KEGG   ORTHOLOGY: K05688
Entry
K05688                      KO                                     

Name
PINK1
Definition
PTEN induced putative kinase 1 [EC:2.7.11.1]
Pathway
ko04137  Mitophagy - animal
ko05012  Parkinson disease
ko05014  Amyotrophic lateral sclerosis
ko05022  Pathways of neurodegeneration - multiple diseases
Disease
H00057  Parkinson disease
H01600  Parkinsonian syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K05688  PINK1; PTEN induced putative kinase 1
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    K05688  PINK1; PTEN induced putative kinase 1
   05014 Amyotrophic lateral sclerosis
    K05688  PINK1; PTEN induced putative kinase 1
   05022 Pathways of neurodegeneration - multiple diseases
    K05688  PINK1; PTEN induced putative kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05688  PINK1; PTEN induced putative kinase 1
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05688  PINK1; PTEN induced putative kinase 1
   03029 Mitochondrial biogenesis
    K05688  PINK1; PTEN induced putative kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K05688  PINK1; PTEN induced putative kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  NKF2 family
   K05688  PINK1; PTEN induced putative kinase 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    K05688  PINK1; PTEN induced putative kinase 1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    K05688  PINK1; PTEN induced putative kinase 1
Genes
HSA: 65018(PINK1)
PTR: 749028(PINK1)
PPS: 100991148(PINK1)
GGO: 101125489(PINK1)
PON: 100443445(PINK1)
NLE: 100599956(PINK1) 105740041 115835845
MCC: 706037(PINK1)
MCF: 102125675(PINK1)
CSAB: 103225450(PINK1)
RRO: 104663205(PINK1)
RBB: 108515300(PINK1)
CJC: 100412264(PINK1)
SBQ: 101037834(PINK1)
MMU: 68943(Pink1)
MCAL: 110292810(Pink1)
MPAH: 110323093(Pink1)
RNO: 298575(Pink1)
MUN: 110544995(Pink1)
CGE: 100757303(Pink1)
NGI: 103738564(Pink1)
HGL: 101716045(Pink1)
CCAN: 109689686(Pink1)
OCU: 100350666(PINK1)
TUP: 102494988(PINK1)
CFA: 100688445(PINK1)
VVP: 112929829(PINK1)
AML: 100465867(PINK1)
UMR: 103666590(PINK1)
UAH: 113268560(PINK1)
ORO: 101381501(PINK1)
ELK: 111154572
FCA: 101093033(PINK1)
PTG: 102955123(PINK1)
PPAD: 109274247(PINK1)
AJU: 106987997(PINK1)
BTA: 510683(PINK1)
BOM: 102277915(PINK1)
BIU: 109576174(PINK1)
BBUB: 102401425(PINK1)
CHX: 102190832(PINK1)
OAS: 101102131(PINK1)
SSC: 100515613(PINK1)
CFR: 102521586(PINK1)
CDK: 105088855(PINK1)
BACU: 103003466(PINK1)
LVE: 103070110(PINK1)
OOR: 101287390(PINK1)
DLE: 111163436(PINK1)
PCAD: 102994189(PINK1)
ECB: 100071784(PINK1)
EPZ: 103541347(PINK1)
EAI: 106840050(PINK1)
MYB: 102242404(PINK1)
MYD: 102757961(PINK1)
MNA: 107538319(PINK1)
HAI: 109395562(PINK1)
DRO: 112298995(PINK1)
PALE: 102889368(PINK1)
RAY: 107513041(PINK1)
MJV: 108398638(PINK1)
LAV: 100671477(PINK1)
TMU: 101344541
MDO: 100027082(PINK1)
SHR: 100928885(PINK1)
PCW: 110198718(PINK1)
OAA: 100089816(PINK1)
MGP: 100540660(PINK1)
CJO: 107323259(PINK1)
NMEL: 110408508(PINK1)
APLA: 101789396(PINK1)
ACYG: 106040125(PINK1)
TGU: 100229816(PINK1)
LSR: 110472245(PINK1)
SCAN: 103824351(PINK1)
GFR: 102038690(PINK1)
FAB: 101822075(PINK1)
PHI: 102103989(PINK1)
PMAJ: 107213518(PINK1)
CCAE: 111938463(PINK1)
CCW: 104697553(PINK1)
ETL: 114068716(PINK1)
FPG: 101915366(PINK1)
FCH: 102053946(PINK1)
CLV: 102093865(PINK1)
EGZ: 104133158(PINK1)
NNI: 104011210(PINK1)
ACUN: 113487964(PINK1)
PADL: 103918066(PINK1)
AAM: 106493427(PINK1)
ASN: 106723111(PINK1)
AMJ: 102574908(PINK1)
PSS: 102444248(PINK1)
CMY: 102939538(PINK1)
CPIC: 101943102(PINK1)
PVT: 110072691(PINK1)
PBI: 103059482(PINK1)
PMUR: 107291375(PINK1)
TSR: 106547436(PINK1)
PMUA: 114602388(PINK1)
GJA: 107124402(PINK1)
DRE: 494085(pink1)
IPU: 108275846(pink1)
PHYP: 113530970(pink1)
AMEX: 103044294(pink1)
EEE: 113570339(pink1)
TRU: 101064886(pink1)
LCO: 104937209(pink1)
MZE: 101472469(pink1)
ONL: 100701609(pink1)
OLA: 101159103(pink1)
XMA: 102234169(pink1)
XCO: 114140467(pink1)
PRET: 103467817(pink1)
CVG: 107095066(pink1)
NFU: 107390418(pink1)
KMR: 108237629(pink1)
ALIM: 106529073(pink1)
AOCE: 111562744(pink1)
CSEM: 103385276(pink1)
POV: 109641931(pink1) 109646196
LCF: 108888646 108888944(pink1)
SDU: 111235113(pink1)
SLAL: 111669380(pink1)
BPEC: 110159396(pink1)
MALB: 109951219(pink1)
SASA: 106572550(pink1)
OTW: 112216273
SALP: 111976414(pink1)
ELS: 105028694(pink1)
SFM: 108939374(pink1)
PKI: 111855717(pink1)
LCM: 102358303(PINK1)
CMK: 103187676(pink1)
RTP: 109927832(pink1)
BFO: 118430210
SPU: 100893139
APLC: 110979101
SKO: 102809770
DER: 6551487
DSI: Dsimw501_GD24757(Dsim_GD24757)
DSR: 110183537
DPE: 6600224
DMN: 108154768
DWI: 6652989
DMO: Dmoj_GI21816(Dmoj_Tes31)
DAZ: 108619685
DNV: 108656938
DHE: 111597360
MDE: 101900190
LCQ: 111682780
AAG: 5575049
AME: 550929
BIM: 100745293
BTER: 100648193
CCAL: 108625716
OBB: 114872188
SOC: 105205113
MPHA: 105834461
AEC: 105154146
ACEP: 105622703
VEM: 105558954
HST: 105190066
DQU: 106741965
CFO: 105250504
LHU: 105677360
PGC: 109863555
OBO: 105286353
PCF: 106792545
NVI: 100122372
CSOL: 105360233
MDL: 103580166
TCA: 656767
DPA: 109543781
NVL: 108568702
API: 100169003
DNX: 107170068
AGS: 114120860
RMD: 113552394
BTAB: 109041087
CLEC: 106670804
ZNE: 110830315
FCD: 110845391
PVM: 113815108
TUT: 107371826
DPTE: 113798099
CSCU: 111632515
PTEP: 107449337
CEL: CELE_EEED8.9(pink-1)
BMY: Bm1_23785
PCAN: 112556854
MYI: 110460906
OBI: 106876772
LAK: 106175425
SHX: MS3_00077
NVE: 5519302
EPA: 110244759
ADF: 107352394
AMIL: 114962897
PDAM: 113679963
SPIS: 111320823
DGT: 114533614
AQU: 100631577
 » show all
Reference
  Authors
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrane J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, Li C, Tieu K, Przedborski S
  Title
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.
  Journal
Proc Natl Acad Sci U S A 107:378-83 (2010)
DOI:10.1073/pnas.0911187107
  Sequence
[hsa:65018]

DBGET integrated database retrieval system