KEGG   ORTHOLOGY: K05829
Entry
K05829                      KO                                     

Name
lysY, argC
Definition
LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase [EC:1.2.1.103 1.2.1.-]
Pathway
ko00220  Arginine biosynthesis
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
   00220 Arginine biosynthesis
    K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.103  [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase
     K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
    1.2.1.-  
     K05829  lysY, argC; LysW-gamma-L-alpha-aminoadipyl-6-phosphate/LysW-L-glutamyl-5-phosphate reductase
Other DBs
RN: R09777 R10931
COG: COG0002
Genes
ENF: AKI40_3666(argC1)
CARI: FNU76_03415(argC)
ADE: Adeh_0171
ACP: A2cp1_0191
AFW: Anae109_0180
ANK: AnaeK_0180
MXA: MXAN_5110(argC)
MSD: MYSTI_01367 MYSTI_05599
MYM: A176_001775
CCX: COCOR_02066(argC) COCOR_02384(argC1)
CCRO: CMC5_013340(argC)
HOH: Hoch_4934
PMW: B2K_22475
PSWU: SY83_08900
SGR: SGR_3479
SFA: Sfla_0120
STRP: F750_6904
SFI: SFUL_3351
SCI: B446_19850(lysY)
SPRI: SPRI_3643
SRW: TUE45_06897(argC_2)
SLAU: SLA_3044
SALJ: SMD11_6707(lysY)
SESP: BN6_56700
ASE: ACPL_7490(argC)
ACTS: ACWT_7360
PLK: CIK06_18385(argC)
CAI: Caci_6304
RCA: Rcas_3468
CAU: Caur_0335
CAG: Cagg_3596
HAU: Haur_3307
TRO: trd_1518(argC)
STI: Sthe_0216
ATM: ANT_12400(argC)
CAP: CLDAP_41080(argC)
DRA: DR_0963(argC)
DGE: Dgeo_0685
DGO: DGo_CA1602(argC)
DFC: DFI_07605
DGA: DEGR_14640(argC1)
TRA: Trad_1395
TTH: TT_C1542
TTJ: TTHA1904(argC)
TSC: TSC_c01930(argC1)
TAQ: TO73_0099
TBC: A0O31_00869(argC_1)
MRB: Mrub_2723
MRE: K649_08920(argC)
TTR: Tter_0319
TAI: Taci_0448
TLI: Tlie_1470
RMR: Rmar_0948
MRO: MROS_0164
CABY: Cabys_3149(argC)
PTO: PTO1472
FAI: FAD_0505(lysY)
CDIV: CPM_0548
PFU: PF1683
PFI: PFC_10190(argC)
PHO: PH1720(PH1720)
PAB: PAB0291(argC)
PYN: PNA2_0328
PYS: Py04_1635
TKO: TK0277
THS: TES1_0508
HHB: Hhub_3649(argC)
HJE: HacjB3_00985(argC)
HALH: HTSR_0665(argC)
HHSR: HSR6_0691(argC)
HSU: HLASF_2138(argC)
HSF: HLASA_2172(argC)
HMA: rrnAC2678(argC)
HHI: HAH_3082(argC)
NPH: NP_5260A(argC)
NMO: Nmlp_1242(argC)
HUT: Huta_1501
HTI: HTIA_1540
HMU: Hmuk_0773
HALL: LC1Hm_3289(argC)
HWA: HQ_3715A(argC)
HWC: Hqrw_4130(argC)
HVO: HVO_0045(argC)
HME: HFX_0045(argC)
HLA: Hlac_2615
HDF: AArcSl_0042(argC)
HTU: Htur_0327
NMG: Nmag_1760(argC)
NAT: NJ7G_0262
SALI: L593_07890(argC)
APE: APE_1462(lysY)
ACJ: ACAM_0921
IHO: Igni_0728
IIS: EYM_02375
IAG: Igag_1754
STO: STK_01950(argC_lysY)
SSO: SSO0155(argC)
SOL: Ssol_1133
SSOA: SULA_1169
SSOL: SULB_1170
SSOF: SULC_1168
SAI: Saci_0750(argC)
SACN: SacN8_03645(argC)
SACR: SacRon12I_03630(argC)
SID: M164_1990
SII: LD85_2245
SIH: SiH_1928
SIR: SiRe_1855
SIC: SiL_1837
MSE: Msed_0164
MCN: Mcup_1909
AHO: Ahos_0883
STEP: IC006_1902
PAI: PAE2881
PIS: Pisl_0276
PCL: Pcal_0373
PAS: Pars_0966
PYR: P186_1636
POG: Pogu_1380
TNE: Tneu_1837
CMA: Cmaq_1301
TTN: TTX_0120(lysY_argC)
TUZ: TUZN_1285
VDI: Vdis_0193
VMO: VMUT_1533
NMR: Nmar_1289
NIR: NSED_07155(argC)
NKR: NKOR_07275(argC)
NID: NPIRD3C_0835(argC)
NIN: NADRNF5_0667(argC)
NCT: NMSP_0399
NGA: Ngar_c29960(argC)
NVN: NVIE_016490(argC)
NEV: NTE_00734
TAA: NMY3_02222(argC2)
NFN: NFRAN_2984(lysY)
NCV: NCAV_1251(lysY)
NBV: T478_1044(argC)
NDV: NDEV_1624(argC)
KCR: Kcr_0809
BARB: AOA66_0020
CCAI: NAS2_0267
 » show all
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
  Sequence
[tth:TT_C1542]
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0750]

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