KEGG   ORTHOLOGY: K05687Help
Entry
K05687                      KO                                     

Name
PARK7
Definition
protein DJ-1 [EC:3.5.1.124]
Pathway
ko05012  Parkinson's disease
Disease
H00057  Parkinson's disease (PD)
H01600  Parkinsonian syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Neurodegenerative diseases
   05012 Parkinson's disease
    K05687  PARK7; protein DJ-1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.124  protein deglycase
     K05687  PARK7; protein DJ-1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C56: PfpI endopeptidase family
   K05687  PARK7; protein DJ-1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K05687  PARK7; protein DJ-1
BRITE hierarchy
Other DBs
GO: 0036524
Genes
HSA: 11315(PARK7)
PTR: 465864 746063(PARK7)
PPS: 100969783(PARK7)
GGO: 101135675(PARK7)
PON: 100447504(PARK7)
NLE: 100590226(PARK7)
MCC: 708377(PARK7)
MCF: 101865893(PARK7)
CSAB: 103225666(PARK7)
RRO: 104657558(PARK7)
RBB: 108517940(PARK7)
CJC: 100413204(PARK7) 108588492
SBQ: 101052951(PARK7)
MMU: 57320(Park7)
RNO: 117287(Park7)
CGE: 100759195(Park7)
NGI: 103725143(Park7)
HGL: 101723322(Park7)
CCAN: 109697924(Park7)
OCU: 100352938(PARK7)
TUP: 102470939(PARK7) 102474007
CFA: 479595(PARK7)
AML: 100475637(PARK7)
UMR: 103666687(PARK7)
ORO: 101380867(PARK7)
FCA: 101092868(PARK7)
PTG: 102959550(PARK7)
AJU: 106982200(PARK7)
BTA: 511268(PARK7)
BOM: 102288078(PARK7)
BIU: 109570573(PARK7)
PHD: 102315555(PARK7)
CHX: 102177646(PARK7)
OAS: 101119489(PARK7)
SSC: 780404(PARK7)
CFR: 102503983(PARK7)
CDK: 105106986(PARK7)
BACU: 103019344(PARK7)
LVE: 103082032(PARK7)
OOR: 101275264(PARK7)
ECB: 100052123(PARK7)
EPZ: 103561708(PARK7)
EAI: 106844319(PARK7)
MYB: 102263235(PARK7)
MYD: 102774693(PARK7)
HAI: 109381309(PARK7)
RSS: 109455299(PARK7)
PALE: 102884675(PARK7)
LAV: 100664838(PARK7)
TMU: 101357070
MDO: 100010357(PARK7)
SHR: 100923337(PARK7)
OAA: 100073498(PARK7)
GGA: 395277(PARK7)
MGP: 100544576(PARK7)
CJO: 107323475(PARK7)
APLA: 101794503(PARK7)
ACYG: 106047231(PARK7)
TGU: 100190506(PARK7) 100221757
GFR: 102045424(PARK7)
FAB: 101810201(PARK7)
PHI: 102112820(PARK7)
PMAJ: 107213629(PARK7)
CCW: 104693267(PARK7)
FPG: 101920065(PARK7)
FCH: 102046650(PARK7)
CLV: 102092024(PARK7)
EGZ: 104132789(PARK7)
AAM: 106496706(PARK7)
ASN: 102383069(PARK7)
AMJ: 102576304(PARK7)
PSS: 102460414(PARK7)
CMY: 102930935(PARK7)
CPIC: 101952912(PARK7)
ACS: 100551640(park7)
PVT: 110082464(PARK7)
PBI: 103055741(PARK7)
GJA: 107108653(PARK7)
XLA: 399179(park7.L)
XTR: 548568(park7)
NPR: 108783953(PARK7) 108796089
DRE: 449674(park7)
SRX: 107708261
IPU: 108255284(park7)
AMEX: 103030353(park7)
TRU: 101065925(park7)
LCO: 104919346(park7)
NCC: 104963216(park7)
MZE: 101464488(park7)
OLA: 100049299(park7)
XMA: 102227669(park7)
PRET: 103464454(park7)
NFU: 107385278(park7)
CSEM: 103385637(park7)
LCF: 108899924(park7)
HCQ: 109529237(park7)
BPEC: 110168456(park7)
SASA: 100136349(dj-1) 100286560(park7)
ELS: 105017254(park7)
SFM: 108918226(park7)
LCM: 102361342(PARK7)
CMK: 103181420(park7)
CIN: 100178410
SPU: 579485
APLC: 110979135
SKO: 100374964
DSI: Dsimw501_GD21547(Dsim_GD21547) Dsimw501_GD25730(Dsim_GD25730)
MDE: 101899019
AAG: 5564065
AME: 551882(GB15202)
BIM: 100746681
BTER: 100652254
SOC: 105194188
AEC: 105143166
ACEP: 105627554
PBAR: 105427177
HST: 105189556
CFO: 105254489
LHU: 105677024
PGC: 109862046
NVI: 100113484
TCA: 662087
DPA: 109544051
BMOR: 100422789(BmDJ-1beta)
PMAC: 106708309
PRAP: 110998205
API: 100165029
DNX: 107173112
ZNE: 110832294
FCD: 110852136
TUT: 107369780
CEL: CELE_B0432.2(djr-1.1) CELE_C49G7.11(djr-1.2)
CBR: CBG07015(Cbr-djr-1.2) CBG07016(Cbr-djr-1.1)
BMY: Bm1_07685
TSP: Tsp_11803
CRG: 105330226
MYI: 110462923
OBI: 106867205
LAK: 106174742
SHX: MS3_06918
EPA: 110234343
ADF: 107351224
HMG: 100211338
AQU: 100636722
PNO: SNOG_07399(SNOG_07398)
PTE: PTT_13806
ABP: AGABI1DRAFT121441(AGABI1DRAFT_121441)
ABV: AGABI2DRAFT187606(AGABI2DRAFT_187606)
MGL: MGL_3627
SCL: sce6209
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Shendelman S, Jonason A, Martinat C, Leete T, Abeliovich A
  Title
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation.
  Journal
PLoS Biol 2:e362 (2004)
DOI:10.1371/journal.pbio.0020362
  Sequence
[hsa:11315]
Reference
  Authors
Clements CM, McNally RS, Conti BJ, Mak TW, Ting JP
  Title
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2.
  Journal
Proc Natl Acad Sci U S A 103:15091-6 (2006)
DOI:10.1073/pnas.0607260103
  Sequence
[hsa:11315] [mmu:57320]
Reference
  Authors
Richarme G, Mihoub M, Dairou J, Bui LC, Leger T, Lamouri A
  Title
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
  Journal
J Biol Chem 290:1885-97 (2015)
DOI:10.1074/jbc.M114.597815
  Sequence
[hsa:11315]

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