KEGG   ORTHOLOGY: K05634
Entry
K05634                      KO                                     

Name
PRNP, PrP, CD230
Definition
prion protein
Pathway
ko04216  Ferroptosis
ko05020  Prion disease
ko05022  Pathways of neurodegeneration - multiple diseases
Disease
H00061  Prion disease
H01243  Huntington disease-like syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K05634  PRNP, PrP, CD230; prion protein
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    K05634  PRNP, PrP, CD230; prion protein
   05022 Pathways of neurodegeneration - multiple diseases
    K05634  PRNP, PrP, CD230; prion protein
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K05634  PRNP, PrP, CD230; prion protein
   04090 CD molecules
    K05634  PRNP, PrP, CD230; prion protein
   00536 Glycosaminoglycan binding proteins
    K05634  PRNP, PrP, CD230; prion protein
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K05634  PRNP, PrP, CD230; prion protein
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K05634  PRNP, PrP, CD230; prion protein
CD molecules [BR:ko04090]
 Proteins
  K05634  CD230, PRNP; prion protein
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Others
   K05634  PRNP, PrP, CD230; prion protein
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
 Others
  K05634  PRNP, PrP, CD230; prion protein
Genes
HSA: 5621(PRNP)
PTR: 458076(PRNP)
PPS: 100984581(PRNP)
GGO: 101135304(PRNP)
PON: 100173712(PRNP)
NLE: 100587690(PRNP)
MCC: 717859(PRNP)
MCF: 102127229(PRNP)
CSAB: 103247014(PRNP)
RRO: 104674584(PRNP)
RBB: 108533419(PRNP)
CJC: 100398566(PRNP)
SBQ: 101039770(PRNP)
MMU: 19122(Prnp)
MCAL: 110312291(Prnp)
MPAH: 110318145(Prnp)
RNO: 24686(Prnp)
MUN: 110556990(Prnp)
CGE: 100762792(Prnp)
NGI: 103736406(Prnp)
HGL: 101710391(Prnp)
CCAN: 109699373(Prnp)
OCU: 100008658(PRNP)
TUP: 102478560(PRNP)
CFA: 485783(PRNP)
VVP: 112930073(PRNP)
AML: 100473044(PRNP)
UMR: 103674536(PRNP)
UAH: 113258373(PRNP)
ORO: 101370976(PRNP)
ELK: 111141608
FCA: 101087310(PRNP)
PTG: 102964375(PRNP)
PPAD: 109274743(PRNP)
AJU: 106980154(PRNP)
BTA: 281427(PRNP)
BOM: 102278930(PRNP)
BIU: 109568114(PRNP)
BBUB: 102412748(PRNP)
CHX: 102169975(PRNP)
OAS: 493887(PRNP)
SSC: 494014(PRNP)
CFR: 102518771(PRNP)
CDK: 105101461(PRNP)
BACU: 103021028(PRNP)
LVE: 103078120(PRNP)
OOR: 101286552(PRNP)
DLE: 111165622(PRNP)
PCAD: 102990340(PRNP)
ECB: 100065904(PRNP)
EPZ: 103550738(PRNP)
EAI: 106847681(PRNP)
MYB: 102247570(PRNP)
MYD: 102769375(PRNP)
MNA: 107536389(PRNP)
HAI: 109383849(PRNP)
DRO: 112304028(PRNP)
PALE: 102891407(PRNP)
RAY: 107505150(PRNP)
MJV: 108399245(PRNP)
LAV: 100671000(PRNP)
TMU: 101348533
MDO: 554189(PRNP)
SHR: 100927381(PRNP)
PCW: 110207628(PRNP)
OAA: 100086593
GGA: 396452(PRNP)
MGP: 100538706(PRNP)
CJO: 107323677(PRNP)
NMEL: 110387172(PRNP)
ACYG: 106047656(PRNP)
TGU: 115498155(PRNP)
LSR: 110480188(PRNP)
SCAN: 103822732(PRNP)
FAB: 101814306(PRNP)
PHI: 102101927(PRNP)
PMAJ: 107213897(PRNP)
CCW: 120411164
ETL: 114070395(PRNP)
FPG: 101921898(PRNP)
FCH: 102055080(PRNP)
CLV: 102088986(PRNP)
EGZ: 104130355(PRNP)
ACUN: 113488134(PRNP)
ASN: 102374683(PRNP)
AMJ: 102561492(PRNP)
PSS: 102460857(PRNP)
CMY: 102943321
CPIC: 101932649(PRNP)
ACS: 100555750
PBI: 103064789(PRNP)
PMUR: 107299295
TSR: 106543634(PRNP)
PMUA: 114585408
GJA: 107108354(PRNP)
XLA: 398272(prnp.L) 444620(prnp.S)
XTR: 100158502(prnp)
NPR: 108797150(PRNP)
LCM: 102348289(PRNP)
 » show all
Reference
PMID:3755672
  Authors
Kretzschmar HA, Stowring LE, Westaway D, Stubblebine WH, Prusiner SB, Dearmond SJ
  Title
Molecular cloning of a human prion protein cDNA.
  Journal
DNA 5:315-24 (1986)
DOI:10.1089/dna.1986.5.315
  Sequence
[hsa:5621]
Reference
  Authors
Mani K, Cheng F, Havsmark B, Jonsson M, Belting M, Fransson LA
  Title
Prion, amyloid beta-derived Cu(II) ions, or free Zn(II) ions support S-nitroso-dependent autocleavage of glypican-1 heparan sulfate.
  Journal
J Biol Chem 278:38956-65 (2003)
DOI:10.1074/jbc.M300394200
  Sequence
[hsa:5621] [mmu:19122]

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