KEGG   ORTHOLOGY: K05473
Entry
K05473                      KO                                     

Name
TNFSF11, RANKL, CD254
Definition
tumor necrosis factor ligand superfamily member 11
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04064  NF-kappa B signaling pathway
ko04380  Osteoclast differentiation
ko04917  Prolactin signaling pathway
ko04928  Parathyroid hormone synthesis, secretion and action
ko05224  Breast cancer
ko05323  Rheumatoid arthritis
Disease
H00436  Osteopetrosis
H01470  Giant cell tumor of bone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04928 Parathyroid hormone synthesis, secretion and action
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 09160 Human Diseases
  09162 Cancer: specific types
   05224 Breast cancer
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
  09163 Immune disease
   05323 Rheumatoid arthritis
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
   04090 CD molecules
    K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Tumor necrosis fators
   K05473  TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
CD molecules [BR:ko04090]
 Proteins
  K05473  CD254, TNFSF11; tumor necrosis factor (ligand) superfamily, member 11
Other DBs
GO: 0005164
Genes
HSA: 8600(TNFSF11)
PTR: 467353(TNFSF11)
PPS: 100994539(TNFSF11)
GGO: 101131644(TNFSF11)
PON: 100439883(TNFSF11)
NLE: 100599838(TNFSF11)
MCC: 699955(TNFSF11)
MCF: 102137946(TNFSF11)
CSAB: 103214344(TNFSF11)
RRO: 104671084(TNFSF11)
RBB: 108514105(TNFSF11)
CJC: 100401379(TNFSF11)
SBQ: 101051208(TNFSF11)
MMU: 21943(Tnfsf11)
MCAL: 110309649(Tnfsf11)
MPAH: 110325778(Tnfsf11)
RNO: 103689974 117516(Tnfsf11)
MUN: 110562414(Tnfsf11)
CGE: 100768715(Tnfsf11)
NGI: 103751291(Tnfsf11)
HGL: 101696350(Tnfsf11)
CCAN: 109700348(Tnfsf11)
OCU: 100341009(TNFSF11)
TUP: 102487682(TNFSF11)
CFA: 609418(TNFSF11)
VVP: 112928102(TNFSF11)
AML: 100483079(TNFSF11)
UMR: 103677566(TNFSF11)
UAH: 113251369(TNFSF11)
ORO: 101376926(TNFSF11)
ELK: 111147123
FCA: 724036(TNFSF11)
PTG: 102954463(TNFSF11)
PPAD: 109265885(TNFSF11)
AJU: 106971982(TNFSF11)
BTA: 513836(TNFSF11)
BOM: 102267691(TNFSF11)
BIU: 109566677(TNFSF11)
BBUB: 102393260(TNFSF11)
CHX: 102176335(TNFSF11)
OAS: 100037694(TNFSF11)
SSC: 100037976(TNFSF11)
CFR: 102507742(TNFSF11)
CDK: 105089768(TNFSF11)
BACU: 103002678(TNFSF11)
LVE: 103074658(TNFSF11)
OOR: 101284929(TNFSF11)
DLE: 111175123(TNFSF11)
PCAD: 102978976(TNFSF11)
ECB: 100060254(TNFSF11)
EPZ: 103560371(TNFSF11)
EAI: 106847554(TNFSF11)
MYB: 102260756(TNFSF11)
MYD: 102751742(TNFSF11)
MNA: 107531354(TNFSF11)
HAI: 109386844(TNFSF11)
DRO: 112311127(TNFSF11)
PALE: 102896284(TNFSF11)
RAY: 107517455(TNFSF11)
MJV: 108407315(TNFSF11)
LAV: 100663523(TNFSF11)
TMU: 101342165
MDO: 100011641(TNFSF11)
SHR: 105750026(TNFSF11)
PCW: 110201421(TNFSF11)
OAA: 100076541(TNFSF11)
GGA: 428067(TNFSF11)
MGP: 104917524(TNFSF11)
CJO: 107308113(TNFSF11)
NMEL: 110387248(TNFSF11)
APLA: 101803149(TNFSF11)
ACYG: 106035087(TNFSF11)
TGU: 100227247(TNFSF11)
LSR: 110470890(TNFSF11)
SCAN: 103812581(TNFSF11)
GFR: 102038556(TNFSF11)
FAB: 101822088(TNFSF11)
PHI: 102111124(TNFSF11)
PMAJ: 107212828(TNFSF11)
CCAE: 111935210(TNFSF11)
CCW: 104693175(TNFSF11)
ETL: 114059881(TNFSF11)
FPG: 101919009(TNFSF11)
FCH: 102050665(TNFSF11)
CLV: 102098042(TNFSF11)
EGZ: 104132030(TNFSF11)
NNI: 104010922(TNFSF11)
ACUN: 113480179(TNFSF11)
PADL: 103915905(TNFSF11)
AAM: 106489200(TNFSF11)
ASN: 102387902(TNFSF11)
AMJ: 102559854(TNFSF11)
PSS: 102444457(TNFSF11)
CMY: 102947527(TNFSF11)
CPIC: 101936501(TNFSF11)
ACS: 100566737(tnfsf11)
PVT: 110084678(TNFSF11)
PMUR: 107283208(TNFSF11)
PMUA: 114600094(TNFSF11)
GJA: 107123862(TNFSF11)
XLA: 496322(tnfsf11.L) 733333(tnfsf11.S)
XTR: 100038074(tnfsf11)
NPR: 108790250(TNFSF11)
SRX: 107713713 107749039(tnfsf11)
SANH: 107661329(tnfsf11) 107688674
SGH: 107580040
EEE: 113582613
TRU: 101080086
LCO: 104934832
MZE: 101482899(tnfsf11)
ONL: 100690570
XMA: 102231551(tnfsf11)
XCO: 114148628(tnfsf11)
PRET: 103481812(tnfsf11)
CVG: 107101899
NFU: 107389518(tnfsf11)
KMR: 108245125
ALIM: 106511186
AOCE: 111568245
CSEM: 103391567(tnfsf11)
POV: 109642694
HCQ: 109514543(tnfsf11)
BPEC: 110170617(tnfsf11)
MALB: 109971659
SFM: 108920497(tnfsf11) 108928984
LCM: 102363811(TNFSF11)
SPU: 115922601
 » show all
Reference
PMID:9367155
  Authors
Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, Teepe MC, DuBose RF, Cosman D, Galibert L
  Title
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.
  Journal
Nature 390:175-9 (1997)
DOI:10.1038/36593
  Sequence
[hsa:8600]

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