KEGG   ORTHOLOGY: K05857Help
Entry
K05857                      KO                                     

Name
PLCD
Definition
phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Pathway
ko00562  Inositol phosphate metabolism
ko01100  Metabolic pathways
ko04020  Calcium signaling pathway
ko04070  Phosphatidylinositol signaling system
ko04919  Thyroid hormone signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
Module
M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Disease
H01307  Nonsyndromic congenital nail disorder
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
   04070 Phosphatidylinositol signaling system
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
 09160 Human Diseases
  09166 Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
     K05857  PLCD; phosphatidylinositol phospholipase C, delta
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     K05857  PLCD; phosphatidylinositol phospholipase C, delta
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
 Endocytosis
  Macropinocytosis
   Phospholipase C
    K05857  PLCD; phosphatidylinositol phospholipase C, delta
BRITE hierarchy
Other DBs
RN: R03332 R03435 R10952
GO: 0004435
Genes
HSA: 113026(PLCD3) 5333(PLCD1) 84812(PLCD4)
PTR: 460267(PLCD1) 468279(PLCD3) 470647(PLCD4)
PPS: 100969236(PLCD1) 100980795(PLCD3) 100988032(PLCD4)
GGO: 101136081(PLCD4) 101139984(PLCD1) 101142984(PLCD3) 109025954
PON: 100171640(PLCD4) 100443819(PLCD3) 100462440(PLCD1)
NLE: 100596702(PLCD1) 100598366(PLCD4) 100604799(PLCD3)
MCC: 696860(PLCD1) 699569(PLCD4) 715924(PLCD3)
MCF: 101866682(PLCD1) 102122144(PLCD4) 102138566(PLCD3)
CSAB: 103217873(PLCD4) 103221069(PLCD1) 103243297(PLCD3)
RRO: 104654736(PLCD3) 104657452(PLCD1) 104660025(PLCD4)
RBB: 108512236(PLCD1) 108518456(PLCD4) 108532211(PLCD3)
CJC: 100395085(PLCD3) 100408539(PLCD4) 100408597(PLCD1)
SBQ: 101030401(PLCD4) 101045153(PLCD3) 101053112(PLCD1)
MMU: 18799(Plcd1) 18802(Plcd4) 72469(Plcd3)
RNO: 140693(Plcd4) 24655(Plcd1) 287745(Plcd3)
CGE: 100751509(Plcd1) 100751872(Plcd4) 100759620(Plcd3)
NGI: 103727720(Plcd4) 103738313(Plcd3) 103751602(Plcd1)
HGL: 101704621(Plcd3) 101704999(Plcd4) 101715010(Plcd1)
CCAN: 109678350(Plcd4) 109691551(Plcd3) 109698346(Plcd1)
OCU: 100347485(PLCD4) 100352032(PLCD3) 103347252(PLCD1)
TUP: 102468499(PLCD3) 102475249(PLCD4) 102500184(PLCD1)
CFA: 478910(PLCD4) 485586(PLCD1) 490929(PLCD3)
AML: 100469148(PLCD4) 100471021(PLCD3) 100476035(PLCD1)
UMR: 103662760(PLCD4) 103665878(PLCD3) 103682206(PLCD1)
ORO: 101364446(PLCD1) 101364713(PLCD3) 101372489(PLCD4)
FCA: 101086518(PLCD3) 101087777(PLCD1) 101090455(PLCD4)
PTG: 102952633(PLCD1) 102956201(PLCD4) 102963235(PLCD3)
AJU: 106966690(PLCD1) 106970106(PLCD4) 106988142(PLCD3)
BTA: 281986(PLCD1) 513057(PLCD3) 540771(PLCD4)
BOM: 102269641(PLCD3) 102270277 102273490(PLCD4) 106701107(PLCD1)
PHD: 102321405(PLCD1) 102324981(PLCD3) 102328353(PLCD4)
CHX: 102169343(PLCD4) 102184479(PLCD1) 102190639(PLCD3)
OAS: 101110367(PLCD1) 101111344(PLCD4) 101118035(PLCD3)
SSC: 100521111(PLCD3) 100627099(PLCD1) 397119(PLCD4)
CFR: 102506571(PLCD3) 102507363(PLCD1) 102515536(PLCD4)
CDK: 105090726(PLCD1) 105094408(PLCD3) 105096083(PLCD4)
BACU: 103014054(PLCD1) 103014562(PLCD3) 103019165(PLCD4)
LVE: 103073047(PLCD1) 103080679(PLCD3) 103081712(PLCD4)
OOR: 101271088(PLCD3) 101279487(PLCD1) 101282608(PLCD4)
ECB: 100054233(PLCD1) 100058665(PLCD4) 100064142(PLCD3)
EPZ: 103553904(PLCD1) 103554680(PLCD3) 103561954(PLCD4)
EAI: 106834270(PLCD1) 106836472(PLCD3) 106838452(PLCD4)
MYB: 102241313(PLCD3) 102252971(PLCD4) 102262661(PLCD1)
MYD: 102758829(PLCD4) 102760213(PLCD3) 102760355(PLCD1)
HAI: 109380562(PLCD4) 109385184(PLCD1) 109394976(PLCD3)
PALE: 102878454(PLCD1) 102884893(PLCD4) 102896686(PLCD3)
LAV: 100656701(PLCD3) 100660015(PLCD1) 100676480(PLCD4)
MDO: 100011291(PLCD4) 100024144(PLCD3)
SHR: 100916816(PLCD3) 100919591(PLCD4) 100933386(PLCD1)
OAA: 100083809(PLCD1)
GGA: 420416(PLCD1) 424214(PLCD4) 428279(PLCD3)
MGP: 100540750(PLCD4) 100542227(PLCD1) 100551436(PLCD3)
CJO: 107308792(PLCD1) 107316914(PLCD4) 107325007(PLCD3)
APLA: 101796325(PLCD1) 101796880(PLCD3) 101804382(PLCD4)
ACYG: 106036853(PLCD1) 106039320(PLCD4) 106046916(PLCD3)
TGU: 100224924 100227504(PLCD4) 100229323(PLCD1)
GFR: 102034984(PLCD4) 102040502(PLCD1) 102041993(PLCD3)
FAB: 101809831(PLCD3) 101816161(PLCD1) 101817537(PLCD4)
PHI: 102100115(PLCD4) 102100695(PLCD3) 102108822(PLCD1)
PMAJ: 107200537(PLCD1) 107207601(PLCD4) 107215288(PLCD3)
CCW: 104686410(PLCD1) 104693970(PLCD4) 104698537(PLCD3)
FPG: 101911097(PLCD3) 101919734(PLCD1) 101920700(PLCD4)
FCH: 102049427(PLCD1) 102050720(PLCD3) 102054061(PLCD4)
CLV: 102083893(PLCD4) 102086985(PLCD1) 102096927(PLCD3) 110363118
EGZ: 104130960(PLCD1) 104132360(PLCD3) 104132408(PLCD4)
AAM: 106494848(PLCD1) 106495647(PLCD3) 106499321
ASN: 102368121(PLCD1) 102387019(PLCD3)
AMJ: 102575027(PLCD3) 102576343(PLCD1)
PSS: 102455868(PLCD1) 102459349(PLCD4)
CMY: 102932314(PLCD1) 102935898(PLCD4) 102944425(PLCD3)
CPIC: 101933267(PLCD3) 101941573(PLCD1) 101944484(PLCD4)
ACS: 100552636(plcd4) 100559401(plcd3) 100567266(plcd1) 103282571
PVT: 110078238(PLCD4) 110081386(PLCD3) 110085836(PLCD1)
PBI: 103051665(PLCD4) 103053551(PLCD3) 103056024(PLCD1)
XLA: 108700851(plcd3.L) 108702553(plcd3.S) 108702938(plcd4.S) 108718712(plcd1.L) 108719811(plcd1.S) 735225(plcd4.L)
XTR: 100379715(plcd4) 100488677(plcd1) 100497993(plcd3)
NPR: 108784616(PLCD1) 108785980(PLCD3)
DRE: 337489(plcd1b) 555443(plcd1a) 562569(plcd3b) 565669(plcd4a) 569040(plcd3a)
TRU: 101062624(plcd1) 101066005 101076189(plcd3) 101077179(plcd4) 101078575
SFM: 108919945(plcd3) 108924218(plcd4) 108928009 108934038(plcd1) 108941601
LCM: 102347797(PLCD1) 102348562(PLCD3) 102349822 102354402(PLCD4)
CIN: 100185660
SPU: 100891267(PLCdsu) 494023(plcd)
APLC: 110990341
ZNE: 110830423
FCD: 110845159
TUT: 107366993
CEL: CELE_R05G6.8(plc-4)
CBR: CBG05896(Cbr-plc-4)
BMY: Bm1_31705
TSP: Tsp_07594
CRG: 105342681
MYI: 110459893
OBI: 106880478
LAK: 106162304
HMG: 100198602
ATH: AT2G40116 AT3G08510(PLC2) AT3G55940 AT4G38530(PLC1) AT5G58670(PLC1) AT5G58690(PLC5) AT5G58700(PLC4)
LJA: Lj0g3v0130579.1(Lj0g3v0130579.1) Lj0g3v0130589.1(Lj0g3v0130589.1) Lj0g3v0148389.1(Lj0g3v0148389.1) Lj0g3v0189439.1(Lj0g3v0189439.1) Lj0g3v0189439.2(Lj0g3v0189439.2) Lj2g3v2256390.1(Lj2g3v2256390.1) Lj2g3v2256400.1(Lj2g3v2256400.1) Lj2g3v2747660.1(Lj2g3v2747660.1) Lj2g3v2747660.2(Lj2g3v2747660.2) Lj2g3v2748690.1(Lj2g3v2748690.1) Lj6g3v0521600.1(Lj6g3v0521600.1) Lj6g3v0521600.2(Lj6g3v0521600.2) Lj6g3v0521600.3(Lj6g3v0521600.3) Lj6g3v0521670.1(Lj6g3v0521670.1)
DOSA: Os03t0289300-00(Os03g0289300) Os05t0127200-01(Os05g0127200) Os07t0694000-01(Os07g0694000) Os12t0562400-00(Os12g0562400)
ATS: 109738024(LOC109738024) 109738751(LOC109738751) 109747792(LOC109747792) 109748162(LOC109748162) 109756963(LOC109756963) 109762675(LOC109762675) 109766552(LOC109766552) 109771034(LOC109771034)
SCE: YPL268W(PLC1)
ERC: Ecym_3005
KMX: KLMA_80017(plc1)
NCS: NCAS_0D02230(NCAS0D02230)
NDI: NDAI_0I02690(NDAI0I02690)
TPF: TPHA_0J00210(TPHA0J00210)
TBL: TBLA_0A07020(TBLA0A07020)
TDL: TDEL_0G04680(TDEL0G04680)
KAF: KAFR_0B06460(KAFR0B06460)
PIC: PICST_42966(PLC1)
CAL: CAALFM_C703710CA(PLC1)
CDU: CD36_73380(PLC1)
SLB: AWJ20_1237(PLC1)
NCR: NCU01266
NTE: NEUTE1DRAFT127609(NEUTE1DRAFT_127609)
MGR: MGG_02444
MAW: MAC_06035
MAJ: MAA_06168
CMT: CCM_07897
BFU: BCIN_05g02840(Bcplc1)
MBE: MBM_09817
ANI: AN0664.2
ANG: ANI_1_884074(An08g06320)
ABE: ARB_06692
TVE: TRV_04036
PTE: PTT_08861
SPO: SPAC22F8.11(plc1)
CNE: CNC04820
CNB: CNBC2360
ABP: AGABI1DRAFT129320(AGABI1DRAFT_129320) AGABI1DRAFT72480(AGABI1DRAFT_72480)
ABV: AGABI2DRAFT120986(AGABI2DRAFT_120986) AGABI2DRAFT212030(AGABI2DRAFT_212030)
MGL: MGL_2569
DDI: DDB_G0292736(plc)
DFA: DFA_07345 DFA_07346(plc)
TAN: TA06965
TPV: TP01_0775
BBO: BBOV_IV011070(23.m06338)
CPV: cgd4_2560
SMIN: v1.2.010004.t1(symbB.v1.2.010004.t1) v1.2.033641.t1(symbB.v1.2.033641.t1)
SPAR: SPRG_04373
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Suh PG, Park JI, Manzoli L, Cocco L, Peak JC, Katan M, Fukami K, Kataoka T, Yun S, Ryu SH
  Title
Multiple roles of phosphoinositide-specific phospholipase C isozymes.
  Journal
BMB Rep 41:415-34 (2008)

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