KEGG   ORTHOLOGY: K05641
Entry
K05641                      KO                                     
Symbol
ABCA1
Name
ATP-binding cassette, subfamily A (ABC1), member 1
Pathway
map02010  ABC transporters
map04148  Efferocytosis
map04975  Fat digestion and absorption
map04979  Cholesterol metabolism
map05417  Lipid and atherosclerosis
Disease
H00159  Tangier disease
H00930  Hypoalphalipoproteinemia
H02505  Atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
   04979 Cholesterol metabolism
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  ABCA (ABC1) subfamily
   ABCA1, 2, 3, 4, 7, 12, 13 subgroups
    K05641  ABCA1; ATP-binding cassette, subfamily A (ABC1), member 1
Other DBs
TC: 3.A.1.211
Genes
HSA: 19(ABCA1)
PTR: 464630(ABCA1)
PPS: 100971870(ABCA1)
GGO: 101151472(ABCA1)
PON: 100441342(ABCA1)
PPYG: 129043743(ABCA1)
NLE: 100606619(ABCA1)
HMH: 116475500(ABCA1)
SSYN: 129479070(ABCA1)
MCC: 716146(ABCA1)
MCF: 102117645(ABCA1)
MTHB: 126937939
MNI: 105481013(ABCA1)
CSAB: 103219077(ABCA1)
CATY: 105600323(ABCA1)
PANU: 100997056(ABCA1)
TGE: 112607819(ABCA1)
MLEU: 105529293(ABCA1)
RRO: 104654215(ABCA1)
RBB: 108532571(ABCA1)
TFN: 117098885(ABCA1)
PTEH: 111536142(ABCA1)
CANG: 105516145(ABCA1)
CJC: 100403133(ABCA1)
SBQ: 101046397(ABCA1)
CIMI: 108303831(ABCA1)
ANAN: 105707937(ABCA1)
CSYR: 103276045(ABCA1)
MMUR: 105855724(ABCA1)
LCAT: 123646642(ABCA1)
PCOQ: 105805614(ABCA1)
OGA: 100964745(ABCA1)
MMU: 11303(Abca1)
MCAL: 110292559(Abca1)
MPAH: 110323695(Abca1)
RNO: 313210(Abca1)
MCOC: 116096020(Abca1)
ANU: 117708490(Abca1)
MUN: 110565774(Abca1)
CGE: 100761226(Abca1)
MAUA: 101838333(Abca1)
PROB: 127224699(Abca1)
PLEU: 114683448(Abca1)
MORG: 121451264(Abca1)
MFOT: 126515248
AAMP: 119826167(Abca1)
NGI: 103748921(Abca1)
HGL: 101704546(Abca1)
CPOC: 100720792(Abca1)
CCAN: 109691834(Abca1)
DORD: 105990807(Abca1)
DSP: 122123988(Abca1)
PLOP: 125346139(Abca1)
NCAR: 124964198
MMMA: 107147730(Abca1)
OCU: 100356765
OPI: 101516816(ABCA1)
TUP: 102489626(ABCA1)
GVR: 103603356(ABCA1)
CFA: 481651(ABCA1)
CLUD: 112650438(ABCA1)
VVP: 112922973(ABCA1)
VLG: 121495748(ABCA1)
NPO: 129494709(ABCA1)
AML: 100483394(ABCA1)
UMR: 103678544(ABCA1)
UAR: 123781247(ABCA1)
ELK: 111145612
LLV: 125083984
MPUF: 101679430(ABCA1)
MNP: 132024543(ABCA1)
MLK: 131813118(ABCA1)
NVS: 122917384(ABCA1)
ORO: 101382837(ABCA1)
EJU: 114213494(ABCA1)
ZCA: 113934154(ABCA1)
MLX: 118017859(ABCA1)
NSU: 110581396
LWW: 102740136
FCA: 101083885(ABCA1)
PYU: 121034775
PCOO: 112869448(ABCA1)
PBG: 122474526(ABCA1)
PVIV: 125150029(ABCA1)
LRUF: 124502632
PTG: 102960483(ABCA1)
PPAD: 109270041(ABCA1)
PUC: 125926245
AJU: 106979364
HHV: 120236994(ABCA1)
BTA: 535379(ABCA1)
BOM: 102280059(ABCA1)
BIU: 109563312(ABCA1)
BBUB: 102400056(ABCA1)
BBIS: 104991148(ABCA1)
CHX: 102179197(ABCA1)
OAS: 101119015(ABCA1)
BTAX: 128052437 128052450(ABCA1)
ODA: 120864128(ABCA1)
CCAD: 122431656(ABCA1)
SSC: 100152112(ABCA1)
CFR: 102509338(ABCA1)
CBAI: 105067419(ABCA1)
CDK: 105087915(ABCA1)
VPC: 102536620(ABCA1)
BACU: 103004596(ABCA1)
BMUS: 118896875(ABCA1)
LVE: 103070957(ABCA1)
OOR: 101273707(ABCA1)
DLE: 111188018(ABCA1)
PCAD: 102979910(ABCA1)
PSIU: 116755343(ABCA1)
NASI: 112405299(ABCA1)
ECB: 100054241(ABCA1)
EPZ: 103555518(ABCA1)
EAI: 106830496(ABCA1)
MYB: 102244473(ABCA1)
MYD: 102769534(ABCA1)
MMYO: 118667229(ABCA1)
MLF: 102428362(ABCA1)
MDT: 132212230(ABCA1)
PKL: 118716232(ABCA1)
EFUS: 103286372(ABCA1)
MNA: 107546564(ABCA1)
DRO: 112304621(ABCA1)
SHON: 118979609(ABCA1)
AJM: 119034850(ABCA1)
PDIC: 114491332(ABCA1)
PHAS: 123819577(ABCA1)
MMF: 118629930(ABCA1)
PPAM: 129079377(ABCA1)
HAI: 109371278(ABCA1)
RFQ: 117031810(ABCA1)
PALE: 102885306(ABCA1)
PGIG: 120608703(ABCA1)
PVP: 105295342(ABCA1)
RAY: 107516398(ABCA1)
MJV: 108409431(ABCA1)
TOD: 119232987(ABCA1)
SARA: 101543604(ABCA1)
SETR: 126004506(ABCA1)
LAV: 100666529(ABCA1)
TMU: 101352346
ETF: 101643958(ABCA1)
DNM: 101417886(ABCA1)
MDO: 100013781(ABCA1)
GAS: 123248973(ABCA1)
SHR: 100921930(ABCA1)
AFZ: 127541818
PCW: 110214477(ABCA1)
TVP: 118831736(ABCA1)
OAA: 100075984(ABCA1)
GGA: 373945(ABCA1) 770610(ABCA7)
PCOC: 116235807(ABCA7) 116238178(ABCA1)
MGP: 100542147(ABCA7) 100545145(ABCA1)
CJO: 107306430(ABCA1) 107325421(ABCA7)
TPAI: 128072040(ABCA7) 128089211(ABCA1)
LMUT: 125685064(ABCA7) 125686713(ABCA1)
NMEL: 110388803(ABCA7) 110389287(ABCA1)
APLA: 101796019(ABCA1) 113845670(ABCA7)
ACYG: 106040434(ABCA1) 106048214(ABCA7)
CATA: 118260055(ABCA7) 118260089(ABCA1)
AFUL: 116499079(ABCA7) 116500367(ABCA1)
TGU: 100220408(ABCA7) 100220820(ABCA1)
LSR: 110472799(ABCA1) 110475771(ABCA7)
SCAN: 103821238(ABCA1) 103822044(ABCA7)
PMOA: 120495881(ABCA7) 120509438(ABCA1)
OTC: 121337404(ABCA1) 121342328(ABCA7)
PRUF: 121355319(ABCA1) 121361621(ABCA7)
GFR: 102037171(ABCA7) 102041458(ABCA1)
FAB: 101807730(ABCA1) 101817174(ABCA7)
OMA: 130264337(ABCA7) 130265528(ABCA1)
PHI: 102112452(ABCA1) 102113780(ABCA7)
PMAJ: 107215571(ABCA7) 107216038(ABCA1)
CCAE: 111941779
CCW: 104689733(ABCA1) 104697058(ABCA7)
CBRC: 103619199(ABCA1) 103622180(ABCA7)
ETL: 114063104(ABCA1) 114066412(ABCA7)
ZAB: 102065315 102073466(ABCA1)
ZLE: 135458863(ABCA7) 135459310(ABCA1)
ACHL: 103812191(ABCA1)
SVG: 106856781(ABCA1) 106857049(ABCA7)
MMEA: 130580228(ABCA7) 130584925(ABCA1)
HRT: 120763354(ABCA7) 120765074(ABCA1)
SATI: 136371920(ABCA7) 136373758(ABCA1)
FPG: 101912854(ABCA7) 101913242(ABCA1)
FCH: 102047305(ABCA7) 102056980(ABCA1)
CCRI: 104164017
NNT: 104406982(ABCA1)
SHAB: 115601086(ABCA1) 115618018(ABCA7)
ACUN: 113490020(ABCA1)
TALA: 104363706(ABCA1) 116961656(ABCA7)
ACHC: 115336503(ABCA1) 115349417(ABCA7)
HALD: 104325345(ABCA1)
HLE: 104829162(ABCA7) 104830367(ABCA1)
CSTI: 104554333(ABCA1)
LDI: 104353274(ABCA1)
MNB: 103781919(ABCA1)
DPUB: 104300557(ABCA7) 104305773(ABCA1)
AVIT: 104278423(ABCA1)
BRHI: 104495113(ABCA1)
EGZ: 104123362(ABCA1) 104127389(TMEM259)
NNI: 104011942(ABCA1) 104016304(ABCA7)
PCRI: 104036546(ABCA1)
PCAO: 104042203(ABCA1)
PADL: 103925589(ABCA1)
AFOR: 103899418(ABCA7) 103904745(ABCA1)
FGA: 104073687
GSTE: 104257150(ABCA1)
CLV: 102096351(ABCA1)
MUI: 104538664(ABCA1)
PGUU: 104463807
PLET: 104625707(ABCA1)
EHS: 104507713
CMAC: 104482154(ABCA1)
CUCA: 104062628(ABCA1) 104065780(ABCA7)
TEO: 104383375(ABCA1)
BREG: 104643307(ABCA1)
OHA: 104330147(ABCA1)
ACAR: 104530827(ABCA1)
CPEA: 104389216(ABCA1)
CVF: 104288405(ABCA1)
RTD: 128900576(ABCA7) 128902493(ABCA1)
AAM: 106482494(ABCA1) 106483819
AROW: 112965609(ABCA7) 112972308(ABCA1)
NPD: 112946820(ABCA7) 112956409(ABCA1)
TGT: 104572789(ABCA1)
DNE: 112982179(ABCA1) 112988093(ABCA7)
SCAM: 104145395 104152276(ABCA1)
ASN: 102384149(ABCA1) 102387412(ABCA7)
AMJ: 102571038(ABCA7) 102572232(ABCA1)
CPOO: 109312396(ABCA7) 109323437(ABCA1)
GGN: 109294707(ABCA7) 109297382(ABCA1)
PSS: 102456667(ABCA1)
CMY: 102929738(ABCA7) 102937788(ABCA1)
CCAY: 125627310(ABCA7) 125637056(ABCA1)
DCC: 119848292(ABCA7) 119855660(ABCA1)
CPIC: 101946886(ABCA7) 101953849(ABCA1)
TST: 117868945(ABCA7) 117878699(ABCA1)
CABI: 116820644(ABCA1) 116828036(ABCA7)
MRV: 120391651(ABCA7) 120407992(ABCA1)
ACS: 100557081(abca1)
ASAO: 132768074(ABCA1) 132781163
PVT: 110083188(ABCA1) 110090586
SUND: 121923340(ABCA1) 121937012
PBI: 103054084(ABCA1)
PMUR: 107286307(ABCA1)
CTIG: 120311453(ABCA1)
TSR: 106544862
PGUT: 117661626(ABCA1)
APRI: 131193169(ABCA1)
PTEX: 113448022(ABCA1)
NSS: 113420592(ABCA1)
VKO: 123030168(ABCA1) 123035370
PMUA: 114587887(ABCA1) 114588678
PRAF: 128405158(ABCA1) 128405866(ABCA7)
ZVI: 118075295(ABCA1) 118086011(ABCA7)
HCG: 128348105(ABCA1) 128348277(ABCA7)
GJA: 107113264(ABCA1) 107121240
STOW: 125433286(ABCA7) 125436299(ABCA1)
EMC: 129329880(ABCA7) 129334339(ABCA1)
XLA: 108695393(abca1.L) 108706934(abca1.S)
XTR: 100491942(abca1)
NPR: 108794435(ABCA1)
RTEM: 120945316(ABCA1)
BBUF: 120989240(ABCA1)
BGAR: 122943763
MUO: 115462091 115463631(ABCA1)
GSH: 117345793 117347437(ABCA1)
DRE: 100136868(abca1b) 558924(abca1a) 561460(abca7)
PTET: 122353135(abca1a) 122354308(abca7) 122357778(abca1b) 122358224
LROH: 127173411 127175873(abca1b) 127178156(abca1a)
OMC: 131545595(abca1a) 131549343(abca7) 131553743(abca1b)
PPRM: 120460992(abca1b) 120467738(abca7) 120477781 120488784(abca1a)
RKG: 130069126(abca7) 130072518(abca1b) 130082375(abca1a)
MAMB: 125256828(abca7) 125259439(abca1b) 125265746 125271865(abca1a)
CERY: 137021730(abca7) 137023299(abca1b) 137031851(abca1a)
TROS: 130552732(abca1a) 130563554(abca1b) 130570970(abca7)
TDW: 130410749(abca7) 130413878(abca1a) 130437606(abca1b)
MANU: 129422821(abca1b) 129427242(abca7) 129444057(abca1a)
IPU: 108260577 108260597(abca1a) 108271263(abca7) 108275029(abca1b)
IFU: 128603974(abca1a) 128604269 128613401(abca7) 128617907(abca1b)
SMEO: 124381152(abca1a) 124381467 124390866(abca7) 124391901(abca1b)
TFD: 113635483 113641416(abca1a) 113657690(abca7) 113659876(abca1b)
TVC: 132841636(abca1a) 132841765 132851309(abca7) 132856894(abca1b)
TRN: 134309360(abca1b) 134326054(abca1a) 134326904 134331737(abca7)
AMEX: 103028164(abca1a) 103039328(abca7) 103041974 103044029(abca1b)
CMAO: 118804202(abca1a) 118811517(abca1b) 118818840(zgc:172302)
CHAR: 105888624(abca1b) 105903072 122129100(abca7) 122129828(abca1a)
TFS: 130522705 130526937 130528358(abca7) 130531435(abca1b)
NCC: 104958945(abca1) 104962031(abca7)
PGEO: 117440016 117445133(zgc:172302) 117463484
GACU: 117544259(zgc:172302) 117559274 117561276
ELY: 117246311 117253983(zgc:172302) 117255906 117259820(abca1b)
EFO: 125883941 125885909 125894365(abca1b) 125895657(abca7)
ECRA: 117934569 117936722 117950885(zgc:172302)
GAT: 120817300(abca1b) 120822748 120823593(abca7) 120824562
PPUG: 119211440(abca1b) 119216535(zgc:172302) 119218439 119222665
AFB: 129089794(abca1b) 129093563 129094902(abca7) 129096247
MSAM: 119888329(abca1b) 119899363 119900515(abca7) 119911855
SCHU: 122870371 122874137 122878143(abca7) 122880511(abca1b)
CUD: 121504174 121508842 121512157(abca7) 121516223(abca1b)
ALAT: 119007280(abca1b) 119027099 119028482(zgc:172302) 119032235
OAU: 116313301 116316888(abca7) 116332055(abca1b) 116333175
OML: 112140337 112150479(zgc:172302) 112153262(abca1b) 112156111
GAF: 122820345 122829792 122836776(abca1b) 122839091(abca7)
CTUL: 119784578(abca1b) 119787056 119798788(abca7)
GMU: 124860377(abca1b) 124868167 124874383(abca7) 124880928
KMR: 108234389(zgc:172302) 108234870 108241480 108248967(abca1b)
NWH: 119407681(abca7) 119408377(abca1b) 119422387 119426037
HHIP: 117751749 117760445(zgc:172302) 117769080(abca1b) 117769461
HSP: 118102796 118112351(abca1b) 118115595 118120801(abca7)
PPLT: 128430356 128437258 128445462(abca1b) 128447610(abca7)
SMAU: 118312226 118317227 118317752(abca7) 118320040(abca1b)
XGL: 120785452(abca1b) 120791087(abca7) 120797184 120799665
BSPL: 114850366 114853524(abca7) 114863520 114864568(abca1b)
SJO: 128362401(abca7) 128363280(abca1b) 128375911 128384387
AANG: 118224515(zgc:172302) 118230978 118231754
LOC: 102683509 102685889(abca7) 102689923(abca1)
PSEX: 120532285(abca1a)
LCM: 102348605(ABCA1) 102348684 102366526(ABCA7)
RTP: 109913748 109936492(abca7)
BFO: 118431360
BBEL: 109465451
CIN: 100184707
SCLV: 120335282
LPIC: 129270858
SKO: 102809967
AME: 410829
ACER: 108002803
ALAB: 122719914
ADR: 102673872
AFLR: 100868846
BIM: 100745943
BBIF: 117206493
BVK: 117236721
BVAN: 117155594
BTER: 100650392
BAFF: 126918622
BPYO: 122575877
BPAS: 132907674
FVI: 122531776
OBB: 114872769
OLG: 117600058
NMEA: 116430078
CGLO: 123262254
FAS: 105269888
VCAN: 122419466
AROA: 105692916
CCRN: 123298074
NLU: 111044570
HVI: 124364405
SGRE: 126336982
BROR: 134539137
IEL: 124157355
FCD: 110847107
DPZ: 124348825
PVM: 113801922
PJA: 122254047
HAME: 121868674
LSM: 121119214
PPOI: 119107019
VJA: 111268804
TUT: 107368118
CSCU: 111637538
CVS: 136969865
PTEP: 107448522
UDV: 129228236
SDM: 118197423
PMEO: 129581832
CEL: CELE_F12B6.1(abt-2)
CBR: CBG_03891(Cbr-abt-2)
BMY: BM_BM3319(Bma-abt-2)
PVUL: 126819203
PCAN: 112573706
BGT: 106070643
GAE: 121374869
HRF: 124136169
MCAF: 127738780
MMER: 123524209
RPHI: 132720177
OBI: 106884520
OSN: 115214536
LJP: 135471871
LAK: 106176500
EGL: EGR_07314
LLON: 135486970
NVE: 5519087
EPA: 110245024
AMIL: 114956043
PDAM: 113673233
SPIS: 111341520
XEN: 124445090
HMG: 100214482
AQU: 100642126
 » show all
Reference
  Authors
Oram JF, Vaughan AM
  Title
ABCA1-mediated transport of cellular cholesterol and phospholipids to HDL apolipoproteins.
  Journal
Curr Opin Lipidol 11:253-60 (2000)
DOI:10.1097/00041433-200006000-00005
Reference
  Authors
Langmann T, Klucken J, Reil M, Liebisch G, Luciani MF, Chimini G, Kaminski WE, Schmitz G
  Title
Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.
  Journal
Biochem Biophys Res Commun 257:29-33 (1999)
DOI:10.1006/bbrc.1999.0406
  Sequence
[hsa:19]

DBGET integrated database retrieval system