KEGG   ORTHOLOGY: K05665Help
Entry
K05665                      KO                                     

Name
ABCC1
Definition
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
Pathway
ko01523  Antifolate resistance
ko02010  ABC transporters
ko04071  Sphingolipid signaling pathway
ko04977  Vitamin digestion and absorption
ko05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
 09150 Organismal Systems
  09154 Digestive system
   04977 Vitamin digestion and absorption
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
 09160 Human Diseases
  09161 Cancers: Overview
   05206 MicroRNAs in cancer
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
  09176 Drug resistance: Antineoplastic
   01523 Antifolate resistance
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
Enzymes [BR:ko01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.3  ABC-type glutathione-S-conjugate transporter
     K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
Transporters [BR:ko02000]
 ABC Transporters, Eukaryotic Type
  ABCC (CFTR/MRP) subfamily
   ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
    K05665  ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1
BRITE hierarchy
Other DBs
COG: COG1132
GO: 0015431
TC: 3.A.1.208.8 3.A.1.208.11
Genes
HSA: 4363(ABCC1)
PTR: 453952(ABCC1)
PPS: 100969990
GGO: 101130854(ABCC1)
PON: 100431822(ABCC1)
NLE: 100588347 100590031 100596072 100600156 100602390(ABCC1)
MCC: 717857(ABCC1)
MCF: 102133648(ABCC1)
CSAB: 103228870(ABCC1)
RRO: 104668218(ABCC1)
RBB: 108529411(ABCC1)
CJC: 100391747(ABCC1) 100414398
SBQ: 101029348(ABCC1)
MMU: 17250(Abcc1)
RNO: 24565(Abcc1)
CGE: 100689208(Abcc1)
NGI: 103731543(Abcc1)
HGL: 101725452(Abcc1)
CCAN: 109697739(Abcc1)
OCU: 100345841(ABCC1)
TUP: 102470104(ABCC1)
CFA: 403453(ABCC1)
AML: 100464941(ABCC1)
UMR: 103668839(ABCC1)
ORO: 101376465(ABCC1)
FCA: 101101279(ABCC1)
PTG: 102968778(ABCC1)
AJU: 106970556(ABCC1)
BTA: 281588(ABCC1)
BOM: 102280609(ABCC1)
BIU: 109578115(ABCC1)
PHD: 102328169(ABCC1)
CHX: 102177770(ABCC1)
OAS: 101110991(ABCC1)
SSC: 733619(ABCC1)
CFR: 102515231(ABCC1)
CDK: 105091152(ABCC1)
BACU: 103008581(ABCC1) 103009263
LVE: 103078230(ABCC1)
OOR: 101289237(ABCC1)
ECB: 791240(ABCC1)
EPZ: 103542517(ABCC1) 103558096
EAI: 106828820(ABCC1)
MYB: 102239517(ABCC1)
MYD: 102760334(ABCC1)
HAI: 109395236(ABCC1)
RSS: 109433845(ABCC1)
PALE: 102892429(ABCC1)
LAV: 100666408(ABCC1)
TMU: 101342579
MDO: 100023220(ABCC1)
SHR: 100932170(ABCC1)
OAA: 100087202(ABCC1)
GGA: 395416(ABCC1)
MGP: 100544305(ABCC1)
CJO: 107320624(ABCC1)
APLA: 101802999
ACYG: 106033447(ABCC1)
TGU: 100227445(ABCC1)
SCAN: 103817702
GFR: 102039176(ABCC1)
FAB: 101808560(ABCC1)
PHI: 102100964(ABCC1)
PMAJ: 107211108(ABCC1)
CCAE: 111936261(ABCC1)
CCW: 104684893
FPG: 101914887(ABCC1)
FCH: 102059643(ABCC1)
CLV: 102094737(ABCC1)
EGZ: 104126971
NNI: 104015166(ABCC1)
ACUN: 113485691(ABCC1)
ASN: 102378532
AMJ: 102573783(ABCC1)
PSS: 102444909
CMY: 102937562(ABCC1)
CPIC: 101947628(ABCC1)
ACS: 100559502(abcc1)
PVT: 110087057(ABCC1)
PBI: 103062593(ABCC1)
PMUR: 107283988(ABCC1)
GJA: 107109283(ABCC1)
XLA: 108701539(abcc1.L) 108701540(abcc6.L) 108702301
DRE: 100002010(abcc1) 566555(abcc6a)
CMK: 103178792(abcc1)
SPU: 591344(ABCC1)
DME: Dmel_CG6214(MRP)
DER: 6542983
DPE: 6603032
DSI: Dsimw501_GD23852(Dsim_GD23852)
DWI: 6643888
MDE: 101899511
AAG: 5565387
AME: 412217
BIM: 100742783
BTER: 100646583
SOC: 105197472
MPHA: 105839030
AEC: 105143093
ACEP: 105623280
PBAR: 105427107
HST: 105192220
DQU: 106750551
CFO: 105256288
LHU: 105670386
PGC: 109855782
OBO: 105282850
PCF: 106791501
NVI: 100120375
MDL: 103575185
TCA: 657826
NVL: 108566785
PMAC: 106714042
PRAP: 111001117
PXY: 105391710
ZNE: 110828594
CEL: CELE_F57C12.4(mrp-2) CELE_F57C12.5(mrp-1)
CBR: CBG08145(Cbr-mrp-1)
EGL: EGR_09216
HMG: 100199288
CIT: 102609764
CAM: 101514243
LJA: Lj0g3v0045069.1(Lj0g3v0045069.1) Lj0g3v0275429.1(Lj0g3v0275429.1) Lj0g3v0275429.2(Lj0g3v0275429.2) Lj0g3v0306379.1(Lj0g3v0306379.1) Lj0g3v0306379.2(Lj0g3v0306379.2) Lj1g3v4528420.1(Lj1g3v4528420.1) Lj3g3v0618270.1(Lj3g3v0618270.1) Lj3g3v2317940.1(Lj3g3v2317940.1) Lj3g3v2693530.1(Lj3g3v2693530.1) Lj3g3v3247340.1(Lj3g3v3247340.1) Lj5g3v1961180.1(Lj5g3v1961180.1) Lj5g3v1961190.1(Lj5g3v1961190.1)
PXB: 103929369
HBR: 110649202
POP: 7469392
CANN: 107845301
SOE: 110792524
DOSA: Os01t0173900-01(Os01g0173900) Os01t0356400-01(Os01g0356400) Os03t0142800-01(Os03g0142800) Os04t0209300-01(Os04g0209300) Os04t0588700-01(Os04g0588700) Os05t0196100-01(Os05g0196100) Os06t0561800-00(Os06g0561800)
ATS: 109750435(LOC109750435) 109758359(LOC109758359) 109759425(LOC109759425) 109773936(LOC109773936) 109773946(LOC109773946) 109774444(LOC109774444) 109775396(LOC109775396) 109782206(LOC109782206)
APRO: F751_6814
SCE: YDR135C(YCF1)
ERC: Ecym_4265
KMX: KLMA_10678(BPT1) KLMA_40176(YCF1)
NCS: NCAS_0B03470(NCAS0B03470)
NDI: NDAI_0J01150(NDAI0J01150)
TPF: TPHA_0C00960(TPHA0C00960) TPHA_0F00410(TPHA0F00410)
TBL: TBLA_0A03800(TBLA0A03800)
TDL: TDEL_0E05610(TDEL0E05610) TDEL_0F04300(TDEL0F04300)
KAF: KAFR_0B05630(KAFR0B05630) KAFR_0I01300(KAFR0I01300)
CAL: CAALFM_C702330WA(YCF1)
SLB: AWJ20_1275(YCF1) AWJ20_2293(YCF1) AWJ20_3641(YCF1) AWJ20_497(YCF1)
NCR: NCU09012
NTE: NEUTE1DRAFT122521(NEUTE1DRAFT_122521)
MGR: MGG_01674
BFU: BCIN_10g00650(Bcycf1)
MBE: MBM_00964
ANI: AN7729.2
ANG: ANI_1_480034(An03g04060)
ABE: ARB_03963
TVE: TRV_01828
PTE: PTT_16022
SPO: SPAC3F10.11c(abc2) SPBC359.05(abc3)
CNE: CNC05860
CNB: CNBC1320
ABP: AGABI1DRAFT119022(AGABI1DRAFT_119022)
ABV: AGABI2DRAFT151707(AGABI2DRAFT_151707)
MGL: MGL_0393
DDI: DDB_G0284867(abcC8)
DFA: DFA_01047(abcC3) DFA_04952 DFA_06298(abcC12) DFA_06664(abcC8) DFA_06666
SMIN: v1.2.005718.t1(symbB.v1.2.005718.t1) v1.2.013973.t1(symbB.v1.2.013973.t1) v1.2.014963.t1(symbB.v1.2.014963.t1) v1.2.023547.t1(symbB.v1.2.023547.t1) v1.2.027690.t1(symbB.v1.2.027690.t1) v1.2.027690.t2(symbB.v1.2.027690.t2) v1.2.027690.t3(symbB.v1.2.027690.t3) v1.2.030730.t1(symbB.v1.2.030730.t1) v1.2.032089.t1(symbB.v1.2.032089.t1) v1.2.032880.t1(symbB.v1.2.032880.t1) v1.2.035158.t1(symbB.v1.2.035158.t1) v1.2.037762.t1(symbB.v1.2.037762.t1) v1.2.040950.t1(symbB.v1.2.040950.t1)
BEX: A11Q_576
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1360704
  Authors
Cole SP, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AM, Deeley RG
  Title
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.
  Journal
Science 258:1650-4 (1992)
DOI:10.1126/science.1360704
  Sequence
[hsa:4363]
Reference
PMID:8626454
  Authors
Li ZS, Szczypka M, Lu YP, Thiele DJ, Rea PA
  Title
The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump.
  Journal
J Biol Chem 271:6509-17 (1996)
DOI:10.1074/jbc.271.11.6509

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