KEGG   ORTHOLOGY: K05630Help
Entry
K05630                      KO                                     

Name
WWP2, AIP2
Definition
NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
Pathway
ko04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K05630  WWP2, AIP2; NEDD4-like E3 ubiquitin-protein ligase WWP2
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     K05630  WWP2, AIP2; NEDD4-like E3 ubiquitin-protein ligase WWP2
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K05630  WWP2, AIP2; NEDD4-like E3 ubiquitin-protein ligase WWP2
BRITE hierarchy
Genes
HSA: 11060(WWP2)
PTR: 743862(WWP2)
PPS: 100973972(WWP2)
GGO: 101153826(WWP2)
PON: 100438429(WWP2)
NLE: 100604312(WWP2)
MCC: 705464(WWP2)
MCF: 102123009(WWP2)
CSAB: 103233208(WWP2)
RRO: 104655882(WWP2)
RBB: 108514535(WWP2)
CJC: 100405825(WWP2)
SBQ: 101036695(WWP2)
MMU: 66894(Wwp2)
RNO: 291999(Wwp2)
CGE: 100761484(Wwp2)
NGI: 103734667(Wwp2)
HGL: 101710527(Wwp2)
CCAN: 109687553(Wwp2) 109697204
OCU: 100344222(WWP2)
TUP: 102494947(WWP2)
CFA: 479672(WWP2)
AML: 100474146(WWP2)
UMR: 103673607(WWP2)
ORO: 101367994(WWP2)
FCA: 101098349(WWP2)
PTG: 102956978(WWP2)
AJU: 106972155(WWP2)
BTA: 512457(WWP2)
BOM: 102280579(WWP2)
PHD: 102319024 102334677(WWP2)
CHX: 102174504(WWP2)
OAS: 101122376(WWP2)
SSC: 100626361(WWP2)
CFR: 102513891(WWP2)
CDK: 105088391(WWP2)
BACU: 103005821(WWP2)
LVE: 103068585(WWP2)
OOR: 101271187(WWP2)
ECB: 100067291(WWP2)
EPZ: 103549829(WWP2)
EAI: 106842137(WWP2)
MYB: 102263170(WWP2)
MYD: 102764062(WWP2)
HAI: 109389168(WWP2)
RSS: 109461077(WWP2)
PALE: 102889650(WWP2)
LAV: 100662968(WWP2)
TMU: 101351173
MDO: 100020484(WWP2)
SHR: 100917130(WWP2)
OAA: 100077057(WWP2)
GGA: 415868(WWP2)
MGP: 100543013
CJO: 107319450(WWP2)
APLA: 101801353(WWP2)
ACYG: 106046602(WWP2)
TGU: 100230386(WWP2)
GFR: 102041977(WWP2)
FAB: 101820426(WWP2)
PHI: 102113277(WWP2)
PMAJ: 107209932(WWP2)
FPG: 101912384(WWP2)
FCH: 102057100 102057159(WWP2)
CLV: 102094230(WWP2)
EGZ: 104129697(WWP2)
AAM: 106498549(WWP2)
ASN: 102371401(WWP2)
AMJ: 102562530(WWP2)
PSS: 102453914
CMY: 102930866(WWP2)
CPIC: 101946817(WWP2)
ACS: 100561726(wwp2)
PVT: 110076252(WWP2)
PBI: 103053726(WWP2)
GJA: 107106534(WWP2)
XTR: 100038252(wwp2)
NPR: 108790643
DRE: 564527(wwp2)
SANH: 107667683(wwp2) 107695956
CCAR: 109050806
IPU: 108268586
AMEX: 103032112(wwp2)
TRU: 101068381(wwp2)
LCO: 104933815(wwp2)
MZE: 101472498(wwp2)
OLA: 101168206(wwp2)
XMA: 102222753(wwp2)
PRET: 103466297(wwp2)
NFU: 107389275(wwp2)
CSEM: 103379686(wwp2)
BPEC: 110169155
SASA: 106560906(WWP2) 106573662(WWP2)
ELS: 105018552(wwp2)
SFM: 108926616(wwp2)
LCM: 102355333(WWP2)
CMK: 103175970(wwp2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chen A, Gao B, Zhang J, McEwen T, Ye SQ, Zhang D, Fang D
  Title
The HECT-type E3 ubiquitin ligase AIP2 inhibits activation-induced T-cell death by catalyzing EGR2 ubiquitination.
  Journal
Mol Cell Biol 29:5348-56 (2009)
DOI:10.1128/MCB.00407-09
  Sequence
[hsa:11060] [mmu:66894]
Reference
  Authors
Xu H, Wang W, Li C, Yu H, Yang A, Wang B, Jin Y
  Title
WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells.
  Journal
Cell Res 19:561-73 (2009)
DOI:10.1038/cr.2009.31
  Sequence
[hsa:11060]

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