KEGG   ORTHOLOGY: K05666Help
Entry
K05666                      KO                                     

Name
ABCC2
Definition
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
Pathway
ko01523  Antifolate resistance
ko01524  Platinum drug resistance
ko02010  ABC transporters
ko04976  Bile secretion
Disease
H00208  Hyperbilirubinemia
H02056  Dubin-Johnson syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Membrane transport
   02010 ABC transporters
    K05666  ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
 Organismal Systems
  Digestive system
   04976 Bile secretion
    K05666  ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
 Human Diseases
  Drug resistance
   01524 Platinum drug resistance
    K05666  ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
   01523 Antifolate resistance
    K05666  ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
Transporters [BR:ko02000]
 ABC Transporters, Eukaryotic Type
  ABCC (CFTR/MRP) subfamily
   ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
    K05666  ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
BRITE hierarchy
Other DBs
TC: 3.A.1.208.2
Genes
HSA: 1244(ABCC2)
PTR: 104008275(ABCC2)
PPS: 100993869(ABCC2)
GGO: 101135234(ABCC2)
PON: 100445119(ABCC2)
NLE: 100600419(ABCC2)
MCC: 574169(ABCC2)
MCF: 102144998(ABCC2)
CSAB: 103216374(ABCC2)
RRO: 104656464(ABCC2)
RBB: 108535042(ABCC2)
CJC: 100411692(ABCC2)
SBQ: 101051015(ABCC2)
MMU: 12780(Abcc2)
RNO: 25303(Abcc2)
CGE: 100689220(Abcc2)
NGI: 103733168(Abcc2)
HGL: 101716089(Abcc2)
CCAN: 109681482(Abcc2)
OCU: 100343242(ABCC2)
TUP: 102499089(ABCC2)
CFA: 403632(ABCC2)
AML: 100465425(ABCC2)
UMR: 103658893(ABCC2)
ORO: 101362740(ABCC2)
FCA: 101085924(ABCC2)
PTG: 102955313(ABCC2)
AJU: 106966857(ABCC2)
BTA: 520925(ABCC2)
BOM: 102283570(ABCC2)
BIU: 109578988(ABCC2)
PHD: 102335808(ABCC2)
CHX: 102179626(ABCC2)
OAS: 101119776(ABCC2)
SSC: 397535(ABCC2)
CFR: 102504762(ABCC2)
CDK: 105084309(ABCC2)
BACU: 103012547(ABCC2)
LVE: 103082826(ABCC2)
OOR: 101279380(ABCC2)
ECB: 100060654(ABCC2)
EPZ: 103563172(ABCC2)
EAI: 106846699(ABCC2)
MYB: 102260793(ABCC2)
MYD: 102762700(ABCC2)
HAI: 109379606(ABCC2)
PALE: 102894298(ABCC2)
LAV: 100666918(ABCC2)
TMU: 101361831
MDO: 100020524(ABCC2)
SHR: 100925041(ABCC2)
OAA: 100090079(ABCC2)
GGA: 423828(ABCC2)
MGP: 100303700(ABCC2)
CJO: 107316078(ABCC2)
APLA: 101800808(ABCC2)
ACYG: 106045451(ABCC2)
TGU: 100217849 100222848(ABCC2)
GFR: 102043388(ABCC2)
FAB: 101820350(ABCC2)
PHI: 102110444(ABCC2)
PMAJ: 107206687(ABCC2)
CCW: 104695982(ABCC2)
FPG: 101920069(ABCC2)
FCH: 102053333(ABCC2)
CLV: 102096013(ABCC2)
EGZ: 104129073(ABCC2)
AAM: 106494706(ABCC2)
ASN: 102374535(ABCC2)
PSS: 102461169
CMY: 102947303(ABCC2)
CPIC: 101939524(ABCC2)
ACS: 100563787(abcc2)
PVT: 110084032(ABCC2)
PBI: 103055117(ABCC2)
GJA: 107121134(ABCC2)
XLA: 108695765(abcc2.L)
XTR: 100485020(abcc2)
NPR: 108791074(ABCC2)
DRE: 393561(abcc2)
SRX: 107758572
SANH: 107654078 107699143(abcc2)
IPU: 108260913(abcc2)
TRU: 101061938(abcc2)
LCO: 104929866(abcc2)
NCC: 104955146(abcc2)
NFU: 107375667(abcc2)
CSEM: 103387391(abcc2)
LCF: 108888309(abcc2)
HCQ: 109512715(abcc2)
BPEC: 110157252(abcc2)
SASA: 106576843(abcc2)
ELS: 105005797(abcc2)
SFM: 108918144(abcc2)
LCM: 102345232(ABCC2)
CMK: 103186569(abcc2)
OBI: 106868811
CRB: 17886906
LJA: Lj0g3v0041899.1(Lj0g3v0041899.1) Lj0g3v0088939.1(Lj0g3v0088939.1) Lj0g3v0188219.1(Lj0g3v0188219.1) Lj0g3v0211629.1(Lj0g3v0211629.1) Lj0g3v0222689.1(Lj0g3v0222689.1) Lj0g3v0249719.1(Lj0g3v0249719.1) Lj0g3v0249719.2(Lj0g3v0249719.2) Lj0g3v0300949.1(Lj0g3v0300949.1) Lj0g3v0317109.1(Lj0g3v0317109.1) Lj0g3v0317109.3(Lj0g3v0317109.3) Lj1g3v4104820.1(Lj1g3v4104820.1) Lj1g3v4896960.1(Lj1g3v4896960.1) Lj2g3v0727390.1(Lj2g3v0727390.1) Lj5g3v1630010.1(Lj5g3v1630010.1) Lj5g3v1630010.2(Lj5g3v1630010.2) Lj6g3v0781010.1(Lj6g3v0781010.1) Lj6g3v1447650.1(Lj6g3v1447650.1)
DOSA: Os01t0902100-00(Os01g0902100) Os04t0620066-00(Os04g0620066) Os12t0562700-00(Os12g0562700)
OBR: 102721035
SITA: 101769695
VCN: VOLCADRAFT_56442(mrp4)
DPP: DICPUDRAFT_55519(ABCC3)
SMIN: v1.2.030833.t1(symbB.v1.2.030833.t1)
SPAR: SPRG_06375
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8797578
  Authors
Taniguchi K, Wada M, Kohno K, Nakamura T, Kawabe T, Kawakami M, Kagotani K, Okumura K, Akiyama S, Kuwano M
  Title
A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation.
  Journal
Cancer Res 56:4124-9 (1996)
  Sequence
[hsa:1244]
Reference
  Authors
Klaassen CD, Aleksunes LM
  Title
Xenobiotic, bile acid, and cholesterol transporters: function and regulation.
  Journal
Pharmacol Rev 62:1-96 (2010)
DOI:10.1124/pr.109.002014

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