEP)

PTR:	449638(LEP)

PPS:	100983807(LEP)

GGO:	101130896(LEP)

PON:	100440463(LEP)

NLE:	100590604(LEP)

MCC:	698728(LEP)

MCF:	102136844(LEP)

CSAB:

103226854(LEP)

RRO:	104674424(LEP)

RBB:	108544847(LEP)

CJC:	100407456(LEP)

SBQ:	101048464(LEP)

MMU:	16846(Lep)

MCAL:

110296916(Lep)

MPAH:

110317099(Lep)

RNO:	25608(Lep)

MUN:	110562957(Lep)

CGE:	100774160(Lep)

NGI:	103744567(Lep)

HGL:	101722703(Lep)

CCAN:

109698564(Lep)

OCU:	100008747(LEP)

TUP:	102469400(LEP)

CFA:	403616(LEP)

VVP:	112929007(LEP)

AML:	100474605(LEP)

UMR:	103676631(LEP)

UAH:	113263750(LEP)

ORO:	101363785(LEP)

ELK:

111151979

FCA:	493838(LEP)

PTG:	102953663(LEP)

PPAD:

109268944(LEP)

AJU:	106988453(LEP)

BTA:	280836(LEP)

BOM:	102276736(LEP)

BIU:	109557596(LEP)

BBUB:

102401642(LEP)

CHX:	100860794(LEP)

OAS:	443534(LEP)

SSC:	396832(LEP)

CFR:	102504256(LEP)

CDK:	105085360(LEP)

BACU:

103005162(LEP)

LVE:	103081197(LEP)

OOR:	101276663(LEP)

DLE:	111182801(LEP)

PCAD:

102990481 112066353

ECB:	100034042(LEP)

EPZ:	103542787(LEP)

EAI:	106839522(LEP)

MYB:	102242572(LEP) 102258447

MYD:	102759608(LEP)

MNA:	107537334(LEP)

HAI:	109384650(LEP)

DRO:	112299732(LEP)

PALE:

102896937(LEP)

RAY:	107512785(LEP)

MJV:	108395315(LEP)

LAV:	100663871(LEP)

TMU:

101357146

MDO:	100014695(LEP)

SHR:	100930199(LEP)

PCW:	110219143(LEP)

OAA:	100078019(LEP)

TGU:	101233729(LEP)

PHI:

106628856

ETL:

114072465

FPG:	106112855(LEP)

FCH:	106631443(LEP)

ASN:	102369070(LEP)

AMJ:	102576392(LEP)

CMY:

102932266

CPIC:

101947294(LEP)

ACS:	100552163(lep)

PVT:	110084433(LEP)

PBI:	103053032(LEP)

PMUR:

107289214(LEP)

TSR:	106556984(LEP)

PMUA:

114605318(LEP)

GJA:	107111979(LEP)

XLA:	108711253(lep.L) 734226(lep.S)

XTR:	100486715(lep)

NPR:	108787505(LEP)

DRE:	100150233(lepa) 564348(lepb)

CCAR:

IPU:

AMEX:

NCC:

MZE:

ONL:

OLA:	100301595(lep-b)

XMA:

XCO:

PRET:

CVG:

NFU:

KMR:

ALIM:

AOCE:

CSEM:

POV:

LCF:

SDU:

SLAL:

MALB:

SASA:

101448054(lepb1) 101867534(lepb2) 106561227(leptin)

OTW:	112218616 112238037

SALP:

111953061 111961186

SFM:	108918737 108936377

PKI:

111846168

LCM:	102366460(LEP)

RTP:	109930286(lep)

» show all

Reference

PMID:16311215

Authors

Koerner A, Kratzsch J, Kiess W

Title

Adipocytokines: leptin--the classical, resistin--the controversical, adiponectin--the promising, and more to come.

Journal

Best Pract Res Clin Endocrinol Metab 19:525-46 (2005)
DOI:10.1016/j.beem.2005.07.008

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (12)   
   KEGG PATHWAY (12)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (129)   
   KEGG GENES (124)   
   KEGG MGENES (1)   
   RefGene (1)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (145)   

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