KEGG   ORTHOLOGY: K05765Help
Entry
K05765                      KO                                     

Name
CFL
Definition
cofilin
Pathway
ko04360  Axon guidance
ko04666  Fc gamma R-mediated phagocytosis
ko04810  Regulation of actin cytoskeleton
ko05133  Pertussis
ko05170  Human immunodeficiency virus 1 infection
Disease
H00698  Nemaline myopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05765  CFL; cofilin
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K05765  CFL; cofilin
  09158 Development
   04360 Axon guidance
    K05765  CFL; cofilin
 09160 Human Diseases
  09171 Infectious diseases: Bacterial
   05133 Pertussis
    K05765  CFL; cofilin
  09172 Infectious diseases: Viral
   05170 Human immunodeficiency virus 1 infection
    K05765  CFL; cofilin
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05765  CFL; cofilin
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05765  CFL; cofilin
   04147 Exosome
    K05765  CFL; cofilin
Membrane trafficking [BR:ko04131]
 Others
  Actin-binding proteins
   Others
    K05765  CFL; cofilin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    ADF / Cofilin
     K05765  CFL; cofilin
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K05765  CFL; cofilin
BRITE hierarchy
Genes
HSA: 1072(CFL1) 1073(CFL2)
PTR: 452853(CFL2) 745772(CFL1)
PPS: 100989724(CFL2) 103783331(CFL1) 103783923(CCDC125)
GGO: 101152594(CFL2) 101153774(CFL1)
PON: 100454363(CFL2) 103891788(CFL1)
NLE: 100591146(CFL1) 100594455(CFL2)
MCC: 693875(CFL2) 721882(CFL1)
MCF: 101866299(CFL1) 101866949(CFL2)
CSAB: 103224743 103228808(CFL2) 103241703(CFL1)
RRO: 104655970 104659082 104664809(CFL1) 104673366(CFL2)
RBB: 108518638(CFL1) 108532943 108538680(CFL2)
CJC: 100397668(CFL2) 103796391(CFL1)
SBQ: 101053279(CFL2) 104652856(CFL1) 104653222
MMU: 12631(Cfl1) 12632(Cfl2)
RNO: 29271(Cfl1) 366624(Cfl2)
CGE: 100757641(Cfl2) 100760435(Cfl1)
NGI: 103725002(Cfl1) 103731431(Cfl2)
HGL: 101713836(Cfl1) 101715697(Cfl2)
CCAN: 109687138(Cfl1) 109693957(Cfl2)
OCU: 100341589(CFL1) 100359205 108178303(CFL2)
CFA: 476022(CFL1) 490649(CFL2)
AML: 100464729(CFL1) 100468428(CFL2)
UMR: 103666200(CFL2) 103679469(CFL1)
ORO: 101363414(CFL2) 101378516(CFL1)
FCA: 101083089(CFL2) 101100251(CFL1)
PTG: 102959514(CFL2) 102970553(CFL1)
AJU: 106971215(CFL1) 106987106(CFL2)
BTA: 534553(CFL1) 539332(CFL2)
BOM: 102271978(CFL2) 102277395(CFL1)
BIU: 109554636(CFL1) 109575418(CFL2)
PHD: 102316281(CFL1) 102339960(CFL2)
CHX: 102170587(CFL1) 102180632(CFL2)
OAS: 101118388(CFL2) 494432(CFL1)
SSC: 445532(CFL1) 497233(CFL2)
CFR: 102513237(CFL1) 102518448(CFL2)
CDK: 105094171(CFL2) 105102587(CFL1)
BACU: 102998574(CFL1) 103000277(CFL2)
LVE: 103076856 103085070(CFL1) 103088851(CFL2)
OOR: 101272563(CFL1) 101275319 101286878(CFL2)
ECB: 100050494(CFL2) 100057603(CFL1)
EPZ: 103546412(CFL2) 103559372(CFL1)
EAI: 106827105(CFL2) 106833560(CFL1)
MYB: 102247446(CFL2) 102256765 102257903(CFL1)
MYD: 102759323(CFL1) 102766326(CFL2)
HAI: 109383900(CFL2) 109384191(CFL1)
RSS: 109450423(CFL1) 109457498(CFL2)
PALE: 102886318(CFL1) 102893502(CFL2)
LAV: 100653593(CFL1) 100663505(CFL2)
MDO: 100010809(CFL2)
SHR: 100923817(CFL1) 100929451
OAA: 100081338(CFL2)
GGA: 423320(CFL2)
MGP: 100549265(CFL2)
CJO: 107315052(CFL2)
APLA: 101793468(CFL2)
ACYG: 106031748(CFL2)
TGU: 100231500(CFL2)
GFR: 102035905(CFL2)
FAB: 101815068(CFL2)
PHI: 102111379(CFL2)
PMAJ: 107206355(CFL2)
CCAE: 111930025(CFL2)
CCW: 104684713(CFL2)
FPG: 101923199(CFL2)
FCH: 102047708(CFL2)
CLV: 102096851(CFL2)
EGZ: 104133308(CFL2)
AAM: 106482835(CFL2)
ASN: 102382000 102383164(CFL2)
AMJ: 102557891 102558369(CFL2)
PSS: 102455301(CFL2) 102459325(CFL1)
CMY: 102931401(CFL2) 102948032(CFL1)
CPIC: 101946904(CFL2) 101953269(CFL1)
ACS: 100553103(cfl2) 100566403
PVT: 110070042(CFL1) 110089303(CFL2)
PBI: 103056476(CFL2) 103062012
GJA: 107114813(CFL2) 107121075(CFL1)
XLA: 108699719(cfl2.S) 108716609 379172(cfl1.S) 379258(cfl1.L) 379282(dstn.S) 494995(cfl2.L)
XTR: 100038216(dstn) 407855(cfl1) 496574(cfl2)
NPR: 108784119(CFL1) 108789515 108795753(CFL2)
DRE: 321496(cfl1) 403001(cfl2) 406738(cfl1l)
IPU: 108261049(Cofilin-2) 108269238(cfl1) 108270478(cfl2)
TRU: 101064973 101066209(cfl1) 101071106(cfl2)
LCO: 104918318(dstn) 104931553(cfl1) 104939633(cfl2)
MZE: 101466267 101473000(cfl1) 101474530(cfl2)
XMA: 102224099(cfl2) 102227073(cfl1) 102227392
PRET: 103458109(cfl2) 103471656(cfl1) 103477215(dstn)
NFU: 107375572(dstn) 107378367(cfl1) 107391922(cfl2)
CSEM: 103381966(cfl2) 103390735(cfl1)
LCF: 108872518(cfl1) 108877129 108882352(cfl2)
SDU: 111220759(dstn) 111232421(cfl1) 111237172
BPEC: 110157100 110158853(cfl1) 110159226(cfl2)
MALB: 109951721 109957900(cfl1)
SASA: 100194616(cf12) 106563505(COF2) 106578802(COF2) 106589988(COF2) 106602033 106603165(COF2) 106604708(cof2) 106611761(COF2)
CIN: 100185305
SPU: 574611
DME: Dmel_CG4254(tsr) Dmel_CG6873(CG6873)
DSI: Dsimw501_GD15622(Dsim_GD15622) Dsimw501_GD24977(Dsim_GD24977)
DYA: Dyak_GE11491(Dyak_tsr) Dyak_GE15494
MDE: 101896929
AAG: 5579795
AME: 725718
BIM: 100746164
BTER: 100643436
SOC: 105193165
AEC: 105154023
ACEP: 105618144
PBAR: 105433067
HST: 105184032
DQU: 106741654
CFO: 105259326
LHU: 105678370
PGC: 109856904
PCF: 106791860
NVI: 100113672
MDL: 103576164
TCA: 656560
DPA: 109537692
NVL: 108566053
BMOR: 100101180
PMAC: 106708504
PRAP: 110997768
HAW: 110381486
PXY: 105393436
API: 100144915(Tsr)
DNX: 107166248
CLEC: 106668691
ZNE: 110838529
TUT: 107369845
CEL: CELE_C38C3.5(unc-60)
CBR: CBG06572(Cbr-unc-60) CBG06573
BMY: Bm1_22990
TSP: Tsp_03744
SHX: MS3_05026
EGL: EGR_03925
ATH: AT1G01750(ADF11) AT2G16700(ADF5) AT2G31200(ADF6) AT3G45990 AT3G46000(ADF2) AT3G46010(ADF1) AT4G00680(ADF8) AT4G25590(ADF7) AT4G34970(ADF9) AT5G52360(ADF10) AT5G59880(ADF3) AT5G59890(ADF4)
LJA: Lj0g3v0082449.1(Lj0g3v0082449.1) Lj0g3v0165859.1(Lj0g3v0165859.1) Lj1g3v4483790.1(Lj1g3v4483790.1) Lj2g3v2017590.1(Lj2g3v2017590.1) Lj3g3v3528600.1(Lj3g3v3528600.1) Lj4g3v0070940.1(Lj4g3v0070940.1) Lj4g3v2641100.1(Lj4g3v2641100.1) Lj5g3v0614390.1(Lj5g3v0614390.1) Lj5g3v2013650.1(Lj5g3v2013650.1)
DOSA: Os02t0663800-01(Os02g0663800) Os03t0243100-01(Os03g0243100) Os03t0780400-01(Os03g0780400) Os03t0820500-01(Os03g0820500) Os03t0820600-01(Os03g0820600) Os04t0555700-01(Os04g0555700) Os05t0113400-01(Os05g0113400) Os07t0484200-01(Os07g0484200) Os10t0521100-01(Os10g0521100) Os12t0628100-01(Os12g0628100)
ATS: 109732427(LOC109732427) 109748366(LOC109748366) 109748452(LOC109748452) 109751338(LOC109751338) 109752820(LOC109752820) 109758781(LOC109758781) 109759106(LOC109759106) 109763569(LOC109763569) 109784251(LOC109784251) 109786462(LOC109786462)
PPP: 112278178
VCN: VOLCADRAFT_68164(adfA)
APRO: F751_4475
SCE: YLL050C(COF1)
ERC: Ecym_8422
KMX: KLMA_80417(COF1)
NCS: NCAS_0C05960(NCAS0C05960)
NDI: NDAI_0H00160(NDAI0H00160)
TPF: TPHA_0F00150(TPHA0F00150)
TBL: TBLA_0E01170(TBLA0E01170)
TDL: TDEL_0G01890(TDEL0G01890)
KAF: KAFR_0L00180(KAFR0L00180)
CAL: CAALFM_C500370WA(COF1)
NCR: NCU01587
NTE: NEUTE1DRAFT117312(NEUTE1DRAFT_117312)
MGR: MGG_03164
SSCK: SPSK_01891
MAW: MAC_09573
MAJ: MAA_07686
CMT: CCM_04563
BFU: BCIN_07g05130(Bccof1)
MBE: MBM_05626
ANI: AN2317.2
ANG: ANI_1_596124(An14g04160)
CIM: CIMG_13032(CIMG06277)
ABE: ARB_07060
TVE: TRV_05993
PTE: PTT_07334
SPO: SPAC20G4.06c(adf1)
CNE: CNC05990
CNB: CNBC1190
ABP: AGABI1DRAFT85102(AGABI1DRAFT_85102)
ABV: AGABI2DRAFT223913(AGABI2DRAFT_223913)
MGL: MGL_3753
DDI: DDB_G0277833(cofA) DDB_G0291970(cofB)
DFA: DFA_07056(cofB)
EHI: EHI_197480(152.t00017)
PYO: PY17X_1138900(PY01091)
PCB: PCHAS_113700(PC000735.02.0)
TAN: TA06435
BBO: BBOV_IV008510(23.m06210)
CPV: cgd5_2800
TGO: TGME49_220400(ADF)
SMIN: v1.2.017676.t1(symbB.v1.2.017676.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nakano K, Kanai-Azuma M, Kanai Y, Moriyama K, Yazaki K, Hayashi Y, Kitamura N
  Title
Cofilin phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family.
  Journal
Exp Cell Res 287:219-27 (2003)
DOI:10.1016/S0014-4827(03)00136-8
  Sequence
[hsa:1072]
Reference
  Authors
Iida K, Yahara I
  Title
Cooperation of two actin-binding proteins, cofilin and Aip1, in Saccharomyces cerevisiae.
  Journal
Genes Cells 4:21-32 (1999)
DOI:10.1046/j.1365-2443.1999.00235.x
  Sequence
[sce:YLL050C]
Reference
PMID:2263493
  Authors
Ogawa K, Tashima M, Yumoto Y, Okuda T, Sawada H, Okuma M, Maruyama Y
  Title
Coding sequence of human placenta cofilin cDNA.
  Journal
Nucleic Acids Res 18:7169 (1990)
  Sequence
[hsa:1072]

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