KEGG   ORTHOLOGY: K05633
Entry
K05633                      KO                                     

Name
WWP1, AIP5
Definition
NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
Pathway
ko04120  Ubiquitin mediated proteolysis
ko04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
   04121 Ubiquitin system
    K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K05633  WWP1, AIP5; NEDD4-like E3 ubiquitin-protein ligase WWP1
Genes
HSA: 11059(WWP1)
PTR: 464269(WWP1)
PPS: 100990521(WWP1)
GGO: 101148212(WWP1)
PON: 100442298(WWP1)
NLE: 100580729(WWP1)
MCC: 694098(WWP1)
MCF: 101865249(WWP1)
CSAB: 103237079(WWP1)
CATY: 105572885(WWP1)
RRO: 104674278(WWP1)
RBB: 108531641(WWP1)
TFN: 117079140(WWP1) 117083614
CJC: 100400473(WWP1)
SBQ: 101053807(WWP1)
MMUR: 105876567(WWP1)
MMU: 107568(Wwp1)
MCAL: 110292851(Wwp1)
MPAH: 110338628(Wwp1)
RNO: 297930(Wwp1)
MCOC: 116088033(Wwp1)
MUN: 110565189(Wwp1)
CGE: 100757929(Wwp1)
PLEU: 114704115(Wwp1)
NGI: 103731153(Wwp1)
HGL: 101725489(Wwp1)
CCAN: 109696210(Wwp1)
OCU: 100350478(WWP1)
TUP: 102483029(WWP1)
CFA: 100856769(WWP1)
VVP: 112930774(WWP1)
VLG: 121498535(WWP1)
AML: 100475461(WWP1)
UMR: 103661400(WWP1)
UAH: 113252973(WWP1)
ORO: 101374742(WWP1)
ELK: 111146529
MPUF: 101682164(WWP1)
EJU: 114216475(WWP1)
FCA: 101095882(WWP1)
PTG: 102969670(WWP1)
PPAD: 109269443(WWP1)
AJU: 106977247(WWP1)
HHV: 120225202(WWP1)
BTA: 513789(WWP1)
BOM: 102271307(WWP1)
BBUB: 102404172(WWP1)
CHX: 102171442(WWP1)
OAS: 101117426(WWP1) 101122347
ODA: 120878521(WWP1)
SSC: 100157283(WWP1)
CFR: 102509478(WWP1)
CDK: 105088497(WWP1)
BACU: 103009404(WWP1)
LVE: 103076297(WWP1)
OOR: 101288239(WWP1)
DLE: 111164981(WWP1)
PCAD: 102990840(WWP1)
ECB: 100055725(WWP1)
EPZ: 103541679(WWP1)
EAI: 106829847(WWP1)
MYB: 102261539(WWP1)
MYD: 102764292(WWP1)
MMYO: 118670456(WWP1)
MNA: 107526470(WWP1)
HAI: 109387583(WWP1)
DRO: 112320867(WWP1)
SHON: 118989867(WWP1)
AJM: 119046362(WWP1)
MMF: 118631398(WWP1)
PALE: 102896487(WWP1)
RAY: 107514922(WWP1)
MJV: 108406620(WWP1)
LAV: 100662373(WWP1)
TMU: 101348915
MDO: 100029107(WWP1)
SHR: 100919125(WWP1)
PCW: 110196723(WWP1)
OAA: 100075459(WWP1)
GGA: 420212(WWP1)
PCOC: 116227584(WWP1)
CJO: 107310303(WWP1)
NMEL: 110394777(WWP1)
APLA: 101801705(WWP1)
ACYG: 106030549(WWP1)
TGU: 100219204(WWP1)
LSR: 110477418(WWP1)
SCAN: 103813369(WWP1)
PMOA: 120495768(WWP1)
GFR: 102038961(WWP1)
FAB: 101818641(WWP1)
PHI: 102101936(WWP1)
PMAJ: 107199517(WWP1)
CCAE: 111924578(WWP1)
CCW: 104692771(WWP1)
ETL: 114065895(WWP1)
FPG: 101914676(WWP1)
FCH: 102050477(WWP1)
CLV: 102084568(WWP1)
EGZ: 104123325(WWP1)
NNI: 104022786(WWP1)
ACUN: 113476997(WWP1)
PADL: 103924064(WWP1)
AAM: 106496263(WWP1)
ASN: 102377089(WWP1)
AMJ: 102576998(WWP1)
CPOO: 109320063(WWP1)
GGN: 109305007(WWP1)
PSS: 102448686(WWP1)
CMY: 102941009(WWP1)
CPIC: 101937468(WWP1)
TST: 117873633(WWP1)
CABI: 116828260(WWP1)
ACS: 100558141(wwp1)
PVT: 110085122(WWP1)
PBI: 103062713(WWP1)
PMUR: 107284961(WWP1)
TSR: 106551170(WWP1)
PGUT: 117668474(WWP1)
PMUA: 114600452(WWP1)
ZVI: 118089829(WWP1)
GJA: 107119005(WWP1)
XLA: 108695372(wwp1.S) 108719322(wwp1.L)
XTR: 100038255(wwp1)
NPR: 108786471(WWP1)
DRE: 103909792
SGH: 107572619(wwp1) 107573294
CAUA: 113042666 113068786(wwp1)
IPU: 108272149(wwp1)
PHYP: 113545425(wwp1)
AMEX: 103040182(wwp1)
EEE: 113579398(wwp1)
LCO: 104924707
NCC: 104951727(wwp1)
ELY: 117264618
PLEP: 121960869
SLUC: 116055719
GAT: 120811614
MSAM: 119906884
MZE: 101467964(wwp1)
ONL: 100701023
OAU: 116311299
OLA: 101169496(wwp1)
OML: 112151160
XMA: 102223052(wwp1)
XCO: 114136982(wwp1)
XHE: 116711598(wwp1)
PRET: 103482265(wwp1)
NFU: 107382627(wwp1)
KMR: 108248254
ALIM: 106533496(wwp1)
AOCE: 111565192(wwp1)
CSEM: 103377056(wwp1)
POV: 109629755(wwp1)
LCF: 108898298
SDU: 111228237(wwp1)
SLAL: 111659839(wwp1)
XGL: 120789816
HCQ: 109507829(wwp1)
BPEC: 110158668(wwp1)
MALB: 109965105(wwp1)
SASA: 106578528(wwp1)
OTW: 112215571(wwp1)
OMY: 110535527
SALP: 111973057(wwp1)
ELS: 105031534(wwp1)
LOC: 102695344(wwp1)
LCM: 102360416(WWP1)
CMK: 103185090(wwp1)
RTP: 109914200
BFO: 118417956
CIN: 100182617
SCLV: 120332141
SPU: 752270
APLC: 110987831
DME: Dmel_CG4244(Su(dx))
DER: 6542319
DSE: 6617446
DSI: Dsimw501_GD23128(Dsim_GD23128)
DAN: 6497419
DSR: 110182268
DPE: 6595647
DMN: 108163243
DWI: 6642501
DAZ: 108611157
DNV: 108649950
DHE: 111594789
DVI: 6628204
MDE: 101895204
LCQ: 111680785
ACOZ: 120959804
AARA: 120903165
AAG: 5569077
AALB: 109421660
AME: 100576472
BIM: 100750215
BTER: 100642510
CCAL: 108622392
OBB: 114874507
MGEN: 117220288
NMEA: 116432901
SOC: 105194006
MPHA: 105834703
AEC: 105147293
ACEP: 105624290
PBAR: 105428752
VEM: 105569518
HST: 105192168
DQU: 106741361
CFO: 105259285
FEX: 115234955
LHU: 105673973
PGC: 109852084
OBO: 105278295
PCF: 106790327
NVI: 100119610
CSOL: 105364765
MDL: 103578483
TCA: 662990
DPA: 109538604
ATD: 109597227
AGB: 108915839
NVL: 108569397
APLN: 108736596
PPYR: 116172734
OTU: 111415453
BMOR: 101741308
BMAN: 114250949
MSEX: 115441025
PMAC: 106710825
PPOT: 106099454
PXU: 106127577
PRAP: 110998666
ZCE: 119834032
HAW: 110375445
TNL: 113501562
PXY: 105388335
API: 100159135
DNX: 107169827
AGS: 114132997
RMD: 113559639
BTAB: 109040962
DCI: 103512873
CLEC: 106668797
NLU: 111049833
ZNE: 110839720
CSEC: 111861327
FCD: 110842235
PVM: 113824435
EAF: 111707930
DSV: 119466438
RSAN: 119376571
RMP: 119176456
VDE: 111252898
VJA: 111270609
TUT: 107363097
DPTE: 113791124
CSCU: 111623400
PTEP: 107442990
SDM: 118202137
CEL: CELE_Y65B4BR.4(wwp-1)
CBR: CBG05115(Cbr-wwp-1)
BMY: BM_BM6975(Bma-wwp-1)
PCAN: 112576975
BGT: 106068453
GAE: 121388340
CRG: 105343449
MYI: 110466815
PMAX: 117337496
OBI: 106883192
LAK: 106151787
EGL: EGR_05702
NVE: 5521489
EPA: 110245349
ATEN: 116289519
AMIL: 114966510
PDAM: 113664694
SPIS: 111342935
DGT: 114516894
AQU: 100636847
 » show all
Reference
  Authors
Chen CS, Bellier A, Kao CY, Yang YL, Chen HD, Los FC, Aroian RV
  Title
WWP-1 is a novel modulator of the DAF-2 insulin-like signaling network involved in pore-forming toxin cellular defenses in Caenorhabditis elegans.
  Journal
PLoS One 5:e9494 (2010)
DOI:10.1371/journal.pone.0009494
  Sequence
Reference
  Authors
Komuro A, Imamura T, Saitoh M, Yoshida Y, Yamori T, Miyazono K, Miyazawa K
  Title
Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).
  Journal
Oncogene 23:6914-23 (2004)
DOI:10.1038/sj.onc.1207885
  Sequence
[hsa:11059]

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