KEGG   ORTHOLOGY: K05759Help
Entry
K05759                      KO                                     

Name
PFN
Definition
profilin
Pathway
ko04013  MAPK signaling pathway - fly
ko04015  Rap1 signaling pathway
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K05759  PFN; profilin
   04013 MAPK signaling pathway - fly
    K05759  PFN; profilin
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K05759  PFN; profilin
 Human Diseases
  Infectious diseases
   05132 Salmonella infection
    K05759  PFN; profilin
   05131 Shigellosis
    K05759  PFN; profilin
Membrane trafficking [BR:ko04131]
 Others
  Actin-binding proteins
   Others
    K05759  PFN; profilin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Profilin
     K05759  PFN; profilin
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K05759  PFN; profilin
BRITE hierarchy
Genes
HSA: 345456(PFN3) 375189(PFN4) 5216(PFN1) 5217(PFN2)
PTR: 100611207(PFN4) 460989(PFN2) 471759(PFN3) 748477(PFN1)
PPS: 100971072(PFN4) 100983596(PFN1) 100985836(PFN2) 100994866(PFN3)
GGO: 101123856(PFN3) 101139387(PFN2) 101141125(PFN1) 101141207(PFN4)
PON: 100173558(PFN2) 100432952(PFN1) 100433388(PFN3) 100433827 100437462(PFN4)
NLE: 100585055(PFN4) 100586031(PFN3) 100596575(PFN2) 100607206(PFN1)
MCC: 703982(PFN3) 704416(PFN4) 710753(PFN1) 713460(PFN2)
MCF: 101925958(PFN2) 102125524(PFN3) 102134841(PFN4) 102139180(PFN1)
CSAB: 103220669(PFN4) 103221840 103241491(PFN2) 103242213(PFN1) 103245051(PFN3)
RRO: 104657099(PFN2) 104658452(PFN4) 104663079(PFN1) 104680458(PFN3)
RBB: 108518278(PFN2) 108523453 108524810(PFN1) 108543038(PFN4) 108544776(PFN3)
CJC: 100386114(PFN4) 100395089(PFN1) 100404606(PFN2) 100413264(PFN3)
SBQ: 101032278(PFN2) 101033074(PFN1) 101037405(PFN4) 101051848(PFN3)
MMU: 18643(Pfn1) 18645(Pfn2) 382562(Pfn4) 75477(Pfn3)
RNO: 100909840 102551431 171436(Mk1) 494222(Pfn4) 64303(Pfn1) 685936(Pfn3) 81531(Pfn2)
CGE: 100753478(Pfn1) 100757165 100760079(Pfn4) 100770381(Pfn2) 100771269(Pfn3)
HGL: 101709082(Pfn4) 101719532(Pfn1) 101722241(Pfn3) 101725935(Pfn2)
CCAN: 109675600 109681535(Pfn2) 109684734(Pfn1) 109685779(Pfn3) 109703025(Pfn4)
OCU: 100340735(PFN4) 100350198(PFN1) 100356070 100357380(PFN3) 100358541(PFN2)
TUP: 102473053(PFN3) 102477876(PFN2) 102503239(PFN1)
CFA: 100683352(PFN2) 106558389 489091(PFN3) 607397(PFN1) 610829(PFN4)
AML: 100466871(PFN1) 100471904 100472573(PFN4) 100475516(PFN3) 100482446(PFN2)
ORO: 101371057(PFN4) 101371877 101378166(PFN3) 101380509(PFN2) 101386277(PFN1)
FCA: 101091824(PFN1) 101095411(PFN4) 101098924(PFN3) 101099994(PFN2) 101101369
PTG: 102955353(PFN1) 102962391 102966154(PFN4) 102966655(PFN2) 102968383(PFN3)
AJU: 106972488(PFN1) 106975168(PFN2) 106975371(PFN3) 106983161 106986692(PFN4)
BTA: 508874(PFN4) 513895(PFN1) 521379(PFN3) 539034(PFN2)
BOM: 102269030(PFN2) 102269243 102270896(PFN3) 102275654(PFN1) 102280202(PFN4)
BIU: 109555128 109559290(PFN2) 109561903(PFN3) 109566339(PFN4) 109573782(PFN1)
SSC: 100512494(PFN1) 100521444(PFN4) 100621523(PFN2) 102159063 106508714(PFN3)
CDK: 105099591(PFN3) 105100025(PFN4) 105101469(PFN1) 105107141
BACU: 103003778(PFN4) 103007008(PFN2) 103008505 103011382(PFN1) 103017043(PFN3)
OOR: 101277487(PFN3) 101281814(PFN4) 101285162 101285419(PFN1) 101286818(PFN2)
ECB: 100056163(PFN4) 100061295(PFN1) 100146754(PFN3) 100630364(PFN2) 102148861
EPZ: 103539970(PFN3) 103543790 103547830(PFN4) 103560657(PFN1) 103563312(PFN2)
EAI: 106825648(PFN1) 106827124(PFN3) 106836223 106839821(PFN4)
MYB: 102240210(PFN2) 102244910(PFN4) 102248499(PFN1) 102254975(PFN3)
MYD: 102751567(PFN4) 102759225(PFN1) 102765189(PFN2)
HAI: 109386484(PFN4) 109389743(PFN3) 109390069 109392710(PFN2) 109394645(PFN1)
RSS: 109434246(PFN3) 109435123(PFN4) 109436513(PFN1) 109438788 109456524(PFN2)
PALE: 102881675(PFN3) 102885079(PFN4) 102891169(PFN1) 102894047(PFN2) 102896555
LAV: 100654902(PFN1) 100662813(PFN3) 100673113(PFN2) 100673676(PFN4) 104846137
MDO: 100012072(PFN2) 100016522(PFN1) 100031959(PFN3) 107650459(PFN4)
SHR: 100922424(PFN3) 100924653(PFN2) 100935051(PFN1)
OAA: 100076098(PFN2) 100078341(PFN4) 100087807(PFN3)
GGA: 107053160(PFN4) 428564(PFN3) 771904(PFN2)
MGP: 100544644(PFN3) 100545777(PFN4) 100549018(PFN2)
CJO: 107311001(PFN3) 107312268(PFN4) 107318404(PFN2)
APLA: 101798025(PFN2) 101802089(PFN4)
ACYG: 106047683(PFN2)
TGU: 100226552(PFN2)
GFR: 102036125(PFN2)
FAB: 101819377(PFN2) 107603480
PHI: 102112934(PFN2) 102113786(PFN1) 106628191
PMAJ: 107198970(PFN1) 107208818(PFN2)
CCW: 104685735 104688181(PFN2)
FPG: 101912552(PFN2) 101921354(PFN3) 101922030(PFN4)
FCH: 102046982(PFN2) 102048750 102058676(PFN4)
CLV: 102087205(PFN3) 102096386(PFN2) 110364409(PFN4)
AAM: 106484201(PFN2) 106490391(PFN3)
ASN: 102372738 102373024(PFN2) 102377989(PFN1) 102380160(PFN3) 102387357(PFN4)
AMJ: 102563468(PFN2) 102568505(PFN3) 102574628 106737658(PFN4) 109281004(PFN1)
PSS: 102452372(PFN4) 102454092 102456768(PFN3) 102460168(PFN2) 102460555(PFN1)
CMY: 102929378(Profilin-1) 102930726(Profilin-3) 102937397(Profilin-1) 102938187(PFN4) 102940947(PFN2)
CPIC: 101945113(PFN1) 101946802(PFN3) 101947546(PFN2) 101949765(PFN4)
ACS: 100552505(pfn3) 100560832(pfn2)
PVT: 110070190(PFN4) 110073058(PFN2) 110075399(PFN3) 110082379(PFN1)
PBI: 103054709 103059791(PFN4) 103063030(PFN2) 103064957(PFN3)
GJA: 107107722(PFN4) 107114138 107121971(PFN2) 107122301(PFN3) 107124432(PFN1)
XLA: 108717462 108718266(pfn4.S) 380475(pfn2.L) 398635(pfn1.S) 735169(pfn1.L)
XTR: 100170559(pfn1) 100495970(pfn4) 548852(pfn2)
NPR: 108796837(PFN2) 108803688(PFN4)
DRE: 321383(pfn2l) 394235(pfn2) 556873(si:ch211-175f11.5)
IPU: 100528281(pfn2) 108275705
LCO: 104921276 104923512(pfn2) 104937620(pfn1)
NCC: 104947425(pfn2) 104951932
CSEM: 103389936(pfn1) 103394187(pfn2) 103395841
SASA: 106568266 106568739(PROF2) 106574126(pfn2) 106578240(PROF2) 106598797(PROF2) 106604893(pfn3) 106613487(PROF2)
CIN: 100181200
DME: Dmel_CG9553(chic)
DSI: Dsimw501_GD22617(Dsim_chic)
MDE: 101899736
AAG: 5577719
AME: 406154(PRF)
BIM: 100746087
BTER: 100650794
SOC: 105206360
AEC: 105155053
ACEP: 105620117
PBAR: 105432078
HST: 105192352
CFO: 105254784
LHU: 105671273
PGC: 109858460
NVI: 100114163
TCA: 659243(chic)
DPA: 109537572
NVL: 108569403
BMOR: 692652(PFN)
PMAC: 106719980
PRAP: 110999647
PXY: 105384065
ZNE: 110833489
FCD: 110858695
TUT: 107368551
CEL: CELE_F35C8.6(pfn-2) CELE_K03E6.6(pfn-3) CELE_Y18D10A.20(pfn-1)
CBR: CBG04366(Cbr-pfn-1) CBG08063(Cbr-pfn-3)
BMY: Bm1_21620
TSP: Tsp_12759
HMG: 100200741
ATH: AT2G19760(PRF1) AT2G19770(PRF5) AT4G29340(PRF4) AT4G29350(PFN2) AT5G56600(PRF3)
LJA: Lj2g3v0891240.1(Lj2g3v0891240.1) Lj4g3v3042750.1(Lj4g3v3042750.1) Lj4g3v3042770.1(Lj4g3v3042770.1)
MDM: 103400730 103400731(profilin) 103428897(GD4-1) 103443736(MDpf-1)
RCU: 8265127 8265128(pro1) 8273767
SLY: 101254907 101261989 543782(profilin) 543830 544018(PRO1)
DOSA: Os01t0191150-00(Os01g0191150) Os06t0152100-01(Os06g0152100) Os10t0323600-01(Os10g0323600) Os10t0323900-01(Os10g0323900)
ATS: 109750496(LOC109750496) 109762546(LOC109762546) 109768398(LOC109768398) 109776150(LOC109776150)
ZMA: 100283110 103636667 541662(PRO4) 542409(prf1) 542410(prf2) 542411(prf3) 542625(prf5)
CRE: CHLREDRAFT_181887(PRO1)
VCN: VOLCADRAFT_106260(prfA)
MIS: MICPUN_79195(PRO1)
APRO: F751_0324
SCE: YOR122C(PFY1)
ERC: Ecym_4510
KMX: KLMA_20614(PFY1)
NCS: NCAS_0H02070(NCAS0H02070)
NDI: NDAI_0C01580(NDAI0C01580)
TPF: TPHA_0E01740(TPHA0E01740)
TBL: TBLA_0A06500(TBLA0A06500)
TDL: TDEL_0D02620(TDEL0D02620)
KAF: KAFR_0D05040(KAFR0D05040)
PIC: PICST_35297(PFY1)
CAL: CAALFM_C108030WA(PFY1)
CAUR: QG37_03224
NCR: NCU06397
NTE: NEUTE1DRAFT116423(NEUTE1DRAFT_116423) NEUTE1DRAFT144645(NEUTE1DRAFT_144645)
MGR: MGG_06127
MAW: MAC_06398
MAJ: MAA_05077
CMT: CCM_04256
MBE: MBM_06248
ANI: AN2484.2
ANG: ANI_1_458124(An14g03180)
PTE: PTT_18654
SPO: SPAC4A8.15c(cdc3)
CNE: CNA05680
CNB: CNBA5480
ABP: AGABI1DRAFT115039(AGABI1DRAFT_115039)
ABV: AGABI2DRAFT77709(AGABI2DRAFT_77709)
MGL: MGL_0646
DDI: DDB_G0271142(proC) DDB_G0286187(proB) DDB_G0287125(proA)
DFA: DFA_08065(proB) DFA_10759(proA)
EHI: EHI_109900(128.t00012) EHI_176140(156.t00003)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3356709
  Authors
Kwiatkowski DJ, Bruns GA
  Title
Human profilin. Molecular cloning, sequence comparison, and chromosomal analysis.
  Journal
J Biol Chem 263:5910-5 (1988)
  Sequence
[hsa:5216]
Reference
  Authors
Shao J, Welch WJ, Diprospero NA, Diamond MI
  Title
Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation.
  Journal
Mol Cell Biol 28:5196-208 (2008)
DOI:10.1128/MCB.00079-08
  Sequence
[hsa:5216]

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